-
1
-
-
76049128595
-
Estimates of cancer incidence and mortality in Europe in 2008
-
Ferlay J, Parkin DM, Steliarova-Foucher E. Estimates of cancer incidence and mortality in Europe in 2008. Eur. J. Cancer 46(4), 765-781 (2010).
-
(2010)
Eur. J. Cancer
, vol.46
, Issue.4
, pp. 765-781
-
-
Ferlay, J.1
Parkin, D.M.2
Steliarova-Foucher, E.3
-
2
-
-
78049485263
-
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008
-
Ferlay J, Shin HR, Bray F, Forman D, Mathers C, Parkin DM. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer 127(12), 2893-2917 (2010).
-
(2010)
Int. J. Cancer
, vol.127
, Issue.12
, pp. 2893-2917
-
-
Ferlay, J.1
Shin, H.R.2
Bray, F.3
Forman, D.4
Mathers, C.5
Parkin, D.M.6
-
3
-
-
0036302615
-
Clinical determinants of survival in patients with 5-fluorouracil-based treatment for metastatic colorectal cancer: Results of a multivariate analysis of 3825 patients
-
Kohne CH, Cunningham D, Di Costanzo F et al. Clinical determinants of survival in patients with 5-fluorouracil-based treatment for metastatic colorectal cancer: Results of a multivariate analysis of 3825 patients. Ann. Oncol. 13(2), 308-317 (2002).
-
(2002)
Ann. Oncol.
, vol.13
, Issue.2
, pp. 308-317
-
-
Kohne, C.H.1
Cunningham, D.2
Di Costanzo, F.3
-
4
-
-
56349165203
-
Predictive factors for response and toxicity in Chemotherapy: Pharmacogenomics
-
Sanoff HK, Mcleod HL. Predictive factors for response and toxicity in Chemotherapy: Pharmacogenomics. Semin. Colon Rectal Surg. 19(4), 226-230 (2008).
-
(2008)
Semin. Colon Rectal Surg.
, vol.19
, Issue.4
, pp. 226-230
-
-
Sanoff, H.K.1
McLeod, H.L.2
-
5
-
-
32944463532
-
Analysis of prognostic factors and applicability of Kohne's prognostic groups in patients with metastatic colorectal cancer treated with first-line irinotecan or oxaliplatin-based Chemotherapy
-
Diaz R, Aparicio J, Girones R et al. Analysis of prognostic factors and applicability of Kohne's prognostic groups in patients with metastatic colorectal cancer treated with first-line irinotecan or oxaliplatin-based Chemotherapy. Clin. Colorectal Cancer 5(3), 197-202 (2005).
-
(2005)
Clin. Colorectal Cancer
, vol.5
, Issue.3
, pp. 197-202
-
-
Diaz, R.1
Aparicio, J.2
Girones, R.3
-
6
-
-
84867122727
-
ESMO consensus guidelines for management of patients with colon and rectal cancer a personalized approach to clinical decision making
-
Schmoll HJ, Van Cutsem E, Stein A et al. ESMO Consensus Guidelines for management of patients with colon and rectal cancer. a personalized approach to clinical decision making. Ann. Oncol. 23(10), 2479-2516 (2012).
-
(2012)
Ann. Oncol.
, vol.23
, Issue.10
, pp. 2479-2516
-
-
Schmoll, H.J.1
Van Cutsem, E.2
Stein, A.3
-
7
-
-
77956625930
-
Molecular markers and biological targeted therapies in metastatic colorectal cancer: Expert opinion and recommendations derived from the 11th esmo/world congress on gastrointestinal cancer barcelona 2009
-
Van Cutsem E, Dicato M, Arber N et al. Molecular markers and biological targeted therapies in metastatic colorectal cancer: Expert opinion and recommendations derived from the 11th ESMO/World Congress on Gastrointestinal Cancer, Barcelona, 2009. Ann. Oncol. 21(Suppl. 6), vi1-vi10 (2010).
-
(2010)
Ann. Oncol.
, vol.21
, pp. vi1-vi10
-
-
Van Cutsem, E.1
Dicato, M.2
Arber, N.3
-
8
-
-
77954346705
-
Advanced colorectal cancer: ESMO Clinical Practice Guidelines for treatment
-
Van Cutsem E, Nordlinger B, Cervantes A. Advanced colorectal cancer: ESMO Clinical Practice Guidelines for treatment. Ann. Oncol. 21(Suppl. 5), v93-v97 (2010).
-
(2010)
Ann. Oncol.
, vol.21
, pp. v93-v97
-
-
Van Cutsem, E.1
Nordlinger, B.2
Cervantes, A.3
-
9
-
-
84865509942
-
Treatment decisions after diagnosis of metastatic colorectal cancer
-
Cartwright TH. Treatment decisions after diagnosis of metastatic colorectal cancer. Clin. Colorectal Cancer 11(3), 155-166 (2012).
-
(2012)
Clin. Colorectal Cancer
, vol.11
, Issue.3
, pp. 155-166
-
-
Cartwright, T.H.1
-
10
-
-
84868104706
-
The oncosurgery approach to managing liver metastases from colorectal cancer: A multidisciplinary international consensus
-
Adam R, De Gramont A, Figueras J et al. The oncosurgery approach to managing liver metastases from colorectal cancer: A multidisciplinary international consensus. Oncologist 17(10), 1225-1239 (2012).
-
(2012)
Oncologist
, vol.17
, Issue.10
, pp. 1225-1239
-
-
Adam, R.1
De Gramont, A.2
Figueras, J.3
-
11
-
-
63849088630
-
Cetuximab and Chemotherapy as initial treatment for metastatic colorectal cancer
-
Van Cutsem E, Kohne CH, Hitre E et al. Cetuximab and Chemotherapy as initial treatment for metastatic colorectal cancer. N. Engl. J. Med. 360(14), 1408-1417 (2009).
-
(2009)
N. Engl. J. Med.
, vol.360
, Issue.14
, pp. 1408-1417
-
-
Van Cutsem, E.1
Kohne, C.H.2
Hitre, E.3
-
12
-
-
79956298812
-
Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: Updated analysis of overall survival according to tumor KRAS and BRAF mutation status
-
Van Cutsem E, Kohne CH, Lang I et al. Cetuximab plus irinotecan, fluorouracil, and leucovorin as first-line treatment for metastatic colorectal cancer: Updated analysis of overall survival according to tumor KRAS and BRAF mutation status. J. Clin. Oncol. 29(15), 2011-2019 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, Issue.15
, pp. 2011-2019
-
-
Van Cutsem, E.1
Kohne, C.H.2
Lang, I.3
-
13
-
-
59949091448
-
Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer
-
Bokemeyer C, Bondarenko I, Makhson A et al. Fluorouracil, leucovorin, and oxaliplatin with and without cetuximab in the first-line treatment of metastatic colorectal cancer. J. Clin. Oncol. 27(5), 663-671 (2009).
