Prenatal physical activity and diet composition affect the expression of nutrient transporters and mTOR signaling molecules in the human placenta

Placenta

Volumn 36, Issue 2, 2015, Pages 204-212

  Brett, K E ^a,b   Ferraro, Z M ^c   Holcik, M ^a,d   Adamo, K B ^a,b,d  

^a CHILDREN S HOSPITAL OF EASTERN ONTARIO   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

^d UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Diet; mTOR; Nutrient transport; Physical activity; Placenta

Indexed keywords

AKT1 PROTEIN; AMINO ACID TRANSPORTER; AMP ACTIVATED PROTEIN KINASE ALPHA 1 CATALYTIC SUBUNIT; AMP ACTIVATED PROTEIN KINASE BETA 1 NON CATALYTIC SUBUNIT; FATTY ACID BINDING PROTEIN 3; FATTY ACID BINDING PROTEIN 4; FATTY ACID BINDING PROTEIN 5; FATTY ACID TRANSPORT PROTEIN 2; FATTY ACID TRANSPORTER; FATTY ACID TRANSPORTER 4; GLUCOSE TRANSPORTER; GLUCOSE TRANSPORTER 1; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INITIATION FACTOR 4B; INITIATION FACTOR 4E BINDING PROTEIN 1; INSULIN; INSULIN RECEPTOR SUBSTRATE 1; LIPOPROTEIN LIPASE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; PROTEIN S6; RIBOSOMAL PROTEIN S6 KINASE 70 KDA POLYPEPTIDE 1; S6 KINASE; SODIUM COUPLED NEUTRAL AMINO ACID TRANSPORTER 2; SODIUM COUPLED NEUTRAL AMINO ACID TRANSPORTER 4; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR; TUBERIN; TUBEROUS SCLEROSIS 1 PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ACCELEROMETRY; ADULT; ARTICLE; CALORIC INTAKE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; HUMAN; HUMAN TISSUE; MATERNAL NUTRITION; NEWBORN; NUTRITIONAL ASSESSMENT; PHYSICAL ACTIVITY; PLACENTA; POLYMERASE CHAIN REACTION; PRENATAL PERIOD; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SUGAR INTAKE; DIET; ENERGY METABOLISM; FOOD; GENETICS; MALE; METABOLISM; MOTOR ACTIVITY; PHYSIOLOGY; PREGNANCY; PRENATAL CARE; PRENATAL EXPOSURE; TRANSPORT AT THE CELLULAR LEVEL;

ADULT; BIOLOGICAL TRANSPORT; DIET; ENERGY METABOLISM; FEMALE; FOOD; HUMANS; INFANT, NEWBORN; MALE; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; MEMBRANE TRANSPORT PROTEINS; MOTOR ACTIVITY; PLACENTA; PREGNANCY; PRENATAL CARE; PRENATAL EXPOSURE DELAYED EFFECTS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84920986037     PISSN: 01434004     EISSN: 15323102     Source Type: Journal    
DOI: 10.1016/j.placenta.2014.11.015     Document Type: Article

References (49)

