Promoting clinical research to medically underserved communities: Current practices and perceptions about clinical trial recruiting strategies

Contemporary Clinical Trials

Volumn 41, Issue , 2015, Pages 39-44

  Tanner, Andrea ^a   Kim, Sei Hill ^a   Friedman, Daniela B ^a   Foster, Caroline ^b   Bergeron, Caroline D ^a  

^a UNIVERSITY OF SOUTH CAROLINA   (United States)

^b Department of Teacher Education and Department of Sociology and Anthropology   (United States)

Author keywords

Clinical trial; Health promotion; Recruitment; Research participation

Indexed keywords

AFRICAN AMERICAN; ARTICLE; AWARENESS; CLINICAL PRACTICE; CLINICAL RESEARCH; CLINICAL TRIAL (TOPIC); HEALTH PERSONNEL ATTITUDE; HEALTH SURVEY; HUMAN; MEDICALLY UNDERSERVED; ONLINE SYSTEM; PATIENT PARTICIPATION; PERCEPTION; PHYSICIAN; REFUSAL TO PARTICIPATE; RESEARCH SUBJECT; RURAL POPULATION; TELECOMMUNICATION; TELEVISION; UNIVERSITY HOSPITAL; HEALTH CARE PLANNING; PATIENT SELECTION; PERSONNEL; PROCEDURES; PSYCHOLOGY;

ACADEMIC MEDICAL CENTERS; AFRICAN AMERICANS; ATTITUDE OF HEALTH PERSONNEL; CLINICAL TRIALS AS TOPIC; HUMANS; MEDICALLY UNDERSERVED AREA; PATIENT SELECTION; RESEARCH PERSONNEL; RURAL POPULATION;

EID: 84921341465     PISSN: 15517144     EISSN: 15592030     Source Type: Journal    
DOI: 10.1016/j.cct.2014.12.010     Document Type: Article

References (37)