-
(2009)
J. Clin. Oncol.
, vol.27
, Issue.5
, pp. 663-671
-
-
Bokemeyer, C.1
Bondarenko, I.2
Makhson, A.3
-
14
-
-
79956310674
-
Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: The OPUS study
-
Bokemeyer C, Bondarenko I, Hartmann JT et al. Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: The OPUS study. Ann. Oncol. 22(7), 1535-1546 (2011).
-
(2011)
Ann. Oncol.
, vol.22
, Issue.7
, pp. 1535-1546
-
-
Bokemeyer, C.1
Bondarenko, I.2
Hartmann, J.T.3
-
15
-
-
78149250536
-
Randomized, Phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: The PRIME study
-
Douillard JY, Siena S, Cassidy J et al. Randomized, Phase III trial of panitumumab with infusional fluorouracil, leucovorin, and oxaliplatin (FOLFOX4) versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer: The PRIME study. J. Clin. Oncol. 28(31), 4697-4705 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.31
, pp. 4697-4705
-
-
Douillard, J.Y.1
Siena, S.2
Cassidy, J.3
-
16
-
-
84862026304
-
Addition of cetuximab to Chemotherapy as first-line treatment for KRAS wild-Type metastatic colorectal cancer: Pooled analysis of the CRYSTAL and OPUS randomised clinical trials
-
Bokemeyer C, Van Cutsem E, Rougier P et al. Addition of cetuximab to Chemotherapy as first-line treatment for KRAS wild-Type metastatic colorectal cancer: Pooled analysis of the CRYSTAL and OPUS randomised clinical trials. Eur. J. Cancer 48(10), 1466-1475 (2012).
-
(2012)
Eur. J. Cancer
, vol.48
, Issue.10
, pp. 1466-1475
-
-
Bokemeyer, C.1
Van Cutsem, E.2
Rougier, P.3
-
17
-
-
84907023716
-
Treatment outcome according to tumor RAS mutation status in OPUS study patients with metastatic colorectal cancer (mCRC randomized to FOLFOX4 with/without cetuximab
-
5s Suppl.), Abstract
-
Bokemeyer C, Kohne C, Ciardiello F et al. Treatment outcome according to tumor RAS mutation status in OPUS study patients with metastatic colorectal cancer (mCRC) randomized to FOLFOX4 with/without cetuximab. J. Clin. Oncol. 32(5s Suppl.), Abstract 3505 (2014).
-
(2014)
J. Clin. Oncol.
, vol.32
, pp. 3505
-
-
Bokemeyer, C.1
Kohne, C.2
Ciardiello, F.3
-
18
-
-
84883680951
-
Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer
-
Douillard JY, Oliner KS, Siena S et al. Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N. Engl. J. Med. 369(11), 1023-1034 (2013).
-
(2013)
N. Engl. J. Med.
, vol.369
, Issue.11
, pp. 1023-1034
-
-
Douillard, J.Y.1
Oliner, K.S.2
Siena, S.3
-
19
-
-
84903694472
-
Final results from PRIME: Randomized Phase 3 study of panitumumab with FOLFOX4 for first-line treatment of metastatic colorectal cancer
-
Douillard JY, Siena S, Cassidy J et al. Final results from PRIME: Randomized Phase 3 study of panitumumab with FOLFOX4 for first-line treatment of metastatic colorectal cancer. Ann. Oncol. 25(7), 1346-1355 (2014).
-
(2014)
Ann. Oncol.
, vol.25
, Issue.7
, pp. 1346-1355
-
-
Douillard, J.Y.1
Siena, S.2
Cassidy, J.3
-
20
-
-
84883480854
-
Analysis of kras/nras and braf mutations in the phase iii prime study of panitumumab (pmab plus folfox versus folfox as first-line treatment (tx) for metastatic colorectal cancer (mcrc)
-
2014. Universidad de Valladolid Suppl.), Abstract
-
Oliner KS, Douillard J-Y, Siena S et al. Analysis of KRAS/NRAS and BRAF mutations in the Phase III PRIME study of panitumumab (pmab) plus FOLFOX versus FOLFOX as first-line treatment (tx) for metastatic colorectal cancer (mCRC). J. Clin. Oncol. 31(Suppl.), Abstract 3511 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, pp. 3511
-
-
Oliner, K.S.1
Douillard, J.-Y.2
Siena, S.3
-
21
-
-
84907023716
-
Treatment outcome according to tumor RAS mutation status in CRYSTAL study patients with metastatic colorectal cancer (mCRC randomized to FOLFIRI with/without cetuximab
-
5s, Suppl.), Abstract 3506
-
Ciardiello F, Lenz HJ, Kohne C et al. Treatment outcome according to tumor RAS mutation status in CRYSTAL study patients with metastatic colorectal cancer (mCRC) randomized to FOLFIRI with/without cetuximab. J. Clin. Oncol. 32(5s, Suppl.), Abstract 3506 (2014).
-
(2014)
