The effects of statin therapy on inflammatory cytokines in patients with bacterial infections: A randomized double-blind placebo controlled clinical trial

Intensive Care Medicine

Volumn 35, Issue 7, 2009, Pages 1255-1260

  Novack, Victor ^b   Eisinger, Miruna ^b   Frenkel, Amit ^a   Terblanche, Marius ^c   Adhikari, Neill K J ^d   Douvdevani, Amos ^b   Amichay, Doron ^b   Almog, Yaniv ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^c ST THOMAS HOSPITAL   (United Kingdom)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Cytokines; Infection; Inflammation; Sepsis; Statins

Indexed keywords

CYTOKINE; INTERLEUKIN 6; PLACEBO; SIMVASTATIN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; BACTERIAL INFECTION; CLINICAL TRIAL; COMORBIDITY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE SEVERITY; DOUBLE BLIND PROCEDURE; DRUG MECHANISM; FEMALE; HUMAN; INTENSIVE CARE UNIT; MAJOR CLINICAL STUDY; MALE; RANDOMIZED CONTROLLED TRIAL; SEPSIS; TREATMENT OUTCOME;

AGED; AGED, 80 AND OVER; BACTERIAL INFECTIONS; CYTOKINES; DOUBLE-BLIND METHOD; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INFLAMMATION MEDIATORS; MALE; MIDDLE AGED; SEPSIS; SIMVASTATIN;

EID: 67649364708     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-009-1429-0     Document Type: Article

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