A prospective feasibility study of respiratory-gated proton beam therapy for liver tumors

Practical Radiation Oncology

Volumn 4, Issue 5, 2014, Pages 316-322

  Hong, Theodore S ^a   DeLaney, Thomas F ^a   Mamon, Harvey J ^a   Willett, Christopher G ^b   Yeap, Beow Y ^a   Niemierko, Andrzej ^a   Wolfgang, John A ^a   Lu, Hsiao Ming ^a   Adams, Judith ^a   Weyman, Elizabeth A ^a   Arellano, Ronald S ^a   Blaszkowsky, Lawrence S ^a   Allen, Jill N ^a   Tanabe, Kenneth K ^a   Ryan, David P ^a   Zhu, Andrew X ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; BILE DUCT CARCINOMA; CANCER RECURRENCE; CANCER SURVIVAL; CLINICAL EVALUATION; COLON HEMORRHAGE; COMPUTED TOMOGRAPHY SCANNER; COMPUTER ASSISTED TOMOGRAPHY; DOSE RESPONSE; FATIGUE; FEMALE; GASTROINTESTINAL HEMORRHAGE; HUMAN; HYPERBILIRUBINEMIA; HYPERPIGMENTATION; LIVER CELL CARCINOMA; LIVER METASTASIS; LIVER TUMOR; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PANCREAS ADENOCARCINOMA; PILOT STUDY; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROSPECTIVE STUDY; PROTON THERAPY; RADIATION DOSE; RADIATION EQUIPMENT; STOMACH PERFORATION; SURVIVAL RATE; THROMBOCYTOPENIA; TREATMENT OUTCOME; TUMOR VOLUME; BILE DUCT NEOPLASMS; BREATHING; CANCER STAGING; CARCINOMA, HEPATOCELLULAR; CHOLANGIOCARCINOMA; FEASIBILITY STUDY; FOLLOW UP; INTRAHEPATIC BILE DUCT; LIVER NEOPLASMS; MIDDLE AGED; MORTALITY; PATHOLOGY; PROGNOSIS; RADIOTHERAPY DOSAGE; SECONDARY; TUMOR RECURRENCE; VERY ELDERLY;

PROTON;

ADULT; AGED; AGED, 80 AND OVER; BILE DUCT NEOPLASMS; BILE DUCTS, INTRAHEPATIC; CARCINOMA, HEPATOCELLULAR; CHOLANGIOCARCINOMA; FEASIBILITY STUDIES; FEMALE; FOLLOW-UP STUDIES; HUMANS; LIVER NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PROGNOSIS; PROSPECTIVE STUDIES; PROTONS; RADIOTHERAPY DOSAGE; RESPIRATION; SURVIVAL RATE;

EID: 84919909051     PISSN: 18798500     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.prro.2013.10.002     Document Type: Article

References (15)

1. Dawson L.A., McGinn C.J., Normolle D., et al. Escalated focal liver radiation and concurrent hepatic artery fluorodeoxyuridine for unresectable intrahepatic malignancies. J Clin Oncol 2000, 18:2210-2218.
2. Lee M.T., Kim J.J., Diniwell R., et al. Phase I study of individualized stereotactic body radiotherapy of liver metastases. J Clin Oncol 2009, 27:1585-1591.
3. Bujold A., Massey C.A., Kim J.J., et al. Sequential phase I and II trials of stereotactic body radiotherapy for locally advanced hepatocellular carcinoma. J Clin Oncol 2013, 31:1631-1639.
4. Wang X., Krishnan S., Zhang X., et al. Proton radiotherapy for liver tumors: Dosimetric advantages over photon plans. Med Dosim 2008, 33:259-267.
5. Lu H.M., Brett R., Sharp G., et al. A respiratory-gated treatment system for proton therapy. Med Phys 2007, 34:3273-3278.
6. Hata M., Tokuuye K., Sugahara S., et al. Proton beam therapy for hepatocellular carcinoma with limited treatment options. Cancer 2006, 107:591-598.
7. Hata M., Tokuuye K., Sugahara S., et al. Proton beam therapy for hepatocellular carcinoma with portal vein tumor thrombus. Cancer 2005, 104:794-801.
8. Hata M., Tokuuye K., Sugahara S., et al. Proton beam therapy for aged patients with hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 2007, 69:805-812.
9. Mizumoto M., Tokuuye K., Sugahara S., et al. Proton beam therapy for hepatocellular carcinoma adjacent to the porta hepatis. Int J Radiat Oncol Biol Phys 2008, 71:462-467.
10. Sugahara S., Oshiro Y., Nakayama H., et al. Proton beam therapy for large hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 2010, 76:460-466.
11. Nakayama H., Sugahara S., Tokita M., et al. Proton beam therapy for hepatocellular carcinoma: The University of Tsukuba experience. Cancer 2009, 115:5499-5506.
12. Fukumitsu N., Sugahara S., Nakayama H., et al. A prospective study of hypofractionated proton beam therapy for patients with hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 2009, 74:831-836.
13. Hashimoto T., Tokuuye K., Fukumitsu N., et al. Repeated proton beam therapy for hepatocellular carcinoma. Int J Radiat Oncol Biol Phys 2006, 65:196-202.
14. Kawashima M., Furuse J., Nishio T., et al. Phase II study of radiotherapy employing proton beam for hepatocellular carcinoma. J Clin Oncol 2005, 23:1839-1846.
15. Yoon SS, Aloia TA, Haynes AB, et al. Surgical placement of biologic mesh spacers to displace bowel away from unresectable liver tumors followed by delivery of dose-intense radiation therapy [published online ahead of print September 3, 2013]. Pract Radiat Oncol. doi:10.1016/j.prro.2013.07.007.