1. Felder T.M., Pena G.D., Chapital B.F. Peer reviewed: disparities in cancer clinical trials: an analysis of comprehensive cancer control plans. Prev Chronic Dis 2009, 6(4).
2. Weckstein D.J., Thomas C.A., Emery I.F., Shea B.F., Fleury A., White M.E., et al. Assessment of perceived cost to the patient and other barriers to clinical trial participation. J Oncol Pract 2011, 7(5):330-333.
3. Embi P.J., Jain A., Clark J., Bizjack S., Hornung R., Harris C.M. Effect of a clinical trial alert system on physician participation in trial recruitment. Arch Intern Med 2005, 165(19). [Epub 2005/10/26. PubMed PMID: 16246994; PubMed Central PMCID: PMC1343501]. 10.1001/archinte.165.19.2272.
4. National Institutes of Health Learn about clinical studies [cited 2013 March 1]. Available from:. http://clinicaltrials.gov/ct2/info/understand.
5. National Institutes of Health NIH policy and guidelines on the inclusion of women and minorities as subjects in clinical research-amended [cited 2013 March 1]. Available from:. http://grants.nih.gov/grants/funding/women_min/guidelines_amended_10_2001.htm.
6. Ford J.G., Howerton M.W., Bolen S., Gary T.L., Lai G.Y., Tilburt J., et al. Knowledge and access to information on recruitment of underrepresented populations to cancer clinical trials. Evid Rep Technol Assess (Summ) 2005, (122):1-11. [Epub 2005/07/02. PubMed PMID: 15989377].
7. Heller C., Balls-Berry J.E., Nery J.D., Erwin P.J., Littleton D., Kim M., et al. Strategies addressing barriers to clinical trial enrollment of underrepresented populations: a systematic review. Contemp Clin Trials 2014, [Epub 2014/08/19. PubMed PMID: 25131812]. 10.1016/j.cct.2014.08.004.
8. Tanner A., Kim S.H., Friedman D.B., Foster C., Bergeron C.D. Barriers to medical research participation as perceived by clinical trial investigators: communicating with rural and African American communities. J Health Commun 2014, 1-9. [Epub 2014/09/11. PubMed PMID: 25204763]. 10.1080/10810730.2014.908985.
9. Mendoza D.B., Williams M.T., Chapman L.K., Powers M. Minority inclusion in randomized clinical trials of panic disorder. J Anxiety Disord 2012, 26(5):574-582. [Epub 2012/03/27. PubMed PMID: 22445317]. 10.1016/j.janxdis.2012.02.011.
10. Vesey G.A. A successful strategy for recruitment and retention of Black Elders in applied research. Afr Am Res Perspect 2002, 8(2):40-56.
11. Williams M.T., Beckmann-Mendez D.A., Turkheimer E. Cultural barriers to African American participation in anxiety disorders research. J Natl Med Assoc 2013, 105(1):33-41. [Epub 2013/07/19. PubMed PMID: 23862294; PubMed Central PMCID: PMC4161612].
12. Williams M.T., Proetto D., Casiano D., Franklin M.E. Recruitment of a hidden population: African Americans with obsessive-compulsive disorder. Contemp Clin Trials 2012, 33(1):67-75. [Epub 2011/10/11. PubMed PMID: 21983626; PubMed Central PMCID: PMC3253913]. 10.1016/j.cct.2011.09.001.
13. Quinn G.P., Bell B.A., Bell M.Y., Caraway V.D., Conforte D., Graci L.B., et al. The guinea pig syndrome: improving clinical trial participation among thoracic patients. J Thorac Oncol 2007, 2:191-196.
14. Guadagnolo B.A., Petereit D.G., Helbig P., Koop D., Kussman P., Dunn E.F., et al. Involving American Indians and medically underserved rural populations in cancer clinical trials. Clin Trials 2009, 6:610-617.
15. Branson R.D., Davis K., Butler K.L. African Americans' participation in clinical research: importance, barriers, and solutions. Am J Surg 2007, 193(1):32-39. [discussion 40. Epub 2006/12/26. S0002-9610(05)00873-1 [pii] PubMed PMID: 17188084]. 10.1016/j.amjsurg.2005.11.007.
16. McComas K.A., Yang Z., Gay G.K., Leonard J.P., Dannenberg A.J., Dillon H. Individuals' willingness to talk to their doctors about clinical trial enrollment. J Health Commun 2010, 15(2):189-204. [Epub 2010/04/15. PubMed PMID: 20390986]. 10.1080/10810730903528058.
17. Castel P., Negrier S., Boissel J.P. Why don't cancer patients enter clinical trials? A review. Eur J Cancer 2006, 42(12):1744-1748. [Epub 2006/06/17. PubMed PMID: 16777404]. 10.1016/j.ejca.2005.10.033.
18. Ford L.G., Minasian L.M., McCaskill Stevens W., Pisano E.D., Sullivan D., Smith R.A. Prevention and early detection clinical trials: opportunities for primary careproviders and their patients. CA Cancer J Clin 2009, 53(2):82-101.
