Surgical excision versus Mohs' micrographic surgery for basal cell carcinoma of the face: A randomised clinical trial with 10 year follow-up

European Journal of Cancer

Volumn 50, Issue 17, 2014, Pages 3011-3020

  Van Loo, Eva ^a   Mosterd, Klara ^b,c   Krekels, Gertruud A M ^b,d   Roozeboom, Marieke H ^b,c   Ostertag, Judith U ^b,e   Dirksen, Carmen D ^b   Steijlen, Peter M ^b,c,f   Neumann, H A Martino ^b,g   Nelemans, Patty J ^b   Kelleners Smeets, Nicole W J ^b,c,f  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d MohsA Skin Cancer Clinic   (Netherlands)

^e Mohsklinieken ^*  (Netherlands)

^f CATHARINA HOSPITAL   (Netherlands)

^g ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Basal cell carcinoma; Facial; Mohs surgery; Randomised controlled trial; Surgical excision

Indexed keywords

ADULT; AGED; ARTICLE; BASAL CELL CARCINOMA; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CAUSE OF DEATH; CONTROLLED STUDY; CRYOTHERAPY; FACE BASAL CELL CARCINOMA; FACE CANCER; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; INTENTION TO TREAT ANALYSIS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MOHS MICROGRAPHIC SURGERY; OUTCOME ASSESSMENT; PATIENT SELECTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SURGICAL TECHNIQUE; TUMOR RECURRENCE; VERY ELDERLY; CARCINOMA, BASAL CELL; CHEMOSURGERY; CLINICAL TRIAL; FACIAL NEOPLASMS; KAPLAN MEIER METHOD; MORTALITY; MULTICENTER STUDY; NEOPLASM RECURRENCE, LOCAL; PROCEDURES; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, BASAL CELL; FACIAL NEOPLASMS; FEMALE; FOLLOW-UP STUDIES; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MOHS SURGERY; NEOPLASM RECURRENCE, LOCAL; PROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84920519889     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2014.08.018     Document Type: Article

References (27)

