MBL2 deficiency is associated with higher genomic bacterial loads during meningococcemia in young children

Clinical Microbiology and Infection

Volumn 20, Issue 12, 2014, Pages 1337-1342

  Darton, T C ^a,b,f   Jack, D L ^b   Johnson, M ^c   Borrow, R ^d   Guiver, M ^d   Kaczmarski, E B ^d   Turner, M W ^c   Klein, N J ^c   Read, R C ^e  

^a ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF SHEFFIELD   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d PUBLIC HEALTH ENGLAND   (United Kingdom)

^e UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^f UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Genomic bacterial load; Gram negative sepsis; Mannose binding lectin; Meningococcal infection; Neisseria meningitidis

Indexed keywords

MANNOSE BINDING LECTIN 2; MANNOSE BINDING LECTIN;

ADAPTIVE IMMUNITY; ADOLESCENT; AGE; ARTICLE; BACTERIAL GENOME; BACTERIAL LOAD; BLOOD SAMPLING; CHILD; CHILD HEALTH; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENOTYPE; HOSPITAL ADMISSION; HUMAN; INFECTION SENSITIVITY; INNATE IMMUNITY; MAJOR CLINICAL STUDY; MALE; MANNOSE BINDING LECTIN 2 DEFICIENCY; MENINGOCOCCEMIA; MULTIPLEX POLYMERASE CHAIN REACTION; NEISSERIA MENINGITIDIS; PRIORITY JOURNAL; PROTEIN DEFICIENCY; BACTEREMIA; BLOOD; DEFICIENCY; DISEASE PREDISPOSITION; GENETICS; GENOTYPING TECHNIQUE; IMMUNOLOGY; INBORN ERROR OF METABOLISM; INFANT; ISOLATION AND PURIFICATION; MENINGOCOCCOSIS; MICROBIOLOGY; PRESCHOOL CHILD;

BACTERIA (MICROORGANISMS); NEGIBACTERIA; NEISSERIA MENINGITIDIS;

ADOLESCENT; BACTEREMIA; BACTERIAL LOAD; BLOOD; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DISEASE SUSCEPTIBILITY; FEMALE; GENOTYPE; GENOTYPING TECHNIQUES; HUMANS; INFANT; MALE; MANNOSE-BINDING LECTIN; MENINGOCOCCAL INFECTIONS; METABOLISM, INBORN ERRORS; NEISSERIA MENINGITIDIS;

EID: 84920366932     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/1469-0691.12745     Document Type: Article

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