Detection of hepatocellular carcinoma in transgenic mice by Gd-DTPA- and rhodamine 123-conjugated human serum albumin nanoparticles in T1 magnetic resonance imaging

Journal of Controlled Release

Volumn 199, Issue , 2015, Pages 63-71

  Watcharin, Waralee ^a   Schmithals, Christian ^b   Pleli, Thomas ^b   Köberle, Verena ^b   Korkusuz, Hüdayi ^b   Hübner, Frank ^b   Waidmann, Oliver ^b   Zeuzem, Stefan ^b   Korf, Horst Werner ^b   Terfort, Andreas ^a   Gelperina, Svetlana ^c   Vogl, Thomas J ^b   Kreuter, Jörg ^a   Piiper, Albrecht ^b  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^c Nanosystem LTD   (Russian Federation)

Author keywords

Gadolinium; HCC; Macrophages; MRI; Nanoparticle; Targeting

Indexed keywords

BODY FLUIDS; COATINGS; DIAGNOSIS; GADOLINIUM; MACROPHAGES; MAMMALS; NANOMAGNETICS; NANOPARTICLES; SIGNAL SYSTEMS; TUMORS;

DIETHYLENETRIAMINE PENTA-ACETIC ACIDS; DIFFERENTIAL DIAGNOSIS; HCC; HEPATOCELLULAR CARCINOMA; IMMUNOHISTOCHEMICAL ANALYSIS; INTRAVENOUS INJECTIONS; T1-WEIGHTED MAGNETIC RESONANCE IMAGING; TARGETING;

MAGNETIC RESONANCE IMAGING;

GADOLINIUM PENTETATE; GADOXETIC ACID; HUMAN SERUM ALBUMIN; POLOXAMINE 908; RHODAMINE 123; CONTRAST MEDIUM; ETHYLENEDIAMINE DERIVATIVE; EXCIPIENT; MACROGOL DERIVATIVE; NANOPARTICLE; SERUM ALBUMIN; TETRONIC 701; TRANSFORMING GROWTH FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER DIAGNOSIS; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; LIVER; LIVER CELL CARCINOMA; MACROPHAGE; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; TUMOR LOCALIZATION; ANIMAL; CARCINOMA, HEPATOCELLULAR; CELL SURVIVAL; DRUG EFFECTS; GENETICS; HUMAN; LIVER NEOPLASMS; ONCOGENE MYC; PARTICLE SIZE; PATHOLOGY; PERITONEUM MACROPHAGE; PROCEDURES; TISSUE DISTRIBUTION; TRANSGENIC MOUSE;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL SURVIVAL; CONTRAST MEDIA; ETHYLENEDIAMINES; EXCIPIENTS; GADOLINIUM DTPA; GENES, MYC; HUMANS; LIVER; LIVER NEOPLASMS; MACROPHAGES, PERITONEAL; MAGNETIC RESONANCE IMAGING; MICE; MICE, TRANSGENIC; NANOPARTICLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; RHODAMINE 123; SERUM ALBUMIN; TISSUE DISTRIBUTION; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 84918819855     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.11.023     Document Type: Article

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