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Volumn 5, Issue 1, 2015, Pages

The effect of simvastatin on inflammatory cytokines in community-acquired pneumonia: A randomised, double-blind, placebo-controlled trial

Author keywords

[No Author keywords available]

Indexed keywords

AMINOTRANSFERASE; C REACTIVE PROTEIN; CREATINE KINASE; INTERLEUKIN 10; INTERLEUKIN 6; PLACEBO; SIMVASTATIN; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; OXYGEN;

EID: 84920742364     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2014-006251     Document Type: Article
Times cited : (38)

References (22)
  • 1
    • 33847155159 scopus 로고    scopus 로고
    • IDSA/ATS consensus guidelines on the management of community-acquired pneumonia in adults
    • Mandell LA, Wunderink RG, Anzueto A, et al. IDSA/ATS consensus guidelines on the management of community-acquired pneumonia in adults. Clin Infect Dis 2007;44(Suppl 2):S27-72.
    • (2007) Clin Infect Dis , vol.44 , pp. S27-S72
    • Mandell, L.A.1    Wunderink, R.G.2    Anzueto, A.3
  • 2
    • 0030031642 scopus 로고    scopus 로고
    • Prognosis and outcomes of patients with community-acquired pneumonia. A meta-analysis
    • Fine MJ, Smith MA, Carson CA, et al. Prognosis and outcomes of patients with community-acquired pneumonia. A meta-analysis. JAMA 1996;275:134-41.
    • (1996) JAMA , vol.275 , pp. 134-141
    • Fine, M.J.1    Smith, M.A.2    Carson, C.A.3
  • 3
    • 0035879380 scopus 로고    scopus 로고
    • Etiology, reasons for hospitalization, risk classes, and outcomes of community-acquired pneumonia in patients hospitalized on the basis of conventional admission criteria
    • Rosón B, Carratalà J, Dorca J, et al. Etiology, reasons for hospitalization, risk classes, and outcomes of community-acquired pneumonia in patients hospitalized on the basis of conventional admission criteria. Clin Infect Dis 2001;33:158-65.
    • (2001) Clin Infect Dis , vol.33 , pp. 158-165
    • Rosón, B.1    Carratalà, J.2    Dorca, J.3
  • 4
    • 60449119244 scopus 로고    scopus 로고
    • Mortality in ICU patients with bacterial community-acquired pneumonia: When antibiotics are not enough
    • Rodriguez A, Lisboa T, Blot S, et al. Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough. Intensive Care Med 2009;35:430-8.
    • (2009) Intensive Care Med , vol.35 , pp. 430-438
    • Rodriguez, A.1    Lisboa, T.2    Blot, S.3
  • 5
    • 0032513753 scopus 로고    scopus 로고
    • Time to clinical stability in patients hospitalized with community-acquired pneumonia: Implications for practice guidelines
    • Halm EA, Fine MJ, Marrie TJ, et al. Time to clinical stability in patients hospitalized with community-acquired pneumonia: implications for practice guidelines. JAMA 1998;279:1452-7.
    • (1998) JAMA , vol.279 , pp. 1452-1457
    • Halm, E.A.1    Fine, M.J.2    Marrie, T.J.3
  • 6
    • 72549107435 scopus 로고    scopus 로고
    • Stability in community-acquired pneumonia: One step forward with markers?
    • Menéndez R, Martinez R, Reyes S, et al. Stability in community-acquired pneumonia: one step forward with markers? Thorax 2009;64:987-92.
    • (2009) Thorax , vol.64 , pp. 987-992
    • Menéndez, R.1    Martinez, R.2    Reyes, S.3
  • 7
    • 34548022149 scopus 로고    scopus 로고
    • Understanding the inflammatory cytokine response in pneumonia and sepsis
    • Kellum JA, Kong L, Fink MP, et al. Understanding the inflammatory cytokine response in pneumonia and sepsis. Arch Intern Med 2007;167:1655-63.
