The vancomycin resistance VanRS two-component signal transduction system of Streptomyces coelicolor

Molecular Microbiology

Volumn 59, Issue 3, 2006, Pages 923-935

  Hutchings, Matthew I ^a,b   Hong, Hee Jeon ^a   Buttner, Mark J ^a  

^a JOHN INNES CENTRE   (United Kingdom)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

A47934; BACITRACIN; BACTERIAL PROTEIN; GENE PRODUCT; GLYCOPEPTIDE; MOENOMYCIN A; PHOSPHATASE; PHOSPHATE; PHOSPHOTRANSFERASE; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEIN VANR; PROTEIN VANS; RAMOPLANIN; UNCLASSIFIED DRUG; VANCOMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BIOSYNTHESIS; CELL WALL; CONTROLLED STUDY; ENZYME ACTIVITY; GENE CONSTRUCT; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE INDUCTION; GENE MUTATION; NONHUMAN; NULL ALLELE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; STREPTOMYCES; STREPTOMYCES COELICOLOR; STREPTOMYCES TOYOCAENSIS; WILD TYPE;

ALLELES; AMINO ACID SEQUENCE; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORIC ACID ESTERS; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN KINASES; SEQUENCE DELETION; SIGNAL TRANSDUCTION; STREPTOMYCES COELICOLOR; SUPPRESSION, GENETIC; TRANSCRIPTION FACTORS; VANCOMYCIN; VANCOMYCIN RESISTANCE;

BACTERIA (MICROORGANISMS); STREPTOMYCES; STREPTOMYCES COELICOLOR; STREPTOMYCES TOYOCAENSIS;

EID: 33645050677     PISSN: 0950382X     EISSN: 13652958     Source Type: Journal    
DOI: 10.1111/j.1365-2958.2005.04953.x     Document Type: Article

References (36)

