Renin knockout rat: Control of adrenal aldosterone and corticosterone synthesis in vitro and adrenal gene expression

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 308, Issue 1, 2015, Pages R73-R77

  Raff, Hershel ^a,b   Gehrand, Ashley ^a   Bruder, Eric D ^a   Hoffman, Matthew J ^b   Engeland, William C ^c   Moreno, Carol ^b  

^a ST LUKE S MEDICAL CENTER   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

Adrenal cortex; Aldosterone; Corticosterone; Knockout rat; Renin

Indexed keywords

ALDOSTERONE; ALDOSTERONE SYNTHASE; CORTICOSTERONE; MESSENGER RNA; POTASSIUM; RENIN; SODIUM; ANGIOTENSIN II; BUCLADESINE;

ALDOSTERONE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GLOMERULOSA CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KNOCKOUT RAT; LIMIT OF DETECTION; NONHUMAN; PLASMA RENIN ACTIVITY; POTASSIUM BLOOD LEVEL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SODIUM BLOOD LEVEL; STEROIDOGENESIS; STIMULATION; WILD TYPE RAT; ZONA FASCICULATA; ADRENAL GLAND; ANIMAL; BIOSYNTHESIS; BLOOD; DAHL RAT; DEFICIENCY; DOSE RESPONSE; DRUG EFFECTS; FEEDBACK SYSTEM; GENE INACTIVATION; GENETICS; GENOTYPE; METABOLISM; PHENOTYPE; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TRANSGENIC RAT; ZONA GLOMERULOSA; ZONA RETICULARIS;

ADRENAL GLANDS; ALDOSTERONE; ANGIOTENSIN II; ANIMALS; BUCLADESINE; CORTICOSTERONE; CYTOCHROME P-450 CYP11B2; DOSE-RESPONSE RELATIONSHIP, DRUG; FEEDBACK, PHYSIOLOGICAL; FEMALE; GENE KNOCKOUT TECHNIQUES; GENOTYPE; PHENOTYPE; RATS, INBRED DAHL; RATS, TRANSGENIC; RENIN; RENIN-ANGIOTENSIN SYSTEM; RNA, MESSENGER; ZONA FASCICULATA; ZONA GLOMERULOSA; ZONA RETICULARIS;

EID: 84920268349     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00440.2014     Document Type: Article

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