Promotion of bone repair by implantation of cryopreserved bone marrowderived mononuclear cells in a rabbit model of steroid-associated osteonecrosis

Arthritis and Rheumatism

Volumn 64, Issue 5, 2012, Pages 1562-1571

  Xie, Xin Hui ^a,b   Wang, Xin Luan ^a,c   He, Yi Xin ^a,d   Liu, Zhong ^a,d   Sheng, Hui ^a   Zhang, Ge ^a,d   Qin, Ling ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^c INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^d TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

STEROID;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DENSITY; BONE MARROW CELL; BONE MARROW DERIVED MONONUCLEAR CELL; BONE NECROSIS; BONE REMODELING; CELL DIFFERENTIATION; CELL ISOLATION; CELL THERAPY; CONTROL GROUP; CONTROLLED STUDY; CRYOPRESERVATION; EXPERIMENTAL RABBIT; FEMUR; ILIAC CREST; IN VITRO STUDY; MALE; MICRO-COMPUTED TOMOGRAPHY; MONONUCLEAR CELL; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; STEROID ASSOCIATED OSTEONECROSIS; THERAPY EFFECT; TISSUE REGENERATION;

EID: 84860442659     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.34525     Document Type: Article

References (48)

1. Chan MH, Chan PK, Griffith JF, Chan IH, Lit LC, Wong CK, et al. Steroid-induced osteonecrosis in severe acute respiratory syndrome: a retrospective analysis of biochemical markers of bone metabolism and corticosteroid therapy. Pathology 2006;38:229-35.
2. Marston SB, Gillingham K, Bailey RF, Cheng EY. Osteonecrosis of the femoral head after solid organ transplantation: a prospective study. J Bone Joint Surg Am 2002;84-A:2145-51.
3. Duran-Barragan S, Sandoval-Garcia L, Navarrete-Lorenzon M. Additive risk factors resulting in severe osteonecrosis in systemic lupus erythematosus [clinical image]. Arthritis Rheum 2010;62: 3276.
4. Farge D, Remy P, Poignet JL, Menoyo V, Bariety J, de Vernejoul MC. Isolated bone-end sclerosis simulating osteonecrosis after renal transplantation [letter]. Arthritis Rheum 1990;33:1444-5.
5. Gangji V, Toungouz M, Hauzeur JP. Stem cell therapy for osteonecrosis of the femoral head. Expert Opin Biol Ther 2005;5: 437-42.
6. Hernigou P, Poignard A, Manicom O, Mathieu G, Rouard H. The use of percutaneous autologous bone marrow transplantation in nonunion and avascular necrosis of bone. J Bone Joint Surg Br 2005;87:896-902.
7. Hernigou P, Beaujean F, Lambotte JC. Decrease in the mesenchymal stem-cell pool in the proximal femur in corticosteroidinduced osteonecrosis. J Bone Joint Surg Br 1999;81:349-55.
8. Hernigou P, Beaujean F. Abnormalities in the bone marrow of the iliac crest in patients who have osteonecrosis secondary to corticosteroid therapy or alcohol abuse. J Bone Joint Surg Am 1997;79: 1047-53.
9. Zhang G, Sheng H, He YX, Xie XH, Wang YX, Lee KM, et al. Continuous occurrence of both insufficient neovascularization and elevated vascular permeability in rabbit proximal femur during inadequate repair of steroid-associated osteonecrotic lesions. Arthritis Rheum 2009;60:2966-77.
10. Mont MA, Carbone JJ, Fairbank AC. Core decompression versus nonoperative management for osteonecrosis of the hip. Clin Orthop Relat Res 1996:169-78.
11. Castro FP Jr, Barrack RL. Core decompression and conservative treatment for avascular necrosis of the femoral head: a meta-analysis. Am J Orthop (Belle Mead NJ) 2000;29:187-94.
12. Sahajpal DT, Zuckerman JD. Core decompression for nontraumatic osteonecrosis of the humeral head: a technique article. Bull NYU Hosp Jt Dis 2008;66:118-9.
13. Tang TT, Lu B, Yue B, Xie XH, Xie YZ, Dai KR, et al. Treatment of osteonecrosis of the femoral head with hBMP-2-gene-modified tissue-engineered bone in goats. J Bone Joint Surg Br 2007;89: 127-9.
