Long lasting perfume e A review of synthetic musks in WWTPs

Journal of Environmental Management

Volumn 149, Issue 1, 2015, Pages 168-192

  Homem, Vera ^a   Silva, José Avelino ^a   Ratola, Nuno ^b   Santos, Lúcia ^a   Alves, Arminda ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF MURCIA   (Spain)

Author keywords

Removal efficiency; Synthetic musks; Wastewater treatment plants

Indexed keywords

ACTIVATED SLUDGE PROCESS; EFFLUENTS; REMOVAL; WASTEWATER TREATMENT;

CONTINUOUS INPUT; EMERGING POLLUTANTS; HOUSEHOLD PRODUCTS; LONG LASTING; LOW CONCENTRATIONS; PERSONAL CARE PRODUCTS; REMOVAL EFFICIENCIES; SCIENTIFIC COMMUNITY; SYNTHETIC MUSKS; WASTE WATER TREATMENT PLANTS;

EFFICIENCY;

MUSK; PERFUME; ACETYL METHYL TETRAMETHYL TETRALIN; BENZOPYRAN DERIVATIVE; GALAXOLIDE; SEWAGE; TETRALIN DERIVATIVE; WATER POLLUTANT;

ACTIVATED SLUDGE; COST-BENEFIT ANALYSIS; EFFLUENT; PERSISTENCE; POLLUTANT REMOVAL; SEWAGE TREATMENT;

ACTIVATED SLUDGE; BIODEGRADATION; HUMAN; HYDROPHILICITY; HYDROXYLATION; MICROBIAL DEGRADATION; PHOTODEGRADATION; REVIEW; SEWAGE TREATMENT PLANT; SYSTEMATIC REVIEW; WASTE WATER TREATMENT PLANT; ANALYSIS; CHEMISTRY; ENVIRONMENTAL MONITORING; PROCEDURES; SEWAGE; STATISTICS AND NUMERICAL DATA; WATER MANAGEMENT; WATER POLLUTANT;

BENZOPYRANS; ENVIRONMENTAL MONITORING; PERFUME; SEWAGE; TETRAHYDRONAPHTHALENES; WASTE DISPOSAL, FLUID; WATER POLLUTANTS, CHEMICAL; WATER PURIFICATION;

EID: 84920267914     PISSN: 03014797     EISSN: 10958630     Source Type: Journal    
DOI: 10.1016/j.jenvman.2014.10.008     Document Type: Review

References (99)

