Impaired emotional state, quality of life and cognitive functions in young hypogonadal men

Andrologia

Volumn 46, Issue 10, 2014, Pages 1107-1112

  Lasaite L ^a   Ceponis J ^a   Preiksa R T ^a   Zilaitiene B ^a  

^a LITHUANIAN UNIVERSITY OF HEALTH SCIENCES   (Lithuania)

Author keywords

Cognitive functions; Emotional state; Quality of life; Young hypogonadal men

Indexed keywords

ADULT; ATTENTION; COGNITION; EMOTION; EXECUTIVE FUNCTION; HUMAN; HYPOGONADISM; MALE; NEUROPSYCHOLOGICAL TEST; PSYCHOLOGY; QUALITY OF LIFE; QUESTIONNAIRE; YOUNG ADULT;

ADULT; ATTENTION; COGNITION; EMOTIONS; EXECUTIVE FUNCTION; HUMANS; HYPOGONADISM; MALE; NEUROPSYCHOLOGICAL TESTS; QUALITY OF LIFE; QUESTIONNAIRES; YOUNG ADULT;

EID: 84920271328     PISSN: 03034569     EISSN: 14390272     Source Type: Journal    
DOI: 10.1111/and.12199     Document Type: Article

References (34)

1. Amiaz R, Serdman SN (2008) Testosterone and depression in men. Curr Opin Endocrinol Diabetes Obes 15:278-283.
2. Araujo AB, Esche GR, Kupelian V, O'Donnell AB, Travison TG, Williams RE, Clark RV, McKinley JB (2007) Prevalence of symptomatic androgen deficiency in men. J Clin Endocrinol Metab 92:4241-4247.
3. Aydogan U, Aydogan A, Akbulut H, Sonmez A, Yuksel S, Basaran Y, Uzun O, Bolu E, Saglam K (2012) Increased frequency of anxiety, depression, quality of life and sexual life in young hypogonadotropic hypogonadal males and impacts of testosterone replacement therapy on these conditions. Endocr J 59:1099-1105.
4. Barrett-Connor E, Goodman-Gruen D, Patay B (1999) Endogenous sex hormones and cognitive function in older men. J Clin Endocrinol Metab 84:3681-3685.
5. Bhattacharya RK, Khera M, Blick G, Kushner H, Nguyen D, McMiner M (2011) Effects of 12 months of testosterone replacement therapy on metabolic syndrome components in hypogonadal men: data from the Testim Registry in the US (TriUS). BMC Endocr Disord 11:18-28.
6. Blute M, Hakimian P, Kashanian J, Shteynshluyger A, Lee M, Shabsigh R (2009) Erectile dysfunction and testosterone deficiency. Front Horm Res 37:108-122.
7. Falter CM, Arroyo M, Davis GI (2006) Testosterone: activation or organisation of spatial cognition? Biol Psychol 73:132-140.
8. 2) as a measure of fatness. Int J Obes 9:147-153.
9. Grinspoon S, Corcoran C, Stanley T, Baaj A, Basgoz N, Klibanski A (2000) Effects of hypogonadism and testosterone administration on depression indices in HIV-infected men. J Clin Endocrinol Metab 85:60-65.
10. Janowsky JS (2006) Thinking with our gonads: testosterone and cognition. Trends Cogn Sci 10920:77-82.
11. Kortte KB, Horner MD, Windham WK (2002) The trail making test, part B: cognitive flexibility or ability to maintain set? Appl Neuropsychol 9:106-109.
12. LeBlanc ES, Wang PY, Janowsky JS, Neiss MB, Fink HA, Yaffe K, Marshall LM, Lapidus JA, Stefanick ML, Orwoll ES; Osteoporotic Fractures in Men (MrOS) Research Group (2010) Association between sex steroids and cognition in elderly men. Clin Endocrinol 72:393-403.
13. Leranth C, Petnehazy O, MacLusky NJ (2003) Gonadal hormones affect spine synaptic density in the CAI hippocampal subfield of male rats. J Neurosci 23:1588-1592.
14. Leranth C, Prange-Kiel J, Frick KM, Horvath TL (2004) Low CAI spine synapse density is further reduced by castration in male non-human primates. Cereb Cortex 14:503-510.
