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Chemistry - A European Journal

Volumn 21, Issue 1, 2015, Pages 355-359

Formal total synthesis of (-)-taxol through Pd-catalyzed eight-membered carbocyclic ring formation

(4) Hirai, Sho a Utsugi, Masayuki a Iwamoto, Mitsuhiro a Nakada, Masahisa a

a WASEDA UNIVERSITY (Japan)

Author keywords

Cyclization; Enantioselectivity; Natural products; Palladium; Total synthesis

Indexed keywords

ACETONE; ALKENYLATION; CATALYSIS; ENANTIOSELECTIVITY; KETONES; PALLADIUM; SYNTHESIS (CHEMICAL);

CARBOCYCLIC RING FORMATION; CARBOCYCLIC RINGS; CATALYZED REACTIONS; CONVERGENT APPROACH; CYCLIZED PRODUCTS; NATURAL PRODUCTS; STEREOGENIC CENTERS; TOTAL SYNTHESIS;

CYCLIZATION;

PACLITAXEL; PALLADIUM;

CATALYSIS; CHEMICAL SYNTHESIS; CHEMISTRY; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; MOLECULAR CONFORMATION; STEREOISOMERISM;

CATALYSIS; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; MOLECULAR CONFORMATION; PACLITAXEL; PALLADIUM; STEREOISOMERISM;

EID: 84920452257 PISSN: 09476539 EISSN: 15213765 Source Type: Journal
DOI: 10.1002/chem.201404295 Document Type: Article

Times cited : (56)

References (52)

1
- 0015211527
- M. C. Wani, H. L. Taylor, M. E. Wall, P. Coggon, A. T. McPhail, J. Am. Chem. Soc. 1971, 93, 2325-2327.
- (1971) J. Am. Chem. Soc. , vol.93 , pp. 2325-2327
- Wani, M.C.¹ Taylor, H.L.² Wall, M.E.³ Coggon, P.⁴ McPhail, A.T.⁵

2
- 80155147586
- Y.-F. Wang, Q.-W. Shi, M. Dong, H. Kiyota, Y.-C. Gu, B. Cong, Chem. Rev. 2011, 111, 7652-7709.
- (2011) Chem. Rev. , vol.111 , pp. 7652-7709
- Wang, Y.-F.¹ Shi, Q.-W.² Dong, M.³ Kiyota, H.⁴ Gu, Y.-C.⁵ Cong, B.⁶

3
- 0037139411
- A. K. Singla, A. Garg, D. Aggarwal, Int. J. Pharm. 2002, 235, 179-192.
- (2002) Int. J. Pharm. , vol.235 , pp. 179-192
- Singla, A.K.¹ Garg, A.² Aggarwal, D.³

4
- 33748226949
- K. C. Nicolaou, W. M. Dai, R. K. Guy, Angew. Chem. Int. Ed. Engl. 1994, 33, 15-44;
- (1994) Angew. Chem. Int. Ed. Engl. , vol.33 , pp. 15-44
- Nicolaou, K.C.¹ Dai, W.M.² Guy, R.K.³

5
- 0348107896
- Angew. Chem. 1994, 106, 38-69.
- (1994) Angew. Chem. , vol.106 , pp. 38-69

6
- 65549091982
- For synthetic studies reported within the last five years, see: a) T. Serizawa, S. Miyamoto, Y. Numajiri, S. Fuse, T. Doi, T. Takahashi, Tetrahedron Lett. 2009, 50, 3408-3410;
- (2009) Tetrahedron Lett. , vol.50 , pp. 3408-3410
- Serizawa, T.¹ Miyamoto, S.² Numajiri, Y.³ Fuse, S.⁴ Doi, T.⁵ Takahashi, T.⁶

7
- 67650260766
- b)W. P. D. Goldring, G. Pattenden, S. L. Rimmington, Tetrahedron 2009, 65, 6670-6681;
- (2009) Tetrahedron , vol.65 , pp. 6670-6681
- Goldring, W.P.D.¹ Pattenden, G.² Rimmington, S.L.³

8
- 84856743222
- c) C. Ma, S. Schiltz, J. Prunet, Collect. Czech. Chem. Commun. 2011, 76, 1579-1594;
- (2011) Collect. Czech. Chem. Commun. , vol.76 , pp. 1579-1594
- Ma, C.¹ Schiltz, S.² Prunet, J.³

