Magnetic single-walled carbon nanotubes as efficient drug delivery nanocarriers in breast cancer murine model: Noninvasive monitoring using diffusion-weighted magnetic resonance imaging as sensitive imaging biomarker

International Journal of Nanomedicine

Volumn 10, Issue , 2014, Pages 157-168

  Al Faraj, Achraf ^a   Shaik, Abjal Pasha ^b   Shaik, Asma Sultana ^a  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Breast cancer; Carbon nanotubes; Diffusion weighted MRI; Drug delivery systems; Magnetic resonance imaging; Nanomedicine

Indexed keywords

ANTIBODY CONJUGATE; DOXORUBICIN; ENDOGLIN; MAGNETIC NANOPARTICLE; NANOCARRIER; SINGLE WALLED NANOTUBE; BIOLOGICAL MARKER; CARBON NANOTUBE; MAGNETITE NANOPARTICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BIOCOMPATIBILITY; BIOLUMINESCENCE; BREAST CANCER; CANCER GROWTH; CANCER LOCALIZATION; CONTROLLED STUDY; DIFFUSION WEIGHTED IMAGING; DNA DAMAGE; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SYNTHESIS; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NANOPROBE; NON INVASIVE MEASUREMENT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATIVE STRESS; TREATMENT RESPONSE; TUMOR CELL INOCULATION; ANIMAL; BAGG ALBINO MOUSE; BREAST NEOPLASMS; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; PROCEDURES; TUMOR CELL LINE;

MURINAE;

ANIMALS; APOPTOSIS; BIOMARKERS; BREAST NEOPLASMS; CELL LINE, TUMOR; DISEASE MODELS, ANIMAL; DNA DAMAGE; DOXORUBICIN; DRUG DELIVERY SYSTEMS; FEMALE; MAGNETIC RESONANCE IMAGING; MAGNETITE NANOPARTICLES; MICE; MICE, INBRED BALB C; NANOTUBES, CARBON;

EID: 84919783461     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S75074     Document Type: Article

References (25)

1. Jin S, Ye K. Targeted drug delivery for breast cancer treatment. Recent Pat Anticancer Drug Discov. 2013;8(2):143-153.
2. Sharma A, Jain N, Sareen R. Nanocarriers for diagnosis and targeting of breast cancer. Biomed Res Int. 2013;2013:960821.
3. Thakor AS, Gambhir SS. Nanooncology: the future of cancer diagnosis and therapy. CA Cancer J Clin. 2013;63(6):395-418.
4. Yang Z, Kang SG, Zhou R. Nanomedicine: de novo design of nanodrugs. Nanoscale. 2014;6(2):663-677.
5. Giles J. Top five in physics. Nature. 2006;441(7091):265.
6. Gong H, Peng R, Liu Z. Carbon nanotubes for biomedical imaging: the recent advances. Adv Drug Deliv Rev. 2013;65(15):1951-1963.
7. Vardharajula S, Ali SZ, Tiwari PM, et al. Functionalized carbon nanotubes: biomedical applications. Int J Nanomedicine. 2012;7:5361-5374.
8. Madani SY, Naderi N, Dissanayake O, Tan A, Seifalian AM. A new era of cancer treatment: carbon nanotubes as drug delivery tools. Int J Nanomedicine. 2011;6:2963-2979.
9. Kostarelos K, Bianco A, Prato M. Promises, facts and challenges for carbon nanotubes in imaging and therapeutics. Nat Nanotechnol. 2009;4(10):627-633.
10. Iyer AK, Khaled G, Fang J, Maeda H. Exploiting the enhanced permeability and retention effect for tumor targeting. Drug Discov Today. 2006;11(17-18):812-818.
11. Kostarelos K, Lacerda L, Pastorin G, et al. Cellular uptake of functionalized carbon nanotubes is independent of functional group and cell type. Nat Nanotechnol. 2007;2(2):108-113.
12. Lacerda L, Russier J, Pastorin G, et al. Translocation mechanisms of chemically functionalised carbon nanotubes across plasma membranes. Biomaterials. 2012;33(11):3334-3343.
13. Liu Z, Tabakman SM, Chen Z, Dai H. Preparation of carbon nanotube bioconjugates for biomedical applications. Nat Protoc. 2009;4(9):1372-1382.
14. Tacar O, Sriamornsak P, Dass CR. Doxorubicin: an update on anticancer molecular action, toxicity and novel drug delivery systems. J Pharm Pharmacol. 2013;65(2):157-170.
15. Al Faraj A, Sultana Shaik A, Al Sayed B. Preferential magnetic targeting of carbon nanotubes to cancer sites: noninvasive tracking using MRI in a murine breast cancer model. Nanomedicine. In press 2014.
16. Liu Z, Tabakman S, Welsher K, Dai H. Carbon nanotubes in biology and medicine: in vitro and in vivo detection, imaging and drug delivery. Nano Res. 2009;2(2):85-120.
17. Whisenant JG, Ayers GD, Loveless ME, Barnes SL, Colvin DC, Yankeelov TE. Assessing reproducibility of diffusion-weighted magnetic resonance imaging studies in a murine model of HER2+ breast cancer. Magn Reson Imaging. 2014;32(3):245-249.
18. Gu YJ, Cheng J, Jin J, Cheng SH, Wong WT. Development and evaluation of pH-responsive single-walled carbon nanotube-doxorubicin complexes in cancer cells. Int J Nanomedicine. 2011;6:2889-2898.
19. Al Faraj A, Shaik AS, Afzal S, Al Sayed B, Halwani R. MR imaging and targeting of a specific alveolar macrophage subpopulation in LPS-induced COPD animal model using antibody-conjugated magnetic nanoparticles. Int J Nanomedicine. 2014;9:1491-1503.
20. Yang S, Zhang JJ, Huang XY. Mouse models for tumor metastasis. Methods Mol Biol. 2012;928:221-228.
21. Liu Z, Fan AC, Rakhra K, et al. Supramolecular stacking of doxorubicin on carbon nanotubes for in vivo cancer therapy. Angew Chem Int Ed Engl. 2009;48(41):7668-7672.
22. Cai D, Mataraza JM, Qin ZH, et al. Highly efficient molecular delivery into mammalian cells using carbon nanotube spearing. Nat Methods. 2005;2(6):449-454.
23. Klumpp C, Kostarelos K, Prato M, Bianco A. Functionalized carbon nanotubes as emerging nanovectors for the delivery of therapeutics. Biochim Biophys Acta. 2006;1758(3):404-412.
24. Elhissi AM, Ahmed W, Hassan IU, Dhanak VR, D’Emanuele A. Carbon nanotubes in cancer therapy and drug delivery. J Drug Delivery. 2012;2012:837327.
25. Kim JB, Urban K, Cochran E, et al. Non-invasive detection of a small number of bioluminescent cancer cells in vivo. PLoS One. 2010;5(2):e9364.