Discovery of the migrasome, an organelle mediating release of cytoplasmic contents during cell migration

Cell Research

Volumn 25, Issue 1, 2015, Pages 24-38

  Ma, Liang ^a   Li, Ying ^a   Peng, Junya ^a   Wu, Danni ^a   Zhao, Xiaoxin ^a   Cui, Yitong ^a   Chen, Lilian ^a   Yan, Xiaojun ^b   Du, Yanan ^b,c   Yu, Li ^a  

^a Peking University   (China)

^b Tsinghua University   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Migracytosis; Migrasome; Migration; Retraction fibers; Vesicle

Indexed keywords

ACTIN;

ANIMAL; CELL LINE; CELL MOTION; CELL ORGANELLE; CYTOPLASM; HUMAN; METABOLISM; MOUSE; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE; ULTRASTRUCTURE;

ACTINS; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CELL LINE, TUMOR; CELL MOVEMENT; CYTOPLASM; HUMANS; MICE; ORGANELLES;

EID: 84920167794     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2014.135     Document Type: Article

References (11)

1. Schneider FH, Smith AD, Winkler H. Secretion from the adrenal medulla: biochemical evidence for exocytosis. Br J Pharmacol Chemother 1967; 31:94-104.
2. Nagasawa J, Douglas WW, Schulz RA. Ultrastructural evidence of secretion by exocytosis and of synaptic-vesicle formation in posterior pituitary glands. Nature 1970; 227:407-409.
3. Trams EG, Lauter CJ, Salem N, Heine U. Exfoliation of membrane ecto-enzymes in the form of micro-vesicles. Biochim Biophys Acta 1981; 645:63-70.
4. Johnstone RM, Adam M, Hammond JR, Orr L, Turbide C. vesicle formation during reticulocyte maturation - association of plasma-membrane activities with released vesicles (exosomes). J Biol Chem 1987; 262:9412-9420.
5. Kowal J, Tkach M, Théry C. Biogenesis and secretion of exosomes. Curr Opin Cell Biol 2014; 29:116-125.
6. Porter KR, Claude A, Fullam EF. A study of tissue culture cells by electron microscopy - methods and preliminary observations. J Exp Med 1945; 81:233-246.
7. Taylor AC, Robbins E. Observations on microextensions from the surface of isolated vertebrate cells. Dev Biol 1963; 6:660-673.
8. Rantala JK, Pouwels J, Pellinen T, et al. SHARPIN is an endogenous inhibitor of beta1-integrin activation. Mol Biol Cell 2011; 22:1315-1324.
9. Eleniste PP, Huang S, Wayakanon K, Largura HW, Bruzzaniti A. Osteoblast differentiation and migration are regulated by dynamin GTPase activity. Int J Biochem Cell Biol 2014; 46:9-18.
10. Duxbury MS, Ashley SW, Whang EE. Inhibition of pancreatic adenocarcinoma cellular invasiveness by blebbistatin: a novel myosin II inhibitor. Biochem Biophys Res Commun 2004; 313:992-997.
11. Kriebel PW, Barr VA, Rericha EC, Zhang GF, Parent CA. Collective cell migration requires vesicular trafficking for chemoattractant delivery at the trailing edge. J Cell Biol 2008; 183:949-961.