    • (2007) Arch Intern Med , vol.167 , pp. 1655-1663
    • Kellum, J.A.1    Kong, L.2    Fink, M.P.3
  • 8
    • 0141563840 scopus 로고    scopus 로고
    • Molecular inflammatory responses measured in blood of patients with severe community-acquired pneumonia
    • Fernández-Serrano S, Dorca J, Coromines M, et al. Molecular inflammatory responses measured in blood of patients with severe community-acquired pneumonia. Clin Diagn Lab Immunol 2003;10:813-20.
    • (2003) Clin Diagn Lab Immunol , vol.10 , pp. 813-820
    • Fernández-Serrano, S.1    Dorca, J.2    Coromines, M.3
  • 9
    • 77249126866 scopus 로고    scopus 로고
    • Statins for community-acquired pneumonia: Current state of the science
    • Viasus D, Garcia-Vidal C, Gudiol F, et al. Statins for community-acquired pneumonia: current state of the science. Eur J Clin Microbiol Infect Dis 2010;29:143-52.
    • (2010) Eur J Clin Microbiol Infect Dis , vol.29 , pp. 143-152
    • Viasus, D.1    Garcia-Vidal, C.2    Gudiol, F.3
  • 10
    • 54349122201 scopus 로고    scopus 로고
    • Prior statin use is associated with improved outcomes in community-acquired pneumonia
    • Chalmers JD, Singanayagam A, Murray MP, et al. Prior statin use is associated with improved outcomes in community-acquired pneumonia. Am J Med 2008;121:1002-7.
    • (2008) Am J Med , vol.121 , pp. 1002-1007
    • Chalmers, J.D.1    Singanayagam, A.2    Murray, M.P.3
  • 11
    • 54949095097 scopus 로고    scopus 로고
    • Preadmission use of statins and outcomes after hospitalization with pneumonia: Population-based cohort study of 29,900 patients
    • Thomsen RW, Riis A, Kornum JB, et al. Preadmission use of statins and outcomes after hospitalization with pneumonia: population-based cohort study of 29,900 patients. Arch Intern Med 2008;168:2081-7.
    • (2008) Arch Intern Med , vol.168 , pp. 2081-2087
    • Thomsen, R.W.1    Riis, A.2    Kornum, J.B.3
  • 12
    • 42949123466 scopus 로고    scopus 로고
    • Impact of statins and angiotensin-converting enzyme inhibitors on mortality of subjects hospitalised with pneumonia
    • Mortensen EM, Pugh MJ, Copeland LA, et al. Impact of statins and angiotensin-converting enzyme inhibitors on mortality of subjects hospitalised with pneumonia. Eur Respir J 2008;31:611-7.
    • (2008) Eur Respir J , vol.31 , pp. 611-617
    • Mortensen, E.M.1    Pugh, M.J.2    Copeland, L.A.3
  • 13
    • 0031012761 scopus 로고    scopus 로고
    • A prediction rule to identify low-risk patients with community-acquired pneumonia
    • Fine MJ, Auble TE, Yealy DM, et al. A prediction rule to identify low-risk patients with community-acquired pneumonia. N Engl J Med 1997;336:243-50.
    • (1997) N Engl J Med , vol.336 , pp. 243-250
    • Fine, M.J.1    Auble, T.E.2    Yealy, D.M.3
  • 14
    • 33750958903 scopus 로고    scopus 로고
    • Statins and outcomes in patients admitted to hospital with community acquired pneumonia: Population based prospective cohort study
    • Majumdar SR, McAlister FA, Eurich DT, et al. Statins and outcomes in patients admitted to hospital with community acquired pneumonia: population based prospective cohort study. BMJ 2006;333:999.
    • (2006) BMJ , vol.333 , pp. 999
    • Majumdar, S.R.1    McAlister, F.A.2    Eurich, D.T.3
  • 15
    • 84875818387 scopus 로고    scopus 로고
    • A multicentre randomised trial of atorvastatin therapy in intensive care patients with severe sepsis
    • The ANZ-STATInS Investigators-ANZICS Clinical Trials Group.