J. Clin. Oncol.
, vol.32
-
-
Ciardiello, F.1
Lenz, H.J.2
Kohne, C.3
-
22
-
-
84891516390
-
Use of early tumor shrinkage to predict long-Term outcome in metastatic colorectal cancer treated with cetuximab
-
Piessevaux H, Buyse M, Schlichting M et al. Use of early tumor shrinkage to predict long-Term outcome in metastatic colorectal cancer treated with cetuximab. J. Clin. Oncol. 31(30), 3764-3775 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, Issue.30
, pp. 3764-3775
-
-
Piessevaux, H.1
Buyse, M.2
Schlichting, M.3
-
23
-
-
84871643924
-
Improved early prediction of individual prognosis for patients with mCRC: Joint modeling of tumor shrinkage with volume data for PFS and OS
-
Abstract 3603
-
Mansmann UR, Laubender RP, Sartorius U, Giessen CA, Graser A, Heinemann V. Improved early prediction of individual prognosis for patients with mCRC: Joint modeling of tumor shrinkage with volume data for PFS and OS. J. Clin. Oncol. 30(Suppl. 15), Abstract 3603 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
-
-
Mansmann, U.R.1
Laubender, R.P.2
Sartorius, U.3
Giessen, C.A.4
Graser, A.5
Heinemann, V.6
-
24
-
-
84893673381
-
Deepness of response: A quantitative analysis of its impact on post-progression survival time after first-line treatment in patients with mCRC
-
Abstract 427
-
Mansmann UR, Sartorius U, Laubender RP, Giessen CA, Esser R, Heinemann V. Deepness of response: A quantitative analysis of its impact on post-progression survival time after first-line treatment in patients with mCRC. J. Clin. Oncol. 30(Suppl. 4), Abstract 427 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
-
-
Mansmann, U.R.1
Sartorius, U.2
Laubender, R.P.3
Giessen, C.A.4
Esser, R.5
Heinemann, V.6
-
25
-
-
79959337678
-
Addition of cetuximab to oxaliplatin-based first-line combination Chemotherapy for treatment of advanced colorectal cancer: Results of the randomised Phase 3 MRC COIN trial
-
Maughan TS, Adams RA, Smith CG et al. Addition of cetuximab to oxaliplatin-based first-line combination Chemotherapy for treatment of advanced colorectal cancer: Results of the randomised Phase 3 MRC COIN trial. Lancet 377(9783), 2103-2114 (2011).
-
(2011)
Lancet
, vol.377
, Issue.9783
, pp. 2103-2114
-
-
Maughan, T.S.1
Adams, R.A.2
Smith, C.G.3
-
26
-
-
61449202998
-
The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status: Analysis of a Phase III study of bevacizumab with Chemotherapy in previously untreated metastatic colorectal cancer
-
Hurwitz HI, Yi J, Ince W, Novotny WF, Rosen O. The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status: Analysis of a Phase III study of bevacizumab with Chemotherapy in previously untreated metastatic colorectal cancer. Oncologist 14(1), 22-28 (2009).
-
(2009)
Oncologist
, vol.14
, Issue.1
, pp. 22-28
-
-
Hurwitz, H.I.1
Yi, J.2
Ince, W.3
Novotny, W.F.4
Rosen, O.5
-
27
-
-
42949150908
-
Randomized Phase III study of capecitabine plus oxaliplatin compared with fluorouracil/ folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer
-
Cassidy J, Clarke S, Diaz-Rubio E et al. Randomized Phase III study of capecitabine plus oxaliplatin compared with fluorouracil/ folinic acid plus oxaliplatin as first-line therapy for metastatic colorectal cancer. J. Clin. Oncol. 26(12), 2006-2012 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.12
, pp. 2006-2012
-
-
Cassidy, J.1
Clarke, S.2
Diaz-Rubio, E.3
-
28
-
-
84882937605
-
Randomized comparison of FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment of KRAS wild-Type metastatic colorectal cancer: German AIO study KRK-0306 (FIRE-3)
-
Abstract LBA3506
-
Heinemann V, Fischer Von Weikersthal L, Decker T et al. Randomized comparison of FOLFIRI plus cetuximab versus FOLFIRI plus bevacizumab as first-line treatment of KRAS wild-Type metastatic colorectal cancer: German AIO study KRK-0306 (FIRE-3). J. Clin. Oncol. 31(Suppl. 15), Abstract LBA3506 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
-
-
Heinemann, V.1
Fischer Von Weikersthal, L.2
Decker, T.3
-
29
-
-
84905870196
-
PEAK: A randomized multicenter Phase II study of panitumumab plus modified fluorouracil leucovorin and oxaliplatin (mFOLFOX6) or bevacizumab plus mFOLFOX6 in patients with previously untreated unresectable wild-Type KRAS exon 2 metastatic colorectal cancer
-
Schwartzberg LS, Rivera F, Karthaus M et al. PEAK: A randomized, multicenter Phase II study of panitumumab plus modified fluorouracil, leucovorin, and oxaliplatin (mFOLFOX6) or bevacizumab plus mFOLFOX6 in patients with previously untreated, unresectable, wild-Type KRAS exon 2 metastatic colorectal cancer. J. Clin. Oncol, 32(21), 2240-2247 (2014).
-
(2014)
J. Clin. Oncol
, vol.32
, Issue.21
, pp. 2240-2247
-
-
Schwartzberg, L.S.1
Rivera, F.2
Karthaus, M.3
-
30
-
-
84907027361
-
CALGB/swog 80405: Phase iii trial of irinotecan/5-fu/leucovorin (folfiri) or oxaliplatin/5-fu/leucovorin (mfolfox6) with bevacizumab (bv) or cetuximab (cet) for patients (pts) with kras wild-Type (wt) untreated metastatic adenocarcinoma of the colon or rectum (mcrc)
-
5s, Suppl.), Abstract LBA3
-
Venook A, Niedzwiecki D, Lenz HJ et al. CALGB/SWOG 80405: Phase III trial of irinotecan/5-FU/leucovorin (FOLFIRI) or oxaliplatin/5-FU/leucovorin (mFOLFOX6) with bevacizumab (BV) or cetuximab (CET) for patients (pts) with KRAS wild-Type (wt) untreated metastatic adenocarcinoma of the colon or rectum (MCRC). J. Clin. Oncol. 32(5s, Suppl.), Abstract LBA3 (2014).
-
(2014)
J. Clin. Oncol.
, vol.32
-
-
Venook, A.1
Niedzwiecki, D.2
Lenz, H.J.3
-
31
-
-
33748101222
-
Towards a pan-European consensus on the treatment of patients with colorectal liver metastases
-
Van Cutsem E, Nordlinger B, Adam R et al. Towards a pan-European consensus on the treatment of patients with colorectal liver metastases. Eur. J. Cancer 42(14), 2212-2221 (2006).
-
(2006)
Eur. J. Cancer
, vol.42
, Issue.14
, pp. 2212-2221
-
-
Van Cutsem, E.1
Nordlinger, B.2
Adam, R.3
-
32
-
-
66149155832
-
Combination of surgery and chemotherapy and the role of targeted agents in the treatment of patients with colorectal liver metastases: Recommendations from an expert panel
-
Nordlinger B, Van Cutsem E, Gruenberger T et al. Combination of surgery and chemotherapy and the role of targeted agents in the treatment of patients with colorectal liver metastases: Recommendations from an expert panel. Ann. Oncol. 20(6), 985-992 (2009).
-
(2009)
Ann. Oncol.
