Relationship of semen hyperviscosity with IL-6, TNF-α, IL-10 and ROS production in seminal plasma of infertile patients with prostatitis and prostato-vesiculitis

Andrologia

Volumn 46, Issue 10, 2014, Pages 1148-1155

  Castiglione, R ^a   Salemi, M ^b   Vicari, L O ^a   Vicari, E ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b OASI RESEARCH INSTITUTE IRCCS   (Italy)

Author keywords

Infections; Prostatitis; Reactive oxygen species; Semen cytokine; Semen hyperviscosity

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 6; REACTIVE OXYGEN METABOLITE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; HUMAN; LEUKOCYTE; MALE; MALE INFERTILITY; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY; PROSTATITIS; SEMINAL VESICLE; SPERM; SPERMATOZOON COUNT; VISCOSITY;

ADULT; HUMANS; INFERTILITY, MALE; INTERLEUKIN-10; INTERLEUKIN-6; LEUKOCYTES; MALE; OXIDATIVE STRESS; PROSTATITIS; REACTIVE OXYGEN SPECIES; SEMEN; SEMINAL VESICLES; SPERM COUNT; TUMOR NECROSIS FACTOR-ALPHA; VISCOSITY;

EID: 84920273042     PISSN: 03034569     EISSN: 14390272     Source Type: Journal    
DOI: 10.1111/and.12207     Document Type: Article

References (33)

