Plant Lectins as Part of the Plant Defense System Against Insects

Induced Plant Resistance to Herbivory

Volumn , Issue , 2008, Pages 285-307

  Van Damme, Els J M ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84919779473     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4020-8182-8_14     Document Type: Chapter

References (130)

1. Agrawal AA (2003) Mechanisms, ecological consequences and agricultural implications of tritrophic interactions. Curr Opin Plant Biol 3:329-335
2. Bandyopadhyay S, Roy A, Das S (2001) Binding of garlic (Allium sativum) leaf lectin to the gut receptors of homopteran pests is correlated to its insecticidal activity. Plant Sci 161:1025-1033
3. Bano-Maqbool S, Riazuddin S, Loc NT, Gatehouse A M R., Gatehouse JA, Christou P (2001) Expression of multiple insecticidal genes confers broad resistance against a range of different rice pests. Mol Breed 7:85-93
4. Boulter D, Edwards GA, Gatehouse A M R, Gatehouse JA, Hilder VA (1990) Additive protective effects of different plant-derived insect resistance genes in transgenic tobacco plants. Crop Prot 9:351-354
5. Bourne Y, Astoul CH, Zamboni V, Peumans WJ, Menu-Bouaouiche L, Van Damme E J M, Barre A, Rougé P (2002) Structural basis for the unusual carbohydrate-binding specificity of jacalin towards galactose and mannose. Biochem J 364:173-180
6. Carlini CR, Grossi-de-Sà MF (2002) Plant toxic proteins with insecticidal properties. A review on their potentialities as bioinsecticides. Toxicon 40:1515-1539
7. Chang T, Chen L, Chen S, Cai H, Liu X, Xiao G, Zhu Z (2003) Transformation of tobacco with genes encoding Helianthus tuberosus agglutinin (HTA) confers resistance to peach-potato aphid (Myzus persicae). Transgenic Res 12:607-614
8. Chen Y, Peumans WJ, Hause B, Bras J, Kumar M, Proost P, Barre A, Rougé P, Van Damme E J M (2002) Jasmonic acid methyl ester induces the synthesis of a cytoplasmic/nuclear chitooligosaccharide-binding lectin in tobacco leaves. FASEB J 16:905-907
9. Christou P, Capell T, Kohli A, Gatehouse JA, Gatehouse A M R (2006) Recent developments and future prospects in insect pest control in transgenic crops. Trends Plant Sci 11:302-308
10. Claes B, Dekeyser R, Villarroel R, Van Den Bulcke M, Bauw G, Van Montagu M, Caplan A (1990) Characterization of a rice gene showing organ-specific expression in response to salt stress and drought. Plant Cell 2:19-27
11. Cristofoletti PT, De Sousa FA, Rahbé Y, Terra WR (2006) Characterization of a membrane-bound aminopeptidase purified from Acyrthosiphon pisum midgut cells. A major binding site for toxic mannose lectins. FEBS J 273:5574-5588
12. Czapla TH (1997) Plant lectins as insect control proteins in transgenic plants. In: Carozzi N, Koziel M (eds) Advances in insect control: the role of transgenic plants. Taylor and Francis, London, pp 123-138
13. Czapla TH, Lang BA (1990) Effect of plant lectins on the larval development of European corn borer (Lepidoptera: Pyralidae) and southern corn rootworm (Coleoptera: Chrysomelidae). J Econ Entomol 83:2480-2485
14. Down RE, Fitches EC, Wiles DP, Corti P, Bell HA, Gatehouse JA, Edwards JP (2006) Insecticidal spider venom toxin fused to snowdrop lectin is toxic to the peach-potato aphid, Myzus persicae (Hemiptera: Aphididae) and the rice brown planthopper, Nilaparvata lugens (Hemiptera: Delphacidae). Pest Manag Sci 62:77-85