, vol.20
, Issue.6
, pp. 985-992
-
-
Nordlinger, B.1
Van Cutsem, E.2
Gruenberger, T.3
-
33
-
-
34548476513
-
Does Chemotherapy prior to liver resection increase the potential for cure in patients with metastatic colorectal cancer? A report from the European colorectal metastases treatment group
-
Nordlinger B, Van Cutsem E, Rougier P et al. Does Chemotherapy prior to liver resection increase the potential for cure in patients with metastatic colorectal cancer? A report from the European Colorectal Metastases Treatment Group. Eur. J. Cancer 43(14), 2037-2045 (2007).
-
(2007)
Eur. J. Cancer
, vol.43
, Issue.14
, pp. 2037-2045
-
-
Nordlinger, B.1
Van Cutsem, E.2
Rougier, P.3
-
34
-
-
23844448040
-
Neoadjuvant treatment of unresectable colorectal liver metastases: Correlation between tumour response and resection rates
-
Folprecht G, Grothey A, Alberts S, Raab HR, Kohne CH. Neoadjuvant treatment of unresectable colorectal liver metastases: Correlation between tumour response and resection rates. Ann. Oncol. 16(8), 1311-1319 (2005).
-
(2005)
Ann. Oncol.
, vol.16
, Issue.8
, pp. 1311-1319
-
-
Folprecht, G.1
Grothey, A.2
Alberts, S.3
Raab, H.R.4
Kohne, C.H.5
-
35
-
-
80053267487
-
Outcome according to metastatic site in patients with KRAS wild-Type tumors: Analysis from the CRYSTAL and OPUS studies
-
Abstract
-
Van Cutsem E, Bokemeyer C, Heeger S, Sartorius U, Rougier P, Kohne C. Outcome according to metastatic site in patients with KRAS wild-Type tumors: Analysis from the CRYSTAL and OPUS studies. J. Clin. Oncol. 29(Suppl. 4), Abstract 472 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 472
-
-
Van Cutsem, E.1
Bokemeyer, C.2
Heeger, S.3
Sartorius, U.4
Rougier, P.5
Kohne, C.6
-
36
-
-
84864424688
-
Efficacy of Chemotherapy plus cetuximab according to metastatic site in KRAS wild-Type metastatic colorectal cancer (mCRC): Analysis of CRYSTAL and OPUS studies
-
Abstract 3576
-
Kohne C, Bokemeyer C, Heeger S, Sartorius U, Rougier P, Van Cutsem E. Efficacy of Chemotherapy plus cetuximab according to metastatic site in KRAS wild-Type metastatic colorectal cancer (mCRC): Analysis of CRYSTAL and OPUS studies. J. Clin. Oncol. 29(Suppl. 15), Abstract 3576 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
-
-
Kohne, C.1
Bokemeyer, C.2
Heeger, S.3
Sartorius, U.4
Rougier, P.5
Van Cutsem, E.6
-
37
-
-
84880736194
-
Randomized controlled trial of cetuximab plus Chemotherapy for patients with KRAS wild-Type unresectable colorectal liver-limited metastases
-
Ye LC, Liu TS, Ren L et al. Randomized controlled trial of cetuximab plus Chemotherapy for patients with KRAS wild-Type unresectable colorectal liver-limited metastases. J. Clin. Oncol. 31(16), 1931-1938 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
, Issue.16
, pp. 1931-1938
-
-
Ye, L.C.1
Liu, T.S.2
Ren, L.3
-
38
-
-
84899900161
-
Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis: The New EPOC randomised controlled trial
-
Primrose J, Falk S, Finch-Jones M et al. Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis: The New EPOC randomised controlled trial. Lancet Oncol. 15(6), 601-611 (2014).
-
(2014)
Lancet Oncol.
, vol.15
, Issue.6
, pp. 601-611
-
-
Primrose, J.1
Falk, S.2
Finch-Jones, M.3
-
39
-
-
84861432557
-
Phase III trial of cetuximab with continuous or intermittent fluorouracil, leucovorin, and oxaliplatin (Nordic FLOX) versus FLOX alone in first-line treatment of metastatic colorectal cancer: The NORDIC-VII study
-
Tveit KM, Guren T, Glimelius B et al. Phase III trial of cetuximab with continuous or intermittent fluorouracil, leucovorin, and oxaliplatin (Nordic FLOX) versus FLOX alone in first-line treatment of metastatic colorectal cancer: The NORDIC-VII study. J. Clin. Oncol. 30(15), 1755-1762 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.15
, pp. 1755-1762
-
-
Tveit, K.M.1
Guren, T.2
Glimelius, B.3
-
40
-
-
84866529371
-
Cetuximab in the first-line treatment of K-ras wild-Type metastatic colorectal cancer: The choice and schedule of fluoropyrimidine matters
-
Ku GY, Haaland BA, De Lima Lopes Jr. G. Cetuximab in the first-line treatment of K-ras wild-Type metastatic colorectal cancer: The choice and schedule of fluoropyrimidine matters. Cancer Chemother. Pharmacol. 70(2), 231-238 (2012).
-
(2012)
Cancer Chemother. Pharmacol.
, vol.70
, Issue.2
, pp. 231-238
-
-
Ku, G.Y.1
Haaland, B.A.2
De Lima Lopes, G.3
-
41
-
-
58049194302
-
Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: A pooled analysis of randomized trials
-
Arkenau HT, Arnold D, Cassidy J et al. Efficacy of oxaliplatin plus capecitabine or infusional fluorouracil/leucovorin in patients with metastatic colorectal cancer: A pooled analysis of randomized trials. J. Clin. Oncol. 26(36), 5910-5917 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.36
, pp. 5910-5917
-
-
Arkenau, H.T.1
Arnold, D.2
Cassidy, J.3
-
42
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-based Chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized Phase III study
-
Saltz LB, Clarke S, Diaz-Rubio E et al. Bevacizumab in combination with oxaliplatin-based Chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized Phase III study. J. Clin. Oncol. 26(12), 2013-2019 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.12
, pp. 2013-2019
-
-
Saltz, L.B.1
Clarke, S.2
Diaz-Rubio, E.3
-
43
-
-
79851496674
-
A Phase II study of capecitabine, oxaliplatin, bevacizumab and cetuximab in the treatment of metastatic colorectal cancer
-
Wong NS, Fernando NH, Nixon AB et al. A Phase II study of capecitabine, oxaliplatin, bevacizumab and cetuximab in the treatment of metastatic colorectal cancer. Anticancer Res. 31(1), 255-261 (2011).