1. S.L. Nascimento, F.G. Surita, and J.G. Cecatti Physical exercise during pregnancy: a systematic review Curr Opin Obstet Gynecol 24 6 2012 387 394
2. Z.M. Ferraro, L. Gaudet, and K.B. Adamo The potential impact of physical activity during pregnancy on maternal and neonatal outcomes Obstet Gynecol Surv 67 2 2012 99 110
3. R. Artal, and M. O'Toole Guidelines of the American College of Obstetricians and Gynecologists for exercise during pregnancy and the postpartum period Br J Sports Med 37 1 2003 6 12
4. G.A. Davies, L.A. Wolfe, M.L. Mottola, and C. Mackinnon Joint SOGC/CSEP clinical practice guideline: exercise in pregnancy and the postpartum period Can J Appl Physiol 28 3 2003 330 341
5. L.A. Wolfe, and G.A. Davies Canadian guidelines for exercise in pregnancy Clin Obstet Gynecol 46 2 2003 488 495
6. A.N. Sferruzzi-Perri, O.R. Vaughan, M. Haro, W.N. Cooper, B. Musial, and M. Charalambous An obesogenic diet during mouse pregnancy modifies maternal nutrient partitioning and the fetal growth trajectory FASEB J 27 10 2013 3928 3937
7. V. King, N. Hibbert, J.R. Seckl, J.E. Norman, and A.J. Drake The effects of an obesogenic diet during pregnancy on fetal growth and placental gene expression are gestation dependent Placenta 34 11 2013 1087 1090
8. H.N. Jones, L.A. Woollett, N. Barbour, P.D. Prasad, T.L. Powell, and T. Jansson High-fat diet before and during pregnancy causes marked up-regulation of placental nutrient transport and fetal overgrowth in C57/BL6 mice FASEB J 23 1 2009 271 278
9. R.M. Lewis, S.L. Greenwood, J.K. Cleal, S.R. Crozier, L. Verrall, and H.M. Inskip Maternal muscle mass may influence system A activity in human placenta Placenta 31 5 2010 418 422
10. K.B. Adamo, Z.M. Ferraro, and K.E. Brett Can we modify the intrauterine environment to halt the intergenerational cycle of obesity? Int J Environ Res Public Health 9 4 2012 1263 1307
11. Canadian Society for Exercise Physiology Physical activity readiness medical examination (PARmed-X) for pregnancy 2013 [Ref Type: Pamphlet]
12. D.S. Downs, G.C. LeMasurier, and J.M. Dinallo Baby steps: pedometer-determined and self-reported leisure-time exercise behaviors of pregnant women J Phys Act Health 6 1 2009 63 72
13. C.L. Harrison, R.G. Thompson, H.J. Teede, and C.B. Lombard Measuring physical activity during pregnancy Int J Behav Nutr Phys Act 8 2011 19
14. P. Breithaupt, K.B. Adamo, and R.C. Colley The HALO submaximal treadmill protocol to measure cardiorespiratory fitness in obese children and youth: a proof of principle study Appl Physiol Nutr Metab 37 2 2012 308 314
15. National Cancer Institute Automated self-administered 24-Hour recall (ASA24) 2011 Bethesda, MD. 6-1-2014. Ref Type: Internet Communication
16. R.C. Colley, S.C. Gorber, and M.S. Tremblay Quality control and data reduction procedures for accelerometry-derived measures of physical activity Health Rep 21 1 2010 63 69
17. R.C. Colley, D. Garriguet, I. Janssen, C.L. Craig, J. Clarke, and M.S. Tremblay Physical activity of Canadian children and youth: accelerometer results from the 2007 to 2009 Canadian Health Measures Survey Health Rep 22 1 2011 15 23
18. R.C. Colley, D. Garriguet, I. Janssen, C.L. Craig, J. Clarke, and M.S. Tremblay Physical activity of Canadian adults: accelerometer results from the 2007 to 2009 Canadian Health Measures Survey Health Rep 22 1 2011 7 14
19. S.L. Wong, R. Colley, G.S. Connor, and M. Tremblay Actical accelerometer sedentary activity thresholds for adults J Phys Act Health 8 4 2011 587 591
20. M.S. Tremblay, D.E. Warburton, I. Janssen, D.H. Paterson, A.E. Latimer, and R.E. Rhodes New Canadian physical activity guidelines Appl Physiol Nutr Metab 36 1 2011 36 46
21. J.K. Cleal, P. Day, M.A. Hanson, and R.M. Lewis Measurement of housekeeping genes in human placenta Placenta 30 11 2009 1002 1003
22. S. Drewlo, K. Levytska, and J. Kingdom Revisiting the housekeeping genes of human placental development and insufficiency syndromes Placenta 33 11 2012 952 954
23. K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 4 2001 402 408
24. M. Juhl, J. Olsen, P. Anderson, E. Nohr, and A. Anderson Physical exercise during pregnancy and fetal growth measures: a study within the Danish National Birth Cohort Am J Obstetrics Gynecol 202 1 2010 e1 e8