15. Down RE, Gatehouse A M R, Hamilton WD, Gatehouse JA (1996) Snowdrop lectin inhibits development and decreases fecundity of the glasshouse potato aphid (Aulacorthum solani) when administered in vitro and via transgenic plants both in laboratory and glasshouse trials. J Insect Physiol 42:1035-1045
16. Du J, Foissac X, Carss A, Gatehouse A M R, Gatehouse JA (2000) Ferritin acts as the most abundant binding protein for snowdrop lectin in the midgut of rice brown planthoppers (Nilaparvata lugens). Insect Biochem Mol Biol 30:297-305
17. Dutta I, Majumder P, Saha P, Sakar A, Ray K, Das S (2005a) Constitutive and phloem specific expression of Allium sativum leaf agglutinin (ASAL) to engineer aphid (Lipaphis erysimi) resistance in transgenic Indian mustard (Brassica juncea). Plant Sci 169:996-1007
18. Dutta I, Saha P, Majumder, P, Sakar A, Chakraborti D, Banerjee S, Das S (2005b) The efficacy of a novel insecticidal protein, Allium sativum leaf lectin (ASAL), against homopteran insects monitored in transgenic tobacco. Plant Biotechnol J 3:601-611
19. Eisemann CH, Donaldson RA, Pearson RD, Cadogan LC, Vuocolo T, Tellam RL (1994) Larvicidal activity of lectins on Lucilia cuprina - Mechanism of action. Entomol Exp Appl 72:1-10
20. Fitches E, Audsley N, Gatehouse JA, Edwards JP (2002) Fusion proteins containing neuropeptides as novel insect contol agents: snowdrop lectin delivers fused allatostatin to insect haemolymph following oral ingestion. Insect Biochem Mol Biol 32:1653-1661
21. Fitches E, Edwards MG, Mee C, Grishin E, Gatehouse AM, Edwards JP, Gatehouse JA (2004) Fusion proteins containing insect-specific toxins as pest control agents: snowdrop lectin delivers fused insecticidal spider venom toxin to insect haemolymph following oral ingestion. J Insect Physiol 50:61-71
22. Fitches E, Gatehouse JA (1998) A comparison of the short and long term effects of insecticidal lectins on the activities of soluble and brush border enzymes of tomato moth larvae (Lacanobia oleracea). J Insect Physiol 44:1213-1224
23. Fitches E, Woodhouse SD, Edwards JP, Gatehouse, J. A. (2001) In vitro and in vivo binding of snowdrop (Galanthus nivalis agglutinin; GNA) and jack bean (Canavalia ensiformis; ConA) lectins within tomato moth (Lacanobia oleracea) larvae: mechanisms of insecticidal action. J Insect Physiol 47:777-787
24. Gatehouse A M R, Davison GM, Stewart JN, Gatehouse LN, Kumar A, Geoghegan IE, Birch A N E, Gatehouse JA (1999) Concanavalin A inhibits development of tomato moth (Lacanobia oleracea) and peach-potato aphid (Myzus persicae) when expressed in transgenic potato plants. Mol Breed 5:153-165
25. Gatehouse A M R, Davison GM, Newell CA, Merryweather A, Hamilton W D O, Burgess E P J, Gilbert R J C, Gatehouse JA (1997) Transgenic potato plants with enhanced resistance to the tomato moth, Lacanobia oleracea: growth room trials. Mol Breed 3:49-63
26. Gatehouse A M R, Howe DS, Flemming JE, Hilder VA, Gatehouse JA (1991) Biochemical basis of insect resistance in winged bean (Psophocarpus tetragonolobus) seeds. J Sci Food Agric 55:63-74
27. Gatehouse JA (2002) Plant resistance towards insect herbivores: a dynamic interaction. New Phytol 156:145-169
28. Gfeller A, Farmer EE (2004). Keeping the leaves green above us. Science 306:1515-1516
29. Giovanini MP, Saltmann KD, Puthoff DP, Gonzalo M, Ohm HW, Williams CE (2007) A novel wheat gene encoding a putative chitin-binding lectin is associated with resistance against Hessian fly. Mol Plant Pathol 8:69-82
