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Volumn 358, Issue 1, 2015, Pages 37-42

Estrogen receptors β1 and β2 are associated with distinct responses of estrogen receptor α-positive breast carcinoma to adjuvant endocrine therapy

Author keywords

Breast carcinoma; Endocrine therapy; ER 1; ER 2; Immunohistochemistry

Indexed keywords

ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ESTROGEN RECEPTOR BETA1; ESTROGEN RECEPTOR BETA2; UNCLASSIFIED DRUG;

EID: 84921288851     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.12.022     Document Type: Article
Times cited : (7)

References (33)
  • 1
    • 84876666536 scopus 로고    scopus 로고
    • Biomarkers for the clinical management of breast cancer: international perspective
    • Patani N., Martin L.A., Dowsett M. Biomarkers for the clinical management of breast cancer: international perspective. Int. J. Cancer 2013, 133(1):1-13. 10.1002/ijc.27997.
    • (2013) Int. J. Cancer , vol.133 , Issue.1 , pp. 1-13
    • Patani, N.1    Martin, L.A.2    Dowsett, M.3
  • 2
    • 79960832381 scopus 로고    scopus 로고
    • The different roles of ER subtypes in cancer biology and therapy
    • Thomas C., Gustafsson J.Å. The different roles of ER subtypes in cancer biology and therapy. Nat. Rev. Cancer 2011, 11(8):597-608. 10.1038/nrc3093.
    • (2011) Nat. Rev. Cancer , vol.11 , Issue.8 , pp. 597-608
    • Thomas, C.1    Gustafsson, J.Å.2
  • 4
    • 0032145924 scopus 로고    scopus 로고
    • Molecular cloning and characterization of human estrogen receptor betacx: a potential inhibitor of estrogen action in human
    • Ogawa S., Inoue S., Watanabe T., Orimo A., Hosoi T., Ouchi Y., et al. Molecular cloning and characterization of human estrogen receptor betacx: a potential inhibitor of estrogen action in human. Nucleic Acids Res 1998, 26(15):3505-3512. 10.1093/nar/26.15.3505.
    • (1998) Nucleic Acids Res , vol.26 , Issue.15 , pp. 3505-3512
    • Ogawa, S.1    Inoue, S.2    Watanabe, T.3    Orimo, A.4    Hosoi, T.5    Ouchi, Y.6
  • 5
    • 33748346434 scopus 로고    scopus 로고
    • Estrogen receptor (ER)-beta isoforms: a key to understanding ER-beta signaling
    • Leung Y.K., Mak P., Hassan S., Ho S.M. Estrogen receptor (ER)-beta isoforms: a key to understanding ER-beta signaling. Proc. Natl. Acad. Sci. U.S.A. 2006, 103(35):13162-13167. 10.1073/pnas.0605676103.
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , Issue.35 , pp. 13162-13167
    • Leung, Y.K.1    Mak, P.2    Hassan, S.3    Ho, S.M.4
  • 6
    • 84856294079 scopus 로고    scopus 로고
    • The role of estrogen receptor-β in breast cancer
    • Murphy L.C., Leygue E. The role of estrogen receptor-β in breast cancer. Semin. Reprod. Med 2012, 30(1):5-13. 10.1055/s-0031-1299592.
    • (2012) Semin. Reprod. Med , vol.30 , Issue.1 , pp. 5-13
    • Murphy, L.C.1    Leygue, E.2
  • 7
    • 84863066879 scopus 로고    scopus 로고
    • Identification of estrogen receptor dimer selective ligands reveals growth-inhibitory effects on cells that co-express ERα and ERβ
    • Powell E., Shanle E., Brinkman A., Li J., Keles S., Wisinski K.B., et al. Identification of estrogen receptor dimer selective ligands reveals growth-inhibitory effects on cells that co-express ERα and ERβ. PLoS ONE 2012, 7(2):e30993. 10.1371/journal.pone.0030993.
    • (2012) PLoS ONE , vol.7 , Issue.2 , pp. e30993
    • Powell, E.1    Shanle, E.2    Brinkman, A.3    Li, J.4    Keles, S.5    Wisinski, K.B.6
  • 8
    • 0042388370 scopus 로고    scopus 로고
    • Estrogen receptor (ER) beta1 and ERbetacx/beta2 inhibit ERalpha function differently in breast cancer cell line MCF7
    • Omoto Y., Eguchi H., Yamamoto-Yamaguchi Y., Hayashi S. Estrogen receptor (ER) beta1 and ERbetacx/beta2 inhibit ERalpha function differently in breast cancer cell line MCF7. Oncogene 2003, 22(32):5011-5020. 10.1038/sj.onc.1206787.
