Quantifying the real life risk profile of inhaled corticosteroids in COPD by record linkage analysis

Respiratory Research

Volumn 15, Issue 1, 2014, Pages

  Flynn, Rob W ^a   MacDonald, Thomas M ^a   Hapca, Adrian ^a   MacKenzie, Isla S ^a   Schembri, Stuart ^b  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b NINEWELLS HOSPITAL   (United Kingdom)

Author keywords

Cataract; COPD; Diabetes; Inhaled steroids; Pneumonia

Indexed keywords

CORTICOSTEROID;

AGED; ARTICLE; CATARACT; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; DATA ANALYSIS; DETERIORATION; DIABETES MELLITUS; DRUG USE; FEMALE; FOLLOW UP; FRACTURE; HAZARD RATIO; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTIVARIATE ANALYSIS; PNEUMONIA; PRESCRIPTION; PROPORTIONAL HAZARDS MODEL; RISK ASSESSMENT; CHEMICALLY INDUCED; COHORT ANALYSIS; FACTUAL DATABASE; FRACTURES, BONE; INHALATIONAL DRUG ADMINISTRATION; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RISK FACTOR; STATISTICS AND NUMERICAL DATA;

ADMINISTRATION, INHALATION; ADRENAL CORTEX HORMONES; AGED; COHORT STUDIES; DATABASES, FACTUAL; DIABETES MELLITUS; FEMALE; FRACTURES, BONE; HUMANS; MALE; MIDDLE AGED; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RISK FACTORS;

EID: 84920815453     PISSN: 14659921     EISSN: 1465993X     Source Type: Journal    
DOI: 10.1186/s12931-014-0141-y     Document Type: Article

References (32)

1. Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, Abraham J, Adair T, Aggarwal R, Ahn SY, Alvarado M, Anderson HR, Anderson LM, Andrews KG, Atkinson C, Baddour LM, Barker-Collo S, Bartels DH, Bell ML, Benjamin EJ, Bennett D, Bhalla K, Bikbov B, Bin Abdulhak A, Birbeck G, Blyth F, Bolliger I, Boufous S, Bucello C, Burch M, et al: Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012, 380: 2095-2128. 10.1016/S0140-6736(12)61728-0.
2. Chronic Obstructive Pulmonary Disease: National clinical guideline on management of adults with chronic obstructive pulmonary disease in primary and secondary care. NICE guideline 12. Thorax. 2004, 59 (I): 1-232.
3. Godtfredsen NS, Lam TH, Hansel TT, Leon ME, Gray N, Dresler C, Burns DM, Prescott E, Vestbo J: COPD-related morbidity and mortality after smoking cessation: status of the evidence. ERJ. 2008, 32: 844-853. 10.1183/09031936.00160007.
4. Long-term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema. Lancet. 1981, 1: 681-686.
5. Calverley PM, Anderson JA, Celli B, Ferguson GT, Jenkins C, Jones PW, Yates JC, Vestbo J: Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease. N Engl J Med. 2007, 356: 775-789. 10.1056/NEJMoa063070.
6. British National Formulary. 2014, BMJ Group and Pharmaceutical Press, London
7. Kew KM, Seniukovich A: Inhaled steroids and risk of pneumonia for chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2014, 3:
8. Garbe E, Suissa S, LeLorier J: Association of inhaled corticosteroid use with cataract extraction in elderly patients. JAMA. 1998, 280: 539-543. 10.1001/jama.280.6.539.
9. Lipworth BJ: Systemic adverse effects of inhaled corticosteroid therapy: a systematic review and meta-analysis. Arch Intern Med. 1999, 159: 941-955. 10.1001/archinte.159.9.941.
10. Kelly HW, Nelson HS: Potential adverse effects of the inhaled corticosteroids. J Allergy Clin Immunol. 2003, 112: 469-478. 10.1016/S0091-6749(03)01870-0.
11. Suissa S, Kezouh A, Ernst P: Inhaled corticosteroids and the Risks of Diabetes Onset and Progression. Am J Med. 2010, 123: 1001-1006. 10.1016/j.amjmed.2010.06.019.
12. Scottish Medicines Consortium. SMC No. (953/14; 2014 [ONLINE] Available at:. [Accessed 03 November 14]., [ www.scottishmedicines.org.uk/SMC_Advice/Advice/953_14_fluticasone_furoate_vilanterol_Relvar/fluticasone_furoate_vilanterol_Relvar_Ellipta ]
13. Scottish medicine consortium. SMC No. (4 50/08); 2008 [ONLINE] Available at:. [Accessed 03 November 14], [ www.scottishmedicines.org.uk/files/salmeterol_fluticasone_inhaler__Seretide_500_Accuhaler_FINAL_Feb_2008_for_website_amended_13_03_08.pdf ]
14. Short PM, Lipworth SI, Elder DH, Schembri S, Lipworth BJ: Effect of β blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study. BMJ. 2011, 342: d2549-10.1136/bmj.d2549.
15. Wei L, Parkinson J, MacDonald TM: The Tayside Medicines Monitoring unit (MEMO). Pharmacoepidemiology. Edited by: Strom BL. 2005, John Wiley and Sons, Chichester, 323-336. 4
16. Sheng X, Murphy MJ, MacDonald TM, Schembri S, Simpson W, Winter J, Winter JH, Wei L: Effect of statins on total cholesterol concentrations, cardiovascular morbidity, and all-cause mortality in chronic obstructive pulmonary disease: a population-based cohort study. Clin Ther. 2012, 34: 374-384. 10.1016/j.clinthera.2011.12.014.
17. Morris AD, Boyle DI, MacAlpine R, Emslie-Smith A, Jung RT, Newton RW, MacDonald TM: The diabetes audit and research in Tayside Scotland (DARTS) study: electronic record linkage to create a diabetes register. DARTS/MEMO Collaboration. Br Med J. 1997, 315: 524-528. 10.1136/bmj.315.7107.524.
18. International classification of diseases, related health problems. 1992, World Health Organization, Geneva
19. Tabular List of the Classification of Surgical Operations and Procedures Fourth Revision. 1990, Her Majesty's Stationery Office, London
20. Suissa S, Patenaude V, Lapi F, Ernst P: Inhaled corticosteroids in COPD and the risk of serious pneumonia. Thorax. 2013, 68: 1029-1036. 10.1136/thoraxjnl-2012-202872.
21. McMahon M, Gerich J, Rizza R: Effects of glucocorticoids on carbohydrate metabolism. Diabetes Metab Rev. 1988, 4: 17-30. 10.1002/dmr.5610040105.
22. Dendukuri N, Blais L, LeLorier J: Inhaled corticosteroids and the risk of diabetes among the elderly. Br J Clin Pharmacol. 2002, 54: 59-64. 10.1046/j.1365-2125.2002.01610.x.
23. Blackburn D, Hux J, Mamdani M: Quantification of the risk of corticosteroid-induced diabetes mellitus among the elderly. J Gen Intern Med. 2002, 17: 717-720. 10.1046/j.1525-1497.2002.10649.x.
24. Caughey GE, Preiss AK, Vitry AI, Gilbert AL, Roughead EE: Comorbid diabetes and COPD: impact of corticosteroid use on diabetes complications. Diabetes Care. 2013, 36: 3009-3014. 10.2337/dc12-2197.
25. O'Byrne PM, Rennard S, Gerstein H, Radner F, Peterson S, Lindberg B, Carlsson LG, Sin DD: Risk of new onset diabetes mellitus in patients with asthma or COPD taking inhaled corticosteroids. Respir Med. 2012, 106: 1487-1493. 10.1016/j.rmed.2012.07.011.
26. Janson C, Larsson K, Lisspers KH, Ställberg B, Stratelis G, Goike H, Jörgensen L, Johansson G: Pneumonia and pneumonia related mortality in patients with COPD treated with fixed combinations of inhaled corticosteroid and long acting β2 agonist: observational matched cohort study (PATHOS). BMJ. 2013, 346: f3306-10.1136/bmj.f3306.
27. Ek A, Larsson K, Siljerud S, Palmberg L: Fluticasone and budesonide inhibit cytokine release in human lung epithelial cells and alveolar macrophages. Allergy. 1999, 54: 691-699. 10.1034/j.1398-9995.1999.00087.x.
28. Ferguson GT, Calverley PM, Anderson JA, Jenkins CR, Jones PW, Willits LR, Yates JC, Vestbo J, Celli B: Prevalence and progression of osteoporosis in patients with COPD: results from the TOwards a Revolution in COPD Health study. Chest. 2009, 136: 1456-1465. 10.1378/chest.08-3016.
29. Yang IA, Clarke MS, Sim EH, Fong KM: Inhaled corticosteroids for stable chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2012, 11: 7-CD002991
30. Dransfield MT, Bourbeau J, Jones PW, Hanania NA, Mahler DA, Vestbo J, Wachtel A, Martinez FJ, Barnhart F, Sanford L, Lettis S, Crim C, Calverley PM: Once-daily inhaled fluticasone furoate and vilanterol versus vilanterol only for prevention of exacerbations of COPD: two replicate double-blind, parallel-group, randomised controlled trials. Lancet Respir Med. 2013, 1: 210-223. 10.1016/S2213-2600(13)70040-7.
31. Vestbo J, Sørensen T, Lange P, Brix A, Torre P, Viskum K: Long-term effect of inhaled budesonide in mild and moderate chronic obstructive pulmonary disease: a randomised controlled trial. Lancet. 1999, 353: 1819-1823. 10.1016/S0140-6736(98)10019-3.
32. Jebrak G, Initiatives B: COPD routine management in France: are guidelines used in clinical practice?. Rev Mal Respir. 2010, 27: 11-18. 10.1016/j.rmr.2009.08.002.