30. Goldstein IJ, Poretz RD (1986) Isolation, physicochemical characterization, and carbohydratebinding specificity of lectins. In: Liener IE, Sharon N, Goldstein IJ (eds) The lectins, properties, functions, and applications in biology and medicine. Academic Press, Orlando, USA, pp 33-247
31. Guo HN, Jia YT, Zhou YG, Zhang ZS, Ouyang Q, Jiang Y, Tian YC (2004) Effects of transgenic tobacco plants expressing ACA gene from Amaranthus caudatus on the population development of Myzus persicae. Acta Bot Sin 46:1100-1105
32. Gupta GP, Birah A, Rani S (2005) Effect of plant lectins on growth and development of American bollworm (Helicoverpa armigera). Indian J Agric Sci 75:207-212
33. Habibi J, Backus EA, Czapla TH (1993) Plant lectins affect survival of the potato leafhopper (Homoptera: Cicadellidae). J Econ Entomol 86:945-951
34. Halitschke R, Baldwin IT (2004) Jasmonates and related compounds in plant-insect interactions. J Plant Growth Regul 23:238-245
35. Haq SK, Atif SM, Khan RH (2004) Protein proteinase inhibitor genes in combat against insects, pests, and pathogens: natural and engineered phytoprotection. Arch Biochem Biophys 431:145-159
36. Harper SM, Crenshaw RW, Mullins MA, Privalle LS (1995) Lectin binding to insect brush border membranes. J Econ Entomol 88:1197-1202
37. Harper MS, Hopkins TL, Czapla TH (1998) Effect of wheat germ agglutinin on formation and structure of the peritrophic membrane in European corn borer (Ostrinia nubilalis) larvae. Tissue Cell 30:166-176
38. Hilder VA, Powell KS, Gatehouse A M R, Gatehouse JA, Gatehouse LN, Shi Y, Hamilton W D O, Merryweather A, Newell C, Timans JC, Peumans WJ, Van Damme E J M, Boulter D (1995) Expression of snowdrop lectin in transgenic tobacco plants results in added protection against aphids. Transgenic Res 4:18-25
39. Huesing JE, Murdock LL, Shade RE (1991) Effect of wheat germ isolectins on development of cowpea weevil. Phytochemistry 30:785-788
40. Ishimoto M, Kitamura K (1989) Growth inhibitory effects of an a-amylase inhibitor from kidney bean, Phaseolus vulgaris (L.) on three species of bruchids (Coleoptera: Bruchidae). Appl Ent Zool 24:281-286
41. Ishimoto M, Sato T, Chrispeels MJ, Kitamura K (1996) Bruchid resistance of transgenic azuki bean expressing seed alpha-amylase inhibitor of common bean. Entomol Exp Appl 79:309-315
42. Kaku H, Van Damme E J M, Peumans WJ, Goldstein IJ (1990) Carbohydrate-binding specificity of the daffodil (Narcissus pseudonarcissus) and amaryllis (Hippeastrum hybr.) bulb lectins. Arch Biochem Biophys 279:298-304
43. Kaku H, Van Damme E J M, Peumans WJ, Goldstein IJ (1992) New mannose-specific lectins from garlic (Allium sativum) and ramsons (Allium ursinum) bulbs. Carbohydr Res 229:347-353
44. Kanrar S, Venkateswari J, Kirti PB, Chopra VL (2002) Transgenic Indian mustard (Brassica juncea) with resistance to the mustard aphid (Lipaphis erysimi Kalt). Plant Cell Rep 20:976-981
45. Kaur M, Singh K, Rup PJ, Kamboj SS, Saxena AK, Sharma M, Bhagat M, Sood SK, Singh J (2006) A tuber lectin from Arisaema jacquemontii Blume with anti-insect and anti-proliferative properties. J Biochem Mol Biol 39:432-440
46. Kessler A, Baldwin IT (2002). Plant responses to insect herbivory: the emerging molecular analysis. Ann Rev Plant Biol 53:299-328
47. Lannoo N, Peumans WJ, Van Pamel E, Alvarez R, Xiong TC, Hause G, Mazars C, Van Damme E J M (2006) Localization and in vitro binding studies suggest that the cytoplasmic/nuclear tobacco lectin can interact in situ with high-mannose and complex N-glycans. FEBS Lett 580:6329-6337
