메뉴 건너뛰기




Volumn 35, Issue 1, 2015, Pages 198-206

Alpha-1-antitrypsin deficiency: From genoma to liver disease. PiZ mouse as model for the development of liver pathology in human

Author keywords

AAT globules hepatocellular carcinoma; Alpha 1 antitrypsin deficiency; Dedifferentiated cells; Transgenic mouse

Indexed keywords

ALBUMIN; ALPHA 1 ANTITRYPSIN; ALPHA FETOPROTEIN; GENOMIC DNA; GLUCOSE; GLUCOSE 6 PHOSPHATE; HYALIN; MESSENGER RNA; PREALBUMIN; TYROSINE AMINOTRANSFERASE; BIOLOGICAL MARKER; PRIMER DNA; SERUM ALBUMIN;

EID: 84921060278     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12504     Document Type: Article
Times cited : (16)

References (31)
  • 1
    • 0024423930 scopus 로고
    • Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins
    • Huber R, Carrell RW. Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins. Biochemistry 1989; 28: 8951-66.
    • (1989) Biochemistry , vol.28 , pp. 8951-8966
    • Huber, R.1    Carrell, R.W.2
  • 2
    • 79959703757 scopus 로고    scopus 로고
    • Z α-1 antitrypsin deficiency and the endoplasmic reticulum stress response
    • Greene CM, McElvaney NG. Z α-1 antitrypsin deficiency and the endoplasmic reticulum stress response. World J Gastrointest Pharmacol Ther 2010; 1: 94-101.
    • (2010) World J Gastrointest Pharmacol Ther , vol.1 , pp. 94-101
    • Greene, C.M.1    McElvaney, N.G.2
  • 3
    • 0025350658 scopus 로고
    • Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy
    • Crystal RG. Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy. J Clin Invest 1990; 85: 1343-52.
    • (1990) J Clin Invest , vol.85 , pp. 1343-1352
    • Crystal, R.G.1
  • 4
    • 0030949205 scopus 로고    scopus 로고
    • Molecular basis, clinical consequences and diagnosis of alpha-1-antitrypsin deficiency
    • Norman MR, Mowat AP, Hutchinson DCS. Molecular basis, clinical consequences and diagnosis of alpha-1-antitrypsin deficiency. Ann Clin Biochem 1997; 34: 230-46.
    • (1997) Ann Clin Biochem , vol.34 , pp. 230-246
    • Norman, M.R.1    Mowat, A.P.2    Hutchinson, D.C.S.3
  • 5
    • 2642680855 scopus 로고    scopus 로고
    • α1-antitrypsin deficiency: memorandum from a WHO meeting
    • World Health Organization Meeting. α1-antitrypsin deficiency: memorandum from a WHO meeting. Bull World Health Organ 1997; 75: 397-415.
    • (1997) Bull World Health Organ , vol.75 , pp. 397-415
  • 6
    • 0029083915 scopus 로고
    • The liver in adolescents with alpha 1-antitrypsin deficiency
    • Sveger T, Eriksson S. The liver in adolescents with alpha 1-antitrypsin deficiency. Hepatology 1995; 22: 514-7.
    • (1995) Hepatology , vol.22 , pp. 514-517
    • Sveger, T.1    Eriksson, S.2
  • 7
    • 33748062353 scopus 로고    scopus 로고
    • Pathogenesis of chronic liver injury and hepatocellular carcinoma in alpha-1-antitrypsin deficiency
    • Review.
    • Perlmutter DH. Pathogenesis of chronic liver injury and hepatocellular carcinoma in alpha-1-antitrypsin deficiency. Pediatr Res 2006; 60: 233-8. Review.
    • (2006) Pediatr Res , vol.60 , pp. 233-238
    • Perlmutter, D.H.1
  • 8
    • 0023091532 scopus 로고
    • Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice
    • Sifers RN, Carlson JA, Clift SM, et al. Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice. Nucleic Acids Res 1987; 15: 1459-75.
    • (1987) Nucleic Acids Res , vol.15 , pp. 1459-1475
    • Sifers, R.N.1    Carlson, J.A.2    Clift, S.M.3
