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Volumn 33, Issue 2, 2015, Pages 639-650

The indicative function of Twist2 and E-cadherin in HPV oncogene-induced epithelial-mesenchymal transition of cervical cancer cells

Author keywords

Cervical cancer; E cadherin; Epithelial mesenchymal transition; Human papillomavirus 16; Twist2

Indexed keywords

PROTEIN E2; PROTEIN E6; PROTEIN E7; TRANSCRIPTION FACTOR TWIST; TRANSCRIPTION FACTOR TWIST2; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; VIRUS PROTEIN; CADHERIN; REPRESSOR PROTEIN; TWIST2 PROTEIN, HUMAN; VIRUS ANTIGEN;

EID: 84919458936     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3620     Document Type: Article
Times cited : (16)

References (42)
  • 1
    • 0036559896 scopus 로고    scopus 로고
    • Papillomaviruses and cancer: From basic studies to clinical application
    • Zur Hausen H: Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer 2: 342-350, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 342-350
    • Zur Hausen, H.1
  • 2
    • 79957801393 scopus 로고    scopus 로고
    • Oncogenic potential of human papillomavirus (HPV) and its relation with cervical cancer
    • Faridi R, Zahra A, Khan K and Idrees M: Oncogenic potential of human papillomavirus (HPV) and its relation with cervical cancer. Virol J 8: 269, 2011.
    • (2011) Virol J , vol.8 , pp. 269
    • Faridi, R.1    Zahra, A.2    Khan, K.3    Idrees, M.4
  • 3
    • 58849113924 scopus 로고    scopus 로고
    • Etiology and pathoGenesis of precancerous lesions and invasive cervical carcinoma
    • (In Serbian)
    • Panjkovic M and Ivkovic-Kapicl T: Etiology and pathoGenesis of precancerous lesions and invasive cervical carcinoma. Med Pregl 61: 364-368, 2008 (In Serbian).
    • (2008) Med Pregl , vol.61 , pp. 364-368
    • Panjkovic, M.1    Ivkovic-Kapicl, T.2
  • 4
    • 31144456195 scopus 로고    scopus 로고
    • HPV-mediated cervical carcinoGenesis: Concepts and clinical implications
    • Snijders PJ, Steenbergen RD, Heideman DA and Meijer CJ: HPV-mediated cervical carcinoGenesis: concepts and clinical implications. J Pathol 208: 152-164, 2006.
    • (2006) J Pathol , vol.208 , pp. 152-164
    • Snijders, P.J.1    Steenbergen, R.D.2    Heideman, D.A.3    Meijer, C.J.4
  • 5
    • 84870741214 scopus 로고    scopus 로고
    • Uterine cervix carcinoma: Recent biological data and update for improving follow-up and treatment
    • Javier MG and Sastre-Garau X: uterine cervix carcinoma: recent biological data and update for improving follow-up and treatment. Isr Med Assoc J 14: 700-704, 2012.
    • (2012) Isr Med Assoc J , vol.14 , pp. 700-704
    • Javier, M.G.1    Sastre-Garau, X.2
  • 6
    • 77149149956 scopus 로고    scopus 로고
    • The biological properties of E6 and E7 oncop-roteins from human papillomaviruses
    • Ghittoni R, Accardi R, Hasan U, Gheit T, Sylla B and Tommasino M: The biological properties of E6 and E7 oncop-roteins from human papillomaviruses. Virus Genes 40: 1-13, 2010.
    • (2010) Virus Genes , vol.40 , pp. 1-13
    • Ghittoni, R.1    Accardi, R.2    Hasan, U.3    Gheit, T.4    Sylla, B.5    Tommasino, M.6
  • 7
    • 84873050284 scopus 로고    scopus 로고
    • Regulatory networks defning EMT during cancer initiation and progression
    • De Craene B and Berx G: Regulatory networks defning EMT during cancer initiation and progression. Nat Rev Cancer 13: 97-110, 2013.
    • (2013) Nat Rev Cancer , vol.13 , pp. 97-110
    • De Craene, B.1    Berx, G.2
  • 8
    • 84871171526 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in carcinomas of the female genital tract
    • Stewart CJ and McCluggage WG: Epithelial-mesenchymal transition in carcinomas of the female genital tract. Histopathology 62: 31-43, 2013.