48. Larue-Achagiotis C, Picard M, Louis-Sylvestre J (1992) Feeding behavior in rats on a complete diet containing Concanavalin A. Reprod Nutr Dev 32:343-350
49. Lehane MJ (1997) Peritrophic membrane, structure and function. Ann Rev Entomol 42:525-550
50. Lord JM, Roberts LM, Robertus JD (1994) Ricin: structure, mode of action, and some current applications. FASEB J 8:201-208
51. Macedo M L R, Damico D C S, Freire MD, Toyama MH, Marangoni S, Novello JC (2003) Purification and characterization of an N-acetylglucosamine-binding lectin from Koelreuteria paniculata seeds and its effect on the larval development of Callosobruchus maculatus (Coleoptera: Bruchidae) and Anagasta kuehniella (Lepidoptera: Pyralidae). J Agric Food Chem 51:2980-2986
52. Macedo ML, Freire MD, Da Silva MB, Coelho LC (2006) Insecticidal action of Bauhinia monandra leaf lectin (BmoLL) against Anagasta kuehniella (Lepidoptera: Pyralidae), Zabrotes subfasciatus and Callosobruchus maculatus (Coleoptera: Bruchidae). Comp Biochem Physiol A Mol Integr Physiol 146:486-498
53. Majumder P, Banerjee S, Das S (2004) Identification of receptors responsible for binding of the mannose specific lectin to the gut epithelial membrane of the target insects. Glycoconj J 20:525-530
54. Majumder P, Mondal HA, Das S (2005) Insecticidal activity of Arum maculatum tuber lectin and its binding to the glycosylated insect gut receptors. J Agric Food Chem 53:6725-6729
55. Melander M, Ahman I, Kamnert I, Stromdahl AC (2003) Pea lectin expressed transgenically in oilseed rape reduces growth rate of pollen beetle larvae. Transgenic Res 12:555-567
56. Murdock LL, Huesing JE, Nielsen SS, Pratt RC, Shade RE (1990) Biological effects of plant lectins on the cowpea weevil. Phytochemistry 29:85-89
57. Murdock LL, Shade RE (2002) Lectins and protease inhibitors as plant defenses against insects. J Agric Food Chem 50:6605-6611
58. Musser RO, Hum-Musser SM, Eichenseer H, Peiffer M, Ervin G, Murphy JB, Felton GW (2002). Caterpillar salvia beats plant defenses. Nature 416:599-600
59. Neuteboom LW, Kunimitsu WY, Webb D, Christopher DA (2002) Characterization and tissueregulated expression of genes involved in pineapple (Ananas comosus L.) root development. Plant Sci 163:1021-1035
60. Noghabi SS, Van Damme E J M, Smagghe G (2006) Bioassays for insecticidal activity of iris ribosome-inactivating proteins expressed in tobacco plants. Commun Agric Appl Biol Sci 71:285-289
61. Okeola OG, Machuka J (2001) Biological effects of African yam bean lectins on Clavigralla tomentosicollis (Hemiptera: Coreidae). J Econ Entomol 94:724-729
62. Osborn TC, Alexander DC, Sun S S M, Cardona C, Bliss FA (1988) Insecticidal activity and lectin homology of arcelin seed protein. Science 240:207-210
63. Paes NS, Gerhardt IR, Coutinho MV, Yokoyama M, Santana E, Harris N, Chrispeels MJ, De Sa M F G (2000) The effect of arcelin-1 on the structure of the midgut of bruchid larvae and immunolocalization of the arcelin protein. J Insect Physiol 46:393-402
64. Parret AH, Schoofs G, Proost P, De Mot R (2003) Plant lectin-like bacteriocin from a rhizospherecolonizing Pseudomonas isolate. J Bacteriol 185:897-908
65. Parret AH, Temmerman K, De Mot R (2005) Novel lectin-like bacteriocins of biocontrol strain Pseudomonas fluorescens Pf-5. Appl Environ Microbiol 71:5197-5207
