Nipple-Sparing Mastectomy in BRCA1/2 Mutation Carriers: An Interim Analysis and Review of the Literature

Annals of Surgical Oncology

Volumn 22, Issue 2, 2015, Pages 370-376

  Yao, Katharine ^a,c   Liederbach, Erik ^a   Tang, Rong ^b   Lei, Lan ^b   Czechura, Tomasz ^a   Sisco, Mark ^a,c   Howard, Michael ^a,c   Hulick, Peter J ^a   Winchester, David J ^a,c   Coopey, Suzanne B ^b   Smith, Barbara L ^b  

^a NORTHSHORE UNIVERSITY HEALTHSYSTEM   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN;

ADULT; AGED; ARTICLE; BREAST AREOLA; BREAST CANCER; CANCER PATIENT; CANCER RECURRENCE; CANCER SURGERY; CANCER THERAPY; CARCINOMA IN SITU; FEMALE; FOLLOW UP; GENE MUTATION; GRAFT FAILURE; GRAFT NECROSIS; HETEROZYGOTE; HUMAN; INCIDENTAL CANCER; INTRADUCTAL CARCINOMA; LONG TERM CARE; MAJOR CLINICAL STUDY; MASTECTOMY; MEDICAL RECORD REVIEW; NEOPLASM; NIPPLE AREOLAR COMPLEX; NIPPLE SPARING MASTECTOMY; POSTOPERATIVE COMPLICATION; PRIMARY TUMOR; RISK REDUCTION; TREATMENT OUTCOME; BREAST NEOPLASMS; GENETICS; MIDDLE AGED; MUTATION; NIPPLE; PATHOLOGY; PROCEDURES; RETROSPECTIVE STUDY; TUMOR RECURRENCE; TUMOR SUPPRESSOR GENE;

ADULT; AGED; BREAST NEOPLASMS; FEMALE; GENES, BRCA1; GENES, BRCA2; HETEROZYGOTE; HUMANS; MASTECTOMY; MIDDLE AGED; MUTATION; NEOPLASM RECURRENCE, LOCAL; NIPPLES; RETROSPECTIVE STUDIES;

EID: 84921027455     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-014-3883-3     Document Type: Article

References (31)