1. A. Lomas, J. Leonardi-Bee, and F. Bath-Hextall A systematic review of worldwide incidence of non-melanoma skin cancer Br J Dermatol 166 2012 1069 1080
2. S.C. Flohil, E.D. Vries, M. Neumann, J.-W. Coebergh, and T. Nijsten Incidence, prevalence and future trends of primary basal cell carcinoma in the Netherlands Acta Derm Venereol 91 2011 24 30
3. P.T. Ting, R. Kasper, and J.P. Arlette Metastatic basal cell carcinoma: report of two cases and literature review J Cutan Med Surg 9 2005 10 15
4. F.J. Bath-Hextall, W. Perkins, J. Bong, and H.C. Williams Interventions for basal cell carcinoma of the skin Cochrane Database Syst Rev 1 2007 CD003412
5. Ad Hoc Task Force S.M. Connolly, D.R. Baker, B.M. Coldiron, M.J. Fazio, and P.A. Storrs Appropriate use criteria for Mohs micrographic surgery: a report of the American academy of dermatology, American college of mohs surgery, American society for dermatologic surgery association, and the American society for Mohs surgery J Am Acad Dermatol 2012 67 2012 531 550
6. F.M. Muller, R.S. Dawe, H. Moseley, and C.J. Fleming Randomized comparison of Mohs micrographic surgery and surgical excision for small nodular basal cell carcinoma: tissue-sparing outcome Dermatol Surg 35 2009 1349 1354
7. K. Mosterd, G.A. Krekels, F.H. Nieman, J.U. Ostertag, B.A. Essers, and C.D. Dirksen Surgical excision versus Mohs' micrographic surgery for primary and recurrent basal-cell carcinoma of the face: a prospective randomised controlled trial with 5-years' follow-up Lancet Oncol 9 2008 1149 1156
8. J. Paoli, S. Daryoni, A.M. Wennberg, L. Mölne, M. Gillstedt, and M. Miocic 5-year recurrence rates of Mohs micrographic surgery for aggressive and recurrent facial basal cell carcinoma Acta Derm Venereol 91 2011 689 693
9. R.W. Griffiths, S.K. Suvarna, and J. Stone Do basal cell carcinomas recur after complete conventional surgical excision? Br J Plast Surg 58 2005 795 805
10. N.W. Smeets, D.I. Kuijpers, P. Nelemans, J.U. Ostertag, M.E. Verhaegh, and G.A. Krekels Mohs' micrographic surgery for treatment of basal cell carcinoma of the face - results of a retrospective study and review of the literature Br J Dermatol 151 2004 141 147
11. A.M. Wennberg, O. Larko, and B. Stenquist Five-year results of Mohs' micrographic surgery for aggressive facial basal cell carcinoma in Sweden Acta Derm Venereol 79 1999 370 372
12. C.G. Julian, and P.W. Bowers A prospective study of Mohs' micrographic surgery in two English centres Br J Dermatol 136 1997 515 518
13. D.E. Rowe, R.J. Carroll, and C.L. Day Jr. Long-term recurrence rates in previously untreated (primary) basal cell carcinoma: implications for patient follow-up J Dermatol Surg Oncol 15 1989 315 328
14. H. Randle Basal cell carcinoma. Identification and treatment of the high-risk patient Dermatol Surg 22 1996 255 261
15. A. Kyrgidis, K. Vahtsevanos, T.G. Tzellos, P. Xirou, K. Kitikidou, and K. Antoniades A 1062 patient-cohort study from a tertiary cancer referral hospital Eur J Dermatol 20 2010 276 282
16. N.W. Smeets, G.A. Krekels, J.U. Ostertag, B.A. Essers, C.D. Dirksen, and F.H. Nieman Surgical excision vs. Mohs' micrographic surgery for basal-cell carcinoma of the face: randomised controlled trial Lancet 364 2004 1766 1772
17. R.P. Rapini Comparison of methods for checking surgical margins J Am Acad Dermatol 23 1990 288 294
18. D.E. Rowe, R.J. Carroll, and C.L. Day Jr. Mohs surgery is the treatment of choice for recurrent (previously treated) basal cell carcinoma J Dermatol Surg Oncol 15 1989 424 431
19. H. Neumann, G. Krekels, and M. Verhaegh Treatment of 208 extensive basal cell carcinomas with Mohs micrographic surgery J Eur Acad Dermatol Venereol 6 1996 217 225
20. I. Leibovitch, S.C. Huilgol, D. Selva, S. Richards, and R. Paver Basal cell carcinoma treated with Mohs surgery in Australia I. Experience over 10 years J Am Acad Dermatol 53 2005 445 451
21. F. Veronese, P. Farinelli, E. Zavattaro, R. Zuccoli, D. Bonvini, and G. Leigheb Basal cell carcinoma of the head region: therapeutical results of 350 lesions treated with Mohs micrographic surgery J Eur Acad Dermatol Venereol 26 2011 838 843
22. M.K. Silverman, A.W. Kopf, R.S. Bart, C.M. Grin, and M.S. Levenstein Recurrence rates of treated basal cell carcinomas. Part 3: Surgical excision J Dermatol Surg Oncol 18 1992 471 476
23. K. Werlinger, G. Upton, and A. Moore Recurrence rates of primary nonmelanoma skin cancers treated by surgical excision compared to electrodesiccation-curettage in a private dermatological practice Dermatol Surg 28 2002 1138 1142
24. G. Boztepe, S. Hohenleutner, M. Landthaler, and U. Hohenleutner Munich method of micrographic surgery for basal cell carcinomas: 5-year recurrence rates with life-table analysis Acta Derm Venereol 84 2004 218 222
25. N.R. Telfer, G.B. Colver, and P.W. Bowers Guidelines for the management of basal cell carcinoma Br J Dermatol 141 1999 415 423
26. E. Epstein How accurate is the visual assessment of basal cell carcinoma margins? Br J Dermatol 89 1973 37 43
27. B. Essers, C. Dirksen, F. Nieman, N.W. Smeets, G.A. Krekels, and M.H. Prins Cost-effectiveness of surgical excision versus Mohs micrographic surgery for basal cell carcinoma of the face Arch Dermatol 142 2006 187 194