66. Peumans WJ, Barre A., Bras J, Rougé P, Proost P, Van Damme E J M (2002) The liverwort contains a lectin that is structurally and evolutionary related to the monocot mannose-binding lectins. Plant Physiol 129:1054-1065
67. Peumans WJ, Barre A, Hao Q, Rougé P, Van Damme E J M (2000) Higher plants developed structurally different motifs to recognize foreign glycans. Trends Glycosci Glycotechnol 12:83-101
68. Peumans WJ, Fouquaert E, Jauneau A, Rougé P, Lannoo N, Hamada H, Alvarez R, Devreese B, Van Damme E J M (2007) The liverwort Marchantia polymorpha expresses orthologs of the fungal Agaricus bisporus agglutinin family. Plant Physiol 144:637-647
69. Peumans WJ, Hao Q, Van Damme E J M (2001) Ribosome-inactivating proteins from plants: more than RNA N-glycosidases? FASEB J 15:1493-1506
70. Peumans WJ, Smeets K, Van Nerum K, Van Leuven F, Van Damme E J M. (1997) Lectin and alliinase are the predominant proteins in the nectar from leek (Allium porrum) flowers. Planta 201:298-302
71. Peumans WJ, Van Damme E J M (1995) Lectins as plant defense proteins. Plant Physiol 109:347-352
72. Peumans WJ, Van Damme E J M (1996) Prevalence, biological activity and genetic manipulation of lectins in foods. Trends Food Sci Technol 7:132-138
73. Pham Trung N, Fitches E, Gatehouse JA (2006) A fusion protein containing a lepidopteran-specific toxin from the South Indian red scorpion (Mesobuthus tamulus) and snowdrop lectin shows oral toxicity to target insects. BMC Biotechnol 6:34-42
74. Poulsen M, Kroghsbo S, Schroder M, Wilcks A, Jacobsen H, Miller A, Frenzel T, Danier J, Rychlik M, Shu Q, Emami K, Sudhakar D, Gatehouse A, Engel KH, Knudsen I (2007) A 90-day safety study in Wistar rats fed genetically modified rice expressing snowdrop lectin Galanthus nivalis (GNA). Food Chem Toxicol 45:350-363
75. Powell KS (2001) Antimetabolic effects of plant lectins towards nymphal stages of the planthoppers Tarophagous proserpina and Nilaparvata lugens. Entomol Exp Appl 99:71-77
76. Powell KS, Gatehouse A M R, Hilder VA, Gatehouse JA (1993) Antimetabolic effects of plant lectins and plant and fungal enzymes on the nymphal stages of two important rice pests, Nilaparvata lugens and Nephotettex cinciteps. Entomol Exp Appl 66:119-126
77. Powell KS, Gatehouse A M R, Hilder VA, Gatehouse JA (1995a) Antifeedant effects of plant lectins and an enzyme on the adult stage of the rice brown planthopper, Nilaparvata lugens. Entomol Exp Appl 75:51-59
78. Powell KS, Gatehouse A M R, Peumans WJ, Van Damme E J M, Boonjawat J, Horsham K, Gatehouse JA (1995b) Different antimetabolic effects of related plant lectins towards nymphal stages of Nilaparvata lugens. Entomol Exp Appl 75:61-65
79. Powell KS, Spance J, Bharathi M, Gatehouse JA, Gatehouse A M R (1998) Immnuohistochemical and development studies to elucidate the mechanism of action of the snowdrop lectin on the rice brown planthopper, Nilaparvata lugens (Stal). J Insect Physiol 67:529-539
80. Pusztai A, Ewen S W B, Grant G, Peumans WJ, Van Damme E J M, Rubio L, Bardocz S (1990) The relationship between survival and binding of plant lectins during small intestinal passage and their effectiveness as growth factors. Digestion 46:308-316
81. Puthoff DP, Sardesai N, Subramanyam S, Nemacheck JA, Williams CE (2005) Hfr-2, a wheat cytolytic toxin-like gene, is upregulated by virulent Hessian fly larval feeding. Mol Plant Pathol 6:41-423