25. Z.M. Ferraro, N. Barrowman, D. Prud'homme, M. Walker, S.W. Wen, and M. Rodger Excessive gestational weight gain predicts large for gestational age neonates independent of maternal body mass index J Matern Fetal Neonatal Med 25 5 2012 538 542
26. D.S. Ludwig, and J. Currie The association between pregnancy weight gain and birthweight: a within-family comparison Lancet 376 9745 2010 984 990
27. C.S. Harrod, L. Chasan-Taber, R.M. Reynolds, T.E. Fingerlin, D.H. Glueck, and J.T. Brinton Physical activity in pregnancy and neonatal body composition: the healthy start study Obstet Gynecol 124 2 2014 257 264
28. P. Cunningham, and L. McDermott Long chain PUFA transport in human term placenta J Nutr 139 4 2009 636 639
29. J.F. Clapp III, and E. Capeless Neonatal morphometrics after endurance exercise during pregnancy Am J Obstetrics Gynecol 163 6 I 1990 1805 1811
30. M. Desforges, K.J. Mynett, R.L. Jones, S.L. Greenwood, M. Westwood, and C.P. Sibley The SNAT4 isoform of the system A amino acid transporter is functional in human placental microvillous plasma membrane J Physiol 587 Pt 1 2009 61 72
31. M. Desforges, S.L. Greenwood, J.D. Glazier, M. Westwood, and C.P. Sibley The contribution of SNAT1 to system A amino acid transporter activity in human placental trophoblast Biochem Biophys Res Commun 398 1 2010 130 134
32. D. Garriguet, and R.C. Colley A comparison of self-reported leisure-time physical activity and measured moderate-to-vigorous physical activity in adolescents and adults Health Rep 25 7 2014 3 11
33. S.A. Prince, K.B. Adamo, M.E. Hamel, J. Hardt, G.S. Connor, and M. Tremblay A comparison of direct versus self-report measures for assessing physical activity in adults: a systematic review Int J Behav Nutr Phys Act 5 2008 56
34. C. Chiesa, J.F. Osborn, C. Haass, F. Natale, M. Spinelli, and E. Scapillati Ghrelin, leptin, IGF-1, IGFBP-3, and insulin concentrations at birth: is there a relationship with fetal growth and neonatal anthropometry? Clin Chem 54 3 2008 550 558
35. S.A. Hopkins, J.C. Baldi, W.S. Cutfield, L. McCowan, and P.L. Hofman Exercise training in pregnancy reduces offspring size without changes in maternal insulin sensitivity J Clin Endocrinol Metab 95 5 2010 2080 2088
36. S.A. Hopkins, J.C. Baldi, W.S. Cutfield, L. McCowan, and P.L. Hofman Effects of exercise training on maternal hormonal changes in pregnancy Clin Endocrinol (Oxf) 74 4 2011 495 500
37. M. Laplante, and D.M. Sabatini mTOR signaling in growth control and disease Cell 149 2 2012 274 293
38. S. Roos, N. Jansson, I. Palmberg, K. Saljo, T.L. Powell, and T. Jansson Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth J Physiol 582 Pt 1 2007 449 459
39. S. Roos, Y. Kanai, P.D. Prasad, T.L. Powell, and T. Jansson Regulation of placental amino acid transporter activity by mammalian target of rapamycin Am J Physiol Cell Physiol 296 1 2009 C142 C150
40. X. Liu, R.R. Chhipa, S. Pooya, M. Wortman, S. Yachyshin, and L.M. Chow Discrete mechanisms of mTOR and cell cycle regulation by AMPK agonists independent of AMPK Proc Natl Acad Sci U S A 111 4 2014 E435 E444
41. J. Xu, J. Ji, and X.H. Yan Cross-talk between AMPK and mTOR in regulating energy balance Crit Rev Food Sci Nutr 52 5 2012 373 381
42. K. Forbes, and M. Westwood The IGF axis and placental function. A mini review Horm Res 69 3 2008 129 137
43. N.P. Illsley Glucose transporters in the human placenta Placenta 21 1 2000 14 22
44. T. Jansson, and T.L. Powell IFPA 2005 award in placentology lecture. Human placental transport in altered fetal growth: does the placenta function as a nutrient sensor? - A review Placenta 27 Suppl. A 2006 S91 S97
45. M. Colomiere, M. Permezel, C. Riley, G. Desoye, and M. Lappas Defective insulin signaling in placenta from pregnancies complicated by gestational diabetes mellitus Eur J Endocrinol 160 4 2009 567 578
46. H.N. Jones, T.L. Powell, and T. Jansson Regulation of placental nutrient transport-a review Placenta 28 8-9 2007 763 774
47. K. Ogura, M. Sakata, M. Yamaguchi, H. Kurachi, and Y. Murata High concentration of glucose decreases glucose transporter-1 expression in mouse placenta in vitro and in vivo J Endocrinol 160 3 1999 443 452
48. Health Canada Dietary reference intakes tables 2010 Government of Canada Canada
49. Y. Lin, Y. Zhuo, Z.F. Fang, L.Q. Che, and D. Wu Effect of maternal dietary energy types on placenta nutrient transporter gene expressions and intrauterine fetal growth in rats Nutrition 28 10 2012 1037 1043