Predictive biomarkers for the efficacy of cetuximab combined with cisplatin and capecitabine in advanced gastric or esophagogastric junction adenocarcinoma: a prospective multicenter phase 2 trial

Medical Oncology

Volumn 31, Issue 10, 2014, Pages 1-11

  Zhang, Xiaotian ^a   Xu, Jianming ^b   Liu, Huilong ^c   Yang, Lin ^d   Liang, Jun ^e   Xu, Nong ^f   Bai, Yuxian ^g   Wang, Jiejun ^h   Shen, Lin ^a  

^a PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

^b Beijing 307 Hospital   (China)

^c CHINESE PLA GENERAL HOSPITAL   (China)

^d CANCER HOSPITAL   (China)

^e QINGDAO UNIVERSITY   (China)

^f ZHEJIANG UNIVERSITY   (China)

^g Dept of Nasopharyngeal Carcinoma   (China)

^h SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Advanced gastric or esophagogastric junction adenocarcinoma; Cetuximab; EGFR; Rash; TGF

Indexed keywords

AMPHIREGULIN; BIOLOGICAL MARKER; CAPECITABINE; CETUXIMAB; CISPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIREGULIN; K RAS PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA; VASCULOTROPIN; ANTINEOPLASTIC AGENT; DEOXYCYTIDINE; EGFR PROTEIN, HUMAN; FLUOROURACIL; MONOCLONAL ANTIBODY; TUMOR MARKER;

ABDOMINAL PAIN; ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CHEMOTHERAPY INDUCED ANEMIA; CHEMOTHERAPY INDUCED EMESIS; DESQUAMATION; DRUG EFFICACY; DRUG ERUPTION; ELECTROLYTE DISTURBANCE; ESOPHAGEAL ADENOCARCINOMA; FATIGUE; FEBRILE NEUTROPENIA; FEMALE; GASTRECTOMY; GASTROINTESTINAL HEMORRHAGE; GENE AMPLIFICATION; GENE DOSAGE; HAND FOOT SYNDROME; HUMAN; LIVER ABSCESS; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; MULTIPLE CYCLE TREATMENT; NAUSEA; NEUTROPENIA; OVERALL SURVIVAL; PHASE 2 CLINICAL TRIAL (TOPIC); PROGRESSION FREE SURVIVAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; SINGLE NUCLEOTIDE POLYMORPHISM; STOMACH ADENOCARCINOMA; THROMBOCYTOPENIA; ADENOCARCINOMA; ADOLESCENT; ANALOGS AND DERIVATIVES; CLINICAL TRIAL; DRUG EFFECTS; GENETICS; LOWER ESOPHAGUS SPHINCTER; MIDDLE AGED; PATHOLOGY; PHASE 2 CLINICAL TRIAL; STOMACH NEOPLASMS; TREATMENT OUTCOME; YOUNG ADULT;

ADENOCARCINOMA; ADOLESCENT; ADULT; AGED; ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CISPLATIN; DEOXYCYTIDINE; ESOPHAGOGASTRIC JUNCTION; FEMALE; FLUOROURACIL; GENE DOSAGE; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RECEPTOR, EPIDERMAL GROWTH FACTOR; STOMACH NEOPLASMS; TRANSFORMING GROWTH FACTOR ALPHA; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84919917041     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-014-0226-y     Document Type: Article

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