82. Rahbe Y, Sauvion N, Febvay G, Peumans WJ, Gatehouse A M R (1995) Toxicity of lectins and processing of ingested proteins in the pea aphid Acyrthosiphon pisum. Entomol Exp Appl 76:143-155
83. Rao KV, Rathore KS, Hodges TK, Fu X, Stoger E, Sudhakar D, Williams S, Christou P, Bharathi M, Bown DP, Powell KS, Spence J, Gatehouse A M R, Gatehouse JA (1998) Expression of snowdrop lectin (GNA) in transgenic rice plants confers resistance to rice brown planthopper. Plant J 15:469-477
84. Reymond P, Bodenhausen N, Van Poecke RM, Krishnamurthy V, Dicke M, Farmer EE (2004) A conserved transcript pattern in response to a specialist and a generalist herbivore. Plant Cell 16:3132-3147
85. Rinderle SJ, Goldstein IJ, Matta KL, Ratcliffe RM (1989) Isolation and characterization of amaranthin, a lectin present in the seeds of Amaranthus caudatus, that recognizes the T-(or cryptic T)-antigen. J Biol Chem 264:16123-16131
86. Sabnis DD, Hart JW (1978) The isolation and some properties of a lectin (haemagglutinin) from Cucurbita phloem exudate. Planta 142:97-101
87. Sadeghi A, Smagghe G, Broeders S, Hernalsteens JP, De Greve H, Peumans WJ, Van Damme E J M (2008) Ectopically expressed leaf and bulb lectins from garlic (Allium sativum L.) protect transgenic tobacco plants against cotton leafworm (Spodoptera littoralis). Transgenic Res 17:9-18
88. Sadeghi A, Van Damme E J M, Peumans WJ, Smagghe G (2006) Deterrent activity of plant lectins on cowpea weevil Callosobruchus maculatus (F.) oviposition. Phytochemistry 67:2078-2084
89. Saha P, Majumder P, Dutta I, Ray T, Roy SC, Das S (2006) Transgenic rice expressing Allium sativum leaf lectin with enhanced resistance against sap-sucking insect pests. Planta 223:1329-1343
90. Sastry M V K, Banerjee P, Patanjali SR, Swamy MJ, Swarnalatha GV, Surolia A (1986) Analysis of the saccharide binding to Artocarpus integrifolia lectin reveals specific recognition of T-antigen β-D-Gal (1, 3) D-GalNAc). J Biol Chem 261:11726-11733
91. Sauvion N, Charles H, Febvay G, Rahbe Y (2004) Effects of jackbean lectin (ConA) on the feeding behaviour and kinetics of intoxication of the pea aphid, Acyrthosiphon pisum. Entomol Exp Appl 110:31-44
92. Sauvion N, Rahbe Y, Peumans WJ, Van Damme E J M, Gatehouse JA, Gatehouse A M R (1996) Effects of GNA and other mannose binding lectins on development and fecundity of the peach potato aphid Myzus persicae. Entomol Exp Appl 79:285-293
93. Setamou M, Bernal JS, Mirkov TE, Legaspi JC (2003) Effects of snowdrop lectin on Mexican rice borer (Lepidoptera: Pyralidae) life history parameters. J Econ Entomol 96:950-956
94. Shade RE, Schroeder HE, Pueyo JJ, Tabe LM, Murdock LL, Higgins T J V, Chrispeels MJ (1994) Transgenic pea seeds expressing the a-amylase inhibitor of the common bean are resistant to bruchid beetles. Biotechnology 12:793-796
95. Sharma HC, Sharma KK, Crouch JH (2004) Genetic transformation of crops for insect resistance: potential and limitations. Crit Rev Plant Sci 23:47-72
96. Sharma V, Surolia A (1997) Analyses of carbohydrate recognition by legume lectins: size of the combining site loops and their primary specificity. J Mol Biol 267:433-445
97. Shukla S, Arora R, Sharma HC (2005) Biological activity of soybean trypsin inhibitor and plant lectins against cotton bollworm/legume pod borer, Helicoverpa armigera. Plant Biotechnol 22:1-6
98. Singh T, Wu JH, Peumans WJ, Rougé P, Van Damme E J M, Alvarez RA, Blixt O, Wu AM (2006) Carbohydrate specificity of an insecticidal lectin isolated from the leaves of Glechoma hederacea (ground ivy) towards mammalian glycoconjugates. Biochem J 393:331-341