    • (2013) Histopathology , vol.62 , pp. 31-43
    • Stewart, C.J.1    McCluggage, W.G.2
  • 9
    • 84865839326 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions: Insights from development
    • Lim J and Thiery JP: Epithelial-mesenchymal transitions: insights from development. Development 139: 3471-3486, 2012.
    • (2012) Development , vol.139 , pp. 3471-3486
    • Lim, J.1    Thiery, J.P.2
  • 10
    • 84867251505 scopus 로고    scopus 로고
    • The regulation of cell-cell adhesion during epithelial-mesenchymal transition, motility and tumor progression
    • Le Bras GF, Taubenslag KJ and Andl CD: The regulation of cell-cell adhesion during epithelial-mesenchymal transition, motility and tumor progression. Cell Adh Migr 6: 365-373, 2012.
    • (2012) Cell Adh Migr , vol.6 , pp. 365-373
    • Le Bras, G.F.1    Taubenslag, K.J.2    Andl, C.D.3
  • 12
    • 75649151387 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer development and its clinical signifcance
    • Iwatsuki M, Mimori K, Yokobori T, et al: Epithelial-mesenchymal transition in cancer development and its clinical signifcance. Cancer Sci 101: 293-299, 2010.
    • (2010) Cancer Sci , vol.101 , pp. 293-299
    • Iwatsuki, M.1    Mimori, K.2    Yokobori, T.3
  • 13
    • 84867578091 scopus 로고    scopus 로고
    • EMT-activating transcription factors in cancer: Beyond EMT and tumor invasiveness
    • Sanchez-Tillo E, Liu Y, De Barrios O, et al: EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness. Cell Mol Life Sci 69: 3429-3456, 2012.
    • (2012) Cell Mol Life Sci , vol.69 , pp. 3429-3456
    • Sanchez-Tillo, E.1    Liu, Y.2    De Barrios, O.3
  • 14
    • 84863011646 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cervical carcinoma
    • Lee MY and Shen MR: Epithelial-mesenchymal transition in cervical carcinoma. Am J Transl Res 4: 1-13, 2012.
    • (2012) Am J Transl Res , vol.4 , pp. 1-13
    • Lee, M.Y.1    Shen, M.R.2
  • 15
    • 83055176501 scopus 로고    scopus 로고
    • Correlation of TWIST2 up-regulation and epithelial-mesenchymal transition during tumoriGenesis and progression of cervical carcinoma
    • Li Y, Wang W, Wang W, et al: Correlation of TWIST2 up-regulation and epithelial-mesenchymal transition during tumoriGenesis and progression of cervical carcinoma. Gynecol Oncol 124: 112-118, 2012.
    • (2012) Gynecol Oncol , vol.124 , pp. 112-118
    • Li, Y.1    Wang, W.2    Wang, W.3
  • 16
    • 0038725013 scopus 로고    scopus 로고
    • Epithelium and fbroblast-like phenotypes derived from HPV16 E6/E7-immortalized human gingival keratinocytes following chronic ethanol treatment
    • Chamulitrat W, Schmidt R, Chunglok W, Kohl A and Tomakidi P: Epithelium and fbroblast-like phenotypes derived from HPV16 E6/E7-immortalized human gingival keratinocytes following chronic ethanol treatment. Eur J Cell Biol 82: 313-322, 2003.
    • (2003) Eur J Cell Biol , vol.82 , pp. 313-322
    • Chamulitrat, W.1    Schmidt, R.2    Chunglok, W.3    Kohl, A.4    Tomakidi, P.5
  • 17
    • 67651039345 scopus 로고    scopus 로고
    • HPV16 E7 Oncogene expression in normal human epithelial cells causes molecular changes indicative of an epithelial to mesen-chymal transition
    • Hellner K, Mar J, Fang F, Quackenbush J and Munger K: HPV16 E7 Oncogene expression in normal human epithelial cells causes molecular changes indicative of an epithelial to mesen-chymal transition. Virology 391: 57-63, 2009.
    • (2009) Virology , vol.391 , pp. 57-63
    • Hellner, K.1    Mar, J.2    Fang, F.3    Quackenbush, J.4    Munger, K.5
  • 18
    • 84862933180 scopus 로고    scopus 로고
    • The role of human papillomavirus type 16 E6/E7 oncoproteins in cervical epithelial-mesenchymal transition and carcinoGenesis
    • Cheng YM, Chou CY, Hsu YC, Chen MJ and Wing LY: The role of human papillomavirus type 16 E6/E7 oncoproteins in cervical epithelial-mesenchymal transition and carcinoGenesis. Oncol Lett 3: 667-671, 2012.
