Postnatal growth of the human pons: A morphometric and immunohistochemical analysis

Journal of Comparative Neurology

Volumn 523, Issue 3, 2015, Pages 449-462

  Tate, Matthew C ^a,b   Lindquist, Robert A ^a,b   Nguyen, Thuhien ^a,b   Sanai, Nader ^c   Barkovich, A James ^b   Huang, Eric J ^a,b   Rowitch, David H ^a,b   Alvarez Buylla, Arturo ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c BARROW NEUROLOGICAL INSTITUTE   (United States)

Author keywords

AB_2109815; AB_2304493; AB_2336877; AB_2336878; AB_261856; AB_291466; AB_304558; AB_396287; AB_442102; AB_91107; AB_92396; Basis; Brainstem; Development; Nif 0000 00217; Pediatric; Pontine glioma; SciRes_000114

Indexed keywords

MYELIN BASIC PROTEIN; NESTIN; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; VIMENTIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; KI 67 ANTIGEN; NERVE PROTEIN; OLIG2 PROTEIN, HUMAN;

ADOLESCENT; ADULT; ARTICLE; CELL DENSITY; CELL PROLIFERATION; CHILD; CONTROLLED STUDY; DEVELOPMENTAL STAGE; FEMALE; GROWTH RATE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFANT; MALE; MEDULLA OBLONGATA; MORPHOMETRICS; MYELINATION; NEWBORN; OLIGODENDROGLIA; PONS; POSTNATAL GROWTH; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SCHOOL CHILD; TEGMENTUM; ANALYSIS OF VARIANCE; ANATOMY AND HISTOLOGY; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MYELIN SHEATH; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSIOLOGY;

ADOLESCENT; ANALYSIS OF VARIANCE; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL PROLIFERATION; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; KI-67 ANTIGEN; MAGNETIC RESONANCE IMAGING; MALE; MYELIN SHEATH; NERVE TISSUE PROTEINS; PONS;

EID: 84920287280     PISSN: 00219967     EISSN: 10969861     Source Type: Journal    
DOI: 10.1002/cne.23690     Document Type: Article

References (32)