1. Andrade-Rocha FT (2005) Physical analysis of ejaculate to evaluate the secretory activity of the seminal vesicles and prostate. Clin Chem Lab Med 43:1203-1210.
2. Aydemir B, Onaran I, Kiziler AR, Alici B, Akyolcu MC (2008) The influence of oxidative damage on viscosity of seminal fluid in infertile men. J Androl 29:41-46.
3. Bird RB, Armstrong RC, Hassager O (1987) Dynamics of Polymeric Liquids. Wiley Interscience, New York.
4. Buch JP, Kolon TF, Maulik N, Kreutzer DL, Das DK (1994) Cytokines stimulate lipid membrane peroxidation of human sperm. Fertil Steril 62:186-188.
5. Carpino A, Siciliano L (1998) Unaltered protein pattern/genital tract secretion marker levels in seminal plasma of highly viscous human ejaculates. Arch Androl 41:31-35.
6. Du Plessis SS, Gokul S, Agarwal A (2013) Semen hyperviscosity: causes, consequences, and cures. Front Biosci (Elite Ed) 5:224-231.
7. Elia J, Delfino M, Imbrogno N, Capogreco F, Lucarelli M, Rossi T, Mazzilli F (2009) Human semen hyperviscosity: prevalence, pathogenesis and therapeutic aspects. Asian J Androl 11:609-615.
8. Elzanaty S, Malm J, Giwercman A (2004) Visco-elasticity of seminal fluid in relation to the epididymal and accessory sex gland function and its impact on sperm motility. Int J Androl 27:94-100.
9. Esfandiari N, Burjaq H, Gotlieb L, Casper RF (2008) Seminal hyperviscosity is associated with poor outcome of in vitro fertilization and embryo transfer: a prospective study. Fertil Steril 90:1739-1743.
10. Fraczek M, Kurpisz M (2007) Inflammatory mediators exert toxic effects of oxidative stress on human spermatozoa. J Androl 28:325-333.
11. Gonzales GF (2001) Function of seminal vesicles and their role on male fertility. Asian J Androl 3:251-258.
12. Gonzalez-Estrella JA, Coney P, Ostash K, Karabinus D (1994) Dithiothreitol effects on the viscosity and quality of human semen. Fertil Steril 62:1238-1243.
13. Krausz C, West K, Buckingham D, Aitken RJ (1992) Development of a technique for monitoring the contamination of human semen samples with leukocytes. Fertil Steril 57:1317-1325.
14. La Vignera S, Calogero AE, Castiglione R, D'Agata R, Giammusso B, Condorelli R, Vicari E (2008) IL-6, TNFalfa, IL-10 in the seminal plasma of patients with bacterial male accessory gland infections after sequential therapy. Minerva Urol Nefrol 60:141-145.
15. La Vignera S, Condorelli RA, Vicari E, D'Agata R, Salemi M, Calogero AE (2012) Hyperviscosity of semen in patients with male accessory gland infection:direct measurement with quantitative viscosimeter. Andrologia 44(Suppl 1):556-561.
16. Lanzafame FM, La Vignera S, Vicari E, Calogero AE (2009) Oxidative stress and medical antioxidant treatment in male infertility. Reprod Biomed Online 19:638-659.
17. Matalliotakis I, Arici A, Goumenou A, Koumantakis G, Selam B, Matalliotakis G, Koumantakis E (2002) Distinct expression pattern of cytokines in semen of men with genital infection and oligo-terato-asthenozoospermia. Am J Reprod Immunol 48:170-175.
18. Moulik S, Gopalkrishnan K, Hinduja I, Shahani SK (1989) Presence of sperm antibodies and association with viscosity of semen. Hum Reprod 4:290-291.
19. Munuce MJ, Bregni C, Carizza C, Mendeluk G (1999) Semen culture, leukocytospermia, and the presence of sperm antibodies in seminal hyperviscosity. Arch Androl 42:21-28.
20. Patterson CC, Smith AE, Yarnell JW, Rumley A, Ben-Shlomo Y, Lowe GD (2010) The associations of interleukin-6 (IL-6) and downstream inflammatory markers with risk of cardiovascular disease: the Caerphilly Study. Atherosclerosis 209:551-557.
21. Potts JM, Sharma R, Pasqualotto F, Nelson D, Hall G, Agarwal A (2000) Association of ureaplasma urealyticum with abnormal reactive oxygen species levels and absence of leukocytospermia. J Urol 163:1775-1778.
22. Sanocka D, Fraczek M, Jedrzejczak P, Szumala-Kakol A, Kurpisz M (2004) Male genital tract infection: an influence of leukocytes and bacteria on semen. J Reprod Immunol 62:111-124.
23. Siciliano L, Tarantino P, Longobardi F, Rago V, De Stefano C, Carpino A (2001) Impaired seminal antioxidant capacity in human semen with hyperviscosity or oligoasthenozoospermia. J Androl 22:798-803.
24. Tremellen K (2008) Oxidative stress and male infertility - a clinical perspective. Hum Reprod Update 14:243-258.
25. Vicari E (1999) Seminal leukocyte concentration and related specific reactive oxygen species production in patients with male accessory gland infections. Hum Reprod 14:2025-2030.
26. Vicari E (2000) Effectiveness and limits of antimicrobial treatment on seminal leukocyte concentration and related reactive oxygen species production in patients with male accessory gland infection. Hum Reprod 15:2536-2544.
27. Vicari E, Mongioì A, Speciale A, Caccamo F, Calogero A, Gulizia S, Pellegrino MB, Macchi M, D'Agata R (1986) Enhancing detection of gonococcus in ejaculates of adult males using sperm dilution. Arch Androl 16:19-23.
28. Vicari E, La Vignera S, Castiglione R, Calogero AE (2006) Sperm parameter abnormalities, low seminal fructose and reactive oxygen species overproduction do not discriminate patients with unilateral or bilateral post-infectious inflammatory prostato-vesiculo-epididymitis. J Endocrinol Invest 29:18-25.
29. Wang Y, Liang CL, Wu JQ, Xu C, Qin SX, Gao ES (2006) Do Ureaplasma urealyticum infections in the genital tract affect semen quality? Asian J Androl 8:562-568.
30. Welsh P, Woodward M, Rumley A, Lowe G (2008) Associations of plasma pro-inflammatory cytokines, fibrinogen, viscosity and C-reactive protein with cardiovascular risk factors and social deprivation: the fourth Glasgow MONICA study. Br J Haematol 141:852-861.
31. World Health Organization (1993) WHO manual for the standardized investigation and diagnosis of the infertile couple. In: Special Programme of Research, Development and Research Training in Human Reproduction. Rowe P, Comhaire F, Hargreave TB, Mellows HJ (eds). Cambridge University Press, Cambridge, pp 39-41.
32. World Health Organization (1999) WHO Laboratory Manual for the Examination of the Human Semen and Sperm-Cervical Mucus Interaction, 4th edn. Cambridge University Press, Cambridge.
33. World Health Organization (2010) WHO Laboratory Manual for the Examination of Human Semen, 5th edn. WHO Library Cataloguing-in-Publication Data, Geneva, Switzerland.