-
(2011)
Anticancer Res.
, vol.31
, Issue.1
, pp. 255-261
-
-
Wong, N.S.1
Fernando, N.H.2
Nixon, A.B.3
-
44
-
-
84894598632
-
Randomized Phase II study of bevacizumab with mFOLFOX6 or FOLFOXIRI in patients with initially unresectable liver metastases from colorectal cancer: Resectability and safety in OLIVIA
-
Abstract 3619
-
Gruenberger T, Bridgewater J, Chau I et al. Randomized, Phase II study of bevacizumab with mFOLFOX6 or FOLFOXIRI in patients with initially unresectable liver metastases from colorectal cancer: Resectability and safety in OLIVIA. J. Clin. Oncol. 31(Suppl. 15), Abstract 3619 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
-
-
Gruenberger, T.1
Bridgewater, J.2
Chau, I.3
-
45
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N. Engl. J. Med. 350(23), 2335-2342 (2004).
-
(2004)
N. Engl. J. Med.
, vol.350
, Issue.23
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
46
-
-
84886092373
-
Cetuximab and Chemotherapy in the treatment of patients with initially nonresectable colorectal (CRC) liver metastases: Long-Term follow-up of the CELIM trial
-
Abstract 3538
-
Folprecht G, Gruenberger T, Bechstein W et al. Cetuximab and Chemotherapy in the treatment of patients with initially 'nonresectable' colorectal (CRC) liver metastases: Long-Term follow-up of the CELIM trial. J. Clin. Oncol. 31(Suppl. 15), Abstract 3538 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
-
-
Folprecht, G.1
Gruenberger, T.2
Bechstein, W.3
-
47
-
-
84859480685
-
The initial change in tumor size predicts response and survival in patients with metastatic colorectal cancer treated with combination Chemotherapy
-
Suzuki C, Blomqvist L, Sundin A et al. The initial change in tumor size predicts response and survival in patients with metastatic colorectal cancer treated with combination Chemotherapy. Ann. Oncol. 23(4), 948-954 (2012).
-
(2012)
Ann. Oncol.
, vol.23
, Issue.4
, pp. 948-954
-
-
Suzuki, C.1
Blomqvist, L.2
Sundin, A.3
-
48
-
-
84878181065
-
Validating the prognostic relevance of initial change in tumor size using a series of therapeutic regimens for patients with metastatic colorectal cancer (mCRC)
-
Abstract 580
-
Mansmann UR, Laubender RP, Giessen CA, Sartorius U, Heinemann V. Validating the prognostic relevance of initial change in tumor size using a series of therapeutic regimens for patients with metastatic colorectal cancer (mCRC). J. Clin. Oncol. 30(Suppl. 4), Abstract 580 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
-
-
Mansmann, U.R.1
Laubender, R.P.2
Giessen, C.A.3
Sartorius, U.4
Heinemann, V.5
-
49
-
-
69449084698
-
Radiological tumor size decrease at week 6 is a potent predictor of outcome in chemorefractory metastatic colorectal cancer treated with cetuximab (BOND trial)
-
Piessevaux H, Buyse M, De Roock W et al. Radiological tumor size decrease at week 6 is a potent predictor of outcome in chemorefractory metastatic colorectal cancer treated with cetuximab (BOND trial). Ann. Oncol. 20(8), 1375-1382 (2009).
-
(2009)
Ann. Oncol.
, vol.20
, Issue.8
, pp. 1375-1382
-
-
Piessevaux, H.1
Buyse, M.2
De Roock, W.3
-
50
-
-
84870843463
-
Early tumor shrinkage and long-Term outcome in metastatic colorectal cancer (mCRC): Assessment of predictive utility across treatment arms in the CRYSTAL and OPUS studies
-
Abstract 3572
-
Piessevaux H, Van Cutsem E, Bokemeyer C, Schlichting M, Heeger S, Tejpar S. Early tumor shrinkage and long-Term outcome in metastatic colorectal cancer (mCRC): Assessment of predictive utility across treatment arms in the CRYSTAL and OPUS studies. J. Clin. Oncol. 29(Suppl. 15), Abstract 3572 (2011).
-
(2011)
J. Clin. Oncol.
, vol.29
-
-
Piessevaux, H.1
Van Cutsem, E.2
Bokemeyer, C.3
Schlichting, M.4
Heeger, S.5
Tejpar, S.6
-
51
-
-
84884674438
-
FOLFOXIRI/bevacizumab (bev versus folfiri/bev as first-line treatment in unresectable metastatic colorectal cancer (mcrc) patients (pts): Results of the phase iii tribe trial by gono group
-
Abstract 3505
-
Falcone A, Cremolini C, Masi G et al. FOLFOXIRI/bevacizumab (bev) versus FOLFIRI/bev as first-line treatment in unresectable metastatic colorectal cancer (mCRC) patients (pts): Results of the Phase III TRIBE trial by GONO group. J. Clin. Oncol. 31(Suppl. 15), Abstract 3505 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
-
-
Falcone, A.1
Cremolini, C.2
Masi, G.3
-
52
-
-
84893673381
-
Deepness of Response: A quantitative analysis of its impact on post-progression survival time after first-line treatment in patients with mCRC
-
Abstract 427
-
Mansmann UR, Sartorius U, Laubender RP, Giessen CA, Esser R, Heinemann V. Deepness of Response: A quantitative analysis of its impact on post-progression survival time after first-line treatment in patients with mCRC. J. Clin. Oncol. 30(Suppl. 4), Abstract 427 (2013).
-
(2013)
J. Clin. Oncol.
, vol.30
-
-
Mansmann, U.R.1
Sartorius, U.2
Laubender, R.P.3
Giessen, C.A.4
Esser, R.5
Heinemann, V.6
-
53
-
-
84893673381
-
Quantitative analysis of the impact of deepness of response on post-progression survival time following first-line treatment in patients with mCRC
-
Suppl.), Abstract 3630
-
Mansmann UR, Sartorius U, Laubender RP, Giessen CA, Esser R, Heinemann V. Quantitative analysis of the impact of deepness of response on post-progression survival time following first-line treatment in patients with mCRC. J. Clin. Oncol. 31(Suppl.), Abstract 3630 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
-
-
Mansmann, U.R.1
Sartorius, U.2
Laubender, R.P.3
Giessen, C.A.4
Esser, R.5
Heinemann, V.6
-
54
-
-
84893673381
-
Quantitative analysis of the impact of deepness of response on post-progression survival time following first-line treatment in patients with mCRC
-
Suppl.), Abstract O-0009
-
Mansmann UR, Sartorius U, Laubender RP, Giessen CA, Esser R, Heinemann V. Quantitative analysis of the impact of deepness of response on post-progression survival time following first-line treatment in patients with mCRC. Ann. Oncol (Suppl.), Abstract O-0009 (2013).
