-
1
-
-
56249089380
-
The neglected tropical diseases of latin america and the Caribbean: a review of disease burden and distribution and a roadmap for control and elimination
-
Hotez PJ, Bottazzi ME, Franco-Paredes C, Ault SK, Periago MR, (2008) The neglected tropical diseases of latin america and the Caribbean: a review of disease burden and distribution and a roadmap for control and elimination. PLoS Negl Trop Dis 2: e300.
-
(2008)
PLoS Negl Trop Dis
, vol.2
, pp. e300
-
-
Hotez, P.J.1
Bottazzi, M.E.2
Franco-Paredes, C.3
Ault, S.K.4
Periago, M.R.5
-
2
-
-
77953082627
-
Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches
-
Urbina JA, (2010) Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches. Acta Trop 115: 55–68.
-
(2010)
Acta Trop
, vol.115
, pp. 55-68
-
-
Urbina, J.A.1
-
3
-
-
68949220484
-
The BENEFIT trial: testing the hypothesis that trypanocidal therapy is beneficial for patients with chronic Chagas heart disease
-
Marin-Neto JA, Rassi A, JrAvezum A, JrMattos AC, Rassi A, et al. (2009) The BENEFIT trial: testing the hypothesis that trypanocidal therapy is beneficial for patients with chronic Chagas heart disease. Mem Inst Oswaldo Cruz 104 Suppl 1: 319–324 BENEFIT: Evaluation of the Use of Antiparasital Drug (Benznidazole) in the Treatment of Chronic Chagas' Disease. Population Health Research Institute. Available: http://clinicaltrials.gov/. Identifier: NCT00123916.
-
(2009)
Mem Inst Oswaldo Cruz
, vol.104
, pp. 319-324
-
-
Marin-Neto, J.A.1
Rassi, A.2
Avezum, A.3
Mattos, A.C.4
Rassi, A.5
-
5
-
-
85015535992
-
-
Torrico F (2013) E1224–Results of proof of concept clinical trial in patients with chronic indeterminate Chagas disease. In: Proceedings of the 62nd Annual Meeting of the American Society of Tropical Medicine and Hygiene; November 13–17, 2013; Washington, DC. Proof-of-Concept Study of E1224 to Treat Adult Patients With Chagas Disease. Drugs for Neglected Diseases Initiative. Available: http://clinicaltrials.gov/. Identifier: NCT01489228.
-
-
-
-
6
-
-
85015529774
-
-
Molina I (2012) First clinical trial with posaconazole and benznidazole for the treatment of chronic Chagas disease. In: Proceedings of the XVIII International Congress of Tropical Medicine and Malaria; September 23–27, 2012; Rio de Janeiro, Brazil. Available: http://ictmm2012.ioc.fiocruz.br/program_25_sept.html. Accessed 8 September 2014. Clinical Trial For The Treatment Of Chronic Chagas Disease With Posaconazole And Benznidazole (CHAGASAZOL). Hospital Universitari Vall d'Hebron Research Institute. http://clinicaltrials.gov/. Identifier: NCT01162967.
-
-
-
-
7
-
-
85015507348
-
-
A Study of the Use of Oral Posaconazole (POS) in the Treatment of Asymptomatic Chronic Chagas Disease (P05267) (STOP CHAGAS). Merck Sharp & Dohme Corp. Available: http://clinicaltrials.gov/. Identifier: NCT01377480. Accessed 8 September 2014.
-
-
-
-
8
-
-
0035340666
-
Parasite persistence in the aetiology of Chagas disease
-
Tarleton RL, (2001) Parasite persistence in the aetiology of Chagas disease. Int J Parasitol 31: 549–553.
-
(2001)
Int J Parasitol
, vol.31
, pp. 549-553
-
-
Tarleton, R.L.1
-
9
-
-
1142291085
-
Chagas Disease: a role for autoimmunity?
-
Tarleton RL, (2003) Chagas Disease: a role for autoimmunity? Trends Parasitol 10: 447–451.
-
(2003)
Trends Parasitol
, vol.10
, pp. 447-451
-
-
Tarleton, R.L.1
-
10
-
-
84893436816
-
Towards a paradigm shift in the treatment of chronic Chagas disease
-
Viotti R, de Noya BA, Araujo-Jorge T, Grijalva MJ, Guhl F, et al. (2014) Towards a paradigm shift in the treatment of chronic Chagas disease. Antimicrob Agents Chemother 58: 635–639.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 635-639
-
-
Viotti, R.1
de Noya, B.A.2
Araujo-Jorge, T.3
Grijalva, M.J.4
Guhl, F.5
-
11
-
-
80051701708
-
Trypanocidal activity of nitroaromatic prodrugs: current treatments and future perspectives
-
Wilkinson SR, Bot C, Kelly JM, Hall BS, (2011) Trypanocidal activity of nitroaromatic prodrugs: current treatments and future perspectives. Curr Top Med Chem 11: 2072–2084.