1. Allen NE. Hobbs JN. 1995 Induction of vancomycin resistance in Enterococcus faecium by non-glycopeptide antibiotics FEMS Microbiol Lett 132 107 114
2. Arthur M. Depardieu F. Gerbaud G. Galimand M. Leclercq R. Courvalin P. 1997 The VanS sensor negatively controls VanR-mediated transcriptional activation of glycopeptide resistance genes of Tn1546 and related elements in the absence of induction J Bacteriol 179 97 106
3. Baptista M. Depardieu F. Courvalin P. Arthur M. 1996 Specificity of induction of glycopeptide resistance genes in Enterococcus faecalis Antimicrob Agents Chemother 40 2291 2295
4. Baptista M. Rodrigues P. Depardieu F. Courvalin P. Arthur M. 1999 Single-cell analysis of glycopeptide resistance gene expression in teicoplanin-resistant mutants of a VanB-type Enterococcus faecalis Mol Microbiol 32 17 28
5. Barna JCJ. Williams DH. 1984 The structure and mode of action of glycopeptide antibiotics of the vancomycin group Annu Rev Microbiol 38 339 357
6. Bouché S. Klauck E. Fischer D. Lucassen M. Jung K. Hengge-Aronis R. 1998 Regulation of RssB-dependent proteolysis in Escherichia coli: a role for acetyl phosphate in a response regulator-controlled process Mol Microbiol 27 787 795
7. Bugg TDH. Wright GD. Dutka-Malen S. Arthur M. Courvalin P. Walsh CT. 1991 Molecular basis for vancomycin resistance in Enterococcus faecium BM4147. Biosynthesis of a depsipeptide peptidoglycan precursor by vancomycin resistance proteins VanH and VanA Biochemistry 30 10408 10415
8. Chang S. Sievert DM. Hageman JC. Boulton ML. Tenover FC. Downes FP. et al. 2003 Infection with vancomycin-resistant Staphylococcus aureus containing the vanA resistance gene N Engl J Med 348 1342 1347
9. Datsenko KA. Wanner BL. 2000 One step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products Proc Natl Acad Sci USA 97 6640 6645
10. B G2 ATP-binding motif, leads to constitutive glycopeptide resistance in VanB-type Enterococcus faecium Mol Microbiol 50 1069 1083
11. Gregory MA. Till R. Smith MCM. 2003 Integration site for Streptomyces phage φBT1 and development of site-specific integrating vectors J Bacteriol 185 5320 5323
12. Grissom-Arnold J. Alborn WE. Nicas TI. Jaskunas SR. 1997 Induction of VanA vancomycin resistance genes in Enterococcus faecalis: use of a promoter fusion to evaluate glycopeptide and nonglycopeptide induction signals Microb Drug Resist 3 53 64
13. Gust B. Challis GL. Fowler K. Kieser T. Chater KF. 2003 PCR-targeted Streptomyces gene replacement identifies a protein domain needed for biosynthesis of the sesquiterpene soil odor geosmin Proc Natl Acad Sci USA 18 1541 1546
14. Hakenbeck R. Stock JB. 1996 Analysis of two-component signal transduction system involved in transcriptional regulation Methods Enzymol 273 281 300
15. Haldimann A. Fisher SL. Daniels LL. Walsh CT. Wanner BL. 1997 Transcriptional regulation of the Enterococcus faecium BM4147 vancomycin resistance gene cluster by the VanS-VanR two-component regulatory system in Escherichia coli K-12 J Bacteriol 179 5903 5913
16. Handwerger S. Kolokathis A. 1990 Induction of vancomycin resistance in Enterococcus faecium by inhibition of transglycosylation FEMS Microbiol Lett 58 167 170
17. Healy VL. Lessard IA. Roper DI. Knox JR. Walsh CT. 2000 Vancomycin resistance in enterococci: reprogramming of the d -Ala- d -Ala ligases in bacterial peptidoglycan biosynthesis Chem Biol 7 R109 R119
18. Hong H-J. Paget MSB. Buttner MJ. 2002 A signal transduction system in Streptomyces coelicolor that activates the expression of a putative cell wall glycan operon in response to vancomycin and other cell wall-specific antibiotics Mol Microbiol 44 1199 1211
19. Hong H-J. Hutchings MI. Neu JM. Wright GD. Paget MSB. Buttner MJ. 2004 Characterisation of an inducible vancomycin resistance system in Streptomyces coelicolor reveals a novel gene (vanK) required for drug resistance Mol Microbiol 52 1107 1121
20. Hong HJ. Hutchings MI. Hill LM. Buttner MJ. 2005 The role of the novel Fem protein VanK in vancomycin resistance in Streptomyces coelicolor J Biol Chem 280 13055 13061
21. Hutchings MI. Hoskisson PA. Chandra G. Buttner MJ. 2004 Sensing and responding to diverse extracellular signals? Analysis of the sensor kinases and response regulators of Streptomyces coelicolor A3(2) Microbiology 150 2795 2806
22. Kieser T. Bibb MJ. Buttner MJ. Chater, and Hopwood DA. 2000 Practical Streptomyces Norwich The John Innes Foundation.
23. Lai MH. Kirsch DR. 1996 Induction signals for vancomycin resistance encoded by the vanA gene cluster in Enterococcus faecium Antimicrob Agents Chemother 40 1645 1648
24. Mani N. Sancheti P. Jiang ZD. McNaney C. DeCenzo M. Knight B. et al. 1998 Screening systems for detecting inhibitors of cell wall transglycosylation in Enterococcus. Cell wall transglycosylation inhibitors in Enterococcus J Antibiot 51 471 479
25. Molle V. Buttner MJ. 2000 Different alleles of the response regulator gene bldM arrest Streptomyces coelicolor development at distinct stages Mol Microbiol 36 1265 1278
26. Neu JM. Wright GD. 2001 Inhibition of sporulation, glycopeptide antibiotic production and resistance in Streptomyces toyocaensis NRRL 15009 by protein kinase inhibitors FEMS Microbiol Lett 199 15 20
27. E, is required for normal cell wall structure in Streptomyces coelicolor A3(2) J Bacteriol 181 204 211
28. Pearson H. 2002 'Superbug' hurdles key drug barrier Nature 418 469 470
29. Pootoolal J. Neu J. Wright GD. 2002a Glycopeptide antibiotic resistance Annu Rev Pharmacol Toxicol 42 381 408
30. Pootoolal J. Thomas MG. Marshall CG. Neu, Hubbard BK. Walsh CT. Wright GD. 2002b Assembling the glycopeptide antibiotic scaffold: the biosynthesis of A47934 from Streptomyces toyocaensis Proc Natl Acad Sci USA 99 8962 8967
31. Pruss BM. Wolfe AJ. 1994 Regulation of acetyl phosphate synthesis and degradation, and the control of flagellar expression in Escherichia coli Mol Microbiol 12 973 984
32. Tenover FC. Weigel LM. Appelbaum PC. McDougal LK. Chaitram J. McAllister S. et al. 2004 Vancomycin-resistant Staphylococcus aureus isolate from a patient in Pennsylvania Antimicrob Agents Chemother 48 275 280
33. Ulijasz AT. Grenader A. Weisblum B. 1996 A vancomycin-inducible lacZ reporter system in Bacillus subtilis: induction by antibiotics that inhibit cell wall synthesis and by lysozyme J Bacteriol 178 6305 6309
34. Walsh CT. Fisher SL. Park IS. Prahalad M. Wu Z. 1996 Bacterial resistance to vancomycin: five genes and one missing hydrogen bond tell the story Chem Biol 3 21 28
35. Weigel LM. Clewell DB. Gill SR. Clark NC. McDougal LK. Flannagan SE. et al. 2003 Genetic analysis of a high-level vancomycin-resistant isolate of Staphylococcus aureus Science 28 1569 1571
36. Williams DH. Williamson MP. Butcher DW. Hammond SJ. 1983 Detailed binding sites of the antibiotics vancomycin and ristocetin A: determination of intermolecular distances in antibiotic/substrate complexes by use of the time-dependent NOE J Am Chem Soc 105 1332 1339