Specific incorporation of an artificial nucleotide opposite a mutagenic DNA adduct by a DNA polymerase

Journal of the American Chemical Society

Volumn 137, Issue 1, 2015, Pages 30-33

  Wyss, Laura A ^a   Nilforoushan, Arman ^a   Eichenseher, Fritz ^a   Suter, Ursina ^a   Blatter, Nina ^b   Marx, Andreas ^b   Sturla, Shana J ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF KONSTANZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; NUCLEOTIDES; POLYMERS;

BENZIMIDAZOLES; DNA MODIFICATION; DNA POLYMERASE; DNA SYNTHESISS; NUCLEOTIDE ANALOGUES; PRODUCT FORMATION; STEADY-STATE KINETICS; TRANSLESION DNA SYNTHESIS;

DNA;

6 O BENZYLGUANINE; BENZIMIDAZOLE DERIVED 2' DEOXYNUCLEOSIDE 5' O TRIPHOSPHATE; DEOXYADENOSINE TRIPHOSPHATE; DEOXYCYTIDINE TRIPHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; DNA A; DNA POLYMERASE; NUCLEOSIDE DERIVATIVE; NUCLEOTIDE DERIVATIVE; PARATHION; THYMIDINE TRIPHOSPHATE; UNCLASSIFIED DRUG; DNA ADDUCT; DNA DIRECTED DNA POLYMERASE; NUCLEOTIDE;

ARTICLE; CATALYSIS; DNA ADDUCT; DNA ALKYLATION; DNA SEQUENCE; DNA SYNTHESIS; DNA TEMPLATE; GENE AMPLIFICATION; HYDROGEN BOND; STEADY STATE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM;

DNA ADDUCTS; DNA-DIRECTED DNA POLYMERASE; MOLECULAR STRUCTURE; NUCLEOTIDES;

EID: 84921047275     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja5100542     Document Type: Article

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