MiR-184 regulates ezrin, LAMP-1 expression, affects phagocytosis in human retinal pigment epithelium and is downregulated in age-related macular degeneration

FEBS Journal

Volumn 281, Issue 23, 2014, Pages 5251-5264

  Murad, Najiba ^a   Kokkinaki, Maria ^b   Gunawardena, Nishantha ^a   Gunawan, Mia S ^a   Hathout, Yetrib ^c   Janczura, Karolina J ^a   Theos, Alexander C ^a   Golestaneh, Nady ^a,b  

^a GEORGETOWN UNIVERSITY   (United States)

^b GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^c CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

Author keywords

AMD; Ezrin; LAMP 1; MiR 184; RPE

Indexed keywords

EZRIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MICRORNA; MICRORNA 184; UNCLASSIFIED DRUG; CYTOSKELETON PROTEIN; LAMP1 PROTEIN, HUMAN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN; MIRN184 MICRORNA, HUMAN;

ADULT; AGE RELATED MACULAR DEGENERATION; ARTICLE; CELL FUNCTION; CONTROLLED STUDY; DOWN REGULATION; EZR GENE; GENE CONTROL; GENE FUNCTION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC CONSERVATION; HUMAN; HUMAN CELL; PATHOPHYSIOLOGY; PHAGOCYTOSIS; PIGMENT EPITHELIUM; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEOMICS; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION; ADOLESCENT; AGED; CELL CULTURE; CHILD; FEMALE; GENETICS; MACULAR DEGENERATION; MALE; METABOLISM; MIDDLE AGED; PHOTORECEPTOR OUTER SEGMENT; PHYSIOLOGY; VERY ELDERLY;

DANIO RERIO;

ADOLESCENT; AGED; AGED, 80 AND OVER; CELLS, CULTURED; CHILD; CYTOSKELETAL PROTEINS; DOWN-REGULATION; FEMALE; HUMANS; LYSOSOME-ASSOCIATED MEMBRANE GLYCOPROTEINS; MACULAR DEGENERATION; MALE; MICRORNAS; MIDDLE AGED; PHAGOCYTOSIS; RETINAL PHOTORECEPTOR CELL OUTER SEGMENT; RETINAL PIGMENT EPITHELIUM;

EID: 84918815517     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.13066     Document Type: Article

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