9
- 79953013344
- d) J. Petrignet, A. Boudhar, G. Blond, J. Suffert, Angew. Chem. Int. Ed. 2011, 50, 3285-3289;
- (2011) Angew. Chem. Int. Ed. , vol.50 , pp. 3285-3289
- Petrignet, J.¹ Boudhar, A.² Blond, G.³ Suffert, J.⁴

10
- 80051995003
- Angew. Chem. 2011, 123, 3343-3347;
- (2011) Angew. Chem. , vol.123 , pp. 3343-3347

11
- 83655183058
- e) A. Mendoza, Y. Ishihara, P. S. Baran, Nat. Chem. 2011, 4, 21-25;
- (2011) Nat. Chem. , vol.4 , pp. 21-25
- Mendoza, A.¹ Ishihara, Y.² Baran, P.S.³

12
- 84897484214
- f) N. C. Wilde, M. Isomura, A. Mendoza, P. S. Baran, J. Am. Chem. Soc. 2014, 136, 4909-4912.
- (2014) J. Am. Chem. Soc. , vol.136 , pp. 4909-4912
- Wilde, N.C.¹ Isomura, M.² Mendoza, A.³ Baran, P.S.⁴

13
- 0028213668
- a) R. A. Holton, C. Somoza, H.-B. Kim, F. Liang, R. J. Biediger, P. D. Boatman, M. Shindo, C. C. Smith, S. Kim, H. Nadizadeh, Y. Suzuki, C. Tao, P. Vu, S. Tang, P. Zhang, K. K. Murthi, L. N. Gentile, J. H. Liu, J. Am. Chem. Soc. 1994, 116, 1597-1598;
- (1994) J. Am. Chem. Soc. , vol.116 , pp. 1597-1598
- Holton, R.A.¹ Somoza, C.² Kim, H.-B.³ Liang, F.⁴ Biediger, R.J.⁵ Boatman, P.D.⁶ Shindo, M.⁷ Smith, C.C.⁸ Kim, S.⁹ Nadizadeh, H.¹⁰ Suzuki, Y.¹¹ Tao, C.¹² Vu, P.¹³ Tang, S.¹⁴ Zhang, P.¹⁵ Murthi, K.K.¹⁶ Gentile, L.N.¹⁷ Liu, J.H.¹⁸

14
- 0028353983
- b) R. A. Holton, H. B. Kim, C. Somoza, F. Liang, R. J. Biediger, P. D. Boatman, M. Shindo, C. C. Smith, S. Kim, H. Nadizadeh, Y. Suzuki, C. Tao, P. Vu, S. Tang, P. Zhang, K. K. Murthi, L. N. Gentile, J. H. Liu, J. Am. Chem. Soc. 1994, 116, 1599-1600.
- (1994) J. Am. Chem. Soc. , vol.116 , pp. 1599-1600
- Holton, R.A.¹ Kim, H.B.² Somoza, C.³ Liang, F.⁴ Biediger, R.J.⁵ Boatman, P.D.⁶ Shindo, M.⁷ Smith, C.C.⁸ Kim, S.⁹ Nadizadeh, H.¹⁰ Suzuki, Y.¹¹ Tao, C.¹² Vu, P.¹³ Tang, S.¹⁴ Zhang, P.¹⁵ Murthi, K.K.¹⁶ Gentile, L.N.¹⁷ Liu, J.H.¹⁸

15
- 0028012837
- a) K. C. Nicolaou, Z. Yang, J. J. Liu, H. Ueno, P. G. Nantermet, R. K. Guy, C. F. Claiborne, J. Renaud, E. A. Couladouros, K. Paulvannan, E. J. Sorensen, Nature 1994, 367, 630-634;
- (1994) Nature , vol.367 , pp. 630-634
- Nicolaou, K.C.¹ Yang, Z.² Liu, J.J.³ Ueno, H.⁴ Nantermet, P.G.⁵ Guy, R.K.⁶ Claiborne, C.F.⁷ Renaud, J.⁸ Couladouros, E.A.⁹ Paulvannan, K.¹⁰ Sorensen, E.J.¹¹

