Induced pluripotent stem cell transplantation in the treatment of porcine chronic myocardial ischemia

Annals of Thoracic Surgery

Volumn 98, Issue 6, 2014, Pages 2130-2137

  Zhou, Yifu ^a   Wang, Suna ^a   Yu, Zuxi ^a   Hoyt, Robert F ^a   Hunt, Timothy ^a   Kindzelski, Bogdan ^a   Shou, David ^a   Xie, Wen ^a   Du, Yubin ^a   Liu, Chengyu ^a   Horvath, Keith A ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; HYPOXIA INDUCIBLE FACTOR 1BETA; KRUPPEL LIKE FACTOR 4; LENTIVIRUS VECTOR; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; SMOOTH MUSCLE ACTIN; STAGE SPECIFIC EMBRYO ANTIGEN 4; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR SOX2; VASCULOTROPIN; VON WILLEBRAND FACTOR;

ADULT; ALLOGENEIC STEM CELL TRANSPLANTATION; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL SIZE; CONTROLLED STUDY; EMBRYO; FIBROBLAST; HEART MUSCLE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; LUNG EDEMA; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SURGICAL INFECTION; ANIMAL; CELL CULTURE; DISEASE MODEL; MYOCARDIAL ISCHEMIA; PATHOLOGY; PIG; PROCEDURES; STEM CELL TRANSPLANTATION; TRANSPLANTATION; TREATMENT OUTCOME;

ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FIBROBLASTS; MYOCARDIAL ISCHEMIA; MYOCARDIUM; PLURIPOTENT STEM CELLS; STEM CELL TRANSPLANTATION; SWINE; TREATMENT OUTCOME;

EID: 84919417609     PISSN: 00034975     EISSN: 15526259     Source Type: Journal    
DOI: 10.1016/j.athoracsur.2014.07.008     Document Type: Article

References (27)

1. M.B. Britten, N.D. Abolmaali, and B. Assmus Infarct remodeling after intracoronary progenitor cell treatment in patients with acute myocardial infarction (TOPCARE-AMI): mechanistic insights from serial contrast-enhanced magnetic resonance imaging Circulation 108 2003 2212 2218
2. V. Schächinger, B. Assmus, and M.B. Britten Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction: final one-year results of the TOPCARE-AMI Trial J Am Coll Cardial 44 2004 1690 1699
3. B.E. Strauer, M. Brehm, and T. Zeus Repair of infracted myocardium by autologous intracoronary mononuclear bone marrow cell transplantation in humans Circulation 106 2002 1913 1918
4. B.E. Strauer, M. Brehm, and T. Zeus Regeneration of human infarcted heart muscle by intracoronary autologous bone marrow cell transplantation in chronic coronary artery disease: the IACT study J Am Coll Cardial 46 2005 1651 1658
5. E.C. Perin, H.F.R. Dohmann, and R. Borojevic Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure Circulation 107 2003 2294 2302
6. S. Fuchs, R. Baffour, and Y.F. Zhou Transendocardial delivery of autologous bone marrow enhances collateral perfusion and regional function in pigs with chronic experimental myocardial ischemia J Am Coll Cardiol 37 2001 1726 1732
7. S. Fuchs, L.F. Satler, and R. Kornowski Catheter-based autologous bone marrow myocardial injection in no-option patients with advanced coronary artery disease: a feasibility study J Am Coll Cardial 41 2003 1721 1724
8. S.L. Chen, W.W. Fang, and F. Ye Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction Am J Cardial 94 2004 92 95
9. P.H. Carvalho, A.P. Daibert, and B.S. Monteiro Differentiation of adipose tissue-derived mesenchymal stem cells into cardiomyocytes Arq Bras Cardiol 100 2013 82 89
10. P.L. Kang, C.H. Chen, and S.Y. Chen Nano-sized collagen I molecules enhanced the differentiation of rat mesenchymal stem cells into cardiomyocytes J Biomed Mater Res A 101 2013 2808 2816
11. S. Mohanty, S. Bose, K.G. Jain, B. Bhargava, and B. Airan TGFβ1 contributes to cardiomyogenic-like differentiation of human bone marrow mesenchymal stem cells Int J Cardiol 163 2013 93 99
12. D.S. Nascimento, D. Mosqueira, and L.M. Sousa Human umbilical cord tissue-derived mesenchymal stromal cells attenuate remodeling following myocardial infarction by pro-angiogenic, anti-apoptotic and endogenous cell activation mechanisms Stem Cell Res Ther 5 2014 5
13. S. Mureli, C.P. Gans, D.J. Bare, D.L. Geenen, N.M. Kumar, and K. Banach Mesenchymal stem cells improve cardiac conduction by upregulation of connexin 43 through paracrine signaling Am J Physiol Heart Circ Physiol 304 2013 H600 H609
14. S.M. Hashemi, S. Ghods, and F.D. Kolodgie A placebo controlled dose-ranging, safety study of allogenic mesenchymal stem cells injected by endomyocardial delivery after an acute myocardial infarction Eur Heart J 29 2008 251 259
15. F.1 Tögel, K. Weiss, Y. Yang, Z. Hu, P. Zhang, and C. Westenfelder Vasculotropic, paracrine actions of infused mesenchymal stem cells are important to the recovery from acute kidney injury Am J Physiol Renal Physiol 292 2007 F1626 F1635
16. H. Rabb Paracrine and differentiation mechanisms underlying stem cell therapy for the damaged kidney Am J Physiol Renal Physiol 289 2005 F29 F30
17. K. Takahashi, and S. Yamanaka Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors Cell 126 2006 663 676
18. K. Takahashi, K. Tanabe, and M. Ohnuki Induction of pluripotent stem cells from adult human fibroblasts by defined factors Cell 131 2007 861 872
19. J. Yu, M.A. Vodyanik, and K. Smuga-Otto Induced pluripotent stem cell lines derived from human somatic cells Science 318 2007 1917 1920
20. T. Ezashi, B.P. Telugu, A.P. Alexenko, S. Sachdev, S. Sinha, and R.M. Roberts Derivation of induced pluripotent stem cells from pig somatic cells Proc Natl Acad Sci U S A 106 2009 10993 10998
21. K. Kim, A. Doi, and B. Wen Epigenetic memory in induced pluripotent stem cells Nature 467 2010 285 290
22. O. Bar-Nur, H.A. Russ, S. Efrat, and N. Benvenisty Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells Cell Stem Cell 9 2011 17 23
23. R. Shtrichman, I. Germanguz, and J. Itskovitz-Eldor Induced pluripotent stem cells (iPSCs) derived from different cell sources and their potential for regenerative and personalized medicine Curr Mol Med 13 2013 792 805
24. Y. Zhou, S. Wang, Z. Yu, and R.F. Hoyt Jr. Direct injection of autologous mesenchymal stem cells improves myocardial function Biochem Biophys Res Commun 390 2009 902 907
25. Y. Zhou, S. Wang, Z. Yu, R.F. Hoyt Jr., X. Qu, and K.A. Horvath Marrow stromal cells differentiate into vasculature after allogeneic transplantation into ischemic myocardium Ann Thorac Surg 91 2011 1206 1212
26. E.F. Unger, S. Banai, and M. Shou A model to assess interventions to improve collateral blood flow: continuous administration of agents into the left coronary artery in dogs Cardiovasc Res 27 1993 785 791
27. S. Wang, Y. Zhou, and C.N. Seavey Rapid and dynamic alterations of gene expression profiles of adult porcine bone marrow derived stem cell in response to hypoxia Stem Cell Res 4 2010 117 128