-
(2011)
Curr Top Med Chem
, vol.11
, pp. 2072-2084
-
-
Wilkinson, S.R.1
Bot, C.2
Kelly, J.M.3
Hall, B.S.4
-
12
-
-
84869507989
-
Evaluation of benznidazole treatment combined with nifurtimox, posaconazole or AmBisome(R) in mice infected with Trypanosoma cruzi strains
-
Cencig S, Coltel N, Truyens C, Carlier Y, (2012) Evaluation of benznidazole treatment combined with nifurtimox, posaconazole or AmBisome(R) in mice infected with Trypanosoma cruzi strains. Int J Antimicrob Agents 40: 527–532.
-
(2012)
Int J Antimicrob Agents
, vol.40
, pp. 527-532
-
-
Cencig, S.1
Coltel, N.2
Truyens, C.3
Carlier, Y.4
-
13
-
-
84883372900
-
Benznidazole and posaconazole in experimental Chagas disease: positive interaction in concomitant and sequential treatments
-
Diniz Lde F, Urbina JA, de Andrade IM, Mazzeti AL, Martins TA, et al. (2013) Benznidazole and posaconazole in experimental Chagas disease: positive interaction in concomitant and sequential treatments. PLoS Negl Trop Dis 7: e2367.
-
(2013)
PLoS Negl Trop Dis
, vol.7
, pp. e2367
-
-
Diniz Lde, F.1
Urbina, J.A.2
de Andrade, I.M.3
Mazzeti, A.L.4
Martins, T.A.5
-
14
-
-
84891355403
-
Efficacy of alternate and combination drug treatment protocols in cure of Trypanosoma cruzi infection in mice
-
Bustamante J, Craft JM, Ketchie SA, Tarleton RL, (2014) Efficacy of alternate and combination drug treatment protocols in cure of Trypanosoma cruzi infection in mice. J Infect Dis 209: 150–162.
-
(2014)
J Infect Dis
, vol.209
, pp. 150-162
-
-
Bustamante, J.1
Craft, J.M.2
Ketchie, S.A.3
Tarleton, R.L.4
-
15
-
-
84872377363
-
Sequential combined treatment with allopurinol and benznidazole in the chronic phase of Trypanosoma cruzi infection: a pilot study
-
Perez-Mazliah DE, Alvarez MG, Cooley G, Lococo BE, Bertocchi G, et al. (2013) Sequential combined treatment with allopurinol and benznidazole in the chronic phase of Trypanosoma cruzi infection: a pilot study. J Antimicrob Chemother 68: 424–437.
-
(2013)
J Antimicrob Chemother
, vol.68
, pp. 424-437
-
-
Perez-Mazliah, D.E.1
Alvarez, M.G.2
Cooley, G.3
Lococo, B.E.4
Bertocchi, G.5
-
16
-
-
84889600741
-
Perpetual expression of PAMPs is necessary for optimal immune control and clearance of an otherwise persistent pathogen
-
Kurup SP, Tarleton RL, (2013) Perpetual expression of PAMPs is necessary for optimal immune control and clearance of an otherwise persistent pathogen. Nat Commun 4: 2616.
-
(2013)
Nat Commun
, vol.4
, pp. 2616
-
-
Kurup, S.P.1
Tarleton, R.L.2
-
17
-
-
84874923258
-
Improved chemical control of Chagas disease vectors in the dry Chaco region
-
Cecere MC, Vazquez-Prokopec GM, Ceballos LA, Boragno S, Zarate JE, et al. (2013) Improved chemical control of Chagas disease vectors in the dry Chaco region. J Med Entomol 50: 394–403.
-
(2013)
J Med Entomol
, vol.50
, pp. 394-403
-
-
Cecere, M.C.1
Vazquez-Prokopec, G.M.2
Ceballos, L.A.3
Boragno, S.4
Zarate, J.E.5
-
18
-
-
68949204573
-
Sustainability of vector control strategies in the Gran Chaco region: current challenges and possible approaches
-
Gurtler RE, (2009) Sustainability of vector control strategies in the Gran Chaco region: current challenges and possible approaches. Mem Inst Oswaldo Cruz 104 Suppl 1: 52–59.