1. de Alcantara Filho P, Capko D, Barry JM, et al. Nipple-sparing mastectomy for breast cancer and risk reducing surgery: the Memorial Sloan-Kettering Cancer Center experience. Ann Surg Oncol. 2011;18:3117–3122.
2. Wagner JL, Fearmonti R, Hunt KK, et al. Prospective evaluation of the nipple-areola complex sparing mastectomy for risk reduction and for early stage breast cancer. Ann Surg Oncol. 2012;19:1137–1144.
3. Jensen JA, Orringer JS, Giuliano AE. Nipple sparing mastectomy in 99 patients with a mean follow up of 5 years. Ann Surg Oncol. 2011;18:1665–1670.
4. Harness JK, Vetter TS, Salibian AH. Areola and nipple-areola-sparing mastectomy for breast cancer treatment and risk reduction: report of an initial experience in a community hospital setting. Ann Surg Oncol. 2011;18:917–922.
5. Crowe JP, Patrick RJ, Yetman RJ, Djohan R. Nipple sparing mastectomy update: one hundred forty nine procedures and clinical outcomes. Arch Surg. 2008; 146:1106–1110.
6. Warren Peled A, Foster RD, Stover AC, et al. Outcomes after total skin-sparing mastectomy and immediate reconstruction in 657 breasts. Ann Surg Oncol. 2012; 19:3402–3409.
7. Gerber B, Krause A, Dieterich M, Kundt G, Reimer T. The oncological safety of skin sparing mastectomy with conservation of the nipple-areola complex and autologous reconstruction: an extended follow up study. Ann Surg Oncol. 2009;249:461–468.
8. Kim HJ, Park EH, Lim WS, et al. Nipple areola skin sparing mastectomy with immediate transverse rectus abdominis musculocutaneous flap reconstruction is an oncologically safe procedure. Ann Surg. 2010;251:493–498.
9. Benediktsson KP, Perbeck L. Survival in breast cancer after nipple sparing subcutaneous mastectomy with immediate reconstruction with implants: a prospective trial with 13 years median follow-up in 216 patients. Eur J Surg Oncol. 2008;34:143–148.
10. Kurian AW, Sigal BM, Plevritis SK. Survival analysis of cancer risk reduction strategies for BRCA 1 and 2 mutation carriers. J Clin Oncol. 2010;28:222–231.
11. Antoniou A, Pharoah P, Narod S, et al. Average risks of breast and ovarian cancer associated with BRCA 1 and BRCA 2 mutations detected in case series unselected for family history: a combined analysis of 22 studies. Am J Hum Genet. 2003;72:1117–1130.
12. Pierce LJ, Levin AM, Rebbeck TR, et al. Ten year multi-institutional results of breast conserving surgery and radiotherapy in BRCA1 and 2 associated stage I and II breast cancer. J Clin Oncol. 2006;24:2437–2443.
13. Metcalfe K, Lynch HT, Ghadirian P, et al. Contralateral breast cancer in BRCA1 and BRCA2 mutation carriers. J Clin Oncol. 2004;22:2328–2335.
14. Hartman LC, Schaid DJ, Woods JE, et al. Efficacy of bilateral prophylactic mastectomy in women with a family history of breast cancer. N Engl J Med. 1999;340:77–84.
15. Meijers-Heijboer H, van Geel B, van Putten WL, et al. Breast cancer after prophylactic bilateral mastectomy in women with BRCA1 or BRCA2 mutation. N Engl J Med. 2001;345:159–164.
16. Rebbeck TR, Friebel T, Lynch HT, et al. Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: the PROSE study group. J Clin Oncol. 2004;22:1055–1062.
17. Heemskerk-Gerritsen, Brekelmans CT, Menke-Pluymers MB, et al. Prophylactic mastectomy in BRCA 1/2 mutation carriers and women at risk of hereditary breast cancer: long-term experiences at the Rotterdam Family Cancer Clinic. Ann Surg Oncol. 2007;14:3335–3344.
18. Reynolds C, Davidson JA, Lindor NM, et al. Prophylactic and therapeutic mastectomy in BRCA mutation carriers: can the nipple be preserved? Ann Surg Oncol. 2011;18:3102–3109.
19. Peled AW, Irwin CS, Hwang ES, Ewing CA, Alvarado M, Esserman LJ. Total skin-sparing mastectomy in BRCA mutation carriers. Ann Surg Oncol. 2014;21:37–41.
20. Colwell AS, Tessler O, Lin AM, et al. Breast reconstruction following nipple-sparing mastectomy: predictors of complications, reconstruction outcomes, and 5-year trends. Plast Reconstr Surg. 2014;133:496–506.
21. Spear SL, Willey SC, Feldman ED, et al. Nipple-sparing mastectomy for prophylactic and therapeutic indications. Plast Reconstr Surg.2011;128:1005–1014.
22. Algaithy ZK, Petit JY, Lohsiriwat V, et al. Nipple sparing mastectomy: can we predict the factors predisposing to necrosis? Eur J Surg Oncol. 2012;38:125–129.
23. Hartman LC, SellersTA, Schaid DJ, et al. Efficacy of bilateral prophylactic mastectomy in BRCA1 and BRCA2 gene mutation carriers. J Natl Cancer Inst. 2001;93:1633–1637.
24. Domchek SM, Friebel TM, Singer CF, et al. Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality. JAMA. 2010;304:967–975.
25. Sacchini V, Pinotti JA, Barros AC, et al. Nipple-sparing mastectomy for breast cancer and risk reduction: oncologic or technical problem? J Am Coll Surg. 2006;203:704–714.
26. Billar JA, Dueck AC, Gray RJ, Wasif N, Pockaj BA. Preoperative predictors of nipple-areola complex involvement for patients undergoing mastectomy for breast cancer. Ann Surg Oncol. 2011;18:3123–3128.
27. Stanec Z, Zic R, Budi S, et al. Skin and nipple-areola complex sparing mastectomy in breast cancer patients: 15-year experience. Ann Plast Surg. Epub 25 Dec 2013.
28. Brachtel EF, Rusby JE, Michaelson JS, et al. Occult nipple involvement in breast cancer: clinicopathologic findings in 316 consecutive mastectomy specimens. J Clin Oncol. 2009;27:4948–4954.
29. Simmons RM, Fish SK, Gayle L, et al. Local and distant recurrence rates in skin-sparing mastectomies compared with non-skin-sparing mastectomies. Ann Surg Oncol. 1999;6:676–681.
30. Petit JY, Veronesi U, Rey P, et al. Nipple-sparing mastectomy: risk of nipple-areolar recurrences in a series of 579 cases. Breast Cancer Res Treat. 2009;114:97–101.
31. Coopey SB, Tang R, Lei L, et al. Increasing eligibility for nipple-sparing mastectomy. Ann Surg Oncol. 2013;20:3218–3222.