  • 9
    • 78149280472 scopus 로고    scopus 로고
    • Hepatic progenitor cell proliferation and liver injury in a-1-antitrypsin deficiency
    • Brunt EM, Blomenkamp K, Ahmed M, et al. Hepatic progenitor cell proliferation and liver injury in a-1-antitrypsin deficiency. JPGN 2010; 51: 626-30.
    • (2010) JPGN , vol.51 , pp. 626-630
    • Brunt, E.M.1    Blomenkamp, K.2    Ahmed, M.3
  • 10
    • 0024547734 scopus 로고
    • Accumulation of PiZ alpha 1-antitrypsin causes liver damage in transgenic mice
    • Carlson JA, Rogers BB, Sifers RN, et al. Accumulation of PiZ alpha 1-antitrypsin causes liver damage in transgenic mice. J Clin Invest 1989; 83: 1183-90.
    • (1989) J Clin Invest , vol.83 , pp. 1183-1190
    • Carlson, J.A.1    Rogers, B.B.2    Sifers, R.N.3
  • 11
    • 1842532017 scopus 로고    scopus 로고
    • Analyses of hepatocellular proliferation in a mouse model of alpha-1-antitrypsin deficiency
    • Rudnick DA, Liao Y, An JK, et al. Analyses of hepatocellular proliferation in a mouse model of alpha-1-antitrypsin deficiency. Hepatology 2004; 39: 1048-55.
    • (2004) Hepatology , vol.39 , pp. 1048-1055
    • Rudnick, D.A.1    Liao, Y.2    An, J.K.3
  • 12
    • 11244346111 scopus 로고    scopus 로고
    • Quantitative isolation of alphalAT mutant Z protein polymers from human and mouse livers and the effect of heat
    • An JK, Blomenkamp K, Lindblad D, Teckman JH. Quantitative isolation of alphalAT mutant Z protein polymers from human and mouse livers and the effect of heat. Hepatology 2005; 41: 160-7.
    • (2005) Hepatology , vol.41 , pp. 160-167
    • An, J.K.1    Blomenkamp, K.2    Lindblad, D.3    Teckman, J.H.4
  • 13
    • 36348957434 scopus 로고    scopus 로고
    • Alpha-1-antitrypsin mutant Z protein content in individual hepatocytes correlates with cell death in a mouse model
    • Lindblad D, Blomenkamp K, Teckman J. Alpha-1-antitrypsin mutant Z protein content in individual hepatocytes correlates with cell death in a mouse model. Hepatology 2007; 46: 1228-35.
    • (2007) Hepatology , vol.46 , pp. 1228-1235
    • Lindblad, D.1    Blomenkamp, K.2    Teckman, J.3
  • 14
    • 79551604651 scopus 로고    scopus 로고
    • Alpha-1-antitrypsin deficiency: importance of proteasomal and autophagic degradative pathways in disposal of liver disease-associated protein aggregates
    • Perlmutter DH. Alpha-1-antitrypsin deficiency: importance of proteasomal and autophagic degradative pathways in disposal of liver disease-associated protein aggregates. Annu Rev Med 2011; 62: 333-45.
    • (2011) Annu Rev Med , vol.62 , pp. 333-345
    • Perlmutter, D.H.1
  • 15
    • 79751488721 scopus 로고    scopus 로고
    • Proliferative and nonproliferative lesions of the rat and mouse hepatobiliary system
    • Thoolen B, Maronpot RR, Harada T, et al. Proliferative and nonproliferative lesions of the rat and mouse hepatobiliary system. Toxicol Pathol 2010; 38(7 Suppl.): 5S-81S.
    • (2010) Toxicol Pathol , vol.38 , Issue.7 , pp. 5S-81S
    • Thoolen, B.1    Maronpot, R.R.2    Harada, T.3
  • 16
    • 79955922341 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 deficient mice are protected from angiotensin II-induced fibrosis
    • Beier JI, Kaiser JP, Guo L, Martínez-Maldonado M, Arteel GE. Plasminogen activator inhibitor-1 deficient mice are protected from angiotensin II-induced fibrosis. Arch Biochem Biophys 2011; 510: 19-26.
