Toll-like receptor 4 inhibition reduces vascular inflammation in spontaneously hypertensive rats

Life Sciences

Volumn 122, Issue , 2015, Pages 1-7

  Bomfim, G F ^a,b   Echem, C ^b   Martins, C B ^b   Costa, T J ^b   Sartoretto, S M ^b   Dos Santos, R A ^b   Oliveira, M A ^b   Akamine, E H ^b   Fortes, Z B ^b   Tostes, R C ^b   Webb, R C ^c   Carvalho, M H C ^b  

^a FEDERAL UNIVERSITY OF MATO GROSSO   (Brazil)

^b UNIVERSITY OF SÃO PAULO   (Brazil)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Hypertension; Innate immune response; NF B; Toll like receptor

Indexed keywords

IMMUNOGLOBULIN G; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOID DIFFERENTIATION FACTOR 88; NORADRENALIN; REACTIVE OXYGEN METABOLITE; RECEPTOR ANTIBODY; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 4 ANTIBODY; TOLL LIKE RECEPTOR AFFECTING AGENT; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; MONOCLONAL ANTIBODY; TLR4 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTERY CONSTRICTION; ARTICLE; BLOOD VESSEL REACTIVITY; BODY WEIGHT; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HYPERTENSION; INNATE IMMUNITY; MALE; MEAN ARTERIAL PRESSURE; MESENTERIC ARTERY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RESISTANCE BLOOD VESSEL; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; VASCULITIS; WISTAR RAT; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD PRESSURE; CELL CULTURE; DRUG EFFECTS; IMMUNOLOGY; INFLAMMATION; METABOLISM; PHOSPHORYLATION; WESTERN BLOTTING;

RATTUS; RATTUS NORVEGICUS;

ANIMALS; ANTIBODIES, MONOCLONAL; BLOOD PRESSURE; BLOTTING, WESTERN; CELLS, CULTURED; CYTOKINES; HYPERTENSION; INFLAMMATION; MALE; MESENTERIC ARTERIES; PHOSPHORYLATION; RATS; RATS, INBRED SHR; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4;

EID: 84919779360     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2014.12.001     Document Type: Article

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