-
(2009)
Mem Inst Oswaldo Cruz
, vol.104
, pp. 52-59
-
-
Gurtler, R.E.1
-
19
-
-
85015522268
-
-
Yadón ZE, Gürtler RE, Tobar F, Medici AC (2007) Decentralization and Management of Communicable Disease Control in Latin America. Buenos Aires: Pan American Health Organization. Available: http://www.paho.org/English/ad/dpc/cd/res-descentralizacion.htm. Accessed 8 September 2014.
-
-
-
-
20
-
-
19444373557
-
High resistance to pyrethroid insecticides associated with ineffective field treatments in Triatoma infestans (Hemiptera: Reduviidae) from Northern Argentina
-
Picollo MI, Vassena C, Santo Orihuela P, Barrios S, Zaidemberg M, et al. (2005) High resistance to pyrethroid insecticides associated with ineffective field treatments in Triatoma infestans (Hemiptera: Reduviidae) from Northern Argentina. J Med Entomol 42: 637–642.
-
(2005)
J Med Entomol
, vol.42
, pp. 637-642
-
-
Picollo, M.I.1
Vassena, C.2
Santo Orihuela, P.3
Barrios, S.4
Zaidemberg, M.5
-
21
-
-
77955396881
-
Insecticide resistance of Triatoma infestans (Hemiptera, Reduviidae) vector of Chagas disease in Bolivia
-
Lardeux F, Depickere S, Duchon S, Chavez T, (2010) Insecticide resistance of Triatoma infestans (Hemiptera, Reduviidae) vector of Chagas disease in Bolivia. Trop Med Int Health 15: 1037–1048.
-
(2010)
Trop Med Int Health
, vol.15
, pp. 1037-1048
-
-
Lardeux, F.1
Depickere, S.2
Duchon, S.3
Chavez, T.4
-
22
-
-
84869772134
-
Unexpected failures to control Chagas Disease vectors with pyrethroid spraying in northern Argentina
-
Gurevitz JM, Gaspe MS, Enriquez GF, Vassena CV, Alvarado-Otegui JA, et al. (2012) Unexpected failures to control Chagas Disease vectors with pyrethroid spraying in northern Argentina. J Med Entomol 49: 1379–1386.
-
(2012)
J Med Entomol
, vol.49
, pp. 1379-1386
-
-
Gurevitz, J.M.1
Gaspe, M.S.2
Enriquez, G.F.3
Vassena, C.V.4
Alvarado-Otegui, J.A.5
-
23
-
-
33748999569
-
Periurban Trypanosoma cruzi-infected Triatoma infestans, Arequipa, Peru
-
Levy MZ, Bowman NM, Kawai V, Waller LA, Cornejo del Carpio JG, et al. (2006) Periurban Trypanosoma cruzi-infected Triatoma infestans, Arequipa, Peru. Emerg Infect Dis 12: 1345–1352.
-
(2006)
Emerg Infect Dis
, vol.12
, pp. 1345-1352
-
-
Levy, M.Z.1
Bowman, N.M.2
Kawai, V.3
Waller, L.A.4
Cornejo del Carpio, J.G.5
-
24
-
-
50449093879
-
Urban transmission of Chagas disease in Cochabamba, Bolivia
-
Medrano-Mercado N, Ugarte-Fernandez R, Butron V, Uber-Busek S, Guerra HL, et al. (2008) Urban transmission of Chagas disease in Cochabamba, Bolivia. Mem Inst Oswaldo Cruz 103: 423–430.
-
(2008)
Mem Inst Oswaldo Cruz
, vol.103
, pp. 423-430
-
-
Medrano-Mercado, N.1
Ugarte-Fernandez, R.2
Butron, V.3
Uber-Busek, S.4
Guerra, H.L.5
-
25
-
-
84877154830
-
Oral transmission of Chagas disease: typing of Trypanosoma cruzi from five outbreaks occurred in Venezuela shows multiclonal and common infections in patients, vectors and reservoirs
-
Munoz-Calderon A, Diaz-Bello Z, Valladares B, Noya O, Lopez MC, et al. (2013) Oral transmission of Chagas disease: typing of Trypanosoma cruzi from five outbreaks occurred in Venezuela shows multiclonal and common infections in patients, vectors and reservoirs. Infect Genet Evol 17: 113–122.
-
(2013)
Infect Genet Evol
, vol.17
, pp. 113-122
-
-
Munoz-Calderon, A.1
Diaz-Bello, Z.2
Valladares, B.3
Noya, O.4
Lopez, M.C.5
-
27
-
-
64749110340
-
Challenges and opportunities for primary, secondary, and tertiary prevention of Chagas' disease
-
Rassi A, JrDias JC, Marin-Neto JA, Rassi A, (2009) Challenges and opportunities for primary, secondary, and tertiary prevention of Chagas' disease. Heart 95: 524–534.
