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Volumn 39, Issue 1, 2015, Pages 149-159

Evaluation of intervertebral disc regeneration with implantation of bone marrow mesenchymal stem cells (BMSCs) using quantitative T2 mapping: a study in rabbits

Author keywords

Aggrecan; Bone marrow mesenchymal stem cells; Intervertebral disc degeneration; Quantitative analysis; T2 mapping; Type II collagen

Indexed keywords

AGGRECAN; COLLAGEN TYPE 2; GLYCOSAMINOGLYCAN; PHOSPHATE BUFFERED SALINE;

EID: 84920808480     PISSN: 03412695     EISSN: 14325195     Source Type: Journal    
DOI: 10.1007/s00264-014-2481-0     Document Type: Article
Times cited : (41)

References (48)
  • 1
    • 37349041034 scopus 로고    scopus 로고
    • A systematic review of low back pain cost of illness studies in the United States and internationally
    • PID: 18164449
    • Dagenais S, Caro J, Haldeman S (2008) A systematic review of low back pain cost of illness studies in the United States and internationally. Spine J 8:8–20
    • (2008) Spine J , vol.8 , pp. 8-20
    • Dagenais, S.1    Caro, J.2    Haldeman, S.3
  • 2
    • 57049102269 scopus 로고    scopus 로고
    • Future perspectives of cell-based therapy for intervertebral disc disease
    • PID: 19005704
    • Sakai D (2008) Future perspectives of cell-based therapy for intervertebral disc disease. Eur Spine J 17(Suppl 4):452–458
    • (2008) Eur Spine J , vol.17 , pp. 452-458
    • Sakai, D.1
  • 3
    • 0036201942 scopus 로고    scopus 로고
    • Intervertebral disc degeneration adjacent to a lumbar fusion. An experimental rabbit model
    • COI: 1:STN:280:DC%2BD387ovFKlsA%3D%3D, PID: 11922374
    • Phillips FM, Reuben J, Wetzel FT (2002) Intervertebral disc degeneration adjacent to a lumbar fusion. An experimental rabbit model. J Bone Joint Surg Br 84:289–294
    • (2002) J Bone Joint Surg Br , vol.84 , pp. 289-294
    • Phillips, F.M.1    Reuben, J.2    Wetzel, F.T.3
  • 4
    • 84863775266 scopus 로고    scopus 로고
    • Higher BMP receptor expression and BMP-2-induced osteogenic differentiation in tendon-derived stem cells compared with bone-marrow-derived mesenchymal stem cells
    • PID: 22134708
    • Rui YF, Lui PP, Lee YW, Chan KM (2012) Higher BMP receptor expression and BMP-2-induced osteogenic differentiation in tendon-derived stem cells compared with bone-marrow-derived mesenchymal stem cells. Int Orthop 36:1099–1107
    • (2012) Int Orthop , vol.36 , pp. 1099-1107
    • Rui, Y.F.1    Lui, P.P.2    Lee, Y.W.3    Chan, K.M.4
  • 5
    • 84858795202 scopus 로고    scopus 로고
    • Osteogenic differentiation is synergistically influenced by osteoinductive treatment and direct cell-cell contact between murine osteoblasts and mesenchymal stem cells
    • PID: 21567150
    • Tsai MT, Lin DJ, Huang S, Lin HT, Chang WH (2012) Osteogenic differentiation is synergistically influenced by osteoinductive treatment and direct cell-cell contact between murine osteoblasts and mesenchymal stem cells. Int Orthop 36:199–205
    • (2012) Int Orthop , vol.36 , pp. 199-205
    • Tsai, M.T.1    Lin, D.J.2    Huang, S.3    Lin, H.T.4    Chang, W.H.5
  • 7
    • 84920856086 scopus 로고    scopus 로고
    • Translational medicine in orthopaedics