1. Amy, G., Brdjanovic, D., Comeau, Y., Ekama, G.A., Garcia, J.H.O., Gerba, C.P., Henze, M., Hooijmans, C.M., Judd, S., Kim, B.-G., Lier, K.B.V., Mahmoud, N., Martins, A.M., Morgenroth, E.F., Olsson, G., Rosso, D., Stenstrom, M.K., Takacs, I., Loosdrecht, M.C.M.V., Wentzel, M.C., Zeeman, G., 2008. Biological Wastewater Treatment: Principles, Modelling and Design. IWA Publishing, UK.
2. Arbulu, M., Sampedro, M.C., Unceta, N., Gomez-Caballero, A., Goicolea, M.A., Barrio, R.J., 2011. A retention time locked gas chromatography-mass spectrometry method based on stir-bar sorptive extraction and thermal desorption for automated determination of synthetic musk fragrances in natural and wastewaters. J. Chromatogr. A 1218 (20), 3048-3055.
3. Artola-Garicano, E., Borkent, I., Hermens, J.L.M., Vaes, W.H.J., 2003a. Removal of two polycyclic musks in sewage treatment Plants freely dissolved and total concentrations. Environ. Sci. Technol. 37, 3111-3116.
4. Artola-Garicano, E., Hermens, J.L.M., Vaes, W.H.J., 2003b. Evaluation of Simple Treat 3.0 for two hydrophobic and slowly biodegradable chemicals: polycyclic musks HHCB and AHTN. Water Res. 37 (18), 4377-4384.
5. Berset, J.D., Kupper, T., Etter, R., Tarradellas, J., 2004. Considerations about the enantioselective transformation of polycyclic musks in wastewater, treated wastewater and sewage sludge and analysis of their fate in a sequencing batch reactor plant. Chemosphere 57 (8), 987-996.
6. Bester, K., 2004. Retention characteristics and balance assessment for two polycyclic musk fragrances (HHCB and AHTN) in a typical German sewage treatment plant. Chemosphere 57 (8), 863-870.
7. Bester, K., 2005. Polycyclic musks in the Ruhr catchment areadtransport, discharges of waste water, and transformations of HHCB, AHTN and HHCB-lactone. J. Environ. Monit. 7, 43-51.
8. Bu, Q., Wang, B., Huang, J., Deng, S., Yu, G., 2013. Pharmaceuticals and personal care products in the aquatic environment in China: a review. J. Hazard Mater. 262, 189-211.
9. Buerge, I.J., Buser, H.-R., Müller, M.D., Poiger, T., 2003. Behavior of the polycyclic musks HHCB and AHTN in lakes, two potential anthropogenic markers for domestic wastewater in surface waters. Environ. Sci. Technol. 37, 5636-5644.
10. Cabeza, Y., Candela, L., Ronen, D., Teijon, G., 2012. Monitoring the occurrence of emerging contaminants in treated wastewater and groundwater between 2008 and 2010. The Baix Llobregat (Barcelona, Spain). J. HazardMater. 239-240, 32-39.
11. Carballa, M., Omil, F., Lema, J.M., Llompart, M., Garcia-Jares, C., Rodriguez, I., Gomez, M., Ternes, T., 2004. Behavior of pharmaceuticals, cosmetics and hormones in a sewage treatment plant. Water Res. 38 (12), 2918-2926.
12. Cavalheiro, J., Prieto, A., Monperrus, M., Etxebarria, N., Zuloaga, O., 2013. Determination of polycyclic and nitro musks in environmental water samples by means of microextraction by packed sorbents coupled to large volume injection-gas chromatography-mass spectrometry analysis. Anal. Chim. Acta 773, 68-75.
13. Chase, D.A., Karnjanapiboonwong, A., Fang, Y., Cobb, G.P., Morse, A.N., Anderson, T.A., 2012. Occurrence of synthetic musk fragrances in effluent and non-effluent impacted environments. Sci. Total Environ. 416, 253-260.
14. Chen, D., Zeng, X., Sheng, Y., Bi, X., Gui, H., Sheng, G., Fu, J., 2007. The concentrations and distribution of polycyclic musks in a typical cosmetic plant. Chemosphere 66 (2), 252-258.
15. Chen, X., Pauly, U., Renfus, S., Bester, K., 2009. Personal care compounds in a reed bed sludge treatment system. Chemosphere 76, 1094-1101.
16. Chou, Y.-J., Dietrich, D.R., 1999. Interactions of nitromusk parent compounds and their amino-metabolites with the estrogen receptors of rainbow trout (Oncorhynchus mykiss) and the South African clawed frog (Xenopus laevis). Toxicol. Lett. 111, 27-36.
