Simultaneous determination of twenty-two components in asari radix et rhizoma by ultra performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry

Planta Medica

Volumn 80, Issue 18, 2014, Pages 1753-1762

  Wen, Hao ^a   Gao, Hui Yuan ^a   Qi, Wen ^a   Xiao, Feng ^a   Wang, Li Li ^a   Wang, Dong ^a   Yuan, Dan ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Aristolochiaceae; aristolochic acids; Asari Radix et Rhizoma; essential oils; lignans; UHPLC QTOF MS

Indexed keywords

1 O 4 COUMAROYL XYLOPYRANOSYL GLUCOSIDE; 1 O FERULOYL XYLOPYRANOSYL GLUCOSIDE; 2 METHOXYL 4,5 METHYLENE DIOXYPROPIOPHENONE; 2 METHOXYL METHYLENEDIOXYPROPIOPHENONE; 2,4,6 TRIMETHOXYTOLUENE; 3,4,5 TRIMETHOXYTOLUENE; 4',7 DI O HEXOSIDE; AMIDE; ARISTOLOCHIC ACID; ASARI RADIX ET RHIZOMA; ASARININ; ASARUM HETEROTROPOIDES VAR. MANDSHURICUM EXTRACT; ASARUM SIEBOLDII VAR. SEOULENSE EXTRACT; ESSENTIAL OIL; FLAVANOID; HERBACEOUS AGENT; KAKUOL; LIGNAN; METHYLEUGENOL; MYRISTICIN; N ISOBUTYL DECATETRAENAMIDE; N ISOBUTYL DODECATETRAENAMIDE; NARINGENIN 5,7 DI O GLUCOSIDE; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; PLUVIATILOL; SAFROLE; SESAMIN; UNCLASSIFIED DRUG; 1,3 BENZODIOXOLE DERIVATIVE; 2-HYDROXY-4,5-METHYLENEDIOXYPROPIOPHENONE; PROPIOPHENONE DERIVATIVE;

ARTICLE; ASARUM; ASARUM HETEROTROPOIDES VAR. MANDSHURICUM; ASARUM SIEBOLDII VAR. SEOULENSE; DRUG DETERMINATION; DRUG IDENTIFICATION; HERBAL MEDICINE; NONHUMAN; PHYTOCHEMISTRY; PRINCIPAL COMPONENT ANALYSIS; QUADRUPOLE MASS SPECTROMETRY; RHIZOME; SPECIES COMPARISON; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; ULTRAVIOLET SPECTROSCOPY; CHEMISTRY; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MEDICINAL PLANT; PLANT ROOT; PROCEDURES;

ARISTOLOCHIACEAE; ASARUM; ASARUM HIMALAICUM; ASARUM SIEBOLDII;

ASARUM; BENZODIOXOLES; CHROMATOGRAPHY, LIQUID; DRUGS, CHINESE HERBAL; LIMIT OF DETECTION; MASS SPECTROMETRY; PLANT ROOTS; PLANTS, MEDICINAL; PRINCIPAL COMPONENT ANALYSIS; PROPIOPHENONES; RHIZOME; TANDEM MASS SPECTROMETRY;

EID: 84919398524     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0034-1383296     Document Type: Article

References (45)