    • Qin L (2013) Translational medicine in orthopaedics. J Orthop Transl 1:3–5
    • (2013) J Orthop Transl , vol.1 , pp. 3-5
    • Qin, L.1
  • 8
    • 84862855802 scopus 로고    scopus 로고
    • Ex vivo observation of human intervertebral disc tissue and cells isolated from degenerated intervertebral discs
    • PID: 22395304
    • Ciapetti G, Granchi D, Devescovi V, Leonardi E, Greggi T, Di Silvestre M, Baldini N (2012) Ex vivo observation of human intervertebral disc tissue and cells isolated from degenerated intervertebral discs. Eur Spine J 21(Suppl 1):S10–S19
    • (2012) Eur Spine J , vol.21 , pp. S10-S19
    • Ciapetti, G.1    Granchi, D.2    Devescovi, V.3    Leonardi, E.4    Greggi, T.5    Di Silvestre, M.6    Baldini, N.7
  • 9
    • 33644973923 scopus 로고    scopus 로고
    • The involvement of aggrecan polymorphism in degeneration of human intervertebral disc and articular cartilage
    • COI: 1:CAS:528:DC%2BD28XislSgtL8%3D, PID: 16425147, discussion 7
    • Roughley P, Martens D, Rantakokko J, Alini M, Mwale F, Antoniou J (2006) The involvement of aggrecan polymorphism in degeneration of human intervertebral disc and articular cartilage. Eur Cell Mater 11:1–7, discussion 7
    • (2006) Eur Cell Mater , vol.11 , pp. 1-7
    • Roughley, P.1    Martens, D.2    Rantakokko, J.3    Alini, M.4    Mwale, F.5    Antoniou, J.6
  • 11
    • 0037708391 scopus 로고    scopus 로고
    • Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potential therapeutic model for disc degeneration
    • COI: 1:CAS:528:DC%2BD3sXktlOgtL0%3D, PID: 12809782
    • Sakai D, Mochida J, Yamamoto Y, Nomura T, Okuma M, Nishimura K, Nakai T, Ando K, Hotta T (2003) Transplantation of mesenchymal stem cells embedded in Atelocollagen gel to the intervertebral disc: a potential therapeutic model for disc degeneration. Biomaterials 24:3531–3541
    • (2003) Biomaterials , vol.24 , pp. 3531-3541
    • Sakai, D.1    Mochida, J.2    Yamamoto, Y.3    Nomura, T.4    Okuma, M.5    Nishimura, K.6    Nakai, T.7    Ando, K.8    Hotta, T.9
  • 12
    • 27644541907 scopus 로고    scopus 로고
    • Differentiation of mesenchymal stem cells transplanted to a rabbit degenerative disc model: potential and limitations for stem cell therapy in disc regeneration
    • Sakai D, Mochida J, Iwashina T, Watanabe T, Nakai T, Ando K, Hotta T (2005) Differentiation of mesenchymal stem cells transplanted to a rabbit degenerative disc model: potential and limitations for stem cell therapy in disc regeneration. Spine (Phila Pa 1976) 30:2379–2387
    • (2005) Spine (Phila Pa 1976) , vol.30 , pp. 2379-2387
    • Sakai, D.1    Mochida, J.2    Iwashina, T.3    Watanabe, T.4    Nakai, T.5    Ando, K.6    Hotta, T.7
  • 13
    • 0025727489 scopus 로고
    • Disc degeneration in magnetic resonance imaging. A comparative biochemical, histologic, and radiologic study in cadaver spines
    • COI: 1:STN:280:DyaK3MzitVajsA%3D%3D
    • Tertti M, Paajanen H, Laato M, Aho H, Komu M, Kormano M (1991) Disc degeneration in magnetic resonance imaging. A comparative biochemical, histologic, and radiologic study in cadaver spines. Spine (Phila Pa 1976) 16:629–634
    • (1991) Spine (Phila Pa 1976) , vol.16 , pp. 629-634