17. Clara, M., Strenn, B., Gans, O., Martinez, E., Kreuzinger, N., Kroiss, H., 2005. Removal of selected pharmaceuticals, fragrances and endocrine disrupting compounds in a membrane bioreactor and conventional wastewater treatment plants. Water Res. 39 (19), 4797-4807.
18. Commision, O.S.P.A.R., 2000. OSPAR Background Document on Musk Xylene and Other Musks. OSPAR Commission.
19. Correia, P., Cruz, A., Santos, L., Alves, A., 2013. Human dermal exposure to galaxolide from personal care products. Int. J. Cosmet. Sci. 35 (3), 299-309.
20. Dsikowitzky, L., Schwarzbauer, J., Littke, R., 2002. Distribution of polycyclic musks in water and particulate matter of the Lippe River (Germany). Org. Geochem 33, 1747-1758.
21. Duedahl-Olesen, L., Cederberg, T., Pedersen, K.H., Hojgard, A., 2005. Synthetic musk fragrances in trout from Danish fish farms and human milk. Chemosphere 61 (3), 422-431.
22. European Commission, 2011. Commision regulation (EU) No. 143/2011 of 17 February 2011 amending Annex XIV to regulation (EC) No 1907/2006 of the european parliament and of the Council on the registration, evaluation, authorisation and restriction of chemicals ('REACH'). Off. J. Eur. Union 2-6. L44.
23. European Parliament, 2009. Regulation (EC) No. 1223/2009 of the european parliament and of the Council of 30 November 2009 on cosmetic products. Off. J. Eur. Union 59-209. L 342.
24. Fromme, H., Otto, T., Pilz, K., 2001. Polycyclic musk fragrances in different environmental compartments in Berlin (Germany). Water Res. 35, 121-128.
25. García-Jares, C., Llompart, M., Polo, M., Salgado, C., Macías, S., Cela, R., 2002. Optimisation of a solid-phase microextraction method for synthetic musk compounds in water. J. Chromatogr. A 963, 277-285.
26. Gatermann, R., Hühnerfuss, H., Rimkus, G., Attar, A., Kettrup, A., 1998. Occurrence of musk xylene and musk ketone metabolites in the aquatic environment. Chemosphere 36, 2535-2547.
27. Gatermann, R., Biselli, S., Huhnerfuss, H., Rimkus, G.G., Hecker, M., Karbe, L., 2002. Synthetic musks in the environment. Part 1: species-dependent bioaccumulation of polycyclic and nitro musk fragrances in freshwater fish and mussels. Arch. Environ. Contam. Toxicol. 42 (4), 437-446.
28. Godayol, A., Besalú, E., Anticó, E., Sanchez, J.M., 2015. Monitoring of sixteen fragrance allergens and two polycyclic musks in wastewater treatment plants by solid phase microextraction coupled to gas chromatography. Chemosphere 119, 363-370.
29. Gómez, M.J., Gomez-Ramos, M.M., Aguera, A., Mezcua, M., Herrera, S., Fernandez- Alba, A.R., 2009. A new gas chromatography/mass spectrometry method for the simultaneous analysis of target and non-target organic contaminants in waters. J. Chromatogr. A 1216 (18), 4071-4082.
30. Guo, R., Lee, I.S., Kim, U.J., Oh, J.E., 2010. Occurrence of synthetic musks in Korean sewage sludges. Sci. Total Environ. 408 (7), 1634-1639.
31. Herren, D., Berset, J.D., 2000. Nitro musks, nitro musk amino metabolites and polycyclic musks in sewage sludges: quantitative determination by HRGC-iontrap- MS/MS and mass spectral characterization of the amino metabolites. Chemosphere 40, 565-574.
32. Homem, V., Silva, J.A., Cunha, C., Alves, A., Santos, L., 2013. New analytical method for the determination of musks in personal care products by Quick, Easy, Cheap, Effective, Rugged, and safe extraction followed by GC-MS. J. Sep. Sci. 36 (13), 2176-2184.
33. Horii, Y., Reiner, J.L., Loganathan, B.G., Senthil Kumar, K., Sajwan, K., Kannan, K., 2007. Occurrence and fate of polycyclic musks in wastewater treatment plants in Kentucky and Georgia. U. S. A. Chem. 68 (11), 2011-2020.
