Variation at ABO histo-blood group and FUT loci and diffuse and intestinal gastric cancer risk in a European population

International Journal of Cancer

Volumn 136, Issue 4, 2015, Pages 880-893

  Duell, Eric J ^a   Bonet, Catalina ^a   Muñoz, Xavier ^a   Lujan Barroso, Leila ^a   Weiderpass, Elisabete ^b,c,d,e   Boutron Ruault, Marie Christine ^f,g,h   Racine, Antoine ^f,g,h   Severi, Gianluca ^i,j   Canzian, Federico ^k   Rizzato, Cosmeri ^k   Boeing, Heiner ^l   Overvad, Kim ^m   Tjønneland, Anne ⁿ   Argüelles, Marcial ^o   Sáanchez Cantalejo, Emilio ^p,q,r   Chamosa, Saioa ^s   Huerta, Josée Maríia ^q,t   Barricarte, Aurelio ^q,u   Khaw, Kay Tee ^v   Wareham, Nick ^w   Travis, Rutch C ^x   Trichopoulou, Antonia ^y,z   Trichopoulos, Dimitrios ^y,z,aa   Yiannakouris, Nikos ^y,ab   Palli, Domenico ^ac   Agnoli, Claudia ^ad   Tumino, Rosario ^ae   Naccarati, Alessio ^af   Panico, Salvatore ^ag   Bueno De Mesquita, H B ^ah,ai,aj   Siersema, Peter D ^ai   Peeters, Petra H M ^ai,aj   Ohlsson, Bodil ^ak   Lindkvist, Björn ^al   Johansson, Ingegerd ^d,am   Ye, Weimin ^d,an   Johansson, Matthias ^ao   Fenger, Claus ^aj   Riboli, Elio ^aj   Sala, Núria ^a   González, Carlos A ^a   more..

^a CATALAN INSTITUTE OF ONCOLOGY   (Spain)

^b UNIVERSITY OF TROMSØ   (Norway)

^c CANCER REGISTRY OF NORWAY   (Norway)

^d KAROLINSKA INSTITUTE   (Sweden)

^e FOLKHÄLSAN RESEARCH CENTER   (Finland)

^f INSERM   (France)

^g UNIVERSITÉ PARIS SACLAY   (France)

^h IGR   (France)

ⁱ CANCER EPIDEMIOLOGY CENTRE   (Australia)

^j UNIVERSITY OF MELBOURNE   (Australia)

^k GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^l GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^m AARHUS UNIVERSITY   (Denmark)

ⁿ INSTITUTE OF CANCER EPIDEMIOLOGY   (Denmark)

^o Public Health Directorate   (Spain)

^p ANDALUSIAN SCHOOL OF PUBLIC HEALTH   (Spain)

^q CIBER EPIDEMIOLOGÍA Y SALUD PÚBLICA CIBERESP   (Spain)

^r Instituto De Investigación Biosanitaria de Granada Ibs GRANADA   (Spain)

^s BIODONOSTIA HEALTH RESEARCH INSTITUTE   (Spain)

^t DEPARTMENT OF EPIDEMIOLOGY   (Spain)

^u INSTITUTO DE SALUD PÚBLICA DE NAVARRA   (Spain)

^v UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^w ADDENBROOKE S HOSPITAL   (United Kingdom)

^x UNIVERSITY OF OXFORD   (United Kingdom)

^y HELLENIC HEALTH FOUNDATION   (Greece)

^z BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^aa HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^ab HAROKOPIO UNIVERSITY   (Greece)

^ac CANCER RESEARCH AND PREVENTION INSTITUTE ISPO   (Italy)

^ad NATIONAL CANCER INSTITUTE   (Italy)

^ae Cancer Registry and Histopathology Unit   (Italy)

^af Human Genetics Foundation   (Italy)

^ag UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^ah NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^ai UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^aj IMPERIAL COLLEGE LONDON   (United Kingdom)

^ak LUND UNIVERSITY HOSPITAL   (Sweden)

^al UNIVERSITY OF GOTHENBURG   (Sweden)

^am UMEÅ UNIVERSITY   (Sweden)

^an INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^ao ODENSE UNIVERSITY HOSPITAL   (Denmark)

more..