-
(2013)
Ann. Oncol
-
-
Mansmann, U.R.1
Sartorius, U.2
Laubender, R.P.3
Giessen, C.A.4
Esser, R.5
Heinemann, V.6
-
55
-
-
84898666033
-
Analysis of kras/nras and braf mutations in fire-3: A randomized phase iii study of folfiri plus cetuximab or bevacizumab as first-line treatment for wild-Type (wt) kras (exon 2) metastatic colorectal cancer (mcrc) patients
-
Brussels, Belgium, Abstract 17
-
Stintzing S, Jung A, Rossius L et al. Analysis of KRAS/NRAS and BRAF mutations in FIRE-3: A randomized Phase III study of FOLFIRI plus cetuximab or bevacizumab as first-line treatment for wild-Type (WT) KRAS (exon 2) metastatic colorectal cancer (mCRC) patients. European Cancer Congress 2013, Brussels, Belgium, Abstract 17 (2013).
-
(2013)
European Cancer Congress 2013
-
-
Stintzing, S.1
Jung, A.2
Rossius, L.3
-
56
-
-
84911460699
-
Independent radiological evaluation of objective response early tumor shrinkage and depth of response in FIRE-3 (AIO KRK-0306)
-
Abstract O-0030
-
Heinemann V, Modest DP, Fischer Von Weikersthal L et al. Independent radiological evaluation of objective response early tumor shrinkage and depth of response in FIRE-3 (AIO KRK-0306). Ann. Oncol. 25(Suppl. 2), Abstract O-0030 (2014).
-
(2014)
Ann. Oncol.
, vol.25
-
-
Heinemann, V.1
Modest, D.P.2
Fischer Von Weikersthal, L.3
-
57
-
-
34249000361
-
Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: The gruppo oncologico nord ovest
-
Falcone A, Ricci S, Brunetti I et al. Phase III trial of infusional fluorouracil, leucovorin, oxaliplatin, and irinotecan (FOLFOXIRI) compared with infusional fluorouracil, leucovorin, and irinotecan (FOLFIRI) as first-line treatment for metastatic colorectal cancer: The Gruppo Oncologico Nord Ovest. J. Clin. Oncol. 25(13), 1670-1676 (2007).
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.13
, pp. 1670-1676
-
-
Falcone, A.1
Ricci, S.2
Brunetti, I.3
-
58
-
-
84891629487
-
FOLFOXIRI plus bevacizumab as first-line treatment in BRAF mutant metastatic colorectal cancer
-
Loupakis F, Cremolini C, Salvatore L et al. FOLFOXIRI plus bevacizumab as first-line treatment in BRAF mutant metastatic colorectal cancer. Eur. J. Cancer 50(1), 57-63 (2014).
-
(2014)
Eur. J. Cancer
, vol.50
, Issue.1
, pp. 57-63
-
-
Loupakis, F.1
Cremolini, C.2
Salvatore, L.3
-
59
-
-
36849016055
-
A pooled safety and efficacy analysis examining the effect of performance status (PS) on outcomes in nine first-line treatment (rx) trials (cts) of 6,286 patients (pts) with metastatic colorectal cancer (mCRC)
-
Abstract 4011
-
Goldberg RM, Kohne CH, Seymour MT et al. A pooled safety and efficacy analysis examining the effect of performance status (PS) on outcomes in nine first-line treatment (rx) trials (cts) of 6,286 patients (pts) with metastatic colorectal cancer (mCRC). J. Clin. Oncol. 25(18S), Abstract 4011 (2007).
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.18
-
-
Goldberg, R.M.1
Kohne, C.H.2
Seymour, M.T.3
-
60
-
-
84872115684
-
Quality of life analysis in patients with KRAS wild-Type metastatic colorectal cancer treated first-line with cetuximab plus irinotecan, fluorouracil and leucovorin
-
Lang I, Kohne CH, Folprecht G et al. Quality of life analysis in patients with KRAS wild-Type metastatic colorectal cancer treated first-line with cetuximab plus irinotecan, fluorouracil and leucovorin. Eur. J. Cancer 49(2), 439-448 (2013).
-
(2013)
Eur. J. Cancer
, vol.49
, Issue.2
, pp. 439-448
-
-
Lang, I.1
Kohne, C.H.2
Folprecht, G.3
-
61
-
-
20544471876
-
Combined analysis of efficacy: The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
-
Kabbinavar FF, Hambleton J, Mass RD, Hurwitz HI, Bergsland E, Sarkar S. Combined analysis of efficacy: The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer. J. Clin. Oncol. 23(16), 3706-3712 (2005).
-
(2005)
J. Clin. Oncol.
, vol.23
, Issue.16
, pp. 3706-3712
-
-
Kabbinavar, F.F.1
Hambleton, J.2
Mass, R.D.3
Hurwitz, H.I.4
Bergsland, E.5
Sarkar, S.6
-
62
-
-
77955497309
-
Capecitabine, bevacizumab, and mitomycin in first-line treatment of metastatic colorectal cancer: Results of the Australasian gastrointestinal trials group randomized Phase III MAX study
-
Tebbutt NC, Wilson K, Gebski VJ et al. Capecitabine, bevacizumab, and mitomycin in first-line treatment of metastatic colorectal cancer: Results of the Australasian gastrointestinal trials group randomized Phase III MAX study. J. Clin. Oncol. 28(19), 3191-3198 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.19
, pp. 3191-3198
-
-
Tebbutt, N.C.1
Wilson, K.2
Gebski, V.J.3
-
63
-
-
77956083776
-
Treatment of colorectal cancer with and without bevacizumab: A Phase III study
-
Stathopoulos GP, Batziou C, Trafalis D et al. Treatment of colorectal cancer with and without bevacizumab: A Phase III study. Oncology 78(5-6), 376-381 (2010).
-
(2010)
Oncology
, vol.78
, Issue.5-6
, pp. 376-381
-
-
Stathopoulos, G.P.1
Batziou, C.2
Trafalis, D.3
-
64
-
-
66149120036
-
Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: The BEAT study
-
Van Cutsem E, Rivera F, Berry S et al. Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: The BEAT study. Ann. Oncol. 20(11), 1842-1847 (2009).