34. Hu, Z., Shi, Y., Zhang, S., Niu, H., Cai, Y., 2011. Assessment of synthetic musk fragrances in seven wastewater treatment plants of Beijing, China. Bull. Environ. Contam. Toxicol. 86 (3), 302-306.
35. Jones-Lepp, T.L., Stevens, R., 2007. Pharmaceuticals and personal care products in biosolids/sewage sludge: the interface between analytical chemistry and regulation. Anal. Bioanal. Chem. 387 (4), 1173-1183.
36. Klaschka, U., von der Ohe, P.C., Bschorer, A., Krezmer, S., Sengl, M., Letzel, M., 2013. Occurrences and potential risks of 16 fragrances in five German sewage treatment plants and their receiving waters. Environ. Sci. Pollut. Res. Int. 20 (4), 2456-2471.
37. Kupper, T., Plagellat, C., Brandli, R.C., de Alencastro, L.F., Grandjean, D., Tarradellas, J., 2006. Fate and removal of polycyclic musks, UV filters and biocides during wastewater treatment. Water Res. 40 (14), 2603-2612.
38. Lee, I.S., Lee, S.H., Oh, J.E., 2010. Occurrence and fate of synthetic musk compounds in water environment. Water Res. 44 (1), 214-222.
39. Lishman, L., Smyth, S.A., Sarafin, K., Kleywegt, S., Toito, J., Peart, T., Lee, B., Servos, M., Beland, M., Seto, P., 2006. Occurrence and reductions of pharmaceuticals and personal care products and estrogens by municipal wastewater treatment plants in Ontario, Canada. Sci. Total Environ. 367 (2-3), 544-558.
40. Liu, J.L., Wong, M.H., 2013. Pharmaceuticals and personal care products (PPCPs): a review on environmental contamination in China. Environ. Int. 59C, 208-224.
41. Liu, H., Liu, L., Xiong, Y., Yang, X., Luan, T., 2010. Simultaneous determination of UV filters and polycyclic musks in aqueous samples by solid-phase microextraction and gas chromatography-mass spectrometry. J. Chromatogr. A 1217 (43), 6747-6753.
42. Liu, N., Shi, Y., Li, W., Xu, L., Cai, Y., 2014. Concentrations and distribution of synthetic musks and siloxanes in sewage sludge of wastewater treatment plants in China. Sci. Tot. Environ. 476-477, 65-72.
43. López-Nogueroles, M., Chisvert, A., Salvador, A., Carretero, A., 2011. Dispersive liquid-liquid microextraction followed by gas chromatography-mass spectrometry for the determination of nitro musks in surface water and wastewater samples. Talanta 85 (4), 1990-1995.
44. Lv, Y., Yuan, T., Hu, J., Wang, W., 2009. Simultaneous determination of trace polycyclic and Nitro musks in water samples using optimized solid-phase extraction by Gas chromatography and mass spectrometry. Anal. Sci. 25, 1125-1130.
45. Lv, Y., Yuan, T., Hu, J., Wang, W., 2010. Seasonal occurrence and behavior of synthetic musks (SMs) during wastewater treatment process in Shanghai, China. Sci. Total Environ. 408 (19), 4170-4176.
46. Martin, C., Moeder, M., Daniel, X., Krauss, G., Schlosser, D., 2007. Biotransformation of the polycyclic musks HHCB and AHTN and metabolite formation by fungi occurring in freshwater environments. Environ. Sci. Technol. 41 (15), 5395-5402.
47. Matamoros, V., Nguyen, L.X., Arias, C.A., Nielsen, S., Laugen, M.M., Brix, H., 2012. Musk fragrances, DEHP and heavy metals in a 20 years old sludge treatment reed bed system. Water Res. 46 (12), 3889-3896.
48. Moeder, M., Schrader, S., Winkler, U., Rodil, R., 2010. At-line microextraction by packed sorbent-gas chromatography-mass spectrometry for the determination of UV filter and polycyclic musk compounds in water samples. J. Chromatogr. A 1217 (17), 2925-2932.
49. Müller, J., Böhmer, W., Litz, N.T., 2006. Occurrence of polycyclic musks in sewage sludge and their behaviour in soils and plants. Part 1: behaviour of polycyclic musks in sewage sludge of different treatment plants in summer and Winter (5 pp). J. Soil Sediment. 6 (4), 231-235.