Author keywords

ABO; Blood group; FUT; Gastric cancer; Genetic susceptibility

Indexed keywords

FUCOSYLTRANSFERASE; BLOOD GROUP ABO SYSTEM;

ABO GENE; ADULT; ARTICLE; BLOOD GROUP A; BLOOD GROUP ABO SYSTEM; CANCER RISK; CARCINOGENESIS; CONTROLLED STUDY; EUROPEAN; FEMALE; FUT GENE; FUT2 GENE; FUT3 GENE; FUT5 GENE; FUT6 GENE; GENE; GENE FREQUENCY; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HAPLOTYPE; HELICOBACTER INFECTION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; STOMACH CANCER; ADENOCARCINOMA; AGED; CASE CONTROL STUDY; CLINICAL TRIAL; ENZYMOLOGY; EUROPE; GENETIC PREDISPOSITION; GENETICS; MIDDLE AGED; MULTICENTER STUDY; PROSPECTIVE STUDY; RISK; STOMACH TUMOR;

ABO BLOOD-GROUP SYSTEM; ADENOCARCINOMA; AGED; CASE-CONTROL STUDIES; EUROPE; FEMALE; FUCOSYLTRANSFERASES; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; RISK; STOMACH NEOPLASMS;

EID: 84918818967     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.29034     Document Type: Article

References (41)

