Life-long in vivo cell-lineage tracing shows that no oogenesis originates from putative germline stem cells in adult mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 50, 2014, Pages 17983-17988

  Zhang, Hua ^a   Liu, Lian ^b   Li, Xin ^a   Busayavalasa, Kiran ^a   Shen, Yan ^a   Hovatta, Outi ^c   Gustafsson, Jan Åke ^d   Liu, Kui ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b SHANDONG UNIVERSITY   (China)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d University of Houston   (United States)

Author keywords

Follicle tracing; Genetically modified mouse models; Life long observations; No postnatal oocyte regeneration; Oocyte tracing

Indexed keywords

CRE RECOMBINASE; GROWTH DIFFERENTIATION FACTOR 9; MESSENGER RNA; TAMOXIFEN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL LINEAGE; CONTROLLED STUDY; CORPUS LUTEUM; FEMALE; GENE EXPRESSION; GENETICALLY ENGINEERED MOUSE STRAIN; GERMLINE STEM CELL; LIFESPAN; MALE; MOUSE; NONHUMAN; OOCYTE DEVELOPMENT; OVARY; PRIMORDIAL GERM CELL; REGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SOMATIC CELL; SPERMATOGENESIS; ADULT STEM CELL; ANALYSIS OF VARIANCE; ANIMAL; CROSS BREEDING; CYTOLOGY; GENE EXPRESSION PROFILING; HISTOLOGY; MUTANT MOUSE STRAIN; OOCYTE; PHYSIOLOGY; TRANSGENIC ANIMAL;

MUS;

ADULT STEM CELLS; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELL LINEAGE; CROSSES, GENETIC; FEMALE; GENE EXPRESSION PROFILING; HISTOLOGICAL TECHNIQUES; MICE; MICE, MUTANT STRAINS; OOCYTES; OOGENESIS; TAMOXIFEN;

EID: 84919401701     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1421047111     Document Type: Article

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