    • (2012) Oncol Lett , vol.3 , pp. 667-671
    • Cheng, Y.M.1    Chou, C.Y.2    Hsu, Y.C.3    Chen, M.J.4    Wing, L.Y.5
  • 19
    • 49349113654 scopus 로고    scopus 로고
    • Silencing of E7 Oncogene restores functional E-cadherin expression in human papil-lomavirus 16-transformed keratinocytes
    • Caberg JH, Hubert PM, Begon DY, et al: Silencing of E7 Oncogene restores functional E-cadherin expression in human papil-lomavirus 16-transformed keratinocytes. CarcinoGenesis 29: 1441-1447, 2008.
    • (2008) CarcinoGenesis , vol.29 , pp. 1441-1447
    • Caberg, J.H.1    Hubert, P.M.2    Begon, D.Y.3
  • 20
    • 77954167893 scopus 로고    scopus 로고
    • Influence of HPV16 E2 and its localisation on the expression of matrix metal-loproteinase-9
    • Mühlen S, Behren A, Iftner T and Simon C: Influence of HPV16 E2 and its localisation on the expression of matrix metal-loproteinase-9. Int J Oncol 37: 337-345, 2010.
    • (2010) Int J Oncol , vol.37 , pp. 337-345
    • Mühlen, S.1    Behren, A.2    Iftner, T.3    Simon, C.4
  • 21
    • 84883800660 scopus 로고    scopus 로고
    • Gankyrin plays an essential role in estrogen-driven and GPR30-mediated endometrial carcinoma cell proliferation via the PTEN/PI3K/AKT signaling pathway
    • Zhang J, Yang Y, Zhang Z, et al: Gankyrin plays an essential role in estrogen-driven and GPR30-mediated endometrial carcinoma cell proliferation via the PTEN/PI3K/AKT signaling pathway. Cancer Lett 339: 279-287, 2013.
    • (2013) Cancer Lett , vol.339 , pp. 279-287
    • Zhang, J.1    Yang, Y.2    Zhang, Z.3
  • 22
    • 84881533480 scopus 로고    scopus 로고
    • Study on the clinical signifcance of Argonaute2 expression in colonic carcinoma by tissue microarray
    • Wang YX, Zhang XY, Zhang BF, Yang CQ and Gao HJ: Study on the clinical signifcance of Argonaute2 expression in colonic carcinoma by tissue microarray. Int J Clin Exp Pathol 6: 476-484, 2013.
    • (2013) Int J Clin Exp Pathol , vol.6 , pp. 476-484
    • Wang, Y.X.1    Zhang, X.Y.2    Zhang, B.F.3    Yang, C.Q.4    Gao, H.J.5
  • 23
    • 79952326788 scopus 로고    scopus 로고
    • Redundant or separate entities?-roles of Twist1 and Twist2 as molecular switches during gene transcription
    • Franco HL, Casasnovas J, Rodriguez-Medina JR and Cadilla CL: Redundant or separate entities?-roles of Twist1 and Twist2 as molecular switches during gene transcription. Nucleic Acids Res 39: 1177-1186, 2011.
    • (2011) Nucleic Acids Res , vol.39 , pp. 1177-1186
    • Franco, H.L.1    Casasnovas, J.2    Rodriguez-Medina, J.R.3    Cadilla, C.L.4
  • 24
    • 67650996754 scopus 로고    scopus 로고
    • Biomarkers for epithelial-mesen-chymal transitions
    • Zeisberg M and Neilson EG: Biomarkers for epithelial-mesen-chymal transitions. J Clin Invest 119: 1429-1437, 2009.
    • (2009) J Clin Invest , vol.119 , pp. 1429-1437
    • Zeisberg, M.1    Neilson, E.G.2
  • 25
    • 70450198396 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and disease
    • Thiery JP, Acloque H, Huang RY and Nieto MA: Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-890, 2009.