16
- 0028810338
- b) K. C. Nicolaou, P. G. Nantermet, H. Ueno, R. K. Guy, E. A. Couladouros, E. J. Sorensen, J. Am. Chem. Soc. 1995, 117, 624-633;
- (1995) J. Am. Chem. Soc. , vol.117 , pp. 624-633
- Nicolaou, K.C.¹ Nantermet, P.G.² Ueno, H.³ Guy, R.K.⁴ Couladouros, E.A.⁵ Sorensen, E.J.⁶

17
- 0028792481
- c) K. C. Nicolaou, J.-J. Liu, Z. Yang, H. Ueno, E. J. Sorensen, C. F. Claiborne, R. K. Guy, C.-K. Hwang, M. Nakada, P. G. Nantermet, J. Am. Chem. Soc. 1995, 117, 634-644;
- (1995) J. Am. Chem. Soc. , vol.117 , pp. 634-644
- Nicolaou, K.C.¹ Liu, J.-J.² Yang, Z.³ Ueno, H.⁴ Sorensen, E.J.⁵ Claiborne, C.F.⁶ Guy, R.K.⁷ Hwang, C.-K.⁸ Nakada, M.⁹ Nantermet, P.G.¹⁰

18
- 0028849334
- d) K. C. Nicolaou, Z. Yang, J.-J. Liu, P. G. Nantermet, C. F. Claiborne, J. Renaud, R. K. Guy, K. Shibayama, J. Am. Chem. Soc. 1995, 117, 645-652;
- (1995) J. Am. Chem. Soc. , vol.117 , pp. 645-652
- Nicolaou, K.C.¹ Yang, Z.² Liu, J.-J.³ Nantermet, P.G.⁴ Claiborne, C.F.⁵ Renaud, J.⁶ Guy, R.K.⁷ Shibayama, K.⁸

19
- 0028868994
- e) K. C. Nicolaou, H. Ueno, J.-J. Liu, P. G. Nantermet, Z. Yang, J. Renaud, K. Paulvannan, R. Chadha, J. Am. Chem. Soc. 1995, 117, 653-659.
- (1995) J. Am. Chem. Soc. , vol.117 , pp. 653-659
- Nicolaou, K.C.¹ Ueno, H.² Liu, J.-J.³ Nantermet, P.G.⁴ Yang, Z.⁵ Renaud, J.⁶ Paulvannan, K.⁷ Chadha, R.⁸

20
- 33748237378
- a) J. J. Masters, J. T. Link, L. B. Snyder, W. B. Young, S. J. Danishefsky, Angew. Chem. Int. Ed. Engl. 1995, 34, 1723-1726;
- (1995) Angew. Chem. Int. Ed. Engl. , vol.34 , pp. 1723-1726
- Masters, J.J.¹ Link, J.T.² Snyder, L.B.³ Young, W.B.⁴ Danishefsky, S.J.⁵

21
- 0000903348
- Angew. Chem. 1995, 107, 1886-1888;
- (1995) Angew. Chem. , vol.107 , pp. 1886-1888

22
- 11044223276
- b) S. J. Danishefsky, J. J. Masters, W. B. Young, J. T. Link, L. B. Snyder, T. V. Magee, D. K. Jung, R. C. A. Isaacs, W. G. Bornmann, C. A. Alaimo, C. A. Coburn, M. J. D. Grandi, J. Am. Chem. Soc. 1996, 118, 2843-2859.
- (1996) J. Am. Chem. Soc. , vol.118 , pp. 2843-2859
- Danishefsky, S.J.¹ Masters, J.J.² Young, W.B.³ Link, J.T.⁴ Snyder, L.B.⁵ Magee, T.V.⁶ Jung, D.K.⁷ Isaacs, R.C.A.⁸ Bornmann, W.G.⁹ Alaimo, C.A.¹⁰ Coburn, C.A.¹¹ Grandi, M.J.D.¹²