-
(2009)
Heart
, vol.95
, pp. 524-534
-
-
Rassi, A.1
Dias, J.C.2
Marin-Neto, J.A.3
Rassi, A.4
-
28
-
-
70449562088
-
New, improved treatments for Chagas disease: from the R&D pipeline to the patients
-
Ribeiro I, Sevcsik AM, Alves F, Diap G, Don R, et al. (2009) New, improved treatments for Chagas disease: from the R&D pipeline to the patients. PLoS Negl Trop Dis 3: e484.
-
(2009)
PLoS Negl Trop Dis
, vol.3
, pp. e484
-
-
Ribeiro, I.1
Sevcsik, A.M.2
Alves, F.3
Diap, G.4
Don, R.5
-
29
-
-
72849122497
-
Changes in Trypanosoma cruzi-specific immune responses following treatment: surrogate markers of treatment efficacy
-
Laucella SA, Perez Mazliah D, Bertocchi G, Alvarez MG, Cooley G, et al. (2009) Changes in Trypanosoma cruzi-specific immune responses following treatment: surrogate markers of treatment efficacy. Clin Infect Dis 49: 1675–1684.
-
(2009)
Clin Infect Dis
, vol.49
, pp. 1675-1684
-
-
Laucella, S.A.1
Perez Mazliah, D.2
Bertocchi, G.3
Alvarez, M.G.4
Cooley, G.5
-
30
-
-
56149088543
-
High Throughput Selection of Effective Serodiagnostics for Trypanosoma cruzi infection
-
Cooley G, Etheridge RD, Boehlke C, Bundy B, Weatherly DB, et al. (2008) High Throughput Selection of Effective Serodiagnostics for Trypanosoma cruzi infection. PLoS Negl Trop Dis 2: e316.
-
(2008)
PLoS Negl Trop Dis
, vol.2
, pp. e316
-
-
Cooley, G.1
Etheridge, R.D.2
Boehlke, C.3
Bundy, B.4
Weatherly, D.B.5
-
31
-
-
79960870288
-
Short-term follow-up of chagasic patients after benzonidazole treatment using multiple serological markers
-
Fernandez-Villegas A, Pinazo MJ, Maranon C, Thomas MC, Posada E, et al. (2011) Short-term follow-up of chagasic patients after benzonidazole treatment using multiple serological markers. BMC Infect Dis 11: 206.
-
(2011)
BMC Infect Dis
, vol.11
, pp. 206
-
-
Fernandez-Villegas, A.1
Pinazo, M.J.2
Maranon, C.3
Thomas, M.C.4
Posada, E.5
-
32
-
-
84875463900
-
Certifying the interruption of Chagas disease transmission by native vectors: cui bono?
-
Abad-Franch F, Diotaiuti L, Gurgel-Goncalves R, Gurtler RE, (2013) Certifying the interruption of Chagas disease transmission by native vectors: cui bono? Mem Inst Oswaldo Cruz 108: 251–254.
-
(2013)
Mem Inst Oswaldo Cruz
, vol.108
, pp. 251-254
-
-
Abad-Franch, F.1
Diotaiuti, L.2
Gurgel-Goncalves, R.3
Gurtler, R.E.4
-
34
-
-
33745022123
-
Extinction of experimental Triatoma infestans populations following continuous exposure to dogs wearing deltamethrin-treated collars
-
Reithinger R, Ceballos L, Stariolo R, Davies CR, Gurtler RE, (2006) Extinction of experimental Triatoma infestans populations following continuous exposure to dogs wearing deltamethrin-treated collars. Am J Trop Med Hyg 74: 766–771.
-
(2006)
Am J Trop Med Hyg
, vol.74
, pp. 766-771
-
-
Reithinger, R.1
Ceballos, L.2
Stariolo, R.3
Davies, C.R.4
Gurtler, R.E.5
-
35
-
-
53749096984
-
Impregnated netting slows infestation by Triatoma infestans
-
Levy MZ, Quispe-Machaca VR, Ylla-Velasquez JL, Waller LA, Richards JM, et al. Impregnated netting slows infestation by Triatoma infestans. Am J Trop Med Hyg 79: 528–534.
-
Am J Trop Med Hyg
, vol.79
, pp. 528-534
-
-
Levy, M.Z.1
Quispe-Machaca, V.R.2
Ylla-Velasquez, J.L.3
Waller, L.A.4
Richards, J.M.5
|