    • (2009) Cell , vol.139 , pp. 871-890
    • Thiery, J.P.1    Acloque, H.2    Huang, R.Y.3    Nieto, M.A.4
  • 26
    • 84863516199 scopus 로고    scopus 로고
    • Overexpression of TWIST2 correlates with poor prognosis in head and neck squamous cell carcinomas
    • Gasparotto D, Polesel J, Marzotto A, et al: Overexpression of TWIST2 correlates with poor prognosis in head and neck squamous cell carcinomas. Oncotarget 2: 1165-1175, 2011.
    • (2011) Oncotarget , vol.2 , pp. 1165-1175
    • Gasparotto, D.1    Polesel, J.2    Marzotto, A.3
  • 27
    • 84868132835 scopus 로고    scopus 로고
    • Signifcance of heterogeneous Twist2 expression in human breast cancers
    • Mao Y, Zhang N, Xu J, Ding Z, Zong R and Liu Z: Signifcance of heterogeneous Twist2 expression in human breast cancers. PloS One 7: e48178, 2012.
    • (2012) PloS One , vol.7 , pp. e48178
    • Mao, Y.1    Zhang, N.2    Xu, J.3    Ding, Z.4    Zong, R.5    Liu, Z.6
  • 28
    • 84867870604 scopus 로고    scopus 로고
    • Loss of E-cadherin and acquisition of vimentin in epithelial-mesenchymal transition are noble indicators of uterine cervix cancer progression
    • Myong NH: Loss of E-cadherin and acquisition of vimentin in epithelial-mesenchymal transition are noble indicators of uterine cervix cancer progression. Korean J Pathol 46: 341-348, 2012.
    • (2012) Korean J Pathol , vol.46 , pp. 341-348
    • Myong, N.H.1
  • 29
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • Thiery JP and Sleeman JP: Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7: 131-142, 2006.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 30
    • 34249279527 scopus 로고    scopus 로고
    • Stability and fexibility of epigenetic gene regulation in mammalian development
    • Reik W: Stability and fexibility of epigenetic gene regulation in mammalian development. Nature 447: 425-432, 2007.
    • (2007) Nature , vol.447 , pp. 425-432
    • Reik, W.1
  • 31
    • 51049109014 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cervical cancer: Cor relation with tumor progression, epidermal growth factor receptor overexpression, and snail up-regulation
    • Lee MY, Chou CY, Tang MJ and Shen MR: Epithelial-mesenchymal transition in cervical cancer: cor relation with tumor progression, epidermal growth factor receptor overexpression, and snail up-regulation. Clin Cancer Res 14: 4743-4750, 2008.
    • (2008) Clin Cancer Res , vol.14 , pp. 4743-4750
    • Lee, M.Y.1    Chou, C.Y.2    Tang, M.J.3    Shen, M.R.4
  • 32
    • 36349005441 scopus 로고    scopus 로고
    • KCl cotransporter-3 down-regulates E-cadherin/beta-catenin complex to promote epithelial-mesenchymal transition
    • Hsu YM, Chen YF, Chou CY, et al: KCl cotransporter-3 down-regulates E-cadherin/beta-catenin complex to promote epithelial-mesenchymal transition. Cancer Res 67: 11064-11073, 2007.
    • (2007) Cancer Res , vol.67 , pp. 11064-11073
    • Hsu, Y.M.1    Chen, Y.F.2    Chou, C.Y.3
  • 33
    • 57349114162 scopus 로고    scopus 로고
    • The cell-cell adhesion molecule E-cadherin
    • Van Roy F and Berx G: The cell-cell adhesion molecule E-cadherin. Cell Mol Life Sci 65: 3756-3788, 2008.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3756-3788
    • Van Roy, F.1    Berx, G.2
  • 34
    • 84878988773 scopus 로고    scopus 로고
    • A novel function of HPV16-E6/E7 in epithelial-mesenchymal transition
    • Jung YS, Kato I and Kim HR: A novel function of HPV16-E6/E7 in epithelial-mesenchymal transition. Biochem Biophys Res Commun 435: 339-344, 2013.
    • (2013) Biochem Biophys Res Commun , vol.435 , pp. 339-344
    • Jung, Y.S.1    Kato, I.2    Kim, H.R.3
  • 35
    • 0346252339 scopus 로고    scopus 로고
    • Activity of the human papillomavirus E6 PDZ-binding motif correlates with an enhanced morphological transformation of immortalized human keratinocytes
    • Watson RA, Thomas M, Banks L and Roberts S: Activity of the human papillomavirus E6 PDZ-binding motif correlates with an enhanced morphological transformation of immortalized human keratinocytes. J Cell Sci 116: 4925-4934, 2003.