    • (2011) Arch Biochem Biophys , vol.510 , pp. 19-26
    • Beier, J.I.1    Kaiser, J.P.2    Guo, L.3    Martínez-Maldonado, M.4    Arteel, G.E.5
  • 17
    • 74949106388 scopus 로고    scopus 로고
    • Differentiation of mouse embryonic stem cells into hepatocytes induced by a combination of cytokines and sodium butyrate
    • Zhou M, Li P, Tan L, et al. Differentiation of mouse embryonic stem cells into hepatocytes induced by a combination of cytokines and sodium butyrate. J Cell Biochem 2010; 109: 606-14.
    • (2010) J Cell Biochem , vol.109 , pp. 606-614
    • Zhou, M.1    Li, P.2    Tan, L.3
  • 18
    • 0028053044 scopus 로고
    • Hepatocarcinogenesis is the sequel to hepatitis in Z#2 alpha 1-antitrypsin transgenic mice: histopathological and DNA ploidy studies
    • Geller SA, Nichols WS, Kim S, et al. Hepatocarcinogenesis is the sequel to hepatitis in Z#2 alpha 1-antitrypsin transgenic mice: histopathological and DNA ploidy studies. Hepatology 1994; 19: 389-97.
    • (1994) Hepatology , vol.19 , pp. 389-397
    • Geller, S.A.1    Nichols, W.S.2    Kim, S.3
  • 19
    • 0021194415 scopus 로고
    • Alpha-1-antitrypsin (AAT) and its stimulation in the liver of PiMZ phenotype individuals. A "recruitment-secretory block" ("R-SB") phenomenon
    • Callea F, Fevery J, Massi G, et al. Alpha-1-antitrypsin (AAT) and its stimulation in the liver of PiMZ phenotype individuals. A "recruitment-secretory block" ("R-SB") phenomenon. Liver 1984; 4: 325-37.
    • (1984) Liver , vol.4 , pp. 325-337
    • Callea, F.1    Fevery, J.2    Massi, G.3
  • 20
    • 0034659888 scopus 로고    scopus 로고
    • Is heterozygous alpha-1-antitrypsin deficiency type PIZ a risk factor for primary liver carcinoma?
    • Zhou H, Ortiz-Pallardó ME, Ko Y, Fischer HP. Is heterozygous alpha-1-antitrypsin deficiency type PIZ a risk factor for primary liver carcinoma? Cancer 2000; 88: 2668-76.
    • (2000) Cancer , vol.88 , pp. 2668-2676
    • Zhou, H.1    Ortiz-Pallardó, M.E.2    Ko, Y.3    Fischer, H.P.4
  • 21
    • 73349093737 scopus 로고    scopus 로고
    • Z and Malton-1-antitrypsin deficiency-associated hepatocellular carcinoma: a genetic study
    • Francalanci P, Santorelli FM, Saccani S, et al. Z and Malton-1-antitrypsin deficiency-associated hepatocellular carcinoma: a genetic study. Liver Int 2009; 29: 1593-6.
    • (2009) Liver Int , vol.29 , pp. 1593-1596
    • Francalanci, P.1    Santorelli, F.M.2    Saccani, S.3
  • 22
    • 0028146998 scopus 로고
    • Self-induced correction of the genetic defect in tyrosinemia type I
    • Kvittingen EA, Rootwelt H, Berger R, Brandtzaeg P. Self-induced correction of the genetic defect in tyrosinemia type I. J Clin Invest 1994; 94: 1657-61.
    • (1994) J Clin Invest , vol.94 , pp. 1657-1661
    • Kvittingen, E.A.1    Rootwelt, H.2    Berger, R.3    Brandtzaeg, P.4
  • 23
    • 24144496018 scopus 로고    scopus 로고
    • Alpha-1-antitrypsin deficiency: a new paradigm for hepatocellular carcinoma in genetic liver disease
    • Rudnick DA, Perlmutter DH. Alpha-1-antitrypsin deficiency: a new paradigm for hepatocellular carcinoma in genetic liver disease. Hepatology 2005; 42: 514-21.
    • (2005) Hepatology , vol.42 , pp. 514-521
    • Rudnick, D.A.1    Perlmutter, D.H.2
  • 24
    • 77958603127 scopus 로고    scopus 로고
    • The digestive system II: the hepatobiliary system
    • Turton J. and Hooson J., eds. Taylor and Francis, London