    • (2003) Oncogene , vol.22 , Issue.32 , pp. 5011-5020
    • Omoto, Y.1    Eguchi, H.2    Yamamoto-Yamaguchi, Y.3    Hayashi, S.4
  • 9
    • 1642535535 scopus 로고    scopus 로고
    • Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest
    • Paruthiyil S., Parmar H., Kerekatte V., Cunha G.R., Firestone G.L., Leitman D.C. Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest. Cancer Res 2004, 64(1):423-428. 10.1158/0008-5472.CAN-03-2446.
    • (2004) Cancer Res , vol.64 , Issue.1 , pp. 423-428
    • Paruthiyil, S.1    Parmar, H.2    Kerekatte, V.3    Cunha, G.R.4    Firestone, G.L.5    Leitman, D.C.6
  • 10
    • 1242300083 scopus 로고    scopus 로고
    • Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D
    • Ström A., Hartman J., Foster J.S., Kietz S., Wimalasena J., Gustafsson J.A. Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D. Proc. Natl. Acad. Sci. U.S.A. 2004, 101(6):1566-1571. 10.1073/pnas.0308319100.
    • (2004) Proc. Natl. Acad. Sci. U.S.A. , vol.101 , Issue.6 , pp. 1566-1571
    • Ström, A.1    Hartman, J.2    Foster, J.S.3    Kietz, S.4    Wimalasena, J.5    Gustafsson, J.A.6
  • 11
    • 34248586255 scopus 로고    scopus 로고
    • Estrogen receptor beta2 negatively regulates the transactivation of estrogen receptor alpha in human breast cancer cells
    • Zhao C., Matthews J., Tujague M., Wan J., Ström A., Toresson G., et al. Estrogen receptor beta2 negatively regulates the transactivation of estrogen receptor alpha in human breast cancer cells. Cancer Res 2007, 67(8):3955-3962. 10.1158/0008-5472.CAN-06-3505.
    • (2007) Cancer Res , vol.67 , Issue.8 , pp. 3955-3962
    • Zhao, C.1    Matthews, J.2    Tujague, M.3    Wan, J.4    Ström, A.5    Toresson, G.6
  • 12
    • 49249129393 scopus 로고    scopus 로고
    • Clinical importance of estrogen receptor-beta evaluation in breast cancer patients treated with adjuvant tamoxifen therapy
    • Honma N., Horii R., Iwase T., Saji S., Younes M., Takubo K., et al. Clinical importance of estrogen receptor-beta evaluation in breast cancer patients treated with adjuvant tamoxifen therapy. J. Clin. Oncol 2008, 26(22):3727-3734. 10.1200/JCO.2007.14.2968.
    • (2008) J. Clin. Oncol , vol.26 , Issue.22 , pp. 3727-3734
    • Honma, N.1    Horii, R.2    Iwase, T.3    Saji, S.4    Younes, M.5    Takubo, K.6
  • 13
    • 2442553813 scopus 로고    scopus 로고
    • The favourable prognostic value of oestrogen receptor beta immunohistochemical expression in breast cancer
    • Nakopoulou L., Lazaris A.C., Panayotopoulou E.G., Giannopoulou I., Givalos N., Markaki S., et al. The favourable prognostic value of oestrogen receptor beta immunohistochemical expression in breast cancer. J. Clin. Pathol 2004, 57(5):523-528. 10.1136/jcp.2003.008599.
    • (2004) J. Clin. Pathol , vol.57 , Issue.5 , pp. 523-528
    • Nakopoulou, L.1    Lazaris, A.C.2    Panayotopoulou, E.G.3    Giannopoulou, I.4    Givalos, N.5    Markaki, S.6
  • 14
    • 59449088889 scopus 로고    scopus 로고
    • A divergent role for estrogen receptor-beta in node-positive and node-negative breast cancer classified according to molecular subtypes: an observational prospective study
    • Novelli F., Milella M., Melucci E., Di Benedetto A., Sperduti I., Perrone-Donnorso R., et al. A divergent role for estrogen receptor-beta in node-positive and node-negative breast cancer classified according to molecular subtypes: an observational prospective study. Breast Cancer Res 2008, 10(5):R74. 10.1186/bcr2139.