1. Drew A. K., Whyte I. M., Bensoussan A., Dawson A. H., Zhu X., Myers S. P. Chinese herbal medicine toxicology database: monograph on herba asari, Xi Xin Clin Toxicol: 2002; 40 169 172
2. Kim S. J., Zhang C. G., Lim J. T. Mechanism of anti-nociceptive effects of Asarum sieboldii Miq. Radix: potential role of bradykinin, histamine and opioid receptor-mediated pathways. J Ethnopharmacol: 2003; 88 5 9
3. Chinese Pharmacopoeia Commission Pharmacopoeia of the People's Republic of China, Volume I. Beijing Chemical Industry Press: 2010; 214 215
4. Kosuge T., Yokota M., Nukaya H., Gotoh Y., Nagasawa M. Studies on antitussive principles of Asiasari radix. Chem Pharm Bull: 1978; 26 2284 2285
5. Dan Y., Liu H. Y., Gao W. W., Chen S. L. Activities of essential oils from Asarum heterotropoies var. mandshurium against five phytopathogens. Crop Prot: 2010; 29 295 299
6. Lee J. Y., Moon S. S., Hwang B. K. Isolation and antifungal activity of kakuol, a propiophenone derivative from Asarum sieboldii rhizome. Pest Manag Sci: 2005; 61 821 825
7. Baluchnejadmojarad T., Roghani M., Nadoushan M. RJ, Mahdavi M. RV, Kalalian-Moghaddam H., Roghani-Dehkordi F., Dariani S., Raoufi S. The sesame lignan sesamin attenuates vascular dysfunction in streptozotocin diabetic rats: Involvement of nitric oxide and oxidative stress. Eur J Pharmacol: 2013; 698 316 321
8. Quang T. H., Ngan N. TT, Minh C. V., Kiem P. V., Tai B. H., Thao N. P., Song S. B., Kim Y. H. Anti-inflammatory and PPAR transactivational effects of secondary metabolites from the roots of Asarum sieboldii. Bioorg Med Chem Lett: 2012; 22 2527 2533
9. Li C., Xu F., Cao C., Shang M. Y., Zhang C. Y., Yu J., Liu G. X., Wang X., Cai S. Q. Comparative analysis of two species of Asari Radix et Rhizoma by electronic nose, head space GC-MS and chemometrics. J Pharmaceut Biomed: 2013; 2 231 238
10. Yasuda I., Takeya K., Itokawa H. Structures of amides from Asiasarum heterotropoides Maek. var. mandshuricum Maek. Chem Pharm Bull: 1981; 29 564 566
11. Han A. R., Kim H. J., Shin M., Hong M., Kim Y. S., Bae H. Constituents of Asarum sieboldii with inhibitory activity on lipopolysaccharide (LPS)-induced NO production in BV-2 microglial cells. Chem Biodivers: 2008; 5 346 351
12. Cai S. Q., Wang X., Zhu S., Li J. S., Lou Z. Q., Namba T., Komatsu K. Studies on botanical origin of commercial samples of traditional Chinese drug Xixin (Herba Asari). Chin J Chin Mater Med: 1996; 21 712 717 760
13. Li Y. L., Yu J., Cao C., Xie B. B., Zhang C. Y., Liu Z., Shang M. Y., Wang X., Cai S. Q. Survey on resources and varietie on Chinese markets of crude drug Xixin. Chin J Chin Mater Med: 2010; 35 3237 3241
14. Cai S. Q., Yu J., Wang X., Wang R. Q., Ran F. X., Shang M. Y., Cui J. R., Komatsu K., Namba T. Cytotoxic activity of some Asarum plants. Fitoterapia: 2008; 79 293 297
15. Xie B. B., Shang M. Y., Wang X., Cai S. Q., Lee K. H. A new aristolochic acid derivative from Asarum himalaicum. Acta Pharm Sin: 2011; 46 188 192
16. Xie Y. Y., Qu J. L., Wang Q. L., Wang Y., Yoshikawa M., Yuan D. Comparative evaluation of cultivars of Chrysanthemum morifolium flowers by HPLC-DAD-ESI/MS analysis and antiallergic assay. J Agric Food Chem: 2012; 60 12574 12583
17. Wang G. F., Zhang S. R., Zhu S. Q. Determination of L-sesamin and L-asarinin in Asarum heterotropoides Fr. Schmidt var. mandshuricum (Maxim.) Kitag. by HPLC. Chin J Pharm Anal: 1999; 19 251 253
18. Zhang L., Chen X. H., Liu Y. L., Zhang J., Bi K. S. Simultaneous determination of L-asarinin, L-sesamin and kakuol in Asarum heterotropoides by RP-HPLC. Chin Tradit Herbal Drugs: 2008; 39 1098 1100
19. Liu Y. H., Yi J. H., Huang J., Huang Z. F., Liu Y. H. RP-HPLC simultaneous determination of methyleugenol, safrole and asarinin in Asari Radix et Rhizoma. Chin J Pharm Anal: 2012; 32 822 825
20. Zhao Z. Z., Liang Z. T., Jiang Z. H., Leung K. SY, Chan C. L., Chan H. Y., Sin J., Man T. O., Law K. W. Comparative study on the aristolochic acid I content of Herba Asari for safe use. Phytomedicine: 2008; 15 741 748
21. The Ministry of Health, Labour and Welfare Japanese Pharmacopeia, 16th edition. Tokyo The Ministry of Health, Labour and Welfare: 2011; 1602 1603
22. Hashimoto K., Higuchi M., Makino B., Sakakibara I., Kubo M., Komatsu Y., Maruno M., Okada M. Quantitative analysis of aristolochic acids, toxic compounds, contained in some medicinal plants. J Ethnopharmacol: 1999; 64 185 189
23. Jong T. T., Lee M. R., Hsiao S. S., Hsai J. L., Wu T. S., Chiang S. T., Cai S. Q. Analysis of aristolochic acid in nine sources of Xixin, a traditional Chinese medicine, by liquid chromatography/atmospheric pressure chemical ionization/tandem mass spectrometry. J Pharmaceut Biomed: 2003; 33 831 837