50. Musolff, A., Leschik, S., Moder, M., Strauch, G., Reinstorf, F., Schirmer, M., 2009. Temporal and spatial patterns of micropollutants in urban receiving waters. Environ. Pollut. 157 (11), 3069-3077.
51. Nakata, H., Shinohara, R., Nakazawa, Y., Isobe, T., Sudaryanto, A., Subramanian, A., Tanabe, S., Zakaria, M.P., Zheng, G.J., Lam, P.K., Kim, E.Y., Min, B.Y., We, S.U., Viet, P.H., Tana, T.S., Prudente, M., Frank, D., Lauenstein, G., Kannan, K., 2012. Asia-Pacific mussel watch for emerging pollutants: distribution of synthetic musks and benzotriazole UV stabilizers in Asian and US coastal waters. Mar. Pollut. Bull. 64 (10), 2211-2218.
52. Osemwengie, L.I., Gerstenberger, S.L., 2004. Levels of synthetic musk compounds in municipal wastewater for potential estimation of biota exposure in receiving waters. J. Environ. Monit. 6, 533-539.
53. Osemwengie, L.I., Steinberg, S., 2001. On-site solid-phase extraction and laboratory analysis of ultra-trace synthetic musks in municipal sewage effluent using gas chromatographyemass spectrometry in the full-scan mode. J. Chromatogr. A 932, 107-118.
54. Osenbruck, K., Glaser, H.R., Knoller, K., Weise, S.M., Moder, M., Wennrich, R., Schirmer, M., Reinstorf, F., Busch, W., Strauch, G., 2007. Sources and transport of selected organic micropollutants in urban groundwater underlying the city of Halle (Saale), Germany. Water Res. 41 (15), 3259-3270.
55. Paxéus, N., 1996. Organic pollutants in the effluents of large wastewater treatment plants in Sweden. Water Res. 30, 1115-1122.
56. Peck, A., Hornbuckle, K., 2006. Synthetic musk fragrances in urban and rural air of Iowa and the Great Lakes. Atmos. Environ. 40 (32), 6101-6111.
57. Pintado-Herrera, M.G., Gonzalez-Mazo, E., Lara-Martin, P.A., 2013. Environmentally friendly analysis of emerging contaminants by pressurized hot water extraction-stir bar sorptive extraction-derivatization and gas chromatographymass spectrometry. Anal. Bioanal. Chem. 405 (1), 401-411.
58. Polo, M., Garcia-Jares, C., Llompart, M., Cela, R., 2007. Optimization of a sensitive method for the determination of nitro musk fragrances in waters by solid-phase microextraction and gas chromatography with micro electron capture detection using factorial experimental design. Anal. Bioanal. Chem. 388 (8), 1789-1798.
59. Posada-Ureta, O., Olivares, M., Navarro, P., Vallejo, A., Zuloaga, O., Etxebarria, N., 2012. Membrane assisted solvent extraction coupled to large volume injectiongas chromatography-mass spectrometry for trace analysis of synthetic musks in environmental water samples. J. Chromatogr. A 1227, 38-47.
60. Ramírez, N., Marcé, R.M., Borrull, F., 2011. Development of a stir bar sorptive extraction and thermal desorption-gas chromatography-mass spectrometry method for determining synthetic musks in water samples. J. Chromatogr. A 1218 (1), 156-161.
61. Ramírez, N., Borrull, F., Marcé, R.M., 2012. Simultaneous determination of parabens and synthetic musks in water by stir-bar sorptive extraction and thermal desorption-gas chromatography-mass spectrometry. J. Sep. Sci. 35 (4), 580-588.
62. Regueiro, J., Llompart, M., Garcia-Jares, C., Garcia-Monteagudo, J.C., Cela, R., 2008. Ultrasound-assisted emulsification-microextraction of emergent contaminants and pesticides in environmental waters. J. Chromatogr. A 1190 (1-2), 27-38.
63. Reiner, J.L., Kannan, K., 2010. Polycyclic musks in water, sediment, and fishes from the upper Hudson river, New York, USA. Wat Air Soil Pollut. 214 (1-4), 335-342.
64. Reiner, J.L., Berset, J.D., Kannan, K., 2007. Mass flow of polycyclic musks in two wastewater treatment plants. Arch. Environ. Contam. Toxicol. 52 (4), 451-457.
65. Ren, Y., Wei, K., Liu, H., Sui, G., Wang, J., Sun, Y., Zheng, X., 2013. Occurrence and removal of selected polycyclic musks in two sewage treatment plants in Xi'an, China. Front. Environ. Sci. Eng. 7 (2), 166-172.