23
- 0030889501
- a) P. A. Wender, N. F. Badham, S. P. Conway, P. E. Floreancig, T. E. Glass, C. Gränicher, J. B. Houze, J. Jänichen, D. Lee, D. G. Marquess, P. L. McGrane, W. Meng, T. P. Mucciaro, M. Mühlebach, M. G. Natchus, H. Paulsen, D. B. Rawlins, J. Satkofsky, A. J. Shuker, J. C. Sutton, R. E. Taylor, K. Tomooka, J. Am. Chem. Soc. 1997, 119, 2755-2756;
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 2755-2756
- Wender, P.A.¹ Badham, N.F.² Conway, S.P.³ Floreancig, P.E.⁴ Glass, T.E.⁵ Gränicher, C.⁶ Houze, J.B.⁷ Jänichen, J.⁸ Lee, D.⁹ Marquess, D.G.¹⁰ McGrane, P.L.¹¹ Meng, W.¹² Mucciaro, T.P.¹³ Mühlebach, M.¹⁴ Natchus, M.G.¹⁵ Paulsen, H.¹⁶ Rawlins, D.B.¹⁷ Satkofsky, J.¹⁸ Shuker, A.J.¹⁹ Sutton, J.C.²⁰ Taylor, R.E.²¹ Tomooka, K.²² more..

24
- 0030936927
- b) P. A. Wender, N. F. Badham, S. P. Conway, P. E. Floreancig, T. E. Glass, J. B. Houze, N. E. Krauss, D. S. Lee, D. G. Marquess, P. L. McGrane, W. Meng, M. G. Natchus, A. J. Shuker, J. C. Sutton, R. E. Taylor, J. Am. Chem. Soc. 1997, 119, 2757-2758.
- (1997) J. Am. Chem. Soc. , vol.119 , pp. 2757-2758
- Wender, P.A.¹ Badham, N.F.² Conway, S.P.³ Floreancig, P.E.⁴ Glass, T.E.⁵ Houze, J.B.⁶ Krauss, N.E.⁷ Lee, D.S.⁸ Marquess, D.G.⁹ McGrane, P.L.¹⁰ Meng, W.¹¹ Natchus, M.G.¹² Shuker, A.J.¹³ Sutton, J.C.¹⁴ Taylor, R.E.¹⁵

25
- 0010375957
- a) T. Mukaiyama, I. Shiina, H. Iwadare, H. Sakoh, Y. Tani, M. Hasegawa, K. Saitoh, Proc. Jpn. Acad. Ser. B 1997, 73, 95-100;
- (1997) Proc. Jpn. Acad. Ser. B , vol.73 , pp. 95-100
- Mukaiyama, T.¹ Shiina, I.² Iwadare, H.³ Sakoh, H.⁴ Tani, Y.⁵ Hasegawa, M.⁶ Saitoh, K.⁷

26
- 0032959568
- b) T. Mukaiyama, I. Shiina, H. Iwadare, M. Saitoh, T. Nishimura, N. Ohkawa, H. Sakoh, K. Nishimura, Y. Tani, M. Hasegawa, K. Yamada, K. Saitoh, Chem. Eur. J. 1999, 5, 121-161.
- (1999) Chem. Eur. J. , vol.5 , pp. 121-161
- Mukaiyama, T.¹ Shiina, I.² Iwadare, H.³ Saitoh, M.⁴ Nishimura, T.⁵ Ohkawa, N.⁶ Sakoh, H.⁷ Nishimura, K.⁸ Tani, Y.⁹ Hasegawa, M.¹⁰ Yamada, K.¹¹ Saitoh, K.¹²

27
- 0032539249
- a) K. Morihira, R. Hara, S. Kawahara, T. Nishimori, N. Nakamura, H. Kusama, I. Kuwajima, J. Am. Chem. Soc. 1998, 120, 12980-12981;
- (1998) J. Am. Chem. Soc. , vol.120 , pp. 12980-12981
- Morihira, K.¹ Hara, R.² Kawahara, S.³ Nishimori, T.⁴ Nakamura, N.⁵ Kusama, H.⁶ Kuwajima, I.⁷

28
- 0034716749
- b) H. Kusama, R. Hara, S. Kawahara, T. Nishimori, H. Kashima, N. Nakamura, K. Morihira, I. Kuwajima, J. Am. Chem. Soc. 2000, 122, 3811-3820.
- (2000) J. Am. Chem. Soc. , vol.122 , pp. 3811-3820
- Kusama, H.¹ Hara, R.² Kawahara, S.³ Nishimori, T.⁴ Kashima, H.⁵ Nakamura, N.⁶ Morihira, K.⁷ Kuwajima, I.⁸

