A computational study of stimulus driven epileptic seizure abatement

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Taylor, Peter Neal ^a   Wang, Yujiang ^a   Marc, Goodfellow ^b   Justin, Dauwels ^c   Friederike, Moeller ^d   Ulrich, Stephani ^d   Gerold, Baier ^e  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF EXETER   (United Kingdom)

^c NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

^d UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CONTROLLED STUDY; MATHEMATICAL ANALYSIS; NEURAL POPULATION MODEL; NOISE REDUCTION; PHYSICAL MODEL; PROBABILITY; SEIZURE; SIMULATION; SPIKE WAVE; THALAMOCORTICAL TRACT; ANIMAL; BIOLOGICAL MODEL; BRAIN; ELECTROSTIMULATION THERAPY; EPILEPSY; HUMAN; PATHOPHYSIOLOGY; RAT;

ANIMALS; BRAIN; ELECTRIC STIMULATION THERAPY; EPILEPSY; HUMANS; MODELS, NEUROLOGICAL; PROBABILITY; RATS;

EID: 84919667672     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114316     Document Type: Article

References (51)

1. Caplan R, Siddarth P, Stahl L, Lanphier E, Vona P, et al. (2008) Childhood absence epilepsy: behavioral, cognitive, and linguistic comorbidities. Epilepsia 49: 1838-46.
2. Barnes GN, Paolicchi JM (2008) Neuropsychiatric comorbidities in childhood absence epilepsy. Nat Clin Pract Neurol 4: 650-1.
3. Selai C, Bannister D, Trimble M (2005) Antiepileptic drugs and the regulation of mood and quality of life (QOL): the evidence from epilepsy. Epilepsia 46: 50-57.
4. Al-Otaibi FA, Hamani C, Lozano AM (2011) Neuromodulation in epilepsy. Neurosurgery 69: 957-979.
5. Beré nyi A, Belluscio M, Mao D, Buzsáki G (2012) Closed-loop control of epilepsy by transcranial electrical stimulation. Science 337: 735-737.
6. Saillet S, Gharbi S, Charvet G, Deransart C, Guillemaud R, et al. (2013) Neural adaptation to responsive stimulation: A comparison of auditory and deep brain stimulation in a rat model of absence epilepsy. Brain Stimul 6:3: 241-247.
7. Dedeurwaerdere S, Vonck K, Claeys P, Van Hese P, D Havé M, et al. (2004) Acute vagus nerve stimulation does not suppress spike and wave discharges in genetic absence epilepsy rats from strasbourg. Epilepsy Res 59: 191-198.
8. Rajna P, Lona C (1989) Sensory stimulation for inhibition of epileptic seizures. Epilepsia 30: 168-174.
9. Conte A, Gilio F, Iacovelli E, Bettolo C, Di Bonaventura C, et al. (2007) Effects of repetitive transcranial magnetic stimulation on spike-and-wave discharges. Neurosci Res 57: 140-142.
10. Anderson W, Kudela P, Cho J, Bergey G, Franaszczuk P (2007) Studies of stimulus parameters for seizure disruption using neural network simulations. Biol Cybern 97: 173-194.
11. Robinson PA, Rennie CJ, Rowe DL (2002) Dynamics of large-scale brain activity in normal arousal states and epileptic seizures. Phys Rev E 65: 041924.
12. Breakspear M, Roberts J, Terry J, Rodrigues S, Mahant N, et al. (2006) A unifying explanation of primary generalized seizures through nonlinear brain modeling and bifurcation analysis. Cereb Cortex 16: 1296-1313.
13. Goodfellow M, Schindler K, Baier G (2011) Intermittent spike-wave dynamics in a heterogeneous, spatially extended neural mass model. NeuroImage 55: 920-932.
14. Taylor P, Baier G (2011) A spatially extended model for macroscopic spike-wave discharges. J Comput Neurosci 31: 679-684.
15. Wang Y, Goodfellow M, Taylor P, Baier G (2012) Phase space approach for modeling of epileptic dynamics. Phys Rev E 85: 061918.
16. Pinault D, O'Brien T (2005) Cellular and network mechanisms of genetically-determined absence seizures. Thalamus Relat Syst 3: 181-203.
17. Meeren H, van Luijtelaar G, Lopes da Silva F, Coenen A (2005) Evolving concepts on the pathophysiology of absence seizures: the cortical focus theory. Arch Neurol 62: 371-376.
18. Moeller F, Siebner H, Wolff S, Muhle H, Granert O, et al. (2008) Simultaneous EEG-fMRI in drug-naive children with newly diagnosed absence epilepsy. Epilepsia 49: 1510-1519.
19. Moeller F, LeVan P, Muhle H, Stephani U, Dubeau F, et al. (2010) Absence seizures: Individual patterns revealed by EEG-fMRI. Epilepsia 51: 2000-2010.
20. Moeller F, Muthuraman M, Stephani U, Deuschl G, Raethjen J, et al. (2013) Representation and propagation of epileptic activity in absences and generalized photoparoxysmal responses. Human brain mapping 34: 1896-1909.
21. Lopes Da Silva F, Blanes W, Kalitzin S, Parra J, Suffczynski P, et al. (2003) Epilepsies as dynamical diseases of brain systems: basic models of the transition between normal and epileptic activity. Epilepsia 44: 72-83.
22. Suffczynski P, Kalitzin S, Lopes Da Silva F (2004) Dynamics of non-convulsive epileptic phenomena modeled by a bistable neuronal network. Neuroscience 126: 467-484.