66. Richardson, B.J., Lam, P.K., Martin, M., 2005. Emerging chemicals of concern: pharmaceuticals and personal care products (PPCPs) in Asia, with particular reference to Southern China. Mar. Pollut. Bull. 50 (9), 913-920.
67. Ricking, M., Schwarzbauer, J., Hellou, J., Svenson, A., Zitko, V., 2003. Polycyclic aromatic musk compounds in sewage treatment plant effluents of Canada and Swedeneefirst results. Mar. Pollut. Bull. 46 (4), 410-417.
68. Rosal, R., Rodriguez, A., Perdigon-Melon, J.A., Petre, A., Garcia-Calvo, E., Gomez, M.J., Aguera, A., Fernandez-Alba, A.R., 2010. Occurrence of emerging pollutants in urban wastewater and their removal through biological treatment followed by ozonation. Water Res. 44 (2), 578-588.
69. Salgado, R., Marques, R., Noronha, J.P., Mexia, J.T., Carvalho, G., Oehmen, A., Reis, M.A., 2011. Assessing the diurnal variability of pharmaceutical and personal care products in a full-scale activated sludge plant. Environ. Pollut. 159 (10), 2359-2367.
70. Sanin, F., Clarkson, W., Vesilind, P., 2011. Sludge Engineering e the Treatment and Disposal of Wastewater Sludges. DEStech Publications Inc.
71. Shek, W.M., Murphy, M.B., Lam, J.C., Lam, P.K., 2008. Synthetic polycyclic musks in Hong Kong sewage sludge. Chemosphere 71 (7), 1241-1250.
72. Silva, A.R., Nogueira, J.M., 2010. Stir-bar-sorptive extraction and liquid desorption combined with large-volume injection gas chromatography-mass spectrometry for ultra-trace analysis of musk compounds in environmental water matrices. Anal. Bioanal. Chem. 396 (5), 1853-1862.
73. Simonich, S.L., 2005. Fragrance materials in wastewater treatment. In: Rimkus, G. (Ed.), The Handbook of Environmental Chemistry, Part O, vol. 5. Springer, pp. 79-118.
74. Simonich, S.L., Begley, W.M., Debaere, G., Eckhoff, W.S., 2000. Trace analysis of fragrance materials in wastewater and treated wastewater. Environ. Sci. Technol. 34, 959.
75. Simonich, S., Federle, T.W., Eckhoff, W.S., Rottiers, A., Webb, S., Sabaliunas, D., De Wolf, W., 2002. Removal of fragrance materials during U.S. and european wastewater treatment. Environ. Sci. Technol. 36, 2839-2847.
76. Smyth, S.A., Lishman, L., Alaee, M., Kleywegt, S., Svoboda, L., Yang, J.J., Lee, H.B., Seto, P., 2007. Sample storage and extraction efficiencies in determination of polycyclic and nitro musks in sewage sludge. Chemosphere 67 (2), 267-275.
77. Stevens, J.L., Northcott, G.L., Stern, G.A., Tomy, G.T., Jones, K.C., 2003. PAHs, PCBs, PCNs, organochlorine pesticides, synthetic musks, and polychlorinated n-alkanes in UK sewage sludge: survey results and implications. Environ. Sci. Technol. 37, 462-467.
78. Sumner, N.R., Guitart, C., Fuentes, G., Readman, J.W., 2010. Inputs and distributions of synthetic musk fragrances in an estuarine and coastal environment; a case study. Environ. Pollut. 158 (1), 215-222.
79. Sun, P., Casteel, K., Dai, H., Wehmeyer, K.R., Kiel, B., Federle, T., 2014. Distributions of polycyclic musk frgrance in wastewater treatment plant (WWTP) effluents and sludges in the United States. Sci. Total Environ. 493, 1073-1078.
80. SWECO Environment, 2010. Screening of Musk Substances and Metabolites. Swedish Environmental Protection Agency.
81. Tchobanoglous, G., Burton, F.L., Stensel, H.D., 2003. Wastewater Engineering: Treatment and Reuse. McGraw-Hill Science Engineering.
82. Ternes, T.A., Stüber, J., Herrmann, N., McDowell, D., Ried, A., Kampmann, M., Teiser, B., 2003. Ozonation: a tool for removal of pharmaceuticals, contrast media and musk fragrances from wastewater? Water Res. 37 (8), 1976-1982.