    • (2003) J Cell Sci , vol.116 , pp. 4925-4934
    • Watson, R.A.1    Thomas, M.2    Banks, L.3    Roberts, S.4
  • 36
    • 0141568874 scopus 로고    scopus 로고
    • Microarray analysis identifes differentiation-associated Genes regulated by human papillomavirus type 16 E6
    • Duffy CL, Phillips SL and Klingelhutz AJ: Microarray analysis identifes differentiation-associated Genes regulated by human papillomavirus type 16 E6. Virology 314: 196-205, 2003.
    • (2003) Virology , vol.314 , pp. 196-205
    • Duffy, C.L.1    Phillips, S.L.2    Klingelhutz, A.J.3
  • 37
    • 59549085974 scopus 로고    scopus 로고
    • Transcriptional regulation of the papillomavirus Oncogenes by cellular and viral transcription factors in cervical carcinoma
    • Thierry F: Transcriptional regulation of the papillomavirus Oncogenes by cellular and viral transcription factors in cervical carcinoma. Virology 384: 375-379, 2009.
    • (2009) Virology , vol.384 , pp. 375-379
    • Thierry, F.1
  • 38
    • 84864503594 scopus 로고    scopus 로고
    • Molecular basis of gynecological oncology-TopBP1 protein and its participation in the transcription process
    • (In Polish)
    • Forma E, Wójcik-Krowiranda K, Bienkiewicz A and Brys M: Molecular basis of gynecological oncology-TopBP1 protein and its participation in the transcription process. Ginekol Pol 83: 363-367, 2012 (In Polish).
    • (2012) Ginekol Pol , vol.83 , pp. 363-367
    • Forma, E.1    Wójcik-Krowiranda, K.2    Bienkiewicz, A.3    Brys, M.4
  • 39
    • 84879785793 scopus 로고    scopus 로고
    • Regulation of the human papillomavirus type 16 late promoter by E7 and the cell cycle
    • Bodily JM, Hennigan C, Wrobel GA and Rodriguez CM: Regulation of the human papillomavirus type 16 late promoter by E7 and the cell cycle. Virology 443: 11-19, 2013.
    • (2013) Virology , vol.443 , pp. 11-19
    • Bodily, J.M.1    Hennigan, C.2    Wrobel, G.A.3    Rodriguez, C.M.4
  • 40
    • 85056027425 scopus 로고    scopus 로고
    • Loss of HPV16 E2 protein expression without disruption of the E2 ORF correlates with carcinogenic progression
    • Xue Y, Lim D, Zhi L, He P, Abastado JP and Thierry F: Loss of HPV16 E2 protein expression without disruption of the E2 ORF correlates with carcinogenic progression. Open Virol J 6: 163-172, 2012.
    • (2012) Open Virol J , vol.6 , pp. 163-172
    • Xue, Y.1    Lim, D.2    Zhi, L.3    He, P.4    Abastado, J.P.5    Thierry, F.6
  • 41
    • 79956191057 scopus 로고    scopus 로고
    • HPV16 E2 could act as down-regulator in cellular Genes implicated in apoptosis, proliferation and cell differentiation
    • Ramirez-Salazar E, Centeno F, Nieto K, Valencia-Hernandez A, Salcedo M and Garrido E: HPV16 E2 could act as down-regulator in cellular Genes implicated in apoptosis, proliferation and cell differentiation. Virol J 8: 247, 2011.
    • (2011) Virol J , vol.8 , pp. 247
    • Ramirez-Salazar, E.1    Centeno, F.2    Nieto, K.3    Valencia-Hernandez, A.4    Salcedo, M.5    Garrido, E.6
  • 42
    • 84855205177 scopus 로고    scopus 로고
    • Tumor suppressor or Oncogene? A critical role of the human papillo-mavirus (HPV) E2 protein in cervical cancer progression
    • Bellanger S, Tan CL, Xue YZ, Teissier S and Thierry F: Tumor suppressor or Oncogene? A critical role of the human papillo-mavirus (HPV) E2 protein in cervical cancer progression. Am J Cancer Res 1: 373-389, 2011.
    • (2011) Am J Cancer Res , vol.1 , pp. 373-389
    • Bellanger, S.1    Tan, C.L.2    Xue, Y.Z.3    Teissier, S.4    Thierry, F.5


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