15. Lessov-Schlaggar CN, Reed T, Swan GE, Krasnow RE, DeCarli C, Marcus R, Holloway L, Wolf PA, Carmelli D (2005) Association of sex steroid hormones with brain morphology and cognition in healthy elderly men. Neurology 65:1591-1596.
16. Lim D, Flicker L, Dharamarajan A, Martins RN (2003) Can testosterone replacement decrease the memory problem of old age? Med Hypotheses 60:893-896.
17. Martin DM, Wittert G, Burns NR, Haren MT, Sugarman R (2007) Testosterone and cognitive functioning in ageing men; data from the Florey Adelaide Male Study (FAMAS). Maturitas 57:182-194.
18. McNair O, Lorr M, Droppleman LF (eds) (1992) EDITS Manual for the Profile of Mood States. Educational and Institutional Testing Service, San Diego, CA.
19. Mehta PH, Josephs RA (2011) Social endocrinology: hormones and social motivation. In: The handbook of social motivation. Dumning D (ed). Psychology Press, New York, pp 171-189.
20. Moffat SD, Zonderman AB, Metter EJ, Blackman MR, Harman SM, Resnick SM (2002) Longitudinal assessment of serum free testosterone concentration predicts memory performance and cognitive status in elderly men. J Clin Endocrinol Metab 87:5001-5007.
21. Moncada I (2006) Testosterone and men's quality of life. Aging Male 9:189-193.
22. Mulligan T, Frick MF, Zuraw OC, Stemhagen A, McWhirter C (2006) Prevalence of hypogonadism in males aged at least 45 years: the HIM study. Int J Clin Pract 60:762-769.
23. O'Connor DB, Archer J, Hair WM, Wu FC (2001) Activational effects of testosterone on cognitive function in men. Neuropsychologia 39:1385-1394.
24. Ramsden M, Nyborg AC, Murphy MP, Chang L, Stanczyk FZ, Golde TE, Pike CJ (2003) Androgens modulate beta-amyloid levels in male rat brain. J Neurochem 87:1052-1055.
25. Reitan RM, Tarshes EL (1959) Differential effects of lateralized brain lesions on the trail making test. J Nerv Ment Dis 129:257-262.
26. Salminen EK, Portin RI, Koskinen A, Helenius H, Nurmi M (2004) Association between serum testosterone fall and cognitive function in prostate cancer patients. Clin Cancer Res 10:7575-7582.
27. Schmidt PJ, Berlin KL, Danaccan MA (2011) The effects of pharmacologically induced hypogonadism on mood in healthy men. Arch Gen Psychiatry 51:997-1003.
28. Schultheiss OC, Wirth MM, Torges CM, Pang JS, Villacorta MA, Welsh KM (2005) Effects of implicit power motivation on men's and women's implicit learning and testosterone changes after social victory or defeat. J Pers Soc Psychol 88:174-188.
29. Wang C, Cunningham G, Dobs A, Iranmanesh A, Matsumoto AM, Snyder PJ, Weber T, Berman N, Hull L, Swerdloff RS (2004) Long-term testosterone gel (AndroGel) treatment maintains beneficial effects on sexual function and mood, lean and fat mass, and bone mineral density in hypogonadal men. J Clin Endocrinol Metab 89:2085-2098.
30. Wechsler D (1981) WAIS-R Manual. Psychological Corporation, New York.
31. WHO (1995) Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee. World Health Organization, Geneva (WHO Technical Report Series, No. 854) 1-36.
32. WHO (1996) WHOQOL-BREF: introduction, administration, scoring and generic version of the assessment. World Health, Organization. Field Trail Version.
33. Yassin AA, Saad F, Gooren LJ (2008) Metabolic syndrome, testosterone deficiency and erectile dysfunction never come alone. Andrologia 40:259-264.
34. Žilaitiene B, Lašaite L, Žilaityte V, Matulevičius V (2006) Testosterone levels and cognitive functioning in 209 young lithuanian men. Baltic Endocrinol 2:53-57.