Curcumin's neuroprotective efficacy in Drosophila model of idiopathic parkinson's disease is phase specific: Implication of its therapeutic effectiveness

Rejuvenation Research

Volumn 17, Issue 6, 2014, Pages 481-489

  Phom, Limamanen ^a   Achumi, Bovito ^a   Alone, Debasmita P ^b   Muralidhara, ^c   Yenisetti, Sarat Chandra ^a  

^a NAGALAND UNIVERSITY   (India)

^b NATIONAL INSTITUTE OF SCIENCE EDUCATION AND RESEARCH   (India)

^c CENTRAL FOOD TECHNOLOGICAL RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CURCUMIN; DOPAMINE; NEUROPROTECTIVE AGENT; PARAQUAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CLIMBING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DEVELOPMENTAL STAGE; DOPAMINE BRAIN LEVEL; DOPAMINERGIC NERVE CELL; DRUG EFFICACY; EARLY HEALTH STAGE; FRUIT FLY MODEL; GENE EXPRESSION; GROWTH CURVE; IDIOPATHIC DISEASE; IMMOBILITY; LATE HEALTH STAGE; LIFE CYCLE STAGE; LONGEVITY; MALE; MOTOR DYSFUNCTION; NERVE CELL DEGENERATION; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; SENESCENCE; SURVIVAL RATE; TRANSITION PHASE; ANIMAL; BRAIN; CHEMISTRY; DISEASE MODEL; DOSE RESPONSE; DROSOPHILA MELANOGASTER; DRUG EFFECTS; DRUG RESISTANCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; METABOLISM; MOVEMENT (PHYSIOLOGY); PATHOPHYSIOLOGY; TIME; TREATMENT OUTCOME;

ANIMALS; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CURCUMIN; DISEASE MODELS, ANIMAL; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DROSOPHILA MELANOGASTER; DRUG RESISTANCE; HUMANS; LONGEVITY; MOVEMENT; NEUROPROTECTIVE AGENTS; PARAQUAT; PARKINSON DISEASE; TIME FACTORS; TREATMENT OUTCOME;

EID: 84918817438     PISSN: 15491684     EISSN: 15578577     Source Type: Journal    
DOI: 10.1089/rej.2014.1591     Document Type: Article

References (24)