    • Kruger P, Bailey M, Bellomo R, et al.; The ANZ-STATInS Investigators-ANZICS Clinical Trials Group. A multicentre randomised trial of atorvastatin therapy in intensive care patients with severe sepsis. Am J Respir Crit Care Med 2013;187:743-50.
    • (2013) Am J Respir Crit Care Med , vol.187 , pp. 743-750
    • Kruger, P.1    Bailey, M.2    Bellomo, R.3
  • 16
    • 79952732359 scopus 로고    scopus 로고
    • Continuation of statin therapy in patients with presumed infection: A randomized controlled trial
    • Kruger PS, Harward ML, Jones MA, et al. Continuation of statin therapy in patients with presumed infection: a randomized controlled trial. Am J Respir Crit Care Med 2011;183:774-81.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 774-781
    • Kruger, P.S.1    Harward, M.L.2    Jones, M.A.3
  • 17
    • 67649364708 scopus 로고    scopus 로고
    • The effects of statin therapy on inflammatory cytokines in patients with bacterial infections: A randomized double-blind placebo controlled clinical trial
    • Novack V, Eisinger M, Frenkel A, et al. The effects of statin therapy on inflammatory cytokines in patients with bacterial infections: a randomized double-blind placebo controlled clinical trial. Intensive Care Med 2009;35:1255-60.
    • (2009) Intensive Care Med , vol.35 , pp. 1255-1260
    • Novack, V.1    Eisinger, M.2    Frenkel, A.3
  • 18
    • 84870725702 scopus 로고    scopus 로고
    • Randomized double-blind placebo-controlled trial of 40 mg/day of atorvastatin in reducing the severity of sepsis in ward patients (ASEPSIS Trial)
    • Patel JM, Snaith C, Thickett DR, et al. Randomized double-blind placebo-controlled trial of 40 mg/day of atorvastatin in reducing the severity of sepsis in ward patients (ASEPSIS Trial). Crit Care 2012;16:R231.
    • (2012) Crit Care , vol.16 , pp. R231
    • Patel, J.M.1    Snaith, C.2    Thickett, D.R.3
  • 19
    • 84901759539 scopus 로고    scopus 로고
    • National Heart, Lung, and Blood Institute ARDS Clinical Trials Network. Rosuvastatin for sepsis-associated acute respiratory distress syndrome
    • Truwit JD, Bernard GR, Steingrub J, et al. National Heart, Lung, and Blood Institute ARDS Clinical Trials Network. Rosuvastatin for sepsis-associated acute respiratory distress syndrome. N Engl J Med 2014;370:2191-200.
    • (2014) N Engl J Med , vol.370 , pp. 2191-2200
    • Truwit, J.D.1    Bernard, G.R.2    Steingrub, J.3
  • 20
    • 21844463540 scopus 로고    scopus 로고
    • Statin treatment after onset of sepsis in a murine model improves survival
    • Merx MW, Liehn EA, Graf J, et al. Statin treatment after onset of sepsis in a murine model improves survival. Circulation 2005;112:117-24.
    • (2005) Circulation , vol.112 , pp. 117-124
    • Merx, M.W.1    Liehn, E.A.2    Graf, J.3
  • 21
    • 77952630881 scopus 로고    scopus 로고
    • Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection
    • Gogos C, Kotsaki A, Pelekanou A, et al. Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection. Crit Care 2010;14:R96.
    • (2010) Crit Care , vol.14 , pp. R96
    • Gogos, C.1    Kotsaki, A.2    Pelekanou, A.3
  • 22
    • 65449181616 scopus 로고    scopus 로고
    • Rhabdomyolysis reports show interaction between simvastatin and CYP3A4 inhibitors
    • Rowan C, Brinker AD, Nourjah P, et al. Rhabdomyolysis reports show interaction between simvastatin and CYP3A4 inhibitors. Pharmacoepidemiol Drug Saf 2009;18:301-9.
    • (2009) Pharmacoepidemiol Drug Saf , vol.18 , pp. 301-309
    • Rowan, C.1    Brinker, A.D.2    Nourjah, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.