    • Tertti, M.1    Paajanen, H.2    Laato, M.3    Aho, H.4    Komu, M.5    Kormano, M.6
  • 14
    • 0031723670 scopus 로고    scopus 로고
    • Quantitative magnetic resonance imaging in the assessment of degenerative disc disease
    • COI: 1:STN:280:DyaK1M%2FlsVGksg%3D%3D, PID: 9840835
    • Antoniou J, Pike GB, Steffen T, Baramki H, Poole AR, Aebi M, Alini M (1998) Quantitative magnetic resonance imaging in the assessment of degenerative disc disease. Magn Reson Med 40:900–907
    • (1998) Magn Reson Med , vol.40 , pp. 900-907
    • Antoniou, J.1    Pike, G.B.2    Steffen, T.3    Baramki, H.4    Poole, A.R.5    Aebi, M.6    Alini, M.7
  • 15
    • 0033982913 scopus 로고    scopus 로고
    • A model of unloaded human intervertebral disk based on NMR relaxation
    • COI: 1:STN:280:DC%2BD3c7gs1CmsQ%3D%3D, PID: 10642729
    • Nightingale T, MacKay A, Pearce RH, Whittall KP, Flak B (2000) A model of unloaded human intervertebral disk based on NMR relaxation. Magn Reson Med 43:34–44
    • (2000) Magn Reson Med , vol.43 , pp. 34-44
    • Nightingale, T.1    MacKay, A.2    Pearce, R.H.3    Whittall, K.P.4    Flak, B.5
  • 16
    • 65549124972 scopus 로고    scopus 로고
    • T2 relaxation times of intervertebral disc tissue correlated with water content and proteoglycan content
    • Marinelli NL, Haughton VM, Muñoz A, Anderson PA (2009) T2 relaxation times of intervertebral disc tissue correlated with water content and proteoglycan content. Spine (Phila Pa 1976) 34:520–524
    • (2009) Spine (Phila Pa 1976) , vol.34 , pp. 520-524
    • Marinelli, N.L.1    Haughton, V.M.2    Muñoz, A.3    Anderson, P.A.4
  • 17
    • 80054040699 scopus 로고    scopus 로고
    • MR imaging assessment of lumbar intervertebral disk degeneration and age-related changes: apparent diffusion coefficient versus T2 quantitation
    • COI: 1:STN:280:DC%2BC3MfpsFWrsg%3D%3D, PID: 21799044
    • Niu G, Yang J, Wang R, Dang S, Wu EX, Guo Y (2011) MR imaging assessment of lumbar intervertebral disk degeneration and age-related changes: apparent diffusion coefficient versus T2 quantitation. AJNR Am J Neuroradiol 32:1617–1623
    • (2011) AJNR Am J Neuroradiol , vol.32 , pp. 1617-1623
    • Niu, G.1    Yang, J.2    Wang, R.3    Dang, S.4    Wu, E.X.5    Guo, Y.6
  • 21
    • 3242781589 scopus 로고    scopus 로고
    • T2 relaxation time of cartilage at MR imaging: comparison with severity of knee osteoarthritis
    • PID: 15215540
    • Dunn TC, Lu Y, Jin H, Ries MD, Majumdar S (2004) T2 relaxation time of cartilage at MR imaging: comparison with severity of knee osteoarthritis. Radiology 232:592–598
    • (2004) Radiology , vol.232 , pp. 592-598
    • Dunn, T.C.1    Lu, Y.2    Jin, H.3    Ries, M.D.4    Majumdar, S.5
  • 22
    • 2942552147 scopus 로고    scopus 로고
    • T2 and T1rho MRI in articular cartilage systems
    • COI: 1:CAS:528:DC%2BD2cXivVemsbw%3D, PID: 15004791
    • Menezes NM, Gray ML, Hartke JR, Burstein D (2004) T2 and T1rho MRI in articular cartilage systems. Magn Reson Med 51:503–509
    • (2004) Magn Reson Med , vol.51 , pp. 503-509
    • Menezes, N.M.1    Gray, M.L.2    Hartke, J.R.3    Burstein, D.4
  • 23
    • 33745437684 scopus 로고    scopus 로고
    • Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue
    • COI: 1:CAS:528:DC%2BD28XhtFGhu7fJ, PID: 16410387
    • Kern S, Eichler H, Stoeve J, Klüter H, Bieback K (2006) Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells 24:1294–1301
    • (2006) Stem Cells , vol.24 , pp. 1294-1301
    • Kern, S.1    Eichler, H.2    Stoeve, J.3    Klüter, H.4    Bieback, K.5
  • 24
    • 12144281256 scopus 로고    scopus 로고
    • Quantitative analysis of gene expression in a rabbit model of intervertebral disc degeneration by real-time polymerase chain reaction
    • PID: 15653081
    • Sobajima S, Shimer AL, Chadderdon RC, Kompel JF, Kim JS, Gilbertson LG, Kang JD (2005) Quantitative analysis of gene expression in a rabbit model of intervertebral disc degeneration by real-time polymerase chain reaction. Spine J 5:14–23
    • (2005) Spine J , vol.5 , pp. 14-23
    • Sobajima, S.1    Shimer, A.L.2    Chadderdon, R.C.3    Kompel, J.F.4    Kim, J.S.5    Gilbertson, L.G.6    Kang, J.D.7
  • 25
    • 0031410873 scopus 로고    scopus 로고
    • Effects of chondroitinase ABC and chymopapain on spinal motion segment biomechanics. An in vivo biomechanical, radiologic, and histologic canine study
    • COI: 1:STN:280:DyaK2svisF2luw%3D%3D, discussion 1834–1825
    • Lu DS, Shono Y, Oda I, Abumi K, Kaneda K (1997) Effects of chondroitinase ABC and chymopapain on spinal motion segment biomechanics. An in vivo biomechanical, radiologic, and histologic canine study. Spine (Phila Pa 1976) 22:1828–1834, discussion 1834–1825
    • (1997) Spine (Phila Pa 1976) , vol.22 , pp. 1828-1834
    • Lu, D.S.1    Shono, Y.2    Oda, I.3    Abumi, K.4    Kaneda, K.5
  • 26
    • 33845404614 scopus 로고    scopus 로고
    • Morphologic comparison of cervical, thoracic, lumbar intervertebral discs of cynomolgus monkey (Macaca fascicularis)
    • PID: 16374650
    • Longo UG, Ripalda P, Denaro V, Forriol F (2006) Morphologic comparison of cervical, thoracic, lumbar intervertebral discs of cynomolgus monkey (Macaca fascicularis). Eur Spine J 15:1845–1851
    • (2006) Eur Spine J , vol.15 , pp. 1845-1851
    • Longo, U.G.1    Ripalda, P.2    Denaro, V.3    Forriol, F.4
  • 27
    • 34548176977 scopus 로고    scopus 로고
    • Changes in T2 relaxation times associated with maturation of the human intervertebral disk
    • COI: 1:STN:280:DC%2BD2svotFCqtQ%3D%3D, PID: 17698522
    • Krueger EC, Perry JO, Wu Y, Haughton VM (2007) Changes in T2 relaxation times associated with maturation of the human intervertebral disk. AJNR Am J Neuroradiol 28:1237–1241
    • (2007) AJNR Am J Neuroradiol , vol.28 , pp. 1237-1241
    • Krueger, E.C.1    Perry, J.O.2    Wu, Y.3    Haughton, V.M.4
  • 28
    • 70449133790 scopus 로고    scopus 로고
    • Mesenchymal stem cells arrest intervertebral disc degeneration through chondrocytic differentiation and stimulation of endogenous cells
    • COI: 1:CAS:528:DC%2BD1MXotF2qsrY%3D, PID: 19584814
    • Yang F, Leung VY, Luk KD, Chan D, Cheung KM (2009) Mesenchymal stem cells arrest intervertebral disc degeneration through chondrocytic differentiation and stimulation of endogenous cells. Mol Ther 17:1959–1966
    • (2009) Mol Ther , vol.17 , pp. 1959-1966
    • Yang, F.1    Leung, V.Y.2    Luk, K.D.3    Chan, D.4    Cheung, K.M.5
  • 29
