Decellularized tracheal extracellular matrix supports epithelial migration, differentiation, and function

Tissue Engineering - Part A

Volumn 21, Issue 1-2, 2015, Pages 75-84

  Kutten, Johannes C ^a   McGovern, David ^b   Hobson, Christopher M ^c,d   Luffy, Sarah A ^c,d   Nieponice, Alejandro ^d   Tobita, Kimimasa ^a,e   Francis, Richard J ^a   Reynolds, Susan D ^f   Isenberg, Jeffrey S ^a   Gilbert, Thomas W ^c,g  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c University of Pittsburgh   (United States)

^d MCGOWAN INSTITUTE FOR REGENERATIVE MEDICINE   (United States)

^e CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^f DEPARTMENT OF MEDICINE   (United States)

^g ACell Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPUTERIZED TOMOGRAPHY; MAMMALS;

APPROPRIATE MODELS; DECELLULARIZED TRACHEAS; EPITHELIAL MIGRATION; EXTRACELLULAR MATRICES; FUNCTIONAL REGENERATION; RE-EPITHELIALIZATION; SMALL ANIMAL MODEL; TRACHEAL TRANSPLANTATION;

GRAFTS;

ALCOHOL; PERACETIC ACID; SODIUM CHLORIDE; TRITON X 100; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CARTILAGINOUS TISSUE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MIGRATION; CHONDROGENESIS; CILIARY MOTILITY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; DECELLULARIZED TRACHEAL EXTRACELLULAR MATRIX; DISINFECTION; EPITHELIUM CELL; EPITHELIZATION; EXPLANT; EXTRACELLULAR MATRIX; FEMALE; GAMMA IRRADIATION; MOUSE; NONHUMAN; ORTHOTOPIC TRANSPLANTATION; POST TREATMENT SURVIVAL; PRIORITY JOURNAL; RADIATION STERILIZATION; TRACHEA MUCOSA; TRACHEA PROSTHESIS; VIDEO MICROSCOPY; WEIGHT GAIN; ANIMAL; C57BL MOUSE; CELL MOTION; CHEMISTRY; CYTOLOGY; EUKARYOTIC FLAGELLUM; METABOLISM; MICRO-COMPUTED TOMOGRAPHY; PLASTIC SURGERY; RADIOGRAPHY; SURGERY; TISSUE SCAFFOLD; TRACHEA; TRANSPLANTATION; VACUUM;

ANIMALIA; MURINAE; MUS;

ANIMALS; CELL DIFFERENTIATION; CELL MOVEMENT; CILIA; EPITHELIAL CELLS; EXTRACELLULAR MATRIX; FEMALE; MICE, INBRED C57BL; RECONSTRUCTIVE SURGICAL PROCEDURES; TISSUE SCAFFOLDS; TRACHEA; VACUUM; X-RAY MICROTOMOGRAPHY;

EID: 84921328103     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2014.0089     Document Type: Article

References (35)

1. Treatment of childhood tuberculosis: Consensus Statement of IAP Working Group. Indian Academy of Pediatrics. Indian Pediatr 34, 1093, 1997.
2. Kocyildirim, E., Kanani, M., Roebuck, D., Wallis, C., McLaren, C., Noctor, C., et al. Long-segment tracheal stenosis: slide tracheoplasty and a multidisciplinary approach improve outcomes and reduce costs. J Thorac Car-diovasc Surg 128, 876, 2004.
3. Wurtz, A., and Kipnis, E. Tissue-engineered airway in the clinical setting: a call for information disclosure. Clin Pharmacol Ther 91, 973; author reply 4, 2012.
4. Birchall, M., and Macchiarini, P. Airway transplantation: a debate worth having? Transplantation 85, 1075, 2008.
5. Okumura, N., Nakamura, T., Natsume, T., Tomihata, K., Ikada, Y., and Shimizu, Y. Experimental study on a new tracheal prosthesis made from collagen-conjugated mesh. J Thorac Cardiovasc Surg 108, 337, 1994.
6. Teramachi, M., Okumura, N., Nakamura, T., Yamamoto, Y., Kiyotani, T., Takimoto, Y., et al. Intrathoracic tracheal reconstruction with a collagen-conjugated prosthesis: evaluation of the efficacy of omental wrapping. J Thorac Cardiovasc Surg 113, 701, 1997.
7. Macchiarini, P., Jungebluth, P., Go, T., Asnaghi, M.A., Rees, L.E., Cogan, T.A., et al. Clinical transplantation of a tissue-engineered airway. Lancet 372, 2023, 2008.
8. Berg, M., Ejnell, H., Kovacs, A., Nayakawde, N., Patil, P.B., Joshi, M., et al. Replacement of a tracheal stenosis with a tissue-engineered human trachea using autologous stem cells: a case report. Tissue Eng Part A 20, 389, 2014.
9. Omori, K., Nakamura, T., Kanemaru, S., Asato, R., Ya-mashita, M., Tanaka, S., et al. Regenerative medicine of the trachea: the first human case. Ann Otol Rhinol Laryngol 114, 429, 2005.
10. Azorin, J.F., Bertin, F., Martinod, E., and Laskar, M. Tra-cheal replacement with an aortic autograft. Eur J Cardi-othorac Surg 29, 261, 2006.
11. Roomans, G.M. Tissue engineering and the use of stem/progenitor cells for airway epithelium repair. Eur Cells Mater 19, 284, 2010.
12. Gonfiotti, A., Jaus, M.O., Barale, D., Baiguera, S., Comin, C., Lavorini, F., et al. The first tissue-engineered airway transplantation: 5-year follow-up results. Lancet 383, 238, 2014.
13. Gilbert, T.W., Sellaro, T.L., and Badylak, S.F. Decellular-ization of tissues and organs. Biomaterials 27, 3675, 2006.
14. Gilbert, T.W. Strategies for tissue and organ decellular-ization. J Cell Biochem 113, 2217, 2012.
15. Baiguera, S., Del Gaudio, C., Jaus, M.O., Polizzi, L., Gonfiotti, A., Comin, C.E., et al. Long-term changes to in vitro preserved bioengineered human trachea and their implications for decellularized tissues. Biomaterials 33, 3662, 2012.
16. Baiguera, S., Jungebluth, P., Burns, A., Mavilia, C., Haag, J., De Coppi, P., et al. Tissue engineered human tracheas for in vivo implantation. Biomaterials 31, 8931, 2010.
17. Curcio, E., Macchiarini, P., and De Bartolo, L. Oxygen mass transfer in a human tissue-engineered trachea. Bio-materials 31, 5131, 2010.
18. Macchiarini, P. [First successful trachea transplantation. New trachea from the bioreactor (interview by Dr. Judith Neumaier)]. MMW Fortschr Med 151, 6, 2009.
19. Macchiarini, P., Walles, T., Biancosino, C., and Mertsch-ing, H. First human transplantation of a bioengineered airway tissue. J Thorac Cardiovasc Surg 128, 638, 2004.
20. Mertsching, H., Walles, T., and Macchiarini, P. Replacement of the trachea with an autologous aortic graft. Ann Thorac Surg 78, 1132, author reply 3, 2004.
21. National Research Council (U.S.). Committee for the Update of the Guide for the Care and Use of Laboratory Animals. Institute for Laboratory Animal Research (U.S.), National Academies Press (U.S.). Guide for the Care and Use of Laboratory Animals, 8th ed. Washington, DC: National Academies Press, 2011, pp. xxv, 220.
22. Hua, X., Deuse, T., Tang-Quan, K.R., Robbins, R.C., Reichenspurner, H., and Schrepfer, S. Heterotopic and or-thotopic tracheal transplantation in mice used as models to study the development of obliterative airway disease. J Vis Exp 35, pii: 1437, 2010.
23. Genden, E.M., Boros, P., Liu, J., Bromberg, J.S., and Mayer, L. Orthotopic tracheal transplantation in the murine model. Transplantation 73, 1420, 2002.
24. Genden, E.M., Iskander, A., Bromberg, J.S., and Mayer, L. The kinetics and pattern of tracheal allograft re-epithelial-ization. Am J Respir Cell Mol Biol 28, 673, 2003.
25. Genden, E.M., Iskander, A.J., Bromberg, J.S., and Mayer, L. Orthotopic tracheal allografts undergo reepithelialization with recipient-derived epithelium. Arch Otolaryngol Head Neck Surg 129, 118, 2003.
26. Grillo, H.C. Tracheal replacement: a critical review. Ann Thorac Surg 73, 1995, 2002.
27. Crapo, P.M., Gilbert, T.W., and Badylak, S.F. An overview of tissue and whole organ decellularization processes. Biomaterials 32, 3233, 2011.
28. Zang, M., Zhang, Q., Chang, E.I., Mathur, A.B., and Yu, P. Decellularized tracheal matrix scaffold for tracheal tissue engineering: in vivo host response. Plast Reconstruct Surg 132, 549e, 2013.
29. Remlinger, N.T., Czajka, C.A., Juhas, M.E., Vorp, D.A., Stolz, D.B., Badylak, S.F., et al. Hydrated xenogeneic de-cellularized tracheal matrix as a scaffold for tracheal reconstruction. Biomaterials 31, 3520, 2010.
30. Gilbert, T.W., Gilbert, S., Madden, M., Reynolds, S.D., and Badylak, S.F. Morphologic assessment of extracellular matrix scaffolds for patch tracheoplasty in a canine model. Ann Thorac Surg 86, 967, discussion 74, 2008.
31. Jungebluth, P., Go, T., Asnaghi, A., Bellini, S., Martorell, J., Calore, C., et al. Structural and morphologic evaluation of a novel detergent-enzymatic tissue-engineered tracheal tubular matrix. J Thorac Cardiovasc Surg 138, 586, discussion 92, 2009.
32. Musah, S., Chen, J., and Hoyle, G.W. Repair of tracheal epithelium by basal cells after chlorine-induced injury. Respir Res 13, 107, 2012.
33. Cole, B.B., Smith, R.W., Jenkins, K.M., Graham, B.B., Reynolds, P.R., and Reynolds, S.D. Tracheal Basal cells: a facultative progenitor cell pool. Am J Pathol 177, 362, 2010.
34. Hajj, R., Baranek, T., Le Naour, R., Lesimple, P., Puchelle, E., and Coraux, C. Basal cells of the human adult airway surface epithelium retain transit-Amplifying cell properties. Stem Cells 25, 139, 2007.
35. Rock, J.R., Onaitis, M.W., Rawlins, E.L., Lu, Y., Clark, C.P., Xue, Y., et al. Basal cells as stem cells of the mouse trachea and human airway epithelium. Proc Natl Acad Sci USA 106, 12771, 2009.