29
- 33749182636
- T. Doi, S. Fuse, S. Miyamoto, K. Nakai, D. Sasuga, T. Takahashi, Chem. Asian J. 2006, 1, 370-383.
- (2006) Chem. Asian J. , vol.1 , pp. 370-383
- Doi, T.¹ Fuse, S.² Miyamoto, S.³ Nakai, K.⁴ Sasuga, D.⁵ Takahashi, T.⁶

30
- 0032518888
- a) M. Nakada, E. Kojima, Y. Iwata, Tetrahedron Lett. 1998, 39, 313-316;
- (1998) Tetrahedron Lett. , vol.39 , pp. 313-316
- Nakada, M.¹ Kojima, E.² Iwata, Y.³

31
- 0041379817
- b) M. Iwamoto, H. Kawada, T. Tanaka, M. Nakada, Tetrahedron Lett. 2003, 44, 7239-7243;
- (2003) Tetrahedron Lett. , vol.44 , pp. 7239-7243
- Iwamoto, M.¹ Kawada, H.² Tanaka, T.³ Nakada, M.⁴

32
- 10044244963
- c) H. Kawada, M. Iwamoto, M. Utsugi, M. Miyano, M. Nakada, Org. Lett. 2004, 6, 4491-4494;
- (2004) Org. Lett. , vol.6 , pp. 4491-4494
- Kawada, H.¹ Iwamoto, M.² Utsugi, M.³ Miyano, M.⁴ Nakada, M.⁵

33
- 7044222313
- d) M. Iwamoto, M. Miyano, M. Utsugi, H. Kawada, M. Nakada, Tetrahedron Lett. 2004, 45, 8647-8651;
- (2004) Tetrahedron Lett. , vol.45 , pp. 8647-8651
- Iwamoto, M.¹ Miyano, M.² Utsugi, M.³ Kawada, H.⁴ Nakada, M.⁵

34
- 7044231370
- e) M. Iwamoto, M. Miyano, M. Utsugi, H. Kawada, M. Nakada, Tetrahedron Lett. 2004, 45, 8653-8657;
- (2004) Tetrahedron Lett. , vol.45 , pp. 8653-8657
- Iwamoto, M.¹ Miyano, M.² Utsugi, M.³ Kawada, H.⁴ Nakada, M.⁵

35
- 33746601340
- f) M. Utsugi, M. Miyano, M. Nakada, Org. Lett. 2006, 8, 2973-2976;
- (2006) Org. Lett. , vol.8 , pp. 2973-2976
- Utsugi, M.¹ Miyano, M.² Nakada, M.³

36
- 34548203217
- g) M. Utsugi, Y. Kamada, H. Miyamoto, M. Nakada, Tetrahedron Lett. 2007, 48, 6868-6872;
- (2007) Tetrahedron Lett. , vol.48 , pp. 6868-6872
- Utsugi, M.¹ Kamada, Y.² Miyamoto, H.³ Nakada, M.⁴

37
- 45649083168
- h) M. Utsugi, Y. Kamada, H. Miyamoto, M. Nakada, Tetrahedron Lett. 2008, 49, 4754-4757;
- (2008) Tetrahedron Lett. , vol.49 , pp. 4754-4757
- Utsugi, M.¹ Kamada, Y.² Miyamoto, H.³ Nakada, M.⁴

38
- 84875227986
- i) S. Hirai, N. Urushizako, M. Miyano, T. Fujii, M. Nakada, Tetrahedron Lett. 2013, 54, 1888-1892.
- (2013) Tetrahedron Lett. , vol.54 , pp. 1888-1892
- Hirai, S.¹ Urushizako, N.² Miyano, M.³ Fujii, T.⁴ Nakada, M.⁵

39
- 82255193951
- K. Tsuna, N. Noguchi, M. Nakada, Tetrahedron Lett. 2011, 52, 7202-7205.
- (2011) Tetrahedron Lett. , vol.52 , pp. 7202-7205
- Tsuna, K.¹ Noguchi, N.² Nakada, M.³

40
- 20344385760
- H. Watanabe, M. Iwamoto, M. Nakada, J. Org. Chem. 2005, 70, 4652-4658.
- (2005) J. Org. Chem. , vol.70 , pp. 4652-4658
- Watanabe, H.¹ Iwamoto, M.² Nakada, M.³

