A novel role for the zinc-finger transcription factor EGL-46 in the differentiation of Gas-sensing neurons in Caenorhabditis elegans

Genetics

Volumn 199, Issue 1, 2015, Pages 157-163

  Romanos, Teresa Rojo ^a   Petersen, Jakob Gramstrup ^a   Riveiro, Alba Redo ^a   Pocock, Roger ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE; GUANYLATE CYCLASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR EGL46; TRANSCRIPTION FACTOR SOX; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; CAENORHABDITIS ELEGANS PROTEIN; EGL-13 PROTEIN, C ELEGANS; EGL-46 PROTEIN, C ELEGANS; OXYGEN;

ADULT; ANIMAL EXPERIMENT; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; NEMATODE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; SENSORY NERVE CELL; ANIMAL; CHEMORECEPTOR CELL; DRUG EFFECTS; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; NERVOUS SYSTEM DEVELOPMENT;

CAENORHABDITIS ELEGANS; METAZOA;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CARBON DIOXIDE; CHEMORECEPTOR CELLS; GUANYLATE CYCLASE; NEUROGENESIS; OXYGEN; TRANSCRIPTION FACTORS;

EID: 84920883483     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.114.172049     Document Type: Article

References (25)

1. Bigelow, H., M. Doitsidou, S. Sarin, and O. Hobert, 2009 MAQGene: software to facilitate C. elegans mutant genome sequence analysis. Nat. Methods 6: 549.
2. Brandt, J. P., S. Aziz-Zaman, V. Juozaityte, L. A. Martinez-Velazquez, J. G. Petersen et al., 2012 A single gene target of an ETS-family transcription factor determines neuronal CO(2)-chemosensitivity. PLoS ONE 7: e34014.
3. Brenner, S., 1974 The genetics of Caenorhabditis elegans. Genetics 77: 71–94.
4. Bretscher, A. J., K. E. Busch, and M. de Bono, 2008 A carbon dioxide avoidance behavior is integrated with responses to ambientoxygen and food in Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 105: 8044–8049.
5. Cayirlioglu, P., I. G. Kadow, X. Zhan, K. Okamura, G. S. Suh et al., 2008 Hybrid neurons in a microRNA mutant are putative evolutionary intermediates in insect CO2 sensory systems. Science 319: 1256–1260.
6. Doitsidou, M., N. Flames, A. C. Lee, A. Boyanov, and O. Hobert, 2008 Automated screening for mutants affecting dopaminergicneuron specification in C. elegans. Nat. Methods 5: 869–872.
7. Doitsidou, M., R. J. Poole, S. Sarin, H. Bigelow, and O. Hobert, 2010 C. elegans mutant identification with a one-step wholegenome- sequencing and SNP mapping strategy. PLoS ONE 5: e15435.
8. Feng, G., P. Yi, Y. Yang, Y. Chai, D. Tian et al., 2013 Developmental stage-dependent transcriptional regulatory pathways control neuroblast lineage progression. Development 140: 3838–3847.
9. Flibotte, S., M. L. Edgley, I. Chaudhry, J. Taylor, S. E. Neil et al., 2010 Whole-genome profiling of mutagenesis in Caenorhabditis elegans. Genetics 185: 431–441.
10. Gramstrup Petersen, J., T. Rojo Romanos, V. Juozaityte, A. Redo Riveiro, I. Hums et al., 2013 EGL-13/SoxD specifies distinct O2 and CO2 sensory neuron fates in Caenorhabditis elegans. PLoS Genet. 9: e1003511.
11. Guillermin, M. L., M. L. Castelletto, and E. A. Hallem, 2011 Differentiation of carbon dioxide-sensing neurons in Caenorhabditis elegans requires the ETS-5 transcription factor. Genetics 189: 1327–1339.
12. Hallem, E. A., W. C. Spencer, R. D. McWhirter, G. Zeller, S. R. Henz et al., 2011 Receptor-type guanylate cyclase is required for carbon dioxide sensation by Caenorhabditis elegans. Proc. Natl. Acad. Sci. USA 108: 254–259.
13. Hartl, M., L. F. Loschek, D. Stephan, K. P. Siju, C. Knappmeyer et al., 2011 A new Prospero and microRNA-279 pathway restricts CO2 receptor neuron formation. J. Neurosci. 31: 15660–15673.
14. Hobert, O., 2002 PCR fusion-based approach to create reporter gene constructs for expression analysis in transgenic C. elegans. Biotechniques 32: 728–730.
15. Hobert, O., 2008 Regulatory logic of neuronal diversity: terminal selector genes and selector motifs. Proc. Natl. Acad. Sci. USA 105: 20067–20071.
16. Hobert, O., 2011 Regulation of terminal differentiation programs in the nervous system. Annu. Rev. Cell Dev. Biol. 27: 681–696.
17. Hobert, O., I. Carrera, and N. Stefanakis, 2010 The molecular and gene regulatory signature of a neuron. Trends Neurosci. 33: 435–445.
18. Mello, C. C., J. M. Kramer, D. Stinchcomb, and V. Ambros, 1991 Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 10: 3959–3970.
19. Ramot, D., B. E. Johnson, T. L. Berry, Jr., L. Carnell, and M. B. Goodman, 2008 The Parallel Worm Tracker: a platform for measuring average speed and drug-induced paralysis in nematodes. PLoS ONE 3: e2208.
20. Rosenbaum, J. N., A. Duggan, and J. Garcia-Anoveros, 2011 Insm1 promotes the transition of olfactory progenitors from apical and proliferative to basal, terminally dividing and neuronogenic. Neural Dev. 6: 6.
21. Sun, L., H. Wang, J.Hu, J. Han, H.Matsunami et al., 2009 Guanylyl cyclase-D in the olfactory CO2 neurons is activated by bicarbonate. Proc. Natl. Acad. Sci. USA 106: 2041–2046.
22. Tsunozaki, M., S. H. Chalasani, and C. I. Bargmann, 2008 A behavioral switch: cGMP and PKC signaling in olfactory neurons reverses odor preference in C. elegans. Neuron 59: 959–971.
23. Wang, J., H. T. Schwartz, and M. M. Barr, 2010 Functional specialization of sensory cilia by an RFX transcription factor isoform. Genetics 186: 1295–1307.
24. Wu, J., A. Duggan, and M. Chalfie, 2001 Inhibition of touch cell fate by egl-44 and egl-46 in C. elegans. Genes Dev. 15: 789–802.
25. Zimmer, M., J. M. Gray, N. Pokala, A. J. Chang, D. S. Karow et al., 2009 Neurons detect increases and decreases in oxygen levels using distinct guanylate cyclases. Neuron 61: 865–879.