    • 4444349673 scopus 로고    scopus 로고
    • Magnetic resonance imaging measurement of relaxation and water diffusion in the human lumbar intervertebral disc under compression in vitro
    • COI: 1:STN:280:DC%2BD3Mnks1Gisg%3D%3D
    • Chiu EJ, Newitt DC, Segal MR, Hu SS, Lotz JC, Majumdar S (2001) Magnetic resonance imaging measurement of relaxation and water diffusion in the human lumbar intervertebral disc under compression in vitro. Spine (Phila Pa 1976) 26:E437–E444
    • (2001) Spine (Phila Pa 1976) , vol.26 , pp. E437-E444
    • Chiu, E.J.1    Newitt, D.C.2    Segal, M.R.3    Hu, S.S.4    Lotz, J.C.5    Majumdar, S.6
  • 30
    • 84860442659 scopus 로고    scopus 로고
    • Promotion of bone repair by implantation of cryopreserved bone marrow-derived mononuclear cells in a rabbit model of steroid-associated osteonecrosis
    • PID: 22544527
    • Xie XH, Wang XL, He YX, Liu Z, Sheng H, Zhang G, Qin L (2012) Promotion of bone repair by implantation of cryopreserved bone marrow-derived mononuclear cells in a rabbit model of steroid-associated osteonecrosis. Arthritis Rheum 64:1562–1571
    • (2012) Arthritis Rheum , vol.64 , pp. 1562-1571
    • Xie, X.H.1    Wang, X.L.2    He, Y.X.3    Liu, Z.4    Sheng, H.5    Zhang, G.6    Qin, L.7
  • 31
    • 84890559123 scopus 로고    scopus 로고
    • Role of mesenchymal stem cells in bone regeneration and fracture repair: a review
    • PID: 23948983
    • Wang X, Wang Y, Gou W, Lu Q, Peng J, Lu S (2013) Role of mesenchymal stem cells in bone regeneration and fracture repair: a review. Int Orthop 37:2491–2498
    • (2013) Int Orthop , vol.37 , pp. 2491-2498
    • Wang, X.1    Wang, Y.2    Gou, W.3    Lu, Q.4    Peng, J.5    Lu, S.6
  • 35
    • 11444259467 scopus 로고    scopus 로고
    • Cartilage MRI T2 relaxation time mapping: overview and applications
    • PID: 15643574
    • Mosher TJ, Dardzinski BJ (2004) Cartilage MRI T2 relaxation time mapping: overview and applications. Semin Musculoskelet Radiol 8:355–368
    • (2004) Semin Musculoskelet Radiol , vol.8 , pp. 355-368
    • Mosher, T.J.1    Dardzinski, B.J.2
  • 37
    • 78650060236 scopus 로고    scopus 로고
    • Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation
    • PID: 20722018
    • Minogue BM, Richardson SM, Zeef LA, Freemont AJ, Hoyland JA (2010) Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation. Arthritis Rheum 62:3695–3705
    • (2010) Arthritis Rheum , vol.62 , pp. 3695-3705
    • Minogue, B.M.1    Richardson, S.M.2    Zeef, L.A.3    Freemont, A.J.4    Hoyland, J.A.5
  • 38
    • 84885882488 scopus 로고    scopus 로고
    • Antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes): a double-blind randomized clinical controlled trial of efficacy
    • PID: 23404353
    • Albert HB, Sorensen JS, Christensen BS, Manniche C (2013) Antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes): a double-blind randomized clinical controlled trial of efficacy. Eur Spine J 22:697–707
    • (2013) Eur Spine J , vol.22 , pp. 697-707
    • Albert, H.B.1    Sorensen, J.S.2    Christensen, B.S.3    Manniche, C.4
  • 40
    • 84892813793 scopus 로고    scopus 로고
    • Is low back pain after disc herniation with Modic type 1 changes a low-grade infection?