14. Scully SP, Aaron RK, Urbaniak JR. Survival analysis of hips treated with core decompression or vascularized fibular grafting because of avascular necrosis. J Bone Joint Surg Am 1998;80: 1270-5.
15. Sheng H, Zhang G, Cheung WH, Chan CW, Wang YX, Lee KM, et al. Elevated adipogenesis of marrow mesenchymal stem cells during early steroid-associated osteonecrosis development. J Orthop Surg Res 2007;2:15.
16. Hernigou P, Poignard A, Zilber S, Rouard H. Cell therapy of hip osteonecrosis with autologous bone marrow grafting. Indian J Orthop 2009;43:40-5.
17. Casado-Diaz A, Santiago-Mora R, Jimenez R, Caballero-Villarraso J, Herrera C, Torres A, et al. Cryopreserved human bone marrow mononuclear cells as a source of mesenchymal stromal cells: application in osteoporosis research. Cytotherapy 2008;10: 460-8.
18. Sheng H, Zhang G, Wang X, Lee K, Yao X, Leung K, et al. Phytochemical molecule icariin stimulates osteogenic but inhibits adipogenic differentiation of mesenchymal stem cells. Bone 2008; 43:S42-3.
19. Hisatome T, Yasunaga Y, Yanada S, Tabata Y, Ikada Y, Ochi M. Neovascularization and bone regeneration by implantation of autologous bone marrow mononuclear cells. Biomaterials 2005;26: 4550-6.
20. Xie XH, Wang XL, Zhang G, Liu Z, Yao D, Hung LK, et al. Impaired bone healing in rabbits with steroid-induced osteonecrosis. J Bone Joint Surg Br 2011;93:558-65.
21. Qin L, Zhang G, Sheng H, Yeung KW, Yeung HY, Chan CW, et al. Multiple bioimaging modalities in evaluation of an experimental osteonecrosis induced by a combination of lipopolysaccharide and methylprednisolone. Bone 2006;39:863-71.
22. Yamamoto T, Irisa T, Sugioka Y, Sueishi K. Effects of pulse methylprednisolone on bone and marrow tissues: corticosteroidinduced osteonecrosis in rabbits. Arthritis Rheum 1997;40: 2055-64.
23. Zhang G, Qin L, Sheng H, Wang XL, Wang YX, Yeung DK, et al. A novel semisynthesized small molecule icaritin reduces incidence of steroid-associated osteonecrosis with inhibition of both thrombosis and lipid-deposition in a dose-dependent manner. Bone 2009;44:345-56.
24. Sheng H, Zhang G, Wang YX, Yeung DK, Griffith JF, Leung KS, et al. Functional perfusion MRI predicts later occurrence of steroid-associated osteonecrosis: an experimental study in rabbits. J Orthop Res 2009;27:742-7.
25. Kern S, Eichler H, Stoeve J, Kluter H, Bieback K. Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissue. Stem Cells 2006;24:1294-301.
26. Ma HL, Chen TH, Hung SC. Development of a new method in promoting fracture healing: multiple cryopreserved bone marrow injections using a rabbit model. Arch Orthop Trauma Surg 2004; 124:448-54.
27. De Ugarte DA, Morizono K, Elbarbary A, Alfonso Z, Zuk PA, Zhu M, et al. Comparison of multi-lineage cells from human adipose tissue and bone marrow. Cells Tissues Organs 2003;174: 101-9.
28. Hao W, Hu YY, Wei YY, Pang L, Lv R, Bai JP, et al. Collagen I gel can facilitate homogenous bone formation of adipose-derived stem cells in PLGA-β-TCP scaffold. Cells Tissues Organs 2008; 187:89-102.
29. Allegrini S Jr, Rumpel E, Kauschke E, Fanghanel J, Konig B Jr. Hydroxyapatite grafting promotes new bone formation and osseointegration of smooth titanium implants. Ann Anat 2006;188: 143-51.
30. Xie XH, Yu XW, Zeng SX, Du RL, Hu YH, Yuan Z, et al. Enhanced osteointegration of orthopaedic implant gradient coating composed of bioactive glass and nanohydroxyapatite. J Mater Sci Mater Med 2010;21:2165-73.
31. Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, et al. Bone histomorphometry: standardization of nomenclature, symbols, and units: report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 1987; 2:595-610.
32. Zhang G, Guo BS, Wu H, Tang T, Zhang BT, Zheng L, et al. A delivery system targeting bone formation surfaces to facilitate RNAi-based anabolic therapy. Nat Med 2012;18:307-14.
33. Zhang G, Qin L, Sheng H, Yeung KW, Yeung HY, Cheung WH, et al. Epimedium-derived phytoestrogen exert beneficial effect on preventing steroid-associated osteonecrosis in rabbits with inhibition of both thrombosis and lipid-deposition. Bone 2007;40: 685-92.
34. Gaucher S, Elie C, Verola O, Jarraya M. Viability of cryopreserved human skin allografts: effects of transport media and cryoprotectant. Cell Tissue Bank 2011. E-pub ahead of print.
35. Sumino Y, Hirata Y, Hanada M, Akita Y, Sato F, Mimata H. Long-term cryopreservation of pyramidalis muscle specimens as a source of striated muscle stem cells for treatment of post-prostatectomy stress urinary incontinence. Prostate 2011;71:1225-30.
36. Riggs R, Mayer J, Dowling-Lacey D, Chi TF, Jones E, Oehninger S. Does storage time influence postthaw survival and pregnancy outcome? An analysis of 11,768 cryopreserved human embryos. Fertil Steril 2010;93:109-15.
37. Liseth K, Ersvaer E, Abrahamsen JF, Nesthus I, Ryningen A, Bruserud O. Long-term cryopreservation of autologous stem cell grafts: a clinical and experimental study of hematopoietic and immunocompetent cells. Transfusion 2009;49:1709-19.
38. Kotobuki N, Hirose M, Machida H, Katou Y, Muraki K, Takakura Y, et al. Viability and osteogenic potential of cryopreserved human bone marrow-derived mesenchymal cells. Tissue Eng 2005; 11:663-73.
39. Hirose M, Kotobuki N, Machida H, Kitamura S, Ohgushi H, Tateishi T. Osteogenic potential of cryopreserved human bone marrow-derived mesenchymal cells after thawing in culture. Mater Sci Eng C 2004;24:355-9.
40. Li X, Jin L, Cui Q, Wang GJ, Balian G. Steroid effects on osteogenesis through mesenchymal cell gene expression. Osteoporos Int 2005;16:101-8.
41. Kanczler JM, Oreffo RO. Osteogenesis and angiogenesis: the potential for engineering bone. Eur Cell Mater 2008;15:100-14.
42. Gangji V, Hauzeur JP. Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells: surgical technique. J Bone Joint Surg Am 2005;87 Suppl 1:106-12.
43. Gangji V, Hauzeur JP, Matos C, De Maertelaer V, Toungouz M, Lambermont M. Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells: a pilot study. J Bone Joint Surg Am 2004;86-A:1153-60.
44. Hernigou P, Beaujean F. Treatment of osteonecrosis with autologous bone marrow grafting. Clin Orthop Relat Res 2002;405: 14-23.
45. Wang BL, Sun W, Shi ZC, Zhang NF, Yue DB, Guo WS, et al. Treatment of nontraumatic osteonecrosis of the femoral head with the implantation of core decompression and concentrated autologous bone marrow containing mononuclear cells. Arch Orthop Trauma Surg 2010;130:859-65.
46. Galmes A, Besalduch J, Bargay J, Matamoros N, Morey M, Novo A, et al. A simplified method for cryopreservation of hematopoietic stem cells with -80 degrees C mechanical freezer with dimethyl sulfoxide as the sole cryoprotectant. Leuk Lymphoma 1995;17:181-4.
47. Fan M, Peng J, Wang A, Zhang L, Liu B, Ren Z, et al. Emu model of full-range femoral head osteonecrosis induced focally by an alternating freezing and heating insult. J Int Med Res 2011;39: 187-98.
48. Kuribayashi M, Fujioka M, Takahashi KA, Arai Y, Hirata T, Nakajima S, et al. Combination analysis of three polymorphisms for predicting the risk for steroid-induced osteonecrosis of the femoral head. J Orthop Sci 2008;13:297-303.