1. Aird I, Bentall HH, Roberts JA. A relationship between cancer of stomach and the ABO blood groups. Br Med J 1953;1:799-801
2. Wang Z, Liu L, Ji J, et al. ABO blood group system and gastric cancer: A case-control study and meta-analysis. Int J Mol Sci 2012;13:13308-21
3. Edgren G, Hjalgrim H, Rostgaard K, et al. Risk of gastric cancer and peptic ulcers in relation to ABO blood type: A cohort study. Am J Epidemiol 2010;172:1280-5
4. Martins LC, de Oliveira Corvelo TC, Oti HT, et al. ABH and Lewis antigen distributions in blood, saliva and gastric mucosa and H pylori infection in gastric ulcer patients. World J Gastroenterol 2006;12:1120-4
5. Aspholm-Hurtig M, Dailide G, Lahmann M, et al. Functional adaptation of BabA, the H. pylori ABO blood group antigen binding adhesin. Science 2004;305:519-22
6. Boren T, Falk P, Roth KA, et al. Attachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens. Science 1993; 262:1892-5
7. Mahdavi J, Sonden B, Hurtig M, et al. Helicobacter pylori SabA adhesin in persistent infection and chronic inflammation. Science 2002;297:573-8
8. Polk DB, Peek RM, Jr. Helicobacter pylori: gastric cancer and beyond. Nat Rev Cancer 2010;10:403- 14
9. Polk DB, Peek RM, Jr.,Erratum appears in: Nat Rev Cancer 2010;10: 593
10. Naitza S, Porcu E, Steri M, et al. A genome-wide association scan on the levels of markers of inflammation in Sardinians reveals associations that underpin its complex regulation. PLoS Genet 2012;8:e1002480
11. Pare G, Chasman DI, Kellogg M, et al. Novel association of ABO histo-blood group antigen with soluble ICAM-1: Results of a genome-wide association study of 6,578 women. PLoS Genet 2008;4:e1000118
12. Amundadottir L, Kraft P, Stolzenberg-Solomon RZ, et al. Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet 2009;41:986-90
13. Nakao M, Matsuo K, Ito H, et al. ABO genotype and the risk of gastric cancer, atrophic gastritis, and Helicobacter pylori infection. Cancer Epidemiol Biomarkers Prev 2011;20:1665-72
14. Song HR, Shin MH, Kim HN, et al. Sex-specific differences in the association between ABO genotype and gastric cancer risk in a Korean population. Gastric Cancer 2013;16:254-60
15. Wolpin BM, Kraft P, Gross M, et al. Pancreatic cancer risk and ABO blood group alleles: Results from the pancreatic cancer cohort consortium. Cancer Res 2010;70:1015-23
16. Wolpin BM, Kraft P, Xu M, et al. Variant ABO blood group alleles, secretor status, and risk of pancreatic cancer: Results from the pancreatic cancer cohort consortium. Cancer Epidemiol Biomarkers Prev 2010;19:3140-9
17. Wu C, Miao X, Huang L, et al. Genome-wide association study identifies five loci associated with susceptibility to pancreatic cancer in Chinese populations. Nat Genet 2012;44:62-6
18. Risch HA, Lu L, Wang J, et al. ABO blood group and risk of pancreatic cancer: A study in shanghai and meta-analysis. Am J Epidemiol 2013;177: 1326-37
19. Hazra A, Kraft P, Selhub J, et al. Common variants of FUT2 are associated with plasma vitamin B12 levels. Nat Genet 2008;40:1160-2
20. Hazra A, Kraft P, Lazarus R, et al. Genome-wide significant predictors of metabolites in the onecarbon metabolism pathway. Hum Mol Genet 2009;18:4677-87
21. Tanaka T, Scheet P, Giusti B, et al. Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations. Am J Hum Genet 2009;84:477-82
22. Tanwar VS, Chand MP, Kumar J, et al. Common variant in FUT2 gene is associated with levels of vitamin B(12) in Indian population. Gene 2013; 515:224-8
23. Riboli E, Hunt KJ, Slimani N, et al. European Prospective Investigation into Cancer and Nutrition (EPIC): Study populations and data collection. Public Health Nutr 2002;5:1113-24
24. Lauren P. The two histological main types of gastric carcinoma: Diffuse and so-called intestinaltype carcinoma. An attempt at a histo-clinical classification. Acta Pathol Microbiol Scand 1965; 64:31-49
25. Carneiro F, Moutinho C, Pera G, et al. Pathology findings and validation of gastric and esophageal cancer cases in a European cohort (EPIC/EURGAST). Scand J Gastroenterol 2007;42:618-27
26. Sala N, Munoz X, Travier N, et al. Prostate stemcell antigen gene is associated with diffuse and intestinal gastric cancer in Caucasians: Results from the EPIC-EURGAST study. Int J Cancer 2012;130:2417-27
27. Gonzalez CA, Megraud F, Buissonniere A, et al. Helicobacter pylori infection assessed by ELISA and by immunoblot and noncardia gastric cancer risk in a prospective study: The Eurgast-EPIC project. Ann Oncol 2011;23:1320-4
28. Palli D, Masala G, Del Giudice G, et al. CagA1 Helicobacter pylori infection and gastric cancer risk in the EPIC-EURGAST study. Int J Cancer 2007;120:859-67
29. Bernstein F. Fortgesetzte Untersuchungen aus der Theorie der Blutgruppen Continued Investigations in the Theory of Blood Groups. Z Indukt Abstamm Vererungsl 1930;56:233-73
30. Dudbridge F, Koeleman BP. Efficient computation of significance levels for multiple associations in large studies of correlated data, including genomewide association studies. Am J Hum Genet 2004;75:424-35
31. Gonzalez JR, Armengol L, Sole X, et al. SNPassoc: An R package to perform whole genome association studies. Bioinformatics 2007;23:644-5
32. Patnaik SK, Helmberg W, Blumenfeld OO. BGMUT: NCBI dbRBC database of allelic variations of genes encoding antigens of blood group systems. Nucleic Acids Res 2012;40(Database issue):D1023-9
33. Silva LM, Carvalho AS, Guillon P, et al. Infection- associated FUT2 (Fucosyltransferase 2) genetic variation and impact on functionality assessed by in vivo studies. Glycoconj J 2010;27: 61-8
34. Serpa J, Mesquita P, Mendes N, et al. Expression of Lea in gastric cancer cell lines depends on FUT3 expression regulated by promoter methylation. Cancer Lett 2006;242:191-7
35. Carvalho AS, Harduin-Lepers A, Magalhaes A, et al. Differential expression of alpha-2,3- sialyltransferases and alpha-1,3/4-fucosyltransferases regulates the levels of sialyl Lewis a and sialyl Lewis x in gastrointestinal carcinoma cells. Int J Biochem Cell Biol 2010;42:80-9
36. Padro M, Cobler L, Garrido M, et al. Down-regulation of FUT3 and FUT5 by shRNA alters Lewis antigens expression and reduces the adhesion capacities of gastric cancer cells. Biochim Biophys Acta 2011;1810:1141-9
37. Padro M, Mejias-Luque R, Cobler L, et al. Regulation of glycosyltransferases and Lewis antigens expression by IL-1beta and IL-6 in human gastric cancer cells. Glycoconj J 2011;28:99-110
38. Gerhard M, Lehn N, Neumayer N, et al. Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin. Proc Natl Acad Sci USA 1999;96:12778-83
39. Sheu BS, Sheu SM, Yang HB, et al. Host gastric Lewis expression determines the bacterial density of Helicobacter pylori in babA2 genopositive infection. Gut 2003;52:927-32
40. Lee HS, Choe G, Kim WH, et al. Expression of Lewis antigens and their precursors in gastric mucosa: Relationship with Helicobacter pylori infection and gastric carcinogenesis. J Pathol 2006;209:88-94
41. Monteiro MA, Zheng P, Ho B, et al. Expression of histo-blood group antigens by lipopolysaccharides of Helicobacter pylori strains from asian hosts: The propensity to express type 1 bloodgroup antigens. Glycobiology 2000;10:701-13.