Quantification of seven β-lactam antibiotics and two β-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method

International Journal of Antimicrobial Agents

Volumn 40, Issue 5, 2012, Pages 416-422

  Carlier, Mieke ^a   Stove, Veronique ^a   Roberts, Jason A ^b   Van De Velde, Eric ^a   De Waele, Jan J ^a   Verstraete, Alain G ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Lactam antibiotics; Therapeutic drug monitoring; UPLC MS MS

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; CEFAZOLIN; CEFTAZIDIME; CEFUROXIME; CLAVULANIC ACID; MEROPENEM; PIPERACILLIN; TAZOBACTAM;

ACCURACY; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; HUMAN; LIMIT OF QUANTITATION; PRIORITY JOURNAL; PROCESS DEVELOPMENT; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; VALIDATION STUDY;

ANTI-BACTERIAL AGENTS; BETA-LACTAMS; CHROMATOGRAPHY, LIQUID; ENZYME INHIBITORS; HUMAN EXPERIMENTATION; HUMANS; PLASMA; TANDEM MASS SPECTROMETRY;

EID: 84867402382     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2012.06.022     Document Type: Article

References (24)

1. J.-L. Vincent, J. Rello, J. Marshall, E. Silva, A. Anzueto, and C.D. Martin International study of the prevalence and outcomes of infection in intensive care units JAMA 302 2009 2323 2329
2. L. Leibovici, I. Shraga, M. Drucker, H. Konigsberger, Z. Samra, and S.D. Pitlik The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection J Intern Med 244 1998 379 386
3. J.D. Turnidge The pharmacodynamics of β-lactams Clin Infect Dis 27 1998 10 22
4. J.A. Roberts, and J. Lipman Pharmacokinetic issues for antibiotics in the critically ill patient Crit Care Med 37 2009 840 851
5. J.A. Roberts, M. Ulldemolins, M.S. Roberts, B. McWhinney, J. Ungerer, and D.L. Paterson Therapeutic drug monitoring of β-lactams in critically ill patients: proof of concept Int J Antimicrob Agents 36 2010 332 339
6. F.S. Taccone, P.-F. Laterre, T. Dugernier, H. Spapen, I. Delattre, and X. Wittebole Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock Crit Care 14 2010 R126
7. N. Blondiaux, F. Wallet, R. Favory, T. Onimus, S. Nseir, and R.J. Courcol Daily serum piperacillin monitoring is advisable in critically ill patients Int J Antimicrob Agents 35 2010 500 503
8. J.A. Roberts, R. Norris, D.L. Paterson, and J.H. Martin Therapeutic drug monitoring of antimicrobials Br J Clin Pharmacol 73 2012 27 36
9. T. Reyns, S. De Baere, S. Croubels, and P. De Backer Determination of clavulanic acid in calf plasma by liquid chromatography tandem mass spectrometry J Mass Spectrom 41 2006 1414 1420
10. B.K. Matuszewski, M.L. Constanzer, and C.M. Chavez-Eng Strategies for the assessment of matrix effect in quantitative bioanalytical methods based on HPLC-MS/MS Anal Chem 75 2003 3019 3030
11. A.M. Almeida, M.M. Castel-Branco, and A.C. Falcao Linear regression for calibration lines revisited: weighting schemes for bioanalytical methods J Chromatogr B Analyt Technol Biomed Life Sci 774 2002 215 222
12. International Conference on Harmonization (ICH) Validation of analytical methods: methodology ICH Q2 B 1996 ICH Geneva, Switzerland
13. European Medicines Agency (EMEA). Guideline on bioanalytical method validation. EMEA; 2011. EMEA/CHMP/EWP/192217/2009. http://www.ema.europa.eu/ docs/en-GB/document-library/Scientific-guideline/2011/08/WC500109686.pdf [accessed 30.03.12].
14. F. Peters Method validation using LC-MS A. Polettini, Application of LC-MS in toxicology 2006 Pharmaceutical Press London, UK
15. V.F. Samanidou, and E.G. Karageorgou On the use of Kinetex™-C18 core-shell 2.6 μm stationary phase to the multiclass determination of antibiotics Drug Test Anal 3 2011 234 244
16. T. Ohmori, A. Suzuki, T. Niwa, H. Ushikoshi, K. Shirai, and S. Yoshida Simultaneous determination of eight β-lactam antibiotics in human serum by liquid chromatography-tandem mass spectrometry J Chromatogr B Analyt Technol Biomed Life Sci 879 2011 1038 1042
17. E. Dailly, R. Bouquié, G. Deslandes, P. Jolliet, and R. Le Floch A liquid chromatography assay for a quantification of doripenem, ertapenem, imipenem, meropenem concentrations in human plasma: application to a clinical pharmacokinetic study J Chromatogr B Analyt Technol Biomed Life Sci 879 2011 1137 1142
18. B.C. McWhinney, S.C. Wallis, T. Hillister, J.A. Roberts, J. Lipman, and J.P.J. Ungerer Analysis of 12 β-lactam antibiotics in human plasma by HPLC with ultraviolet detection J Chromatogr B Analyt Technol Biomed Life Sci 878 2010 2039 2043
19. V.F. Samanidou, E.N. Evaggelopoulou, and I.N. Papadoyannis Development of a validated HPLC method for the determination of four penicillin antibiotics in pharmaceuticals and human biological fluids J Sep Sci 29 2006 1550 1560
20. C.S. Wu, J.L. Zhang, Y.L. Qiao, Y.L. Wang, and Z.R. Chen Simultaneous determination of 14 β-lactam antibiotics in cosmetic products by liquid chromatography tandem mass spectrometry method Chin Chem Lett 22 2011 334 337
21. M.-C. Verdier, O. Tribut, P. Tattevin, Y. Le Tulzo, C. Michelet, and D. Bentué-Ferrer Simultaneous determination of 12 β-lactam antibiotics in human plasma by high-performance liquid chromatography with UV detection: application to therapeutic drug monitoring Antimicrob Agents Chemother 55 2011 4873 4879
22. K.H. Yoon, S.Y. Lee, W. Kim, J.S. Park, and H.J. Kim Simultaneous determination of amoxicillin and clavulanic acid in human plasma by HPLC-ESI mass spectrometry J Chromatogr B Analyt Technol Biomed Life Sci 813 2004 121 127
23. R. Denooz, and C. Charlier Simultaneous determination of five β-lactam antibiotics (cefepim, ceftazidim, cefuroxim, meropenem and piperacillin) in human plasma by high-performance liquid chromatography with ultraviolet detection J Chromatogr B Analyt Technol Biomed Life Sci 864 2008 161 167
24. European Committee on Antimicrobial Susceptibility Testing (EUCAST). Antimicrobial wild type distributions of microorganisms. EUCAST; 2012. http://mic.eucast.org/Eucast2/SearchController/search.jsp?action=init [accessed 30.03.12].