    • Evans JG, Lake BG. The digestive system II: the hepatobiliary system. In: Turton J. and Hooson J., eds. Target Organ Pathology: A Basic Text. Taylor and Francis, London, 1998; 61-97.
    • (1998) Target Organ Pathology: A Basic Text , pp. 61-97
    • Evans, J.G.1    Lake, B.G.2
  • 25
    • 77954374752 scopus 로고    scopus 로고
    • Characteristics of hepatocellular carcinoma in a murine model of alpha-1-antitrypsin deficiency
    • Marcus NY, Brunt EM, Blomenkamp K, et al. Characteristics of hepatocellular carcinoma in a murine model of alpha-1-antitrypsin deficiency. Hepatol Res 2010; 40: 641-53.
    • (2010) Hepatol Res , vol.40 , pp. 641-653
    • Marcus, N.Y.1    Brunt, E.M.2    Blomenkamp, K.3
  • 26
    • 0024355293 scopus 로고
    • Focal impairment of growth in hepatocellular neoplasms of C57BL/6 mice: a possible explanation for the strain's resistance to hepatocarcinogenesis
    • Kakizoe S, Goldfarb S, Pugh TD. Focal impairment of growth in hepatocellular neoplasms of C57BL/6 mice: a possible explanation for the strain's resistance to hepatocarcinogenesis. Cancer Res 1989; 49: 3985-9.
    • (1989) Cancer Res , vol.49 , pp. 3985-3989
    • Kakizoe, S.1    Goldfarb, S.2    Pugh, T.D.3
  • 27
    • 64149125603 scopus 로고    scopus 로고
    • Stem and progenitor cells for liver repopulation: can we standardise the process from bench to bedside?
    • Sancho-Bru P, Najimi M, Caruso M, et al. Stem and progenitor cells for liver repopulation: can we standardise the process from bench to bedside? Gut 2009; 58: 594-603.
    • (2009) Gut , vol.58 , pp. 594-603
    • Sancho-Bru, P.1    Najimi, M.2    Caruso, M.3
  • 28
    • 0037255302 scopus 로고    scopus 로고
    • Significance of hepatic preneoplasia in risk identification and early detection of neoplasia
    • Bannasch P, Haertel T, Su Q. Significance of hepatic preneoplasia in risk identification and early detection of neoplasia. Toxicol Pathol 2003; 31: 134-9.
    • (2003) Toxicol Pathol , vol.31 , pp. 134-139
    • Bannasch, P.1    Haertel, T.2    Su, Q.3
  • 29
    • 0019796059 scopus 로고
    • Vinyl chloride-induced hepatic lesions in man and rodents. A comparison
    • Popper H, Maltoni C, Selikoff IJ. Vinyl chloride-induced hepatic lesions in man and rodents. A comparison. Liver 1981; 1: 7-20.
    • (1981) Liver , vol.1 , pp. 7-20
    • Popper, H.1    Maltoni, C.2    Selikoff, I.J.3
  • 30
    • 0029848724 scopus 로고    scopus 로고
    • Malignant hepatic tumours associated with previous exposure to Thorotrast: four cases
    • Lee FI, Tharakan J, Vasudev KS, Isaacs PE. Malignant hepatic tumours associated with previous exposure to Thorotrast: four cases. Eur J Gastroenterol Hepatol 1996; 8: 1121-4.
    • (1996) Eur J Gastroenterol Hepatol , vol.8 , pp. 1121-1124
    • Lee, F.I.1    Tharakan, J.2    Vasudev, K.S.3    Isaacs, P.E.4
  • 31
    • 0037135563 scopus 로고    scopus 로고
    • Detection of circulating and endothelial cell polymers of Z and wild type alpha 1-antitrypsin by a monoclonal antibody
    • Janciauskiene S, Dominaitiene R, Sternby NH, Piitulainen E, Eriksson S. Detection of circulating and endothelial cell polymers of Z and wild type alpha 1-antitrypsin by a monoclonal antibody. J Biol Chem 2002; 277: 26540-6.
    • (2002) J Biol Chem , vol.277 , pp. 26540-26546
    • Janciauskiene, S.1    Dominaitiene, R.2    Sternby, N.H.3    Piitulainen, E.4    Eriksson, S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.