    • (2008) Breast Cancer Res , vol.10 , Issue.5 , pp. R74
    • Novelli, F.1    Milella, M.2    Melucci, E.3    Di Benedetto, A.4    Sperduti, I.5    Perrone-Donnorso, R.6
  • 15
    • 33646498981 scopus 로고    scopus 로고
    • Oestrogen receptor beta and neoadjuvant therapy with tamoxifen: prediction of response and effects of treatment
    • Miller W.R., Anderson T.J., Dixon J.M., Saunders P.T. Oestrogen receptor beta and neoadjuvant therapy with tamoxifen: prediction of response and effects of treatment. Br. J. Cancer 2006, 94(9):1333-1338. 10.1038/sj.bjc.6603082.
    • (2006) Br. J. Cancer , vol.94 , Issue.9 , pp. 1333-1338
    • Miller, W.R.1    Anderson, T.J.2    Dixon, J.M.3    Saunders, P.T.4
  • 16
    • 0037011662 scopus 로고    scopus 로고
    • Relationship of coregulator and oestrogen receptor isoform expression to de novo tamoxifen resistance in human breast cancer
    • Murphy L.C., Leygue E., Niu Y., Snell L., Ho S.M., Watson P.H. Relationship of coregulator and oestrogen receptor isoform expression to de novo tamoxifen resistance in human breast cancer. Br. J. Cancer 2002, 87(12):1411-1416. 10.1038/sj.bjc.6600654.
    • (2002) Br. J. Cancer , vol.87 , Issue.12 , pp. 1411-1416
    • Murphy, L.C.1    Leygue, E.2    Niu, Y.3    Snell, L.4    Ho, S.M.5    Watson, P.H.6
  • 17
    • 9144226888 scopus 로고    scopus 로고
    • Wild-type oestrogen receptor beta (ERbeta1) mRNA and protein expression in Tamoxifen-treated post-menopausal breast cancers
    • O'Neill P.A., Davies M.P., Shaaban A.M., Innes H., Torevell A., Sibson D.R., et al. Wild-type oestrogen receptor beta (ERbeta1) mRNA and protein expression in Tamoxifen-treated post-menopausal breast cancers. Br. J. Cancer 2004, 91(9):1694-1702. 10.1038/sj.bjc.6602183.
    • (2004) Br. J. Cancer , vol.91 , Issue.9 , pp. 1694-1702
    • O'Neill, P.A.1    Davies, M.P.2    Shaaban, A.M.3    Innes, H.4    Torevell, A.5    Sibson, D.R.6
  • 18
    • 52649152266 scopus 로고    scopus 로고
    • Nuclear and cytoplasmic expression of ERbeta1, ERbeta2, and ERbeta5 identifies distinct prognostic outcome for breast cancer patients
    • Shaaban A.M., Green A.R., Karthik S., Alizadeh Y., Hughes T.A., Harkins L., et al. Nuclear and cytoplasmic expression of ERbeta1, ERbeta2, and ERbeta5 identifies distinct prognostic outcome for breast cancer patients. Clin. Cancer Res 2008, 14(16):5228-5235. 10.1158/1078-0432.CCR-07-4528.
    • (2008) Clin. Cancer Res , vol.14 , Issue.16 , pp. 5228-5235
    • Shaaban, A.M.1    Green, A.R.2    Karthik, S.3    Alizadeh, Y.4    Hughes, T.A.5    Harkins, L.6
  • 19
    • 33644873967 scopus 로고    scopus 로고
    • Phosphorylation of estrogen receptor alpha serine 167 is predictive of response to endocrine therapy and increases postrelapse survival in metastatic breast cancer
    • Yamashita H., Nishio M., Kobayashi S., Ando Y., Sugiura H., Zhang Z., et al. Phosphorylation of estrogen receptor alpha serine 167 is predictive of response to endocrine therapy and increases postrelapse survival in metastatic breast cancer. Breast Cancer Res 2005, 7(5):R753-R764. 10.1186/bcr1285.
    • (2005) Breast Cancer Res , vol.7 , Issue.5 , pp. R753-R764
    • Yamashita, H.1    Nishio, M.2    Kobayashi, S.3    Ando, Y.4    Sugiura, H.5    Zhang, Z.6
  • 20
    • 0036735297 scopus 로고    scopus 로고
    • Expression of estrogen receptor (ER) (beta)cx protein in ER(alpha)-positive breast cancer: specific correlation with progesterone receptor
    • Saji S., Omoto Y., Shimizu C., Warner M., Hayashi Y., Horiguchi S., et al. Expression of estrogen receptor (ER) (beta)cx protein in ER(alpha)-positive breast cancer: specific correlation with progesterone receptor. Cancer Res 2002, 62(17):4849-4853.
