The pathway-specific regulatory genes, tei15* and tei16*, are the master switches of teicoplanin production in Actinoplanes teichomyceticus

Applied Microbiology and Biotechnology

Volumn 98, Issue 22, 2014, Pages 9295-9309

  Horbal, Liliya ^a   Kobylyanskyy, Anton ^b   Truman, Andrew W ^d   Zaburranyi, Nestor ^a   Ostash, Bohdan ^a   Luzhetskyy, Andriy ^c   Marinelli, Flavia ^b   Fedorenko, Victor ^a  

^a IVAN FRANKO NATIONAL UNIVERSITY OF LVIV   (Ukraine)

^b UNIVERSITY OF INSUBRIA   (Italy)

^c SAARLAND UNIVERSITY   (Germany)

^d JOHN INNES CENTRE   (United Kingdom)

Author keywords

Actinoplanes; Overproducer; Pathway specific regulators; Strain improvement; Teicoplanin

Indexed keywords

ANTIBIOTICS; BACTERIA; BIOCHEMISTRY; HEALTH RISKS;

ACTINOPLANES; ACTINOPLANES TEICHOMYCETICUS; AMINOGLYCOSIDE RESISTANCE; ANTIBIOTIC-RESISTANT BACTERIA; OVERPRODUCER; STRAIN IMPROVEMENT; TEICOPLANIN; TRANSCRIPTIONAL FACTORS;

TRANSCRIPTION;

ANTIINFECTIVE AGENT; BACTERIAL DNA; TEICOPLANIN;

BIOSYNTHESIS; CHEMISTRY; DNA SEQUENCE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; METABOLIC ENGINEERING; METABOLISM; MICROMONOSPORACEAE; MOLECULAR GENETICS; REGULATOR GENE;

ANTI-BACTERIAL AGENTS; DNA, BACTERIAL; GENE EXPRESSION; GENE EXPRESSION REGULATION, BACTERIAL; GENES, REGULATOR; METABOLIC ENGINEERING; MICROMONOSPORACEAE; MOLECULAR SEQUENCE DATA; SEQUENCE ANALYSIS, DNA; TEICOPLANIN;

EID: 84920250171     PISSN: 01757598     EISSN: 14320614     Source Type: Journal    
DOI: 10.1007/s00253-014-5969-z     Document Type: Article

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