1. Abe S, Takagi K, Yamamoto T, Okuhata Y, Kato T. 2004. Semiquantitative assessment of myelination using magnetic resonance imaging in normal fetal brains. Prenat Diagn 24:352-357.
2. Adams CE, Parnavelas JG, Mihailoff GA, Woodward DJ. 1980. The neurons and their postnatal development in the basilar pontine nuclei of the rat. Brain Res Bull 5:277-283.
3. Ballester LY, Wang Z, Shandilya S, Miettinen M, Burger PC, Eberhart CG, Rodriguez FJ, Raabe E, Nazarian J, Warren K, Quezado MM. 2013. Morphologic characteristics and immunohistochemical profile of diffuse intrinsic pontine gliomas. Am J Surg Pathol 37:1357-1364.
4. Barkovich AJ, Millen KJ, Dobyns WB. 2009. A developmental and genetic classification for midbrain-hindbrain malformations. Brain 132(Pt 12):3199-3230.
5. Barrow J, Adamowicz-Brice M, Cartmill M, MacArthur D, Lowe J, Robson K, Brundler MA, Walker DA, Coyle B, Grundy R. 2011. Homozygous loss of ADAM3A revealed by genome-wide analysis of pediatric high-grade glioma and diffuse intrinsic pontine gliomas. Neuro Oncol 13:212-222.
6. Bohn W, Wiegers W, Beuttenmuller M, Traub P. 1992. Species-specific recognition patterns of monoclonal antibodies directed against vimentin. Exp Cell Res 201:1-7.
7. Brody BA, Kinney HC, Kloman AS, Gilles FH. 1987. Sequence of central nervous system myelination in human infancy. I. An autopsy study of myelination. J Neuropathol Exp Neurol 46:283-301.
8. Debus E, Weber K, Osborn M. 1983. Monoclonal antibodies specific for glial fibrillary acidic (GFA) protein and for each of the neurofilament triplet polypeptides. Differentiation 25:193-203.
9. Essick CR. 1912. The development of the nuclei pontis and the nucleus arcuatus in man. Am J Anat 13:25-54.
10. Fangusaro J. 2009. Pediatric high-grade gliomas and diffuse intrinsic pontine gliomas. J Child Neurol 24:1409-1417.
11. Fischbein NJ, Prados MD, Wara W, Russo C, Edwards MS, Barkovich AJ. 1996. Radiologic classification of brain stem tumors: correlation of magnetic resonance imaging appearance with clinical outcome. Pediatr Neurosurg 24:9-23.
12. Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ. 2010. Subtypes of medulloblastoma have distinct developmental origins. Nature 468:1095-1099.
13. Grill J, Puget S, Andreiuolo F, Philippe C, MacConaill L, Kieran MW. 2012. Critical oncogenic mutations in newly diagnosed pediatric diffuse intrinsic pontine glioma. Pediatr Blood Cancer 58:489-491.
14. Hatta T, Satow F, Hatta J, Hashimoto R, Udagawa J, Matsumoto A, Otani H. 2007. Development of the pons in human fetuses. Congenit Anom (Kyoto) 47:63-67.
15. Kinney HC, Brody BA, Kloman AS, Gilles FH. 1988. Sequence of central nervous system myelination in human infancy. II. Patterns of myelination in autopsied infants. J Neuropathol Exp Neurol 47:217-234.
16. Ligon KL, Alberta JA, Kho AT, Weiss J, Kwaan MR, Nutt CL, Louis DN, Stiles CD, Rowitch DH. 2004. The oligodendroglial lineage marker OLIG2 is universally expressed in diffuse gliomas. J Neuropathol Exp Neurol 63:499-509.
17. Ligon KL, Kesari S, Kitada M, Sun T, Arnett HA, Alberta JA, Anderson DJ, Stiles CD, Rowitch DH. 2006. Development of NG2 neural progenitor cells requires Olig gene function. Proc Natl Acad Sci U S A 103:7853-7858.
18. Messam CA, Hou J, Major EO. 2000. Coexpression of nestin in neural and glial cells in the developing human CNS defined by a human-specific anti-nestin antibody. Exp Neurol 161:585-596.
19. Mihailoff GA, Adams CE, Woodward DJ. 1984. An autoradiographic study of the postnatal development of sensorimotor and visual components of the corticopontine system. J Comp Neurol 222:116-127.
20. Monje M, Mitra SS, Freret ME, Raveh TB, Kim J, Masek M, Attema JL, Li G, Haddix T, Edwards MS, Fisher PG, Weissman IL, Rowitch DH, Vogel H, Wong AJ, Beachy PA. 2011. Hedgehog-responsive candidate cell of origin for diffuse intrinsic pontine glioma. Proc Natl Acad Sci U S A 108:4453-4458.
21. Nozaki H, Goto N, Nara T. 1992. Development of the human pontine nuclei: a morphometric study. Brain Res Dev Brain Res 65:13-20.
22. Paugh BS, Broniscer A, Qu C, Miller CP, Zhang J, Tatevossian RG, Olson JM, Geyer JR, Chi SN, da Silva NS, Onar-Thomas A, Baker JN, Gajjar A, Ellison DW, Baker SJ. 2011. Genome-wide analyses identify recurrent amplifications of receptor tyearosine kinases and cell-cycle regulatory genes in diffuse intrinsic pontine glioma. J Clin Oncol 29:3999-4006.
23. Puget S, Philippe C, Bax DA, Job B, Varlet P, Junier MP, Andreiuolo F, Carvalho D, Reis R, Guerrini-Rousseau L, Roujeau T, Dessen P, Richon C, Lazar V, Le Teuff G, Sainte-Rose C, Geoerger B, Vassal G, Jones C, Grill J. 2012. Mesenchymal transition and PDGFRA amplification/mutation are key distinct oncogenic events in pediatric diffuse intrinsic pontine gliomas. PLoS One 7:e30313.
24. Quinones-Hinojosa A, Sanai N, Soriano-Navarro M, Gonzalez-Perez O, Mirzadeh Z, Gil-Perotin S, Romero-Rodriguez R, Berger MS, Garcia-Verdugo JM, Alvarez-Buylla A. 2006. Cellular composition and cytoarchitecture of the adult human subventricular zone: a niche of neural stem cells. J Comp Neurol 494:415-434.
25. Roig B, Franco-Pons N, Martorell L, Tomas J, Vogel WF, Vilella E. 2010. Expression of the tyrosine kinase discoidin domain receptor 1 (DDR1) in human central nervous system myelin. Brain Res 1336:22-29.
26. Saladin KS. 2012. Anatomy & physiology: the unity of form and function. New York: McGraw-Hill.
27. Schuller U, Heine VM, Mao J, Kho AT, Dillon AK, Han YG, Huillard E, Sun T, Ligon AH, Qian Y, Ma Q, Alvarez-Buylla A, McMahon AP, Rowitch DH, Ligon KL. 2008. Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma. Cancer Cell 14:123-134.
28. Stathopoulos E, Naeve GS, Taylor CR, Epstein AL. 1989. LN-6: a monoclonal antibody to vimentin expressed in non-hematopoietic mesenchymal cells and derived tumors and reactive in B5-fixed, paraffin-embedded tissues. J Histochem Cytochem 37:1363-1370.
29. Taylor MD, Poppleton H, Fuller C, Su X, Liu Y, Jensen P, Magdaleno S, Dalton J, Calabrese C, Board J, Macdonald T, Rutka J, Guha A, Gajjar A, Curran T, Gilbertson RJ. 2005. Radial glia cells are candidate stem cells of ependymoma. Cancer Cell 8:323-335.
30. Wagner S, Warmuth-Metz M, Emser A, Gnekow AK, Strater R, Rutkowski S, Jorch N, Schmid HJ, Berthold F, Graf N, Kortmann RD, Pietsch T, Sorensen N, Peters O, Wolff JE. 2006. Treatment options in childhood pontine gliomas. J Neurooncol 79:281-287.
31. Wu G, Broniscer A, McEachron TA, Lu C, Paugh BS, Becksfort J, Qu C, Ding L, Huether R, Parker M, Zhang J, Gajjar A, Dyer MA, Mullighan CG, Gilbertson RJ, Mardis ER, Wilson RK, Downing JR, Ellison DW, Baker SJ. 2012. Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas. Nat Genet 44:251-253.
32. Zarghooni M, Bartels U, Lee E, Buczkowicz P, Morrison A, Huang A, Bouffet E, Hawkins C. 2010. Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor alpha and poly (ADP-ribose) polymerase as potential therapeutic targets. J Clin Oncol 28:1337-1344.