A negatively charged residue stabilizes the tropoelastin N-terminal region for elastic fiber assembly

Journal of Biological Chemistry

Volumn 289, Issue 50, 2014, Pages 34815-34826

  Yeo, Giselle C ^a   Baldock, Clair ^b   Wise, Steven G ^c,d   Weiss, Anthony S ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c HEART RESEARCH INSTITUTE   (Australia)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ASSOCIATION REACTIONS; CELL CULTURE; ELASTICITY;

ASPARTATE RESIDUE; CONFORMATIONAL CHANGE; EXTRACELLULAR MATRIX PROTEIN; HUMAN DERMAL FIBROBLASTS; NEGATIVELY CHARGED; POSITIVELY CHARGED; SELF-ASSOCIATIONS; SWELLING PROPERTIES;

FIBERS;

ALANINE; ASPARTIC ACID; MUTANT PROTEIN; SCLEROPROTEIN; TROPOELASTIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ELASTIC FIBER; ELASTICITY; HUMAN; HUMAN CELL; HYDROGEL; MUTATION; NUCLEOTIDE SEQUENCE; PIGMENT EPITHELIUM; PROTEIN ASSEMBLY; PROTEIN CROSS LINKING; PROTEIN FUNCTION; SKIN FIBROBLAST; STRENGTH; SURFACE CHARGE; CHEMICAL STRUCTURE; CHEMISTRY; CYTOLOGY; FIBROBLAST; GENETICS; METABOLISM; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS; SKIN;

VERTEBRATA;

ASPARTIC ACID; ELASTICITY; FIBROBLASTS; HUMANS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN STABILITY; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SKIN; TROPOELASTIN;

EID: 84919459895     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.606772     Document Type: Article

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