Particle size effects on protein and virus-like particle adsorption on perfusion chromatography media

Journal of Chromatography A

Volumn 1375, Issue , 2015, Pages 92-100

  Wu, Yige ^a   Abraham, Dicky ^b   Carta, Giorgio ^a  

^a University of Virginia   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Mass transfer; Perfusion chromatography; Proteins; Virus like particles

Indexed keywords

ADSORPTION; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; HYDRAULIC STRUCTURES; MASS TRANSFER; PARTICLE SIZE; PROTEINS; RESINS; VIRUSES;

CONFOCAL LASER SCANNING MICROSCOPY; EFFECTIVE DIFFUSIVITIES; HEIGHT EQUIVALENT TO A THEORETICAL PLATES; INVERSE SIZE EXCLUSION CHROMATOGRAPHY; PARTICLE SIZE EFFECT; PERFUSION CHROMATOGRAPHY; PREDICTIVE ABILITIES; VIRUS-LIKE PARTICLES;

SIZE EXCLUSION CHROMATOGRAPHY;

IMMUNOGLOBULIN G; PROTEIN; RESIN; CAPSID PROTEIN; CATION EXCHANGE RESIN;

ADSORPTION; ARTICLE; CHROMATOGRAPHY; CONFOCAL LASER MICROSCOPY; DIFFUSION; FLOW RATE; GEL PERMEATION CHROMATOGRAPHY; PARTICLE SIZE; PERFUSION CHROMATOGRAPHY; TRANSMISSION ELECTRON MICROSCOPY; VIRUS LIKE AGENT; CHEMISTRY; KINETICS;

ADSORPTION; CAPSID PROTEINS; CATION EXCHANGE RESINS; CHROMATOGRAPHY; KINETICS; PARTICLE SIZE; PROTEINS;

EID: 84919682073     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.11.083     Document Type: Article

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