83. Ternes, T.A., Bonerz, M., Herrmann, N., Löffler, D., Keller, E., Lacida, B.B., Alder, A.C., 2005. Determination of pharmaceuticals, iodinated contrast media and musk fragrances in sludge by LC tandem MS and GC/MS. J. Chromatogr. A 1067 (1-2), 213-223.
84. Toivanen, N., Toimela, T., Tähti, H., 2008. Effect of polycyclic musks on the aromatase activity in JEG-3 chorion carcinoma cells. Toxicol. Lett. 180. S118eS118.
85. Upadhyay, N., Sun, Q., Allen, J.O., Westerhoff, P., Herckes, P., 2011. Synthetic musk emissions from wastewater aeration basins. Water Res. 45 (3), 1071-1078.
86. Vallecillos, L., Pocurull, E., Borrull, F., 2012a. Fully automated determination of macrocyclic musk fragrances in wastewater by microextraction by packed sorbents and large volume injection gas chromatography-mass spectrometry. J. Chromatogr. A 1264, 87-94.
87. Vallecillos, L., Pocurull, E., Borrull, F., 2012b. Fully automated ionic liquid-based headspace single drop microextraction coupled to GC-MS/MS to determine musk fragrances in environmental water samples. Talanta 99, 824-832.
88. Vallecillos, L., Pocurull, E., Borrull, F., 2013. A simple and automated method to determine macrocyclic musk fragrances in sewage sludge samples by headspace solid-phase microextraction and gas chromatography-mass spectrometry. J. Chromatogr. A 1314, 38-43.
89. Vallecillos, L., Pocurull, E., Borrull, F., 2014. On-line coupling of solid-phase extraction to gas chromatography-mass spectrometry to determine musk fragrances in wastewater. J. Chromatogr. A 1364, 1-11.
90. Wang, Y.C., Ding, W.H., 2009. Determination of synthetic polycyclic musks in water by microwave-assisted headspace solid-phase microextraction and gas chromatography-mass spectrometry. J. Chromatogr. A 1216 (40), 6858-6863.
91. Weiner, R.E., Matthews, R.A., 2003. Environmental Engineering. Butterworth-Heineman, USA. Wu, S.F., Ding, W.H., 2010. Fast determination of synthetic polycyclic musks in sewage sludge and sediments by microwave-assisted headspace solid-phase microextraction and gas chromatography-mass spectrometry. J. Chromatogr. A 1217 (17), 2776-2781.
92. Yamagishi, T., Miyazaki, T., Horii, S., Akiyama, K., 1983. Synthetic musk residues in biota and water from Tama River and Tokyo Bay (Japan). Arch. Environ. Contam. Toxicol. 12, 83-89.
93. Yamauchi, R., Ishibashi, H., Hirano, M., Mori, T., Kim, J.W., Arizono, K., 2008. Effects of synthetic polycyclic musks on estrogen receptor, vitellogenin, pregnane X receptor, and cytochrome P450 3A gene expression in the livers of male medaka (Oryzias latipes). Aquat. Toxicol. 90 (4), 261-268.
94. Yang, C.Y., Ding, W.H., 2012. Determination of synthetic polycyclic musks in aqueous samples by ultrasound-assisted dispersive liquid-liquid microextraction and gas chromatography-mass spectrometry. Anal. Bioanal. Chem. 402 (4), 1723-1730.
95. Yang, J.J., Metcalfe, C.D., 2006. Fate of synthetic musks in a domestic wastewater treatment plant and in an agricultural field amended with biosolids. Sci. Total Environ. 363 (1-3), 149-165.
96. Zeng, X., Sheng, G., Xiong, Y., Fu, J., 2005. Determination of polycyclic musks in sewage sludge from Guangdong, China using GC-EI-MS. Chemosphere 60 (6), 817-823.
97. Zeng, X., Sheng, G., Gui, H., Chen, D., Shao, W., Fu, J., 2007. Preliminary study on the occurrence and distribution of polycyclic musks in a wastewater treatment plant in Guandong, China. Chemosphere 69 (8), 1305-1311.
98. Zhang, X., Yao, Y., Zeng, X., Qian, G., Guo, Y., Wu, M., Sheng, G., Fu, J., 2008. Synthetic musks in the aquatic environment and personal care products in Shanghai, China. Chemosphere 72 (10), 1553-1558.
99. Zhou, H., Huang, X., Gao, M., Wang, X., Wen, X., 2009. Distribution and elimination of polycyclic musks in three sewage treatment plants of Beijing, China. J. Environ. Sci. 21 (5), 561-567.