1. Polymeropoulos MH, Higgins JJ, Golbe LI, Johnson WG, Ide SE, Di Iorio G, Sanges G, Stenroos ES, Pho LT, Schaffer AA, Lazzarini AM, Nussbaum RL, Duvoisin RC. Mapping of a gene for Parkinson's disease to chromosome 4q21-q23. Science 1996;274:1197-1199.
2. Tapias V, Cannon JR, Greenamyre JT. Pomegranate juice exacerbates oxidative stress and nigrostriatal degeneration in Parkinson's disease. Neurobiol Aging 2014;35:1162-1176.
3. Gorell JM, Johnson CC, Rybicki BA, Peterson EL, Richardson RJ. The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living. Neurology 1998;50:1346-1350.
4. Vanacore N, Nappo A, Gentile M, Brustolin A, Palange S, Liberati A, Di Rezze S, Caldora G, Gasparini M, Benedetti F, Bonifati V, Forastiere F, Quercia A, Meco G. Evaluation of risk of Parkinson's disease in a cohort of licensed pesticide users. Neurol Sci 2002;23:2:S119-S120.
5. Uversky VN. Neurotoxicant-induced animal models of Parkinson's disease: Understanding the role of rotenone, maneb and paraquat in neurodegeneration. Cell Tissue Res 2004;318:225-241.
6. Berry C, La Vecchia C, Nicotera P. Paraquat and Parkinson's disease. Cell Death Differ 2010;1115-1125.
7. Shimizu K, Matsubara K, Ohtaki K, Fujimaru S, Saito O, Shiono H. Paraquat induces long-lasting dopamine overflow through the excitotoxic pathway in the striatum of freely moving rats. Brain Res 2003;976:243-252.
8. Yumino K, Kawakami L, Tamura M, Hayashi T, Nakamura M. Paraquat- and diquat-induced oxygen radical generation and lipid peroxidation in rat brain microsomes. J Biochem 2002;131:565-570.
9. Mythri RB, Bharath MMS Curcumin: A potential neuroprotective agent in Parkinson's disease. Curr Pharm Des 2012;18:91-99.
10. Shen LR, Parnell LD, Ordovas JM, Lai CQ. Curcumin and aging. Biofactors 2013;39:133-140.
11. Maruta H. Herbal therapeutics that block the oncogenic kinase PAK1: A practical approach towards PAK1- dependent diseases and longevity. Phytother Res 2014;28: 656-672.
12. Lee S, Bang SM, Lee JW, Cho KS. Evaluation of traditional medicines for neurodegenerative diseases using Drosophila models. Evid Based Complement Alternat Med 2014;2014:1-14.
13. Sahdeo P, Tyagi AK, Aggarwal BB. Recent developments in delivery, bioavailability, absorption and metabolism of Curcumin: The golden pigment from golden spice. Cancer Res Treat 2014;46:2-18.
14. Wang MS, Boddapati S, Emadi S, Sierks MR. Curcumin reduces alpha-synuclein induced cytotoxicity in Parkinson's disease cell model. BMC Neurosci 2010;30:11:57.
15. Liu Z, Yu Y, Li X, Ross CA, Smith WW. Curcumin protects against A53T alpha-synuclein-induced toxicity in a PC12 inducible cell model for Parkinsonism. Pharmacol Res 2011;63:439-444.
16. Lee KS, Lee BS, Semnani S, Avanesian A, Um CY, Jeon HJ, Seong KM, Yu K, Min KJ, Jafari M. Curcumin extends life span, improves health span and modulates the expression of age associated aging genes in Drosophila melanoasger. Rejuvenation Res 2010;13:561-570.
17. Park JH, Jung JW, Ahn YJ, Kwon HW. Neuroprotective properties of phytochemicals against paraquatinduced oxidative stress and neurotoxicity in Drosophila melanogaster. Pestic Biochem Physiol 2012;104:118- 225.
18. Arking R, Novoseltseva J, Hwangho DS, Novoseltsev V, Lane M. Different age specific demographic profiles are generated in the same normal-lived Drosophila strain by different longevity stimuli. J Gerontol A Biol Sci Med Sci 2002;57:B390-B398.
19. Pletcher SD, Macdonald SJ, Marguerie R, Certa U, Stearns SC, Goldstein DB, Partridge L. Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster. Curr Biol 2002;12:712-723.
20. Soh JW, Marowsky N, Nichols TJ, Rahman AM, Miah T, Sarao P, Khasawneh R, Unnikrishnan A, Heydari AR, Silver RB, Arking R. Curcumin is an early-acting stagespecific inducer of extended functional longevity in Drosophila. Exp Gerontol 2013;48:229-239.
21. Luckinbill IS, Arking R, Clare M, Cirocco W, Buck S. Selection of delayed senescence in Drosophila melanogaster. Evolution 1984;38:996-1003.
22. Botella JA, Ulschmid JK, Gruenewald C, Moehle C, Kretzschmar D, Becker K, Schneuwly S. The Drosophila carbonyl reductase sniffer prevents oxidative stress-induced neurodegeneration. Curr Biol 2004;14:782-786.
23. Zhao HL, Song CH and Chai OH. Negative effects of curcumin on liver injury induced by alcohol. Phytother Res 2012;26:1857-1863.
24. Inamdar AA, Chaudhari A, O'Donnell. The protective effect of minocycline in a paraquat induced Parkinson's disease model in Drosophila is modified in altered genetic backgrounds. Parkinson's Dis 2012;2012: http://dx.doi.org/ 10.1155/2012/938528