99. Stirpe F (2004) Ribosome-inactivating proteins. Toxicon 44:371-383
100. Stoger E, William S, Christou P, Down RE, Gatehouse JA (1999) Expression of the insecticidal lectin from snowdrop (Galanthus nivalis agglutinin; GNA) in transgenic wheat plants: effects on predation by the grain aphid Sitobion avenae. Mol Breed 5:65-73
101. Subramanyam S, Sardesai N, Puthoff DP, Meyer JM, Nemacheck JA, Gonzalo M, Williams CE (2006) Expression of two wheat defense-response genes, Hfr-1 and Wci-1, under biotic and abiotic stress. Plant Sci 170:90-103
102. Tsutsui S, Tasumi S, Suetake H, Suzuki Y (2003) Lectins homologous to those of monocotyledonous plants in the skin mucus and intestine of pufferfish, Fugu rubripes. J Biol Chem 278:20882-20889
103. Van Damme E J M, Allen AK, Peumans WJ (1987) Isolation and characterization of a lectin with exclusive specificity towards mannose from snowdrop (Galanthus nivalis) bulbs. FEBS Lett 215:140-144
104. Van Damme E J M, Barre A, Rougé P, Peumans WJ (2004). Cytoplasmic/nuclear plant lectins: a new story. Trends Plant Sci 9:484-489
105. Van Damme E J M, Barre A, Verhaert P, Rougé P, Peumans WJ (1996) Molecular cloning of the mitogenic mannose/maltose-specific rhizome lectin from Calystegia sepium. FEBS Lett 397:352-356
106. Van Damme E J M, Culerrier R, Barre A, Alvarez R, Rougé, P, Peumans WJ (2007a) A novel family of lectins evolutionarily related to class V chitinases: an example of neofunctionalization in legumes. Plant Physiol 144:662-672
107. Van Damme E J M, Hao Q, Chen Y, Barre A, Vandenbussche F, Desmyter S, Rougé P, Peumans WJ (2001) Ribosome-inactivating proteins: a family of plant proteins that do more than inactivate ribosomes. Crit Rev Plant Sci 20:395-465
108. Van Damme E J M, Peumans WJ, Barre A, Rougé P (1998a) Plant lectins: a composite of several distinct families of structurally and evolutionary related proteins with diverse biological roles. Crit Rev Plant Sci 17:575-692
109. Van Damme E J M, Peumans WJ, Pusztai A, Bardocz S (1998b) Handbook of plant lectins: properties and biomedical applications. John Wiley and Sons, Chichester, UK
110. Van Damme E J M, Rougé P, Peumans WJ (2007b) Carbohydrate-protein interactions: plant lectins. In: Kamerling JP, Boons GJ, Lee YC, Suzuki A, Taniguchi N, Voragen AGJ (eds) Comprehensive glycoscience - from chemistry to systems biology. Elsevier, Oxford, UK, vol 3, pp 563-599
111. Van Damme E J M, Smeets K, Engelborghs I, Aelbers H, Balzarini J, Pusztai A, Van Leuven F, Goldstein IJ, Peumans WJ (1993) Cloning and characterization of the lectin cDNA clones from onion, shallot and leek. Plant Mol Biol 23:365-376
112. Vandenbussche F, Desmyter S, Ciani M, Proost P, Peumans WJ, Van Damme E J M (2004a) Analysis of the in planta antiviral activity of elderberry ribosome-inactivating proteins. Eur J Biochem 271:1508-1515
113. Vandenbussche F, Peumans WJ, Desmyter S, Proost, P, Ciani M, Van Damme E J M (2004b) The type-1 and type-2 ribosome-inactivating proteins from Iris confer transgenic tobacco plants local but not systemic protection against viruses. Planta 220:211-221
114. Waljuno K, Scholma RA, Beintema J, Mariono A, Hahn AM (1975) Amino acid sequence of hevein. In: Proceedings of the International Rubber Conference, Kuala Lumpur, vol 2. Rubber Research Institute of Malaysia, Kuala Lumpur, pp 518-531
115. Wang P, Li G, Granados RR (2004). Identification of two new peritrophic membrane proteins from larval Trichoplusia ni: structural characteristics and their functions in the protease rich insect gut. Insect Biochem Mol Biol 34:215-227
116. Wang W, Hause B, Peumans WJ, Smagghe G, Mackie A, Fraser R, Van Damme E J M (2003b) The Tn antigen-specific lectin from ground ivy is an insecticidal protein with an unusual physiology. Plant Physiol 132:1322-1334
117. Wang W, Peumans WJ, Rougé P, Rossi C, Proost P, Chen J, Van Damme E J M (2003a) Leaves of the Lamiaceae species Glechoma hederacea (ground ivy) contain a lectin that is structurally and evolutionary related to the legume lectins. Plant J 33:293-304
118. Wei GQ, Liu RS, Wang Q, Liu WY (2004) Toxicity of two type II ribosome-inactivating proteins (cinnamomin and ricin) to domestic silkworm larvae. Arch Insect Biochem Physiol 57:160-165
119. Williams CE, Collier CC, Nemacheck JA, Liang C, Cambron SE (2002) A lectin-like wheat gene responds systemically to attempted feeding by avirulent first-instar Hessian fly larvae. J Chem Ecol 28:1411-1428
120. Wu AM (2005) Lectinochemical studies on the glyco-recognition factors of a Tn (a->Ser/Thr) specific lectin isolated from the seeds of Salvia sclarea. J Biomed Sci 12:167-184
121. Wu J, Luo X, Guo H, Xiao J, Tian Y (2006) Transgenic cotton, expressing Amaranthus caudatus agglutinin, confers enhanced resistance to aphids. Plant Breed 125:390-394
122. Yagi F, Hidaka M, Minami Y, Tadera K (1996) A lectin from leaves of Neoregelia flandria recognizes D-glucose, D-mannose and N-acetylglucosamine, differing from the mannose-specific lectins from other monocotyledonous species. Plant Cell Physiol 37:1007-1012
123. Yao J, Pang Y, Qi H, Wan B, Zhao X, Kong W, Sun X, Tang K (2003) Transgenic tobacco expressing Pinellia ternata agglutinin confers enhanced resistance to aphids. Transgenic Res 12:715-722
124. Young NM, Oomen RP (1992) Analysis of sequence variation among legume lectins. A ring of hypervariable residues forms the perimeter of the carbohydrate-binding site. J Mol Biol 228:924-934
125. Zhang W, Peumans WJ, Barre A, Houles-Astoul C, Rovira P, Rougé P, Proost P, Truffa-Bachi P, Jalali A A H, Van Damme E J M (2000) Isolation and characterization of a jacalin-related mannose-binding lectin from salt-stressed rice (Oryza sativa) plants. Planta 210:970-978
126. Zhou X, Li XD, Yuan JZ, Tang ZH, Liu WY (2000) Toxicity of cinnamomin - a new type II ribosome-inactivating protein to bollworm and mosquito. Insect Biochem Mol Biol 30:259-264
127. Zhu K, Huesing JE, Shade RE, Bressan RA, Hasegawa PM, Murdock LL (1996) An insecticidal N-acetylglucosamine-specific lectin gene from Griffonia simplicifolia (Leguminosae). Plant Physiol 110:195-202
128. Zhu-Salzman K, Salzman RA (2001) Functional mechanics of the plant defensive Griffonia simplicifolia lectin II: resistance to proteolysis is independent of glycoconjugate binding in the insect gut. J Econ Entomol 94:1280-1284
129. Zhu-Salzman K, Salzman RA, Koiwa H, Murdock LL, Bressan RA, Hasegawa PM (1998) Ethylene negatively regulates local expression of plant defense lectin genes. Physiol Plant 104:365-372
130. Zhu-Salzman K, Shade RE, Koiwa H, Salzman RA, Narasimhan M, Bressam RA, Hasegawa PM, Murdock LL (1996) Carbohydrate binding and resistance to proteolysis control insecticidal activity of Griffonia simplicifolia lectin II. Proc Natl Acad Sci USA 95:15123-15128