    • (2002) Cancer Res , vol.62 , Issue.17 , pp. 4849-4853
    • Saji, S.1    Omoto, Y.2    Shimizu, C.3    Warner, M.4    Hayashi, Y.5    Horiguchi, S.6
  • 21
    • 4444254432 scopus 로고    scopus 로고
    • Estrogen receptor beta (ER beta) level but not its ER beta cx variant helps to predict tamoxifen resistance in breast cancer
    • Esslimani-Sahla M., Simony-Lafontaine J., Kramar A., Lavaill R., Mollevi C., Warner M., et al. Estrogen receptor beta (ER beta) level but not its ER beta cx variant helps to predict tamoxifen resistance in breast cancer. Clin. Cancer Res 2004, 10(17):5769-5776. 10.1158/1078-0432.CCR-04-0389.
    • (2004) Clin. Cancer Res , vol.10 , Issue.17 , pp. 5769-5776
    • Esslimani-Sahla, M.1    Simony-Lafontaine, J.2    Kramar, A.3    Lavaill, R.4    Mollevi, C.5    Warner, M.6
  • 22
    • 69049113999 scopus 로고    scopus 로고
    • Patterns and predictors of early recurrence in postmenopausal women with estrogen receptor-positive early breast cancer
    • Mansell J., Monypenny I.J., Skene A.I., Abram P., Carpenter R., Gattuso J.M., et al. Patterns and predictors of early recurrence in postmenopausal women with estrogen receptor-positive early breast cancer. Breast Cancer Res. Treat 2009, 117(1):91-98. 10.1007/s10549-008-0291-z.
    • (2009) Breast Cancer Res. Treat , vol.117 , Issue.1 , pp. 91-98
    • Mansell, J.1    Monypenny, I.J.2    Skene, A.I.3    Abram, P.4    Carpenter, R.5    Gattuso, J.M.6
  • 23
    • 85203363507 scopus 로고    scopus 로고
    • Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG)
    • Davies C., Godwin J., Gray R., Clarke M., Cutter D., et al. Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials. Lancet 2011, 378(9793):771-784. Early Breast Cancer Trialists' Collaborative Group (EBCTCG). 10.1016/S0140-6736(11)60993-8.
    • (2011) Lancet , vol.378 , Issue.9793 , pp. 771-784
    • Davies, C.1    Godwin, J.2    Gray, R.3    Clarke, M.4    Cutter, D.5
  • 24
    • 84920601089 scopus 로고    scopus 로고
    • Comparison of breast cancer recurrence and outcome patterns between patients treated from 1986 to 1992 and from 2004 to 2008
    • Epub ahead of print.
    • Cossetti R.J., Tyldesley S.K., Speers C.H., Zheng Y., Gelmon K.A. Comparison of breast cancer recurrence and outcome patterns between patients treated from 1986 to 1992 and from 2004 to 2008. J. Clin. Oncol 2014, Epub ahead of print]. JCO.2014.57.2461 [pii].
    • (2014) J. Clin. Oncol
    • Cossetti, R.J.1    Tyldesley, S.K.2    Speers, C.H.3    Zheng, Y.4    Gelmon, K.A.5
  • 25
    • 79960462107 scopus 로고    scopus 로고
    • Insights into ectopic estrogen receptor expression, nucleocytoplasmic distribution and interaction with chromatin obtained with new antibodies to estrogen receptors α and β
    • Chantzi N.I., Meligova A.K., Dhimolea E., Petrou C.C., Mitsiou D.J., Magafa V., et al. Insights into ectopic estrogen receptor expression, nucleocytoplasmic distribution and interaction with chromatin obtained with new antibodies to estrogen receptors α and β. Steroids 2011, 76(10-11):974-985. 10.1016/j.steroids.2011.05.010.