-
(2009)
Ann. Oncol.
, vol.20
, Issue.11
, pp. 1842-1847
-
-
Van Cutsem, E.1
Rivera, F.2
Berry, S.3
-
65
-
-
67650996205
-
Phase IV study of bevacizumab in combination with infusional fluorouracil, leucovorin and irinotecan (FOLFIRI) in first-line metastatic colorectal cancer
-
Sobrero A, Ackland S, Clarke S et al. Phase IV study of bevacizumab in combination with infusional fluorouracil, leucovorin and irinotecan (FOLFIRI) in first-line metastatic colorectal cancer. Oncology 77(2), 113-119 (2009).
-
(2009)
Oncology
, vol.77
, Issue.2
, pp. 113-119
-
-
Sobrero, A.1
Ackland, S.2
Clarke, S.3
-
66
-
-
39149108869
-
Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Updated results from the BICC-C study
-
Fuchs CS, Marshall J, Barrueco J. Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Updated results from the BICC-C study. J. Clin. Oncol. 26(4), 689-690 (2008).
-
(2008)
J. Clin. Oncol.
, vol.26
, Issue.4
, pp. 689-690
-
-
Fuchs, C.S.1
Marshall, J.2
Barrueco, J.3
-
67
-
-
36048960109
-
Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Results from the BICC-C Study
-
Fuchs CS, Marshall J, Mitchell E et al. Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Results from the BICC-C Study. J. Clin. Oncol. 25(30), 4779-4786 (2007).
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.30
, pp. 4779-4786
-
-
Fuchs, C.S.1
Marshall, J.2
Mitchell, E.3
-
68
-
-
34848835988
-
Bevacizumab (Bev) in combination with XELOX or FOLFOX4: Updated efficacy results from XELOX-1/ NO16966, a randomized Phase III trial in first-line metastatic colorectal cancer
-
Abstract 4028
-
Saltz L, Clarke S, Diaz-Rubio E et al. Bevacizumab (Bev) in combination with XELOX or FOLFOX4: Updated efficacy results from XELOX-1/ NO16966, a randomized Phase III trial in first-line metastatic colorectal cancer. J. Clin. Oncol. 25(Suppl. 18), Abstract 4028 (2007).
-
(2007)
J. Clin. Oncol.
, vol.25
-
-
Saltz, L.1
Clarke, S.2
Diaz-Rubio, E.3
-
69
-
-
84892147161
-
Bevacizumab + capecitabine as maintenance therapy after initial bevacizumab + xelox treatment in previously untreated patients with metastatic colorectal cancer: Phase iii 'stop and go' study results-A turkish oncology group trial
-
Yalcin S, Uslu R, Dane F et al. Bevacizumab + capecitabine as maintenance therapy after initial bevacizumab + XELOX treatment in previously untreated patients with metastatic colorectal cancer: Phase III 'Stop and Go' study results-A Turkish Oncology Group Trial. Oncology 85(6), 328-335 (2013).
-
(2013)
Oncology
, vol.85
, Issue.6
, pp. 328-335
-
-
Yalcin, S.1
Uslu, R.2
Dane, F.3
-
70
-
-
84902247358
-
Final results and subgroup analyses of the Phase 3 CAIRO3 study: Maintenance treatment with capecitabine + bevacizumab versus observation after induction treatment with Chemotherapy + bevacizumab in metastatic colorectal cancer (mCRC)
-
Abstract 3504
-
Koopman M, Simkens L, May AM, Mol L, Van Tinteren H, Punt CJA. Final results and subgroup analyses of the Phase 3 CAIRO3 study: Maintenance treatment with capecitabine + bevacizumab versus observation after induction treatment with Chemotherapy + bevacizumab in metastatic colorectal cancer (mCRC). J. Clin. Oncol. 32(Suppl. 5), Abstract 3504 (2014).
-
(2014)
J. Clin. Oncol.
, vol.32
-
-
Koopman, M.1
Simkens, L.2
May, A.M.3
Mol, L.4
Van Tinteren, H.5
Punt, C.J.A.6
-
71
-
-
84884700039
-
Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): An open-label, randomised Phase 3 trial
-
Cunningham D, Lang I, Marcuello E et al. Bevacizumab plus capecitabine versus capecitabine alone in elderly patients with previously untreated metastatic colorectal cancer (AVEX): An open-label, randomised Phase 3 trial. Lancet Oncol. 14(11), 1077-1085 (2013).
-
(2013)
Lancet Oncol.
, vol.14
, Issue.11
, pp. 1077-1085
-
-
Cunningham, D.1
Lang, I.2
Marcuello, E.3
-
72
-
-
84871720057
-
Continuation of bevacizumab after first progression in metastatic colorectal cancer (ML18147): A randomised Phase 3 trial
-
Bennouna J, Sastre J, Arnold D et al. Continuation of bevacizumab after first progression in metastatic colorectal cancer (ML18147): A randomised Phase 3 trial. Lancet Oncol. 14(1), 29-37 (2013).
-
(2013)
Lancet Oncol.
, vol.14
, Issue.1
, pp. 29-37
-
-
Bennouna, J.1
Sastre, J.2
Arnold, D.3
-
73
-
-
84867047384
-
Addition of aflibercept to fluorouracil, leucovorin, and irinotecan improves survival in a Phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen
-
Van Cutsem E, Tabernero J, Lakomy R et al. Addition of aflibercept to fluorouracil, leucovorin, and irinotecan improves survival in a Phase III randomized trial in patients with metastatic colorectal cancer previously treated with an oxaliplatin-based regimen. J. Clin. Oncol. 30(28), 3499-3506 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
, Issue.28
, pp. 3499-3506
-
-
Van Cutsem, E.1
Tabernero, J.2
Lakomy, R.3
-
74
-
-
84870965175
-
Results from VELOUR, a Phase 3 study of aflibercept (A) versus placebo (pbo) in combination with FOLFIRI for the treatment of patients (pt) with previously treated metastatic colorectal cancer (MCRC)
-
Tabernero J, Van Cutsem E, Lakomy R et al. Results from VELOUR, a Phase 3 study of aflibercept (A) versus placebo (pbo) in combination with FOLFIRI for the treatment of patients (pt) with previously treated metastatic colorectal cancer (MCRC). Eur. J. Cancer 47(Suppl. 2), 5 (2011).
-
(2011)
Eur. J. Cancer 47(Suppl.
