Cargoing P-gp inhibitors via nanoparticle sensitizes tumor cells against doxorubicin

International Journal of Pharmaceutics

Volumn 478, Issue 2, 2015, Pages 745-752

  Singh, Manu Smriti ^a   Lamprecht, Alf ^a,b  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITÉ DE FRANCHE COMTÉ   (France)

Author keywords

Cancer; Inhibitor; Multidrug resistance; Nanoparticle; P gp

Indexed keywords

CATIONIC SURFACTANT; DOXORUBICIN; ELACRIDAR; GLYCOPROTEIN P INHIBITOR; MULTIDRUG RESISTANCE PROTEIN; NANOCARRIER; RHODAMINE 123; VERAPAMIL; ACRIDINE DERIVATIVE; ANTINEOPLASTIC ANTIBIOTIC; DODECYL SULFATE SODIUM; DRUG CARRIER; NANOPARTICLE; POLYVINYL ALCOHOL; SURFACTANT; TETRAHYDROISOQUINOLINE DERIVATIVE;

ARTICLE; CHEMOSENSITIZATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG FORMULATION; ENDOCYTOSIS; FEMALE; HUMAN; HUMAN CELL; HYDROPHILICITY; IC50; IN VITRO STUDY; INTERNALIZATION; LIPOPHILICITY; MULTIDRUG RESISTANCE; NANOENCAPSULATION; OVARIAN CANCER CELL LINE; SURFACE CHARGE; SUSTAINED DRUG RELEASE; ZETA POTENTIAL; ANTAGONISTS AND INHIBITORS; CELL SURVIVAL; CHEMISTRY; DRUG RESISTANCE; METABOLISM; NEOPLASM; TUMOR CELL LINE;

ACRIDINES; ANTIBIOTICS, ANTINEOPLASTIC; CELL LINE, TUMOR; CELL SURVIVAL; DOXORUBICIN; DRUG CARRIERS; DRUG RESISTANCE, NEOPLASM; HUMANS; NANOPARTICLES; NEOPLASMS; P-GLYCOPROTEIN; POLYVINYL ALCOHOL; SODIUM DODECYL SULFATE; SURFACE-ACTIVE AGENTS; TETRAHYDROISOQUINOLINES; VERAPAMIL;

EID: 84919626504     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.11.064     Document Type: Article

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