Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 46, 2014, Pages 16478-16483

  Fredericks, Gregory J ^a   Hoffmann, FuKun W ^a   Rose, Aaron H ^a   Osterheld, Hanna J ^b   Hess, Franz M ^a   Mercier, Frederic ^a   Hoffmann, Peter R ^a  

^a UNIVERSITY OF HAWAII   (United States)

^b MANNHEIM UNIVERSITY OF APPLIED SCIENCES   (Germany)

Author keywords

Calcium; Endoplasmic reticulum; Immune; Palmitoylation; Selenium

Indexed keywords

ASPARTIC ACID; CYSTEINE; HISTIDINE; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; PROTEIN SH3; SELENIUM; SELENOPROTEIN; SELENOPROTEIN K COMPLEX; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; ACYLTRANSFERASE; HYBRID PROTEIN; ITPR1 PROTEIN, HUMAN; ITPR1 PROTEIN, MOUSE; ITPR1 PROTEIN, RAT; MULTIPROTEIN COMPLEX; SELENOPROTEIN K, MOUSE; SMALL INTERFERING RNA; THAPSIGARGIN; ZDHHC6 PROTEIN, HUMAN; ZDHHC6 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOINFORMATICS; CALCIUM TRANSPORT; CONTROLLED STUDY; CULTURE MEDIUM; ENDOPLASMIC RETICULUM MEMBRANE; GENE DELETION; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; JURKAT CELL LINE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PALMITOYLATION; PROTEIN FUNCTION; STABLE EXPRESSION; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE MARROW CELL; CALCIUM SIGNALING; CHEMISTRY; DEFICIENCY; DRUG EFFECTS; ENDOPLASMIC RETICULUM; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; HUMAN; KNOCKOUT MOUSE; LIPOYLATION; METABOLISM; PHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN PROCESSING; RAT; SITE DIRECTED MUTAGENESIS; SRC HOMOLOGY DOMAIN; T LYMPHOCYTE SUBPOPULATION;

ACYLTRANSFERASES; ANIMALS; BONE MARROW CELLS; CALCIUM SIGNALING; CYSTEINE; ENDOPLASMIC RETICULUM; HEK293 CELLS; HUMANS; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; JURKAT CELLS; LIPOYLATION; MICE; MICE, KNOCKOUT; MULTIPROTEIN COMPLEXES; MUTAGENESIS, SITE-DIRECTED; PROTEIN INTERACTION MAPPING; PROTEIN PROCESSING, POST-TRANSLATIONAL; RATS; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING; SELENIUM; SELENOPROTEINS; SRC HOMOLOGY DOMAINS; T-LYMPHOCYTE SUBSETS; THAPSIGARGIN; TRANSFECTION;

EID: 84919487651     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1417176111     Document Type: Article

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