Protective effect of metformin on renal injury of C57BL/6J mouse treated with high fat diet

Pharmazie

Volumn 69, Issue 12, 2014, Pages 904-908

  Zhang, Shao Qing ^a   Sun, Yi Ting ^a   Xu, Tian Hua ^a   Zhang, Xue Feng ^a   Liu, Ying Zhong ^a   Ma, Jian Fei ^a   Wang, Li Ning ^a   Yao, Li ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; GLUCOSE; HIGH DENSITY LIPOPROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MESSENGER RNA; METFORMIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; ANTIDIABETIC AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSESSMENT OF HUMANS; BODY WEIGHT; C57BL 6 MOUSE; CELL INFILTRATION; CHOLESTEROL BLOOD LEVEL; DRUG EFFECT; GLUCOSE BLOOD LEVEL; INFLAMMATORY CELL; INSULIN SENSITIVITY; INSULIN SENSITIVITY INDEX; KIDNEY HYPERTROPHY; KIDNEY INJURY; LIPID DIET; LIPID STORAGE; LOW FAT DIET; MALE; METABOLIC DISORDER; METABOLIC SYNDROME X; MOUSE; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TREATMENT DURATION; WESTERN BLOTTING; ACUTE KIDNEY INJURY; ADVERSE EFFECTS; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED; DRUG EFFECTS; KIDNEY; LIPID METABOLISM; METABOLISM; NEPHRITIS; PATHOLOGY;

ACUTE KIDNEY INJURY; ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DIET, HIGH-FAT; HYPOGLYCEMIC AGENTS; KIDNEY; LIPID METABOLISM; MALE; METFORMIN; MICE; MICE, INBRED C57BL; NEPHRITIS; OXIDATIVE STRESS;

EID: 84920760101     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2014.4509     Document Type: Article

References (24)

1. Awazawa M, Ueki K, Inabe K,Yamauchi T, KanekoK, OkazakiY, Bardeesy N, Ohnishi S, Nagai R, Kadowaki T (2009) Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway. Biochem Biophys Res Commun 382: 51-56.
2. Bagby SP (2004) Obesity-initiated metabolic syndrome and the kidney: a recipe for chronic kidney disease? J Am Soc Nephrol 15: 2775-2791.
3. Borst SE (2004) The role of TNF-alpha in insulin resistance. Endocrine 23: 177-182.
4. Ceolotto G, Gallo A, Papparella I, Franco L, Murphy E, Iori E, Pagnin E, Fadini GP, Albiero M, Semplicini A, Avogaro A (2007) Rosiglitazone reduces glucose-induced oxidative stress mediated by NAD(P)H oxidase via AMPK-dependent mechanism. Arterioscler Thromb Vasc Biol 27: 2627-2633.
5. Clarke PR, Hardie DG (1990) Regulation of HMG-CoA reductase: identification of the site phosphorylated by the AMP-activated protein kinase in vitro and in intact rat liver. Embo J 9: 2439-2446.
6. Deji N,Kume S, Araki S, Soumura M, SugimotoT, Isshiki K, Chin-Kanasaki M, Sakaguchi M, Koya D, Haneda M, Kashiwagi A, Uzu T (2009) Structural and functional changes in the kidneys of high-fat diet-induced obese mice. Am J Physiol Renal Physiol 296: F118-F126.
7. Ebenezer PJ, Mariappan N, Elks CM, Haque M, Francis J (2009) Dietinduced renal changes in Zucker rats are ameliorated by the superoxide dismutase mimetic TEMPOL. Obesity 17: 1994-2002.
8. Hallows KR, Mount PF, Pastor-Soler NM, Power DA (2010) Role of the energy sensor AMP-activated protein kinase in renal physiology and disease. Am J Physiol Renal Physiol 298: F1067-F1077.
9. Hunley TE, Ma LJ, Kon V (2010) Scope and mechanisms of obesity-related renal disease. Curr Opin Nephrol Hypertens 19: 227-234.
10. Jeong HW, Hsu KC, Lee JW, Ham M, Huh JY, Shin HJ, Kim WS, Kim JB (2009) Berberine suppresses proinflammatory responses through AMPK activation in macrophages. Am J Physiol Endocrinol Metab 296: E955-E964.
11. Jiang T, Wang Z, Proctor G, Moskowitz S, Liebman SE, Rogers T, Lucia MS, Li J, Levi M (2005) Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway. J Biol Chem 280: 32317-32325.
12. Kim HJ, Moradi H,Yuan J, Norris K,VaziriND(2009) Renal mass reduction results in accumulation of lipids and dysregulation of lipid regulatory proteins in the remnant kidney. Am J Physiol Renal Physiol 296: F1297-F1306.
13. Kim WS, Lee YS, Cha SH, Jeong HW, Choe SS, Lee MR, Oh GT, Park HS, Lee KU, LaneMD,KimJB (2009) Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity. Am J Physiol Endocrinol Metab 296: E812-E819.
14. Knight SF, Imig JD (2007) Obesity, insulin resistance, and renal function. Microcirculation 14: 349-362.
15. Kume S, Uzu T, Araki S, Sugimoto T, Isshiki K, Chin-Kanasaki M, Sakaguchi M, Kubota N, Terauchi Y, Kadowaki T, Haneda M, Kashiwagi A, Koya D (2007) Role of altered renal lipid metabolism in the development of renal injury induced by a high-fat diet. J Am Soc Nephrol 18: 2715-2723.
16. Lu DY, Tang CH, Chen YH, Wei IH (2010) Berberine suppresses neuroinflammatory responses through AMP-activated protein kinase activation in BV-2 microglia. J Cell Biochem 110: 697-705.
17. Mathieu P, Poirier P, Pibarot P, Lemieux I, Despres JP (2009) Visceral obesity: the link among inflammation, hypertension, and cardiovascular disease. Hypertension 53: 577-584.
18. Sag D, Carling D, Stout RD, Suttles J (2008) Adenosine 5'-monophosphateactivated protein kinase promotes macrophage polarization to an antiinflammatory functional phenotype. J Immunol 181: 8633-8641.
19. Schaffer JE (2003) Lipotoxicity: when tissues overeat. Curr Opin Lipidol 14: 281-287.
20. Sharma K, Ramachandrarao S, Qiu G, Usui HK, Zhu Y, Dunn SR, Ouedraogo R, Hough K, McCue P, Chan L, Falkner B, Goldstein BJ (2008) Adiponectin regulates albuminuria and podocyte function in mice. J Clin Invest 118: 1645-1656.
21. Wu Y, Liu Z, Xiang Z, Zeng C, Chen Z, Ma X, Li L (2006) Obesityrelated glomerulopathy: insights from gene expression profiles of the glomeruli derived from renal biopsy samples. Endocrinology 147: 44-50.
22. Yuan HD, Yuan HY, Chung SH, Jin GZ, Piao GC (2010) An active part of Artemisia sacrorum Ledeb. attenuates hepatic lipid accumulation through activating AMP-activated protein kinase in human HepG2 cells. Biosci Biotechnol Biochem 74: 322-328.
23. Zang M, Zuccollo A, Hou X, Nagata D, Walsh K, Herscovitz H, Brecher P, Ruderman NB, Cohen RA (2004) AMP-activated protein kinase is required for the lipid-lowering effect of metformin in insulin-resistant human HepG2 cells. J Biol Chem 279: 47898-47905.
24. Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N, Musi N, Hirshman MF, Goodyear LJ, Moller DE (2001) Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 108: 1167-1174.