24. Yuan J., Liu Q., Zhu W., Ding L., Tang F., Yao S. Simultaneous analysis of six aristolochic acids and five aristolactams in herbal plants and their preparations by high-performance liquid chromatography-diode array detection-fluorescence detection. J Chromatogr A: 2008; 1182 85 92
25. Li J., Zhang L., Jiang Z. Z., Shu B., Li F., Bao Q., Zhang L. Y. Toxicities of aristolochic acid I and aristololactam I in cultured renal epithelial cells. Toxicol In Vitro: 2012; 24 1092 1097
26. Balachandran P., Wei F., Lin R. C., Khan I. A., Pasco D. S. Structure activity relationships of aristolochic acid analogues: Toxicity in cultured renal epithelial cells. Kidney Int: 2005; 67 1797 1805
27. Sato N., Takahashi D., Chen S. M., Tsuchiya R., Mukoyama T., Yamagata S. I., Ogawa M., Yoshida M., Kondo S., Satoh N., Ueda S. Acute nephrotoxicity of aristolochic acids in mice. J Pharm Pharmacol: 2004; 56 221 229
28. Tistaert C., Dajaegher B., Heyden Y. V. Chromatographic separation techniques and handing methods for herbal fingerprints: A review. Anal Chim Acta: 2011; 902 148 161
29. Zhang A., Sun H., Wang P., Han Y., Wang X. Modern analytical techniques in metabolomics analysis. Analyst: 2012; 137 293 300
30. Yamamoto H., Kuribayashi H., Seshima Y., Zhao P., Kouno I., Taguchi G., Shimomura K. Metabolism of administered (2 RS)-naringenin in flavonoid-producing cultured cells of Sophora flavescens. Plant Biotechnol: 2004; 21 355 359
31. Chen J. W., Wu L. L., Li X., Zhou H. Y., Wu T. Z. GC-MS analysis of volatile components in supercritical fluid extracts of the root and rhizome of Asarum heterotropoides Fr. var. mandshuricum. Nat Prod Res Dev: 2012; 24 195 198
32. Bijak M., Saluk J., Tsirigotis-Maniecka M., Komorowska H., Wachowicz B., Zacynska E., Czarny A., Czechowski F., Nowak P., Pawlaczyk I. The influence of conjugates isolated from Matricaria chamomilla L. on platelets activity and cytotoxicity. Int J Biol Macromol: 2013; 61 218 229
33. Luo X. B., Chen B., Yao S. Z., Zeng J. G. Simultaneous analysis of caffeic acid derivatives and alkamides in roots and extracts of Echinacea purpurea by high-performance liquid chromatography-photodiode array detection-electrospray mass spectrometry. J Chromatogr A: 2003; 986 73 81
34. Zhang Y., Shi W., Xi T., Zhang Y., Zhou W. Synthesis and antifungal activity of 1-(2-acyloxy-4, 5-methylenedioxy)phenyl-2-methyl propylene ketones. Chin J Pestic Sci: 2012; 14 95 98
35. Jiang Y., Liu G. Q., Ma J. R., Xie L., Wu H. Q. The pharmacological studies on methyleugenol. Acta Pharm Sin: 1982; 17 87 92
36. Zhou H. Q., Yu B., Qiao W. H., Wang D. Y., Zhang W. R., Bai Y., Su Y. M. Research on pharmacological activities of methyleugenol. Acta Chin Med Pharm: 2000; 28 79 80
37. Sun Q., Wu Y., Jia L. Quantitative Determination of Aristolochic Acid in Asarum heterotropoides Fr. Schmidt var. mandshuricum (Maxim.) Kitag. Asian J Tradit Med: 2006; 1 5 13
38. Chen J., Sun B. H., Huang J., Gao H. Y., Wang J. Q., Wu L. J. Determination of aristolochic acid IVA in the different part of Asarum heterotropoides Fr. Schmidt var. mandshuricum (Maxim.) Kitag. by HPLC. J Shenyang Pharm Univ: 2011; 28 797 800
39. Goey A. KL, Rosing H., Meijerman I., Sparidans R. W., Schellens J. HM, Beijnen J. H. The bioanalysis of the major Echinacea purpurea constituents dodeca-2 E,4 E,8 Z,10 E / Z -tetraenoic acid isobutylamides in human plasma using LC-MS/MS. J Chromatogr B: 2012; 902 151 156
40. Gallo M., Ferracane R., Naviglio D. Antioxidant addition to prevent lipid and protein oxidation in chicken meat mixed with supercritical extracts of Echinacea angustifolia. J Supercrit Fluid: 2012; 72 198 204
41. Lv S., Xu L., Huang J., Gao H. Y., Wu L. J. Chemical constituents of the root of Asarum heterotropoides Fr. Schmidt var. mandshuricum (Maxim.) Kitag. J Shenyang Pharm Univ: 2008; 25 702 704
42. Qi W., Wang L. L., Wen H., Zhang L., Yuan D. Isolation and identification of chemical constituents in roots and rhizomes of Asarum heterotropoides Fr. Schmidt var. mandshuricum (Maxim.) Kitag. J Shenyang Pharm Univ: 2014; 31 681 686
43. Kong L. Studies on quality evaluation of Chinese Echinacea purpurea [master]. Shenyang Shenyang Pharmaceutical University: 2006
44. Delectis Florae Reipublicae Popularis Sinicae Agendae Academiae Sinicae Edita Flora Reipublicae Popularis Sinicae, Tomus 24. Beijing Science Press: 1988; 176 177
45. Liu Q., Shi Y., Wang Y., Lu J., Cong W., Luo G., Wang Y. Metabolism profile of scutellarin in urine following oral administration to rats by ultra performance liquid chromatography coupled to time-of-flight mass spectrometry. Talanta: 2009; 80 84 91