Ultrafast quantification of β-lactam antibiotics in human plasma using UPLC-MS/MS

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 978-979, Issue , 2015, Pages 89-94

  Carlier, Mieke ^a   Stove, Veronique ^a,b   De Waele, Jan J ^a   Verstraete, Alain G ^a,b  

^a GHENT UNIVERSITY   (Belgium)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Beta lactam antibiotics; Therapeutic drug monitoring; UPLC MS MS

Indexed keywords

CHROMATOGRAPHIC ANALYSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PATIENT MONITORING; POSITIVE IONS;

BETA-LACTAMS; CHROMATOGRAPHIC METHODS; CHROMATOGRAPHIC SEPARATIONS; PLASMA CONCENTRATION; PROTEIN PRECIPITATION; TANDEM MASS SPECTROMETRIC DETECTION; THERAPEUTIC DRUG MONITORING; UPLC-MS/MS;

ANTIBIOTICS;

ACETONITRILE; AMMONIUM ACETATE; AMOXICILLIN; CEFTAZIDIME; CEFUROXIME; FORMIC ACID; MEROPENEM; METHANOL; PIPERACILLIN; WATER; ANTIINFECTIVE AGENT; BETA LACTAM;

ACCURACY; ARTICLE; CENTRIFUGATION; CHROMATOGRAPHY; CONTROLLED STUDY; DILUTION; ELECTROSPRAY; ELUTION; HUMAN; LIMIT OF QUANTITATION; NONHUMAN; PLASMA; PRECIPITATION; SUPERNATANT; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAFAST QUANTIFICATION; ANIMAL; BLOOD; BOVINE; DRUG MONITORING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIMIT OF DETECTION; PROCEDURES; REPRODUCIBILITY; STATISTICAL MODEL;

ANIMALS; ANTI-BACTERIAL AGENTS; BETA-LACTAMS; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG MONITORING; HUMANS; LIMIT OF DETECTION; LINEAR MODELS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 84919800599     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2014.11.034     Document Type: Article

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