Nonalcoholic fatty liver disease is underrecognized in the primary care setting

American Journal of Gastroenterology

Volumn 110, Issue 1, 2015, Pages 10-14

  Blais, Pierre ^a   Husain, Nisreen ^a   Kramer, Jennifer R ^a,b   Kowalkowski, Marc ^a,b   El Serag, Hashem ^a,b   Kanwal, Fasiha ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; COMORBIDITY; DIET; EXERCISE; FEMALE; HEALTH CARE UTILIZATION; HUMAN; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; NONALCOHOLIC FATTY LIVER; PATIENT REFERRAL; PRIMARY MEDICAL CARE; BLOOD; BODY MASS; FACTUAL DATABASE; MIDDLE AGED; NON-ALCOHOLIC FATTY LIVER DISEASE; PREVALENCE; PRIMARY HEALTH CARE; RISK FACTOR; UNITED STATES; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ALANINE TRANSAMINASE; BODY MASS INDEX; DATABASES, FACTUAL; FEMALE; HUMANS; MALE; MIDDLE AGED; NON-ALCOHOLIC FATTY LIVER DISEASE; PREVALENCE; PRIMARY HEALTH CARE; REFERRAL AND CONSULTATION; RISK FACTORS; UNITED STATES; YOUNG ADULT;

EID: 84920659773     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2014.134     Document Type: Article

References (18)

1. Lazo M, Hernaez R, Eberhardt MS et al. Prevalence of Nonalcoholic Fatty Liver Disease in the United Status: The Third National Health and Nutrition Examination Survey, 1988-1994. Am J Epidemiol 2013;178: 38-45.
2. Browning JD, Szczepaniak LS, Dobbins R et al. Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology 2004;40: 1387-95.
3. White DL, Kanwal F, El-Serag HB. Association between nonalcoholic fatty liver disease and risk for hepatocellular cancer, based on systematic review. Clin Gastroenterol Hepatol 2012;10: 1342-59.e2.
4. Davila JA, Morgan RO, Shaib Y et al. Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study. Gut 2005;54: 533-9.
5. Wong VW, Wong GL, Choi PC et al. Disease progression of non-alcoholic fatty liver disease: a prospective study with paired liver biopsies at 3 years. Gut 2010;59: 969-74.
6. Peng L, Wang J, Li F. Weight reduction for non-alcoholic fatty liver disease. Cochrane Database Syst Rev 2011, CD003619.
7. Angulo P, Hui JM, Marchesini G et al. The NAFLD fi brosis score: a noninvasive system that identifi es liver fi brosis in patients with NAFLD. Hepatology 2007;45: 846-54.
8. Chalasani N, Younossi Z, Lavine JE et al. The diagnosis and management of non-alcoholic fatty liver disease: practice guideline by the American Gastroenterological Association, American Association for the Study of Liver Diseases, and American College of Gastroenterology. Gastroenterology 2012;142: 1592-609.
9. McPherson S, Stewart SF, Henderson E et al. Simple non-invasive fi brosis scoring systems can reliably exclude advanced fi brosis in patients with nonalcoholic fatty liver disease. Gut 2010;59: 1265-9.
10. Kallman JB, Arsalla A, Park V et al. Screening for hepatitis B, C and non-alcoholic fatty liver disease: a survey of community-based physicians. Aliment Pharmacol Ther 2009;29: 1019-24.
11. Said A, Gagovic V, Malecki K et al. Primary care practitioners survey of non-alcoholic fatty liver disease. Ann Hepatol 2013;12: 758-65.
12. Wieland AC, Quallick M, Truesdale A et al. Identifying practice gaps to optimize medical care for patients with nonalcoholic fatty liver disease. Dig Dis Sci 2013;58: 2809-16.
13. Mofrad P, Contos MJ, Hague M et al. Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values. Hepatology 2003;37: 1286-92.
14. Wong VW, Wong GL, Tsang SW et al. Metabolic and histologic features of non-alcoholic fatty liver disease patients with diff erent serum alanine aminotransferase levels. Aliment Pharmacol Ther 2009;29: 387-96.
15. Angulo P, Keach JC, Batts KP et al. Independent predictors of liver fi brosis in patients with nonalcoholic steatohepatitis. Hepatology 1999;30: 1356-62.
16. Ratziu V, Giral P, Charlotte F et al. Liver fi brosis in overweight patients. Gastroenterology 2000;118: 1117-23.
17. Dixon JB, Bhathal PS, O ' Brien PE. Nonalcoholic fatty liver disease: predictors of nonalcoholic steatohepatitis and liver fi brosis in the severely obese. Gastroenterology 2001;121: 91-100.
18. Grandison GA, Angulo P. Can NASH be diagnosed, graded, and staged noninvasively Clin Liver Dis 2012;16: 567-85.