    • PID: 23471576
    • Aebi M (2013) Is low back pain after disc herniation with Modic type 1 changes a low-grade infection? Eur Spine J 22:689
    • (2013) Eur Spine J , vol.22 , pp. 689
    • Aebi, M.1
  • 41
    • 84901551492 scopus 로고    scopus 로고
    • The two papers of Hanne Albert et al. about Modic I changes of the vertebra published in the European Spine Journal of April 2013. Editorial
    • PID: 23884551
    • Aebi M (2013) The two papers of Hanne Albert et al. about Modic I changes of the vertebra published in the European Spine Journal of April 2013. Editorial. Eur Spine J 22:1693
    • (2013) Eur Spine J , vol.22 , pp. 1693
    • Aebi, M.1
  • 42
    • 84886783152 scopus 로고    scopus 로고
    • Letter to the editor concerning: “Antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes): a double-blind randomized controlled trial of efficacy” by Albert HB et al. Eur Spine J (2013) 22:697–707
    • PID: 23989683
    • Ahmad Z, Rai A, Donell S, Crawford R (2013) Letter to the editor concerning: “Antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes): a double-blind randomized controlled trial of efficacy” by Albert HB et al. Eur Spine J (2013) 22:697–707. Eur Spine J 22:2344–2345
    • (2013) Eur Spine J , vol.22 , pp. 2344-2345
    • Ahmad, Z.1    Rai, A.2    Donell, S.3    Crawford, R.4
  • 43
    • 84893413977 scopus 로고    scopus 로고
    • From narcotics to antibiotics: evolving concepts in the treatment of lower back pain
    • PID: 24035987
    • Almefty KK, Turner JD, Theodore N (2013) From narcotics to antibiotics: evolving concepts in the treatment of lower back pain. World Neurosurg 80:442–443
    • (2013) World Neurosurg , vol.80 , pp. 442-443
    • Almefty, K.K.1    Turner, J.D.2    Theodore, N.3
  • 44
    • 84881552421 scopus 로고    scopus 로고
    • Do these results apply to the ‘intervention naive’ patient?
    • PID: 23846729
    • Dean BJ (2013) Do these results apply to the ‘intervention naive’ patient? Eur Spine J 22:1702
    • (2013) Eur Spine J , vol.22 , pp. 1702
    • Dean, B.J.1
  • 45
    • 84881557340 scopus 로고    scopus 로고
    • Letter to the editor concerning: “Antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes): a double-blind randomized controlled trial of efficacy” by Albert HB et al. Eur Spine J 22:697–707
    • PID: 23852437
    • Sotto A, Dupeyron A (2013) Letter to the editor concerning: “Antibiotic treatment in patients with chronic low back pain and vertebral bone edema (Modic type 1 changes): a double-blind randomized controlled trial of efficacy” by Albert HB et al. Eur Spine J 22:697–707. Eur Spine J 22:1704–1705
    • (2013) Eur Spine J , vol.22 , pp. 1704-1705
    • Sotto, A.1    Dupeyron, A.2
  • 46
    • 84883134166 scopus 로고    scopus 로고
    • Antibiotics a cure for back pain, a false dawn or a new era?
    • PID: 23846728
    • O’Dowd J, Casey A (2013) Antibiotics a cure for back pain, a false dawn or a new era? Eur Spine J 22:1694–1697
    • (2013) Eur Spine J , vol.22 , pp. 1694-1697
    • O’Dowd, J.1    Casey, A.2
  • 48
    • 84893861358 scopus 로고    scopus 로고
    • Antibiotics for low back pain?
    • PID: 23989682
    • Lings S (2014) Antibiotics for low back pain? Eur Spine J 23:469–472
    • (2014) Eur Spine J , vol.23 , pp. 469-472
    • Lings, S.1


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