메뉴 건너뛰기




Volumn 32, Issue 2, 2015, Pages

Sorafenib reverses resistance of gastric cancer to treatment by cisplatin through down-regulating MDR1 expression

Author keywords

Cell line; Drug resistance; MDR; Sorafenib; Stomach neoplasm

Indexed keywords

CISPLATIN; MITOGEN ACTIVATED PROTEIN KINASE; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN KINASE B; SORAFENIB; ABCB1 PROTEIN, HUMAN; ANTINEOPLASTIC AGENT; CARBANILAMIDE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN; NICOTINAMIDE;

EID: 84920837676     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-014-0470-1     Document Type: Article
Times cited : (16)

References (25)
  • 2
    • 51249090123 scopus 로고    scopus 로고
    • The regulation of extracellular signal-regulated kinase (ERK) in mammalian cells
    • COI: 1:CAS:528:DC%2BD1cXhtFaisb7E, PID: 18562239
    • Ramos JW. The regulation of extracellular signal-regulated kinase (ERK) in mammalian cells. Int J Biochem Cell Biol. 2008;40(12):2707–19.
    • (2008) Int J Biochem Cell Biol , vol.40 , Issue.12 , pp. 2707-2719
    • Ramos, J.W.1
  • 3
    • 34547209343 scopus 로고    scopus 로고
    • Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
    • COI: 1:CAS:528:DC%2BD2sXosFyksbk%3D, PID: 17126425
    • McCubrey JA, Steelman LS, Chappell WH, Abrams SL, Wong EW, Chang F, et al. Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance. Biochim Biophys Acta. 2007;1773(8):1263–84.
    • (2007) Biochim Biophys Acta , vol.1773 , Issue.8 , pp. 1263-1284
    • McCubrey, J.A.1    Steelman, L.S.2    Chappell, W.H.3    Abrams, S.L.4    Wong, E.W.5    Chang, F.6
  • 4
    • 38949183695 scopus 로고    scopus 로고
    • Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy
    • COI: 1:CAS:528:DC%2BD1cXhtVKisLY%3D, PID: 18223206
    • Friday BB, Adjei AA. Advances in targeting the Ras/Raf/MEK/Erk mitogen-activated protein kinase cascade with MEK inhibitors for cancer therapy. Clin Cancer Res. 2008;14(2):342–6.
    • (2008) Clin Cancer Res , vol.14 , Issue.2 , pp. 342-346
    • Friday, B.B.1    Adjei, A.A.2
  • 5
    • 76249095217 scopus 로고    scopus 로고
    • PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells
    • COI: 1:CAS:528:DC%2BC3cXht12rur4%3D, PID: 20103619
    • Yacoub A, Hamed HA, Allegood J, Mitchell C, Spiegel S, Lesniak MS, et al. PERK-dependent regulation of ceramide synthase 6 and thioredoxin play a key role in mda-7/IL-24-induced killing of primary human glioblastoma multiforme cells. Cancer Res. 2010;70:1120–9.
    • (2010) Cancer Res , vol.70 , pp. 1120-1129
    • Yacoub, A.1    Hamed, H.A.2    Allegood, J.3    Mitchell, C.4    Spiegel, S.5    Lesniak, M.S.6
  • 6
    • 41149155977 scopus 로고    scopus 로고
    • OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells
    • COI: 1:CAS:528:DC%2BD1cXjvFelsrs%3D, PID: 18182481
    • Park MA, Yacoub A, Rahmani M, Zhang G, Hart L, Hagan MP, et al. OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells. Mol Pharmacol. 2008;73:1168–84.
    • (2008) Mol Pharmacol , vol.73 , pp. 1168-1184
    • Park, M.A.1    Yacoub, A.2    Rahmani, M.3    Zhang, G.4    Hart, L.5    Hagan, M.P.6