41
- 0002464862
- a) K. B. Sharpless, T. R. Verhoeven, Aldrichimica Acta 1979, 12, 63-74;
- (1979) Aldrichimica Acta , vol.12 , pp. 63-74
- Sharpless, K.B.¹ Verhoeven, T.R.²

42
- 0000458209
- b) A. H. Hoveyda, D. A. Evans, G. C. Fu, Chem. Rev. 1993, 93, 1307-1370;
- (1993) Chem. Rev. , vol.93 , pp. 1307-1370
- Hoveyda, A.H.¹ Evans, D.A.² Fu, G.C.³

43
- 33746217394
- c) K. C. Nicolaou, S. T. Harrison, Angew. Chem. Int. Ed. 2006, 45, 3256-3260;
- (2006) Angew. Chem. Int. Ed. , vol.45 , pp. 3256-3260
- Nicolaou, K.C.¹ Harrison, S.T.²

44
- 33748552666
- Angew. Chem. 2006, 118, 3334-3338.
- (2006) Angew. Chem. , vol.118 , pp. 3334-3338

45
- 0001234205
- a) R. O. Hutchins, I. M. Taffer, W. Burgoyne, J. Org. Chem. 1981, 46, 5214-5215;
- (1981) J. Org. Chem. , vol.46 , pp. 5214-5215
- Hutchins, R.O.¹ Taffer, I.M.² Burgoyne, W.³

46
- 33751157676
- b) D. F. Taber, J. B. Houze, J. Org. Chem. 1994, 59, 4004-4006.
- (1994) J. Org. Chem. , vol.59 , pp. 4004-4006
- Taber, D.F.¹ Houze, J.B.²

47
- 0001705553
- a) F. A. Davis, J. Lamendola Jr., U. Nadir, E. W. Kluger, T. C. Swdergran, T. W. Panunt, R. Billmers, R. Jenkins Jr., I. J. Turchi, W. H. Watson, J. S. Chen, M. Kimura, J. Am. Chem. Soc. 1980, 102, 2000-2005;
- (1980) J. Am. Chem. Soc. , vol.102 , pp. 2000-2005
- Davis, F.A.¹ Lamendola, J.² Nadir, U.³ Kluger, E.W.⁴ Swdergran, T.C.⁵ Panunt, T.W.⁶ Billmers, R.⁷ Jenkins, R.⁸ Turchi, I.J.⁹ Watson, W.H.¹⁰ Chen, J.S.¹¹ Kimura, M.¹²

48
- 0000886888
- b) F. A. Davis, S. Dayay, J. C. Towson, S. Lal, T. Reddy, J. Org. Chem. 1988, 53, 2087-2089.
- (1988) J. Org. Chem. , vol.53 , pp. 2087-2089
- Davis, F.A.¹ Dayay, S.² Towson, J.C.³ Lal, S.⁴ Reddy, T.⁵

49
- 0030013712
- R. Miller, W. Li, R. Humphrey, Tetrahedron Lett. 1996, 37, 3429-3432.
- (1996) Tetrahedron Lett. , vol.37 , pp. 3429-3432
- Miller, R.¹ Li, W.² Humphrey, R.³

50
- 0033607444
- a) M. Adinolfi, G. Barone, L. Guariniello, A. Iadonisi, Tetrahedron Lett. 1999, 40, 8439-8441;
- (1999) Tetrahedron Lett. , vol.40 , pp. 8439-8441
- Adinolfi, M.¹ Barone, G.² Guariniello, L.³ Iadonisi, A.⁴

51
- 33846227533
- b) P. M. Senthilkumar, A. Aravind, S. Baskaran, Tetrahedron Lett. 2007, 48, 1175-1178;
- (2007) Tetrahedron Lett. , vol.48 , pp. 1175-1178
- Senthilkumar, P.M.¹ Aravind, A.² Baskaran, S.³

52
- 37049092006
- c) H.-P. Wessel, D. R. Bundle, J. Chem. Soc. Perkin Trans. 1 1985, 2251-2260.
- (1985) J. Chem. Soc. Perkin Trans. , vol.1 , pp. 2251-2260
- Wessel, H.-P.¹ Bundle, D.R.²

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