, vol.2
, Issue.5
-
-
Tabernero, J.1
Van Cutsem, E.2
Lakomy, R.3
-
75
-
-
84893335909
-
Second-line chemotherapy (CT) with or without bevacizumab (BV) in metastatic colorectal cancer (mCRC) patients (pts) who progressed to a first-line treatment containing BV: Updated results of the Phase III BEBYP trial by the Gruppo Oncologico Nord Ovest (GONO)
-
Abstract 3615
-
Masi G, Loupakis F, Salvatore L et al. Second-line chemotherapy (CT) with or without bevacizumab (BV) in metastatic colorectal cancer (mCRC) patients (pts) who progressed to a first-line treatment containing BV: Updated results of the Phase III 'BEBYP' trial by the Gruppo Oncologico Nord Ovest (GONO). J. Clin. Oncol. 31(Suppl. 15), Abstract 3615 (2013).
-
(2013)
J. Clin. Oncol.
, vol.31
-
-
Masi, G.1
Loupakis, F.2
Salvatore, L.3
-
76
-
-
34248173883
-
Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200
-
Giantonio BJ, Catalano PJ, Meropol NJ et al. Bevacizumab in combination with oxaliplatin, fluorouracil, and leucovorin (FOLFOX4) for previously treated metastatic colorectal cancer: Results from the Eastern Cooperative Oncology Group Study E3200. J. Clin. Oncol. 25(12), 1539-1544 (2007).
-
(2007)
J. Clin. Oncol.
, vol.25
, Issue.12
, pp. 1539-1544
-
-
Giantonio, B.J.1
Catalano, P.J.2
Meropol, N.J.3
-
77
-
-
3242720345
-
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
-
Cunningham D, Humblet Y, Siena S et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N. Engl. J. Med. 351(4), 337-345 (2004).
-
(2004)
N. Engl. J. Med.
, vol.351
, Issue.4
, pp. 337-345
-
-
Cunningham, D.1
Humblet, Y.2
Siena, S.3
-
79
-
-
54949085398
-
K-ras mutations and benefit from cetuximab in advanced colorectal cancer
-
Karapetis CS, Khambata-Ford S, Jonker DJ et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N. Engl. J. Med. 359(17), 1757-1765 (2008).
-
(2008)
N. Engl. J. Med.
, vol.359
, Issue.17
, pp. 1757-1765
-
-
Karapetis, C.S.1
Khambata-Ford, S.2
Jonker, D.J.3
-
80
-
-
78149239651
-
Randomized Phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer
-
Peeters M, Price TJ, Cervantes A et al. Randomized Phase III study of panitumumab with fluorouracil, leucovorin, and irinotecan (FOLFIRI) compared with FOLFIRI alone as second-line treatment in patients with metastatic colorectal cancer. J. Clin. Oncol. 28(31), 4706-4713 (2010).
-
(2010)
J. Clin. Oncol.
, vol.28
, Issue.31
, pp. 4706-4713
-
-
Peeters, M.1
Price, T.J.2
Cervantes, A.3
-
81
-
-
84868526153
-
Effects of prior bevacizumab (B use on outcomes from the VELOUR study: A Phase III study of aflibercept (Afl) and FOLFIRI in patients (pts) with metastatic colorectal cancer (mCRC) after failure of an oxaliplatin regimen
-
Abstract 3505
-
Allegra CJ, Lakomy R, Tabernero J et al. Effects of prior bevacizumab (B) use on outcomes from the VELOUR study: A Phase III study of aflibercept (Afl) and FOLFIRI in patients (pts) with metastatic colorectal cancer (mCRC) after failure of an oxaliplatin regimen. J. Clin. Oncol. 30(Suppl. 15), Abstract 3505 (2012).
-
(2012)
J. Clin. Oncol.
, vol.30
-
-
Allegra, C.J.1
Lakomy, R.2
Tabernero, J.3
-
82
-
-
84873808521
-
Bevacizumab plus chemotherapy as salvage treatment in chemorefractory patients with metastatic colorectal cancer
-
Geva R, Vecchione L, Tejpar S, Piessevaux H, Van Cutsem E, Prenen H. Bevacizumab plus chemotherapy as salvage treatment in chemorefractory patients with metastatic colorectal cancer. Onco Targets Ther. 6, 53-58 (2013).
-
(2013)
Onco Targets Ther.
, vol.6
, pp. 53-58
-
-
Geva, R.1
Vecchione, L.2
Tejpar, S.3
Piessevaux, H.4
Van Cutsem, E.5
Prenen, H.6
-
83
-
-
84874725276
-
The development of regorafenib and its current and potential future role in cancer therapy
-
Davis SL, Eckhardt SG, Messersmith WA, Jimeno A. The development of regorafenib and its current and potential future role in cancer therapy. Drugs Today (Barc) 49(2), 105-115 (2013).
-
(2013)
Drugs Today (Barc
, vol.49
, Issue.2
, pp. 105-115
-
-
Davis, S.L.1
Eckhardt, S.G.2
Messersmith, W.A.3
Jimeno, A.4
-
84
-
-
84872921660
-
Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): An international, multicentre, randomised, placebo-controlled, Phase 3 trial
-
Grothey A, Van Cutsem E, Sobrero A et al. Regorafenib monotherapy for previously treated metastatic colorectal cancer (CORRECT): An international, multicentre, randomised, placebo-controlled, Phase 3 trial. Lancet 381(9863), 303-312 (2013).
-
(2013)
Lancet
, vol.381
, Issue.9863
, pp. 303-312
-
-
Grothey, A.1
Van Cutsem, E.2
Sobrero, A.3
-
85
-
-
84874641687
-
Metastatic colon cancer, version 3.2013: Featured updates to the NCCN Guidelines
-
Benson AB 3rd, Bekaii-Saab T, Chan E et al. Metastatic colon cancer, version 3.2013: Featured updates to the NCCN Guidelines. J. Natl Compr. Canc. Netw. 11(2), 141-152 (2013).
-
(2013)
J. Natl Compr. Canc. Netw.
, vol.11
, Issue.2
, pp. 141-152
-
-
Benson, A.B.1
Bekaii-Saab, T.2
Chan, E.3
-
86
-
-
1342290189
-
FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
-
Tournigand C, Andre T, Achille E et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study. J. Clin. Oncol. 22(2), 229-237 (2004).
-
(2004)
J. Clin. Oncol.
, vol.22
, Issue.2
, pp. 229-237
-
-
Tournigand, C.1
Andre, T.2
Achille, E.3
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