19. Friedman D.B., Hooker S.P., Wilcox S., Burroughs E.L., Rheaume C.E. African American men's perspectives on promoting physical activity: "we're not that difficult to figure out!". J Health Commun 2012, [online first]. 10.1080/10810730.2012.665424.
20. Friedman D.B., Kim S.H., Tanner A., Bergeron C.D., Foster C., General K. How are we communicating about clinical trials?: an assessment of the content and readability of recruitment resources. Contemp Clin Trials 2014, 38(2):275-283. [Epub 2014/05/20. PubMed PMID: 24836075]. 10.1016/j.cct.2014.05.004.
21. Mackenzie I.S., Wei L., Rutherford D., Findlay E.A., Saywood W., Campbell M.K., et al. Promoting public awareness of randomised clinical trials using the media: the 'Get Randomised' campaign. Br J Clin Pharmacol 2010, 69(2):128-135. [Epub 2010/03/18. PubMed PMID: 20233175; PubMed Central PMCID: PMC2817445]. 10.1111/j.1365-2125.2009.03561.x.
22. Lai G.Y., Gary T.L., Tilburt J., Bolen S., Baffi C., Wilson R.F., et al. Effectiveness of strategies to recruit underrepresented populations into cancer clinical trials. Clin Trials 2006, 3(2):133-141. [Epub 2006/06/16. PubMed PMID: 16773955].
23. Nichols L., Martindale-Adams J., Burns R., Coon D., Ory M., Mahoney D., et al. Social marketing as a framework for recruitment: illustrations from the REACH study. J Aging Health 2004, 16(5 Suppl.):157S-176S. [Epub 2004/09/28. PubMed PMID: 15448292; PubMed Central PMCID: PMC2579268]. 10.1177/0898264304269727.
24. U.S. Census Bureau. 2010.
25. U.S. Census Bureau South Carolina State & County Quick Facts 2012.
26. SC Rural Health Research Center. State rural plan for South Carolina 2008, SC Rural Health Research Center.
27. Wells K.J., Quinn G.P., Meade C.D., Fletcher M., Tyson D.M., Jim H., et al. Development of a cancer clinical trials multi-media intervention: clinical trials: are they right for you?. Patient Educ Couns 2012, 88(2):232-240. [Epub 2012/04/25. PubMed PMID: 22525803]. 10.1016/j.pec.2012.03.011.
28. Friedman D.B., Bergeron C.D., Foster C., Tanner A., Kim S.H. What do people really know and think about clinical trials? A comparison of rural and urban communities in the South. J Community Health 2013, 38(4):642-651. Epub 2013/03/08. PubMed PMID: 23468319. 10.1007/s10900-013-9659-z.
29. The burden of heart disease and stroke in South Carolina 2010, South Carolina Department of Health and Environmental Control: Heart Disease and Stroke Prevention Division, Columbia, SC.
30. Getz KA. Restoring public confidence in clinical research: Lessons from the organ donation sector. The Monitor [Internet]. 2008 March 5, 2013; (September): [59-62 pp.]. Available from: http://216.147.199.31/Monitor/2008September/Getz2.pdf.
31. Len-Rios M.E., Qiu Q. Negative articles predict clinical trial reluctance. Newsp Res J 2007, 28:24-39.
32. Bergeron C., Foster C., Friedman D.B., Tanner A., Kim S.-H. Clinical trial recruitment in rural South Carolina: a comparison of investigators' perceptions and potential participant eligibility. Rural Remote Health 2013, 13(4):2567.
33. Coleman-Phox K., Laraia B.A., Adler N., Vieten C., Thomas M., Epel E. Peer reviewed: recruitment and retention of pregnant women for a behavioral intervention: lessons from the Maternal Adiposity, Metabolism, and Stress (MAMAS) study. Prev Chronic Dis 2013, 10.
34. Bonevski B., Magin P., Horton G., Foster M., Girgis A. Response rates in GP surveys: trialing two recruitment strategies. Aust Fam Physician 2011, 40(6):1.
35. Andreason A. Marketing social change: changing behavior to promote health, social development, and the environment 1995, Jossey-Bass, San Francisco.
36. Friedman D.B., Corwin S.J., Dominick G.M., Rose I.D. African American men's understanding and perceptions about prostate cancer: why multiple dimensions of health literacy are important in cancer communication. J Community Health 2009, 34(5):449-460. [Epub 2009/06/12. PubMed PMID: 19517223]. 10.1007/s10900-009-9167-3.
37. Comis R.L., Crowley J., Unger J., Marinucci D., Catalano R., Colaizzi D., et al. Baseline study of patient accrual onto publicly sponsored U.S. cancer clinical trials: an analysis conducted for the global access project of the National Patient Advocate Foundation 2006, Coalition of Cancer Cooperative Groups, Philadelphia, PA, [April 21, 2009. Available from: http://www.npaf.org/images/pdf/gap/sept_2006/cccg.pdf].