    • (2011) Steroids , vol.76 , Issue.10-11 , pp. 974-985
    • Chantzi, N.I.1    Meligova, A.K.2    Dhimolea, E.3    Petrou, C.C.4    Mitsiou, D.J.5    Magafa, V.6
  • 26
    • 84882608344 scopus 로고    scopus 로고
    • Estrogen receptor beta 2 is associated with poor prognosis in estrogen receptor alpha-negative breast carcinoma
    • Chantzi N.I., Tiniakos D.G., Palaiologou M., Goutas N., Filippidis T., Vassilaros S.D., et al. Estrogen receptor beta 2 is associated with poor prognosis in estrogen receptor alpha-negative breast carcinoma. J. Cancer Res. Clin. Oncol 2013, 139(9):1489-1498. 10.1007/s00432-013-1467-4.
    • (2013) J. Cancer Res. Clin. Oncol , vol.139 , Issue.9 , pp. 1489-1498
    • Chantzi, N.I.1    Tiniakos, D.G.2    Palaiologou, M.3    Goutas, N.4    Filippidis, T.5    Vassilaros, S.D.6
  • 27
    • 84901338598 scopus 로고    scopus 로고
    • Estrogen receptor β2 is inversely correlated with Ki-67 in hyperplastic and noninvasive neoplastic breast lesions
    • Chantzi N.I., Palaiologou M., Stylianidou A., Goutas N., Vassilaros S., Kourea H.P., et al. Estrogen receptor β2 is inversely correlated with Ki-67 in hyperplastic and noninvasive neoplastic breast lesions. J. Cancer Res. Clin. Oncol 2014, 140(6):1057-1066. 10.1007/s00432-014-1652-0.
    • (2014) J. Cancer Res. Clin. Oncol , vol.140 , Issue.6 , pp. 1057-1066
    • Chantzi, N.I.1    Palaiologou, M.2    Stylianidou, A.3    Goutas, N.4    Vassilaros, S.5    Kourea, H.P.6
  • 29
    • 0032896905 scopus 로고    scopus 로고
    • Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer
    • Harvey J.M., Clark G.M., Osborne C.K., Allred D.C. Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer. J. Clin. Oncol 1999, 17(5):1474-1481.
    • (1999) J. Clin. Oncol , vol.17 , Issue.5 , pp. 1474-1481
    • Harvey, J.M.1    Clark, G.M.2    Osborne, C.K.3    Allred, D.C.4
  • 30
    • 0026072872 scopus 로고
    • Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up
    • Elston C.W., Ellis I.O. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 1991, 19(5):403-410. 10.1046/j.1365-2559.2002.14892.x.
    • (1991) Histopathology , vol.19 , Issue.5 , pp. 403-410
    • Elston, C.W.1    Ellis, I.O.2
  • 31
    • 33748743807 scopus 로고    scopus 로고
    • Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells
    • Chang E.C., Frasor J., Komm B., Katzenellenbogen B.S. Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells. Endocrinology 2006, 147(10):4831-4842. doi:. http://dx.doi.org/10.1210/en.2006-0563.
    • (2006) Endocrinology , vol.147 , Issue.10 , pp. 4831-4842
    • Chang, E.C.1    Frasor, J.2    Komm, B.3    Katzenellenbogen, B.S.4
  • 32
    • 33746908103 scopus 로고    scopus 로고
    • Gene expression preferentially regulated by tamoxifen in breast cancer cells and correlations with clinical outcome
    • Frasor J., Chang E.C., Komm B., Lin C.Y., Vega V.B., Liu E.T., et al. Gene expression preferentially regulated by tamoxifen in breast cancer cells and correlations with clinical outcome. Cancer Res 2006, 66(14):7334-7340. 10.1158/0008-5472.CAN-05-4269.
    • (2006) Cancer Res , vol.66 , Issue.14 , pp. 7334-7340
    • Frasor, J.1    Chang, E.C.2    Komm, B.3    Lin, C.Y.4    Vega, V.B.5    Liu, E.T.6
  • 33
    • 84906938980 scopus 로고    scopus 로고
    • Oestrogen receptors β1 and βcx have divergent roles in breast cancer survival and lymph node metastasis
    • Rosin G., de Boniface J., Karthik G.M., Frisell J., Bergh J., Hartman J. Oestrogen receptors β1 and βcx have divergent roles in breast cancer survival and lymph node metastasis. Br. J. Cancer 2014, 111(5):918-926. 10.1038/bjc.2014.398.
    • (2014) Br. J. Cancer , vol.111 , Issue.5 , pp. 918-926
    • Rosin, G.1    de Boniface, J.2    Karthik, G.M.3    Frisell, J.4    Bergh, J.5    Hartman, J.6


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