  • 7
    • 67650831206 scopus 로고    scopus 로고
    • Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms
    • COI: 1:CAS:528:DC%2BD1MXptlegsr4%3D, PID: 19483104
    • Walker T, Mitchell C, Park MA, Yacoub A, Graf M, Rahmani M, et al. Sorafenib and vorinostat kill colon cancer cells by CD95-dependent and -independent mechanisms. Mol Pharmacol. 2009;76:342–55.
    • (2009) Mol Pharmacol , vol.76 , pp. 342-355
    • Walker, T.1    Mitchell, C.2    Park, M.A.3    Yacoub, A.4    Graf, M.5    Rahmani, M.6
  • 8
    • 67650786255 scopus 로고    scopus 로고
    • BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing
    • COI: 1:CAS:528:DC%2BD1MXptlehu7c%3D, PID: 19483105
    • Martin AP, Park MA, Mitchell C, Walker T, Rahmani M, Thorburn A, et al. BCL-2 family inhibitors enhance histone deacetylase inhibitor and sorafenib lethality via autophagy and overcome blockade of the extrinsic pathway to facilitate killing. Mol Pharmacol. 2009;76:327–41.
    • (2009) Mol Pharmacol , vol.76 , pp. 327-341
    • Martin, A.P.1    Park, M.A.2    Mitchell, C.3    Walker, T.4    Rahmani, M.5    Thorburn, A.6
  • 9
    • 77955474688 scopus 로고    scopus 로고
    • Sorafenib activates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells
    • COI: 1:CAS:528:DC%2BC3cXpvVOjs7s%3D, PID: 20682655
    • Park MA, Reinehr R, Häussinger D, Voelkel-Johnson C, Ogretmen B, Yacoub A, et al. Sorafenib activates CD95 and promotes autophagy and cell death via Src family kinases in gastrointestinal tumor cells. Mol Cancer Ther. 2010;9:2220–31.
    • (2010) Mol Cancer Ther , vol.9 , pp. 2220-2231
    • Park, M.A.1    Reinehr, R.2    Häussinger, D.3    Voelkel-Johnson, C.4    Ogretmen, B.5    Yacoub, A.6
  • 11
    • 84864869645 scopus 로고    scopus 로고
    • New use for an old drug:inhibiting ABCG2 with sorafenib
    • COI: 1:CAS:528:DC%2BC38XhtFOisL3J, PID: 22593228
    • Wei Y, Ma Y, Zhao Q, Ren Z, Li Y, Hou T, et al. New use for an old drug:inhibiting ABCG2 with sorafenib. Mol Cancer Ther. 2012;11:1693–702.
    • (2012) Mol Cancer Ther , vol.11 , pp. 1693-1702
    • Wei, Y.1    Ma, Y.2    Zhao, Q.3    Ren, Z.4    Li, Y.5    Hou, T.6
  • 12
    • 70349669267 scopus 로고    scopus 로고
    • Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters
    • COI: 1:CAS:528:DC%2BD1MXhtF2lur7J, PID: 19773380
    • Hu S, Chen Z, Franke R, Orwick S, Zhao M, Rudek MA, et al. Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters. Clin Cancer Res. 2009;15:6062–9.
    • (2009) Clin Cancer Res , vol.15 , pp. 6062-6069
    • Hu, S.1    Chen, Z.2    Franke, R.3    Orwick, S.4    Zhao, M.5    Rudek, M.A.6
  • 13
    • 77953679525 scopus 로고    scopus 로고
    • Tyrosine kinase inhibitors gefitinib, lapatinib and sorafenib induce rapid functional alterations in breast cancer cells
    • COI: 1:CAS:528:DC%2BC3cXns1Snsbk%3D, PID: 20384581
    • Carloni S, Fabbri F, Brigliadori G, Ulivi P, Silvestrini R, Amadori D, et al. Tyrosine kinase inhibitors gefitinib, lapatinib and sorafenib induce rapid functional alterations in breast cancer cells. Curr Cancer Drug Targets. 2010;10:422–31.
    • (2010) Curr Cancer Drug Targets , vol.10 , pp. 422-431
    • Carloni, S.1    Fabbri, F.2    Brigliadori, G.3    Ulivi, P.4    Silvestrini, R.5    Amadori, D.6
  • 15
    • 33745318524 scopus 로고    scopus 로고
    • Reversing multidrug resistance by RNA interference through the suppression of MDR1 gene in human hepatoma cells
    • COI: 1:CAS:528:DC%2BD28XnsFWkt7s%3D, PID: 16733848
    • Chen XP, Wang Q, Guan J, Huang ZY, Zhang WG, Zhang BX. Reversing multidrug resistance by RNA interference through the suppression of MDR1 gene in human hepatoma cells. World J Gastroenterol. 2006;12(21):3332–7.
    • (2006) World J Gastroenterol , vol.12 , Issue.21 , pp. 3332-3337
    • Chen, X.P.1    Wang, Q.2    Guan, J.3    Huang, Z.Y.4    Zhang, W.G.5    Zhang, B.X.6
  • 16
    • 84903127246 scopus 로고    scopus 로고
    • Associations of polymorphisms in DNA repair genes and MDR1 gene with chemotherapy response and survival of non-small cell lung cancer
    • PID: 24933103
    • Du Y, Su T, Zhao L, Tan X, Chang W, Zhang H, Cao G. Associations of polymorphisms in DNA repair genes and MDR1 gene with chemotherapy response and survival of non-small cell lung cancer. PLoS One. 2014;9(6):e99843.
    • (2014) PLoS One , vol.9 , Issue.6 , pp. e99843
    • Du, Y.1    Su, T.2    Zhao, L.3    Tan, X.4    Chang, W.5    Zhang, H.6    Cao, G.7
  • 17
    • 84902532046 scopus 로고    scopus 로고
    • HIF-1α inhibition reverses multidrug resistance in colon cancer cells via downregulation of MDR1/P-glycoprotein
    • PID: 24901645
    • Chen J, Ding Z, Peng Y, Pan F, Li J, Zou L, Zhang Y, Liang H. HIF-1α inhibition reverses multidrug resistance in colon cancer cells via downregulation of MDR1/P-glycoprotein. PLoS One. 2014;9(6):e98882.
    • (2014) PLoS One , vol.9 , Issue.6 , pp. e98882
    • Chen, J.1    Ding, Z.2    Peng, Y.3    Pan, F.4    Li, J.5    Zou, L.6    Zhang, Y.7    Liang, H.8
  • 18
    • 78650736659 scopus 로고    scopus 로고
    • Overexpression of sorcin results in multidrug resistance in gastric cancer cells with up-regulation of P-gp
    • COI: 1:CAS:528:DC%2BC3MXhsl2iu70%3D, PID: 21109982
    • He Q, Zhang G, Hou D, et al. Overexpression of sorcin results in multidrug resistance in gastric cancer cells with up-regulation of P-gp. Oncol Rep. 2011;25(1):237–43.
    • (2011) Oncol Rep , vol.25 , Issue.1 , pp. 237-243
    • He, Q.1    Zhang, G.2    Hou, D.3
  • 19
    • 42649122978 scopus 로고    scopus 로고
    • Expression of multidrug-resistance-related proteins P-glycoprotein, glutathione-S-transferases, topoisomerase-II and lung resistance protein in primary gastric cardiac adenocarcinoma
    • COI: 1:CAS:528:DC%2BD1cXlt1aht74%3D, PID: 18443954
    • Shi H, Lu D, Shu Y, et al. Expression of multidrug-resistance-related proteins P-glycoprotein, glutathione-S-transferases, topoisomerase-II and lung resistance protein in primary gastric cardiac adenocarcinoma. Cancer Invest. 2008;26(4):344–51.
    • (2008) Cancer Invest , vol.26 , Issue.4 , pp. 344-351
    • Shi, H.1    Lu, D.2    Shu, Y.3
  • 20
    • 0346256782 scopus 로고    scopus 로고
    • Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2)
    • COI: 1:CAS:528:DC%2BD3sXptFOqs74%3D, PID: 12946267
    • Woehlecke H, Pohl A, Alder-Baerens N, et al. Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2). Biochem J. 2003;376(Pt 2):489–95.
    • (2003) Biochem J , vol.376 , pp. 489-495
    • Woehlecke, H.1    Pohl, A.2    Alder-Baerens, N.3
  • 21
    • 0034493847 scopus 로고    scopus 로고
    • Expression of multidrug resistance-related markers in gastric cancer
    • COI: 1:STN:280:DC%2BD3M7is1emsQ%3D%3D, PID: 11205224
    • Fan K, Fan D, Cheng LF, et al. Expression of multidrug resistance-related markers in gastric cancer. Anticancer Res. 2000;20(6C):4809–14.
    • (2000) Anticancer Res , vol.20 , Issue.6C , pp. 4809-4814
    • Fan, K.1    Fan, D.2    Cheng, L.F.3
  • 22
    • 84856524126 scopus 로고    scopus 로고
    • Phase I dose-finding study of sorafenib in combination with capecitabine and cisplatin as a first-line treatment in patients with advanced gastric cancer
    • COI: 1:CAS:528:DC%2BC38XotVWgsA%3D%3D, PID: 20839031
    • Kim C, Lee JL, Choi YH, et al. Phase I dose-finding study of sorafenib in combination with capecitabine and cisplatin as a first-line treatment in patients with advanced gastric cancer. Invest New Drugs. 2012;30(1):306–15.
    • (2012) Invest New Drugs , vol.30 , Issue.1 , pp. 306-315
    • Kim, C.1    Lee, J.L.2    Choi, Y.H.3
  • 23
    • 77954574658 scopus 로고    scopus 로고
    • Phase II study of sorafenib in combination with docetaxel and cisplatin in the treatment of metastatic or advanced gastric and gastroesophageal junction adenocarcinoma: ECOG 5203
    • COI: 1:CAS:528:DC%2BC3cXptlajtb4%3D, PID: 20458043
    • Sun W, Powell M, O’Dwyer PJ, et al. Phase II study of sorafenib in combination with docetaxel and cisplatin in the treatment of metastatic or advanced gastric and gastroesophageal junction adenocarcinoma: ECOG 5203. J Clin Oncol. 2010;28(18):2947–51.
    • (2010) J Clin Oncol , vol.28 , Issue.18 , pp. 2947-2951
    • Sun, W.1    Powell, M.2    O’Dwyer, P.J.3
  • 24
    • 82955241985 scopus 로고    scopus 로고
    • Phase II study of sunitinib as second-line treatment for advanced gastric cancer
    • Bang YJ, Kang YK, Kang WK, et al. Phase II study of sunitinib as second-line treatment for advanced gastric cancer. Invest New Drugs. 2011;29(6):L1449–58.
    • (2011) Invest New Drugs , vol.29 , Issue.6 , pp. L1449-L1458
    • Bang, Y.J.1    Kang, Y.K.2    Kang, W.K.3
  • 25
    • 79958803154 scopus 로고    scopus 로고
    • An open-label, multicentre biomarker-oriented AIO phase II trial of sunitinib for patients with chemo-refractory advanced gastric cancer
    • COI: 1:CAS:528:DC%2BC3MXnsleju7s%3D, PID: 21561763
    • Moehler M, Mueller A, Hartmann JT, et al. An open-label, multicentre biomarker-oriented AIO phase II trial of sunitinib for patients with chemo-refractory advanced gastric cancer. Eur J Cancer. 2011;47(10):1511–20.
    • (2011) Eur J Cancer , vol.47 , Issue.10 , pp. 1511-1520
    • Moehler, M.1    Mueller, A.2    Hartmann, J.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.