Effect of smoking on serum xanthine oxidase, malondialdehyde, ascorbic acid and α-tocopherol levels in healthy male subjects

Pakistan Journal of Medical Sciences

Volumn 31, Issue 1, 2015, Pages 146-149

  Shah, Ali Akbar ^a   Khand, Fatehuddin ^a   Khand, Tayyab Uddin ^b  

^a ISRA UNIVERSITY   (Pakistan)

^b Department of Anatomy Indus Medical College   (Pakistan)

Author keywords

Alpha Tocopherol; Ascorbic acid; Malondialdehyde; Smokers; Xanthine oxidase

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; MALONALDEHYDE; REACTIVE OXYGEN METABOLITE; XANTHINE OXIDASE;

ADULT; ARTICLE; BLOOD SAMPLING; COMPARATIVE STUDY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; ENZYME BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; POPULATION RESEARCH; SMOKING; SPECTROPHOTOMETRY; VITAMIN BLOOD LEVEL; YOUNG ADULT;

EID: 84919795446     PISSN: 1682024X     EISSN: None     Source Type: Journal    
DOI: 10.12669/pjms.311.6148     Document Type: Article

References (23)

1. U. S Department of Health and Human Services. The Health consequences of smoking-50 years of progress: A report of the Surgeon General Atlanta, GA: U. S. Department of Health and Human Services, Centers for disease control and prevention, National center for chronic disease prevention and health promotion, Office on smoking and health, 2014.
2. Saha SP, Bhalla DK, Whayne TF Jr., and Gairola CG. Cigarette smoke and adverse health effects: An overview of research trends and future needs. Int J Angiol. 2007; 16(3): 77-83.
3. Schumacher JN, Green CR, Best FW, Newell MP. Smoke composition: an extensive investigation of the water soluble portion of cigarette smoke. J Agric Food Chem. 1997; 25: 310-320.
4. Sen S, Chakraborty R, Sridhar C, Reddy YSR, De B. Free radicals, antioxidants, diseases and phytomedicines: Current status and future prospect. Int J Pharma Sci Rev Res. 2010; 3(1): 91-100.
5. Lobo V, Patil A, Phatak A and Chandra N. Free radicals, antioxidants and functional foods: Impact on human health. Pharmacogn Rev. 2010; 4: 118-126.
6. Birben E, Sahiner UM, Sackesen C, Erzurum S, Kalayci O. Oxidative stress and antioxidant defense. World Allergy Organ J. 2012; 5: 9-19.
7. Li X, Fang P, Mai J, Choi ET, Wang H, Yang XF. Targeting mitochondrial reactive oxygen species as novel therapy for inflammatory diseases and cancers. J Hematol Oncol. 2013; 6: 1-19.
8. Devasagayam T, Boloor KK. Methods for estimating lipid peroxidation: an analysis of merits and demerits. Indian J Biochem Biophys. 2003; 40: 300-308.
9. Fiskin K, Ozkan A, Ayhan A. Protective effect of selenium and vitamin E on lipid peroxidation in smoke-exposed male mice. Turk J Biochem. 2005; 30(3): 232-235.
10. Chow CK. Role of vitamin E in cellular antioxidant defense. Curr Chem Biol. 2009; 3(2): 197-202.
11. Duthie GG, Arthur JR, James, WP. Effects of smoking and vitamin E on blood antioxidant status. Am J Clin Nutr. 1991; 53(4 Suppl): 1061S-1063S.
12. Kelly G. The interaction of cigarette smoking and antioxidants. Part III: ascorbic acid. Altern Med Rev. 2003; 8(1): 43-54.
13. Raghuvanshi R, Kaul A, Bhakuni P, Mishra A, Misra MK. Xanthine oxidase as a marker of myocardial infarction. Indian J Clin Biochem. 2007; 22(2): 90-92. doi: 10. 1007/BF02913321.
14. Pham-Huy LA, He H, Pham-Huy C. Free radicals, antioxidants in disease and health. Int J Biomed Sci. 2008; 4(2): 89-96.
15. Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M. Free radicals, metals and antioxidants in oxidative stressinduced cancer. Chem Biointeract. 2006; 160(1): 38-40.
16. Chaitanya KV, Pathan AAK, Mazumdar SS, Chakravarthi GP, Parine N, Bobbarala V. Role of oxidative stress in human health: An overview. J Pharm Res. 2010; 3: 1330-1333.
17. Bernhard D and Wang XL. Smoking, oxidative stress and cardiovascular diseases-Do anti-oxidative therapies fail? Curr Med Chem. 2007; 14(16): 1703-1712.
18. Mehboobali N, Iqbal MP. A simple micromethod for determination of plasma levels of alpha tocopherol (Vitamin E) in Pakistani normal adults. Pak J Pharm Sci. 2008; 121(4): 361-365.
19. McCormick DB, Green HL. Vitamins. In: Burtis CA, Ashwood ER Eds. Fundamentals of Clinical Chemistry (Second ed.) Philadelphia WB Saunders, 1994.
20. Kashinakunti SV, Kollur P, Kallaganada GS, Rangappa M, Ingin JB. Comparative study of serum MDA and vitamin C levels in non-smokers, chronic smokers and chronic smokers with acute myocardial infarction in men. J Res Med Sci. 2011; 16(8): 993-998.
21. Rahman T, Hosen I, Islam MMT, Shekhar HU. Oxidative stress and human health. Adv Biosci Biotechnol. 2012; 3: 997-1019. doi: 10. 4236/abb. 2012. 327123.
22. Kamble P, Trivdi DJ, Bargale A, Pandhare V, Zende P, Padalkar P. Role of xanthine oxidase, lipid peroxidation and uric acid in patients with acute myocardial infarction. Int J Pharm Biosci. 2011; 2(4): 395-399.
23. Holvoet P, Collen D. Oxidation of low density lipoproteins in the pathogenesis of atherosclerosis. Atherosclerosis. 1998; 137(Suppl): S33-S38.