23. Suffczynski P, da Silva F, Parra J, Velis D, Bouwman B, et al. (2006) Dynamics of epileptic phenomena determined from statistics of ictal transitions. IEEE T Biomed-Eng 53: 524-532.
24. Foss J, Milton J (2003) Aborting seizures with a single stimulus: The case for multistability. In, : Milton J, Jung P, editors, Epilepsy as a dynamic disease, Springer. pp. 283-295.
25. McCormick DA, Contreras D (2001) On the cellular and network bases of epileptic seizures. Annu Rev Physiol 63: 815-46.
26. Theiler J (1994) On the evidence for low-dimensional chaos in an epileptic electroencephalogram. Phys Lett A 196: 335-341.
27. Milton J, Black D (1995) Dynamic diseases in neurology and psychiatry. Chaos 5: 8-13.
28. Fro? hlich F, Sejnowski TJ, Bazhenov M (2010) Network bistability mediates spontaneous transitions between normal and pathological brain states. J Neurosci 30: 10734-10743.
29. Osorio I, Frei M (2009) Seizure abatement with single dc pulses: is phase resetting at play? Int J Neural Syst 19: 149-156.
30. Motamedi GK, Lesser RP, Miglioretti DL, Mizuno-Matsumoto Y, Gordon B, et al. (2002) Optimizing parameters for terminating cortical afterdischarges with pulse stimulation. Epilepsia 43: 1441-1441.
31. Cagnan H, Brittain JS, Little S, Foltynie T, Limousin P, et al. (2013) Phase dependent modulation of tremor amplitude in essential tremor through thalamic stimulation. Brain 136: 3062-75.
32. Meeren H, Pijn J, Van Luijtelaar E, Coenen A, Lopes da Silva F (2002) Cortical focus drives widespread corticothalamic networks during spontaneous absence seizures in rats. The Journal of Neuroscience 22: 1480.
33. Paz JT, Davidson TJ, Frechette ES, Delord B, Parada I, et al. (2013) Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury. Nat Neurosci 16: 64-70.
34. Kramer MA, Lopour BA, Kirsch HE, Szeri AJ (2006) Bifurcation control of a seizing human cortex. Phys Rev E 73: 041928.
35. Chakravarthy N, Tsakalis K, Sabesan S, Iasemidis L (2009) Homeostasis of brain dynamics in epilepsy: a feedback control systems perspective of seizures. Ann Biomed Eng 37: 565-585.
36. Destexhe A (1998) Spike-and-wave oscillations based on the properties of GABAB receptors. J Neurosci 18: 90-99.
37. Rodrigues S, Terry JR, Breakspear M (2006) On the genesis of spike-wave oscillations in a mean-field model of human thalamic and corticothalamic dynamics. Phys Lett A 355: 352-357.
38. Terry JR, Benjamin O, Richardson MP (2012) Seizure generation: The role of nodes and networks. Epilepsia 53: e166-e169.
39. Taylor PN, Baier G, Cash SS, Dauwels J, Slotine JJ, et al. (2013) A model of stimulus induced epileptic spike-wave discharges. IEEE Proc SSCI 2013: 53-59.
40. Taylor P, Goodfellow M, Wang Y, Baier G (2013) Towards a large-scale model of patient-specific epileptic spike-wave discharges. Biol Cybern 107: 83-94.
41. Taylor PN, Kaiser M, J D (2014) Structural connectivity based whole brain modelling in epilepsy. J Neurosci Meth 236: 51-57.
42. Sinha N, Taylor P, Dauwels J, Ruths J (2014) Development of optimal stimuli in a heterogeneous model of epileptic spike-wave oscillations. Proceedings IEEE SMC.
43. Avoli M (2012) A brief history on the oscillating roles of thalamus and cortex in absence seizures. Epilepsia 53: 779-789.
44. Amari S (1977) Dynamics of pattern formation in lateral-inhibition type neural fields. Biol Cybern 27: 77-87.
45. Yousif N, Denham M (2005) A population-based model of the nonlinear dynamics of the thalamocortical feedback network displays intrinsic oscillations in the spindling (7-14 hz) range. Eur J Neurosci 22: 3179-3187.
46. Steriade M, Contreras D (1998) Spike-wave complexes and fast components of cortically generated seizures. i. role of neocortex and thalamus. J Neurophysiol 80: 1439-1455.
47. Cope DW, Di Giovanni G, Fyson SJ, Orbán G, Errington AC, et al. (2009) Enhanced tonic GABAA inhibition in typical absence epilepsy. Nat Med 15: 1392-1398.
48. Marten F, Rodrigues S, Suffczynski P, Richardson M, Terry J (2009) Derivation and analysis of an ordinary differential equation mean-field model for studying clinically recorded epilepsy dynamics. Phys Rev E 79: 021911.
49. Fenichel N (1979) Geometric singular perturbation theory for ordinary differential equations. J Differ Equations 31: 53-98.
50. Takens F (1981) Detecting strange attractors in turbulence. In, : Dynamical systems and turbulence, Springer. pp. 366-381.
51. Oprisan S, Thirumalai V, Canavier CC (2003) Dynamics from a time series: can